Displaying drugs 101 - 125 of 2923 in total
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Mixtures name: … EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET …
Vernakalant
Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Mixtures name: … Aminosyn II 7% Injection ... Aminosyn II 7% With 50% Dextrose ... Aminosyn II 7% With 10% Dextrose …
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Iupac: … N-tert-butyl-4a,6a-dimethyl-2-oxo-1H,2H,4aH,4bH,5H,6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinoline-7- …
Matched Mixtures name: … Finasteride 0.1% / Minoxidil 7% ... Finasteride 0.1% / Minoxidil 7% / Tretinoin 0.025% …
Matched Mixtures name: … Finasteride 0.1% / Minoxidil 7% ... Finasteride 0.1% / Minoxidil 7% / Tretinoin 0.025% …
Misoprostol
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Iupac: … methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate …
Matched Mixtures name: … Arthrotec 75 ... ARTHROTEC 75 MG 10 TABLET ... Gd-diclofenac/misoprostol 75 …
Matched Mixtures name: … Arthrotec 75 ... ARTHROTEC 75 MG 10 TABLET ... Gd-diclofenac/misoprostol 75 …
Trazodone
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Products: … Trittico retard 75 mg - Tabletten …
Tetracaine
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Mixtures name: … Lidocaine 7% / Tetracaine 7% ... Lidocaine 23% / Tetracaine 7% ... Lidocaine 23% / Tetracaine 7% …
Latamoxef
Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Approved
Investigational
Matched Iupac: … (6R,7R)-7-[2-carboxy-2-(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl …
Tioconazole
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Salts cas: … 61675-64-7 …
Matched Mixtures name: … GYNOMAX L VAJINAL OVUL, 7 ADET ... GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADET …
Matched Mixtures name: … GYNOMAX L VAJINAL OVUL, 7 ADET ... GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADET …
Methocarbamol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Lanthanum carbonate
Lanthanum carbonate is a phosphate binder commonly used in clinical practice. It is marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is the largest of all pills filled in community pharmacies. Sometimes patients forget that Fosrenol is not swallowed whole, but instead should be chewed. This has led...
Approved
Naldemedine
Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton …
Ulmus americana pollen
Ulmus americana pollen is the pollen of the Ulmus americana plant. Ulmus americana pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Eastern 7 Tree Pollen Mix ... Eastern 7 Tree Pollen Mix ... Eastern 7 Tree Pollen Mix …
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Salts cas: … 1070-11-7 …
Matched Mixtures name: … RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG ... RIFAMPICINA 150 MG+ ISONIAZIDA 75 MG + PIRAZINAMIDA 400 MG+ ETAMBUTOL CLORHIDRATO 275 MG TABLETAS RECUBIERTAS …
Matched Mixtures name: … RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG ... RIFAMPICINA 150 MG+ ISONIAZIDA 75 MG + PIRAZINAMIDA 400 MG+ ETAMBUTOL CLORHIDRATO 275 MG TABLETAS RECUBIERTAS …
Halazepam
Halazepam is a benzodiazepine derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam. This drug is no longer marketed in the United States, and was withdrawn by Schering, its manufacturer, in 2009.[L6226, L6229]
Approved
Illicit
Withdrawn
Matched Iupac: … 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009 …
Matched Description: … drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009 …
Taliglucerase alfa
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Mixtures name: … RIFAMPICIN 75 MG / ISONIAZID 50 MG ... RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK) ... RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG …
Melphalan flufenamide
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Withdrawn
Matched Salts cas: … 380449-54-7 …
Calcium glubionate anhydrous
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Approved
Oxytocin
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Mixtures name: … Bakumokon 7% Minoxidil Sulfate …
Potassium chloride
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... SUERO ORAL 75 ... SUERO ORAL 75® …
Matched Products: … POTASYUM KLORUR 75 MG /1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL ... POTASYUM KLORUR 75 MG /1 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL …
Matched Products: … POTASYUM KLORUR 75 MG /1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL ... POTASYUM KLORUR 75 MG /1 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL …
Reviparin
Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … [A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Description: … According to the European Union Cosmetics Regulation (EC) n.1223/2009, phenoxyethanol is authorized as …
Matched Mixtures name: … 75% Alcohol Wipes ... Purgerm 75% alcohol wipes ... Purgerm 75% alcohol wipes …
Matched Mixtures name: … 75% Alcohol Wipes ... Purgerm 75% alcohol wipes ... Purgerm 75% alcohol wipes …
Displaying drugs 101 - 125 of 2923 in total