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Displaying drugs 151 - 175 of 13236 in total

Zanamivir

A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … (2R,3R,4S)-3-(acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran- ... 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid ... 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid …
Matched Iupac: … (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen

Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains* N. meningitis* serogroup y capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active ... The vaccine contains* N. meningitis* serogroup y capsular polysaccharide antigens that are purified and …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Synonyms: … Coagulation factor IX (recombinant), albumin fusion protein ... Coagulation Factor IX (Recombinant), Albumin Fusion Protein (rIX-FP) …
Matched Description: … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation ... factor IX (rFIX) with a recombinant human albumin (rAlbumin). …
Matched Categories: … Recombinant Proteins …

Interferon gamma-1b

Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography. The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b ... Interferon gamma-1b, recombinant …
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …

Interferon alfa-2a

Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched International brands: … Roferon A …
Matched Synonyms: … Interferon alfa-2a,recombinant ... Interferon alfa-2a, recombinant ... Interferon alfa-2a (recombinant) …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Products: … ROFERON-A 3 MIU IU ENEJKSİYONA HAZIR ŞIRINGA, 1 ADET ... Roferon-A Solution 3 Million I.U./ml ... ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml …

Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Synonyms: … Influenza B virus B/Austria/1359417/2021 live …
Matched Name: … Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen …
Matched Description: … of the virus) which results in an immunological defense against future exposure to the virus, or "antigen ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Live Attenuated Influenza B Virus Vaccine ... Influenza Vaccines …

Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta 1b (recombinant) ... Interferon beta-1b,recombinant ... Recombinant interferon beta-1b …
Matched Categories: … Recombinant Human Interferon beta …

Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen

Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an ... The vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified …

Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Synonyms: … Somatropin recombinant ... Recombinant human growth hormone ... Somatropin (recombinant DNA origin) …
Matched Description: … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone ... [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults ... of recombinant HGH. …
Matched Categories: … Recombinant Human Growth Hormone …
Matched Products: … GROWTROPINAQ 16 U /2 ML INYECTABLE ... POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... SciTropin A Solution for Injection 5 mg/1.5 ml …

Cyclosporine

Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Synonyms: … Cyclosporin A …
Matched Iupac: … (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28 ... -nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan …
Matched Description: … Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … Cyclosporine A ... Nail Cyclosporin-A ... MODUSIK-A OFTENO …

Vonicog alfa

Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor (recombinant) ... Von willebrand factor, recombinant, human …
Matched Description: … Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. …

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... Interleukin-2(2-133),125-ser …
Matched Description: … glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not ... Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E …
Matched Products: … PROLEUKIN 18X106 IU/ML STERİL IV LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …

Loncastuximab tesirine

Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... lymphoma is based on promising results from the LOTIS-2 clinical trial. ... This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Efanesoctocog alfa

Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl …
Matched Description: … Endogenous VWF protects FVIII from degradation but also sets a half-life of approximately 15 to 19 h. ... Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... designed to have an extended half-life, and to surpass the half-life ceiling to which other forms of recombinant …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched International brands: … Act-3 …
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... was in 1960 while researching for a safer alternative for aspirin. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Salts cas: … 79261-49-7 …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... 50 Person ANSI …
Matched Categories: … COX-1 Inhibitors ... COX-2 Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … PADUCAS 20 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 3 ADET ... DUKTAFEN 20 MG/2 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 3 ADET ... DISMENOL N …

Isotretinoin

Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … Neovitamin A acid ... 13-cis-Vitamin A acid …
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. ... [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574] …
Matched Mixtures name: … ETREXİN % 2 + % 0.05 JEL …

Mecasermin rinfabate

Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 ... rhIGF-I/rhIGFBP-3 ... Mecasermin rinfabate recombinant …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... growth factor 1 (IGF-1). ... protein 3 (IGFBP-3)[A12605]. …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine ... 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine …
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased …
Matched Mixtures name: … GLICERTOX N F ... BRONCODEX JARABE (GUAIFENESIN 2 G + BROMHEXINA HCI 0.08 G) …
Matched Products: … MUCOLIN 1% SOLUTION ... DEXHEXINE 2% W/W WATER SOLUBLE POWDER ... VISCOL TABLET, 50 ADET …

Alteplase

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Alteplase,recombinant ... Alteplase, recombinant ... Tissue plasminogen activator, recombinant …
Matched Description: … Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. ... [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster …
Matched Products: … ACTILYSE 50 MG FLAKON, 1 ADET ... Actilyse Cathflo 2 mg - Pulver zur Herstellung einer Injektionslösung ... ACTILYSE TREATMENT-SET 50 mg/vial …

Tofersen

Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … -METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP- ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene ... DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 …
Matched Description: … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more ... Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 …

Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …

Dornase alfa

Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) ... Dornase alfa, recombinant ... Recombinant deoxyribonuclease (DNAse) …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Synonyms: … Recombinant urate oxidase …
Matched Description: … Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces ... The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Matched Categories: … Recombinant Proteins …
Matched Products: … FASTURTEC 1,5 MG/1 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glargine recombinant …
Matched Description: … 1 and Type 2 Diabetes. ... [L34964] Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory ... with glycine and addition of two arginines to the C-terminus (positions B31 and 32) of the B-chain. …
Matched Mixtures name: … SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEM ... โซลิควา (100 ยูนิต/มิลลิลิตร + 50 ไมโครกรัม/มิลลิลิตร) ... SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEM …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... TOUJEO 300 U/ML SOLOSTAR SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKSİYON KALEMİ, 3 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Displaying drugs 151 - 175 of 13236 in total