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Displaying drugs 1 - 25 of 9103 in total
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1,8-dihydroxy-9,10-anthracenedione ... 1,8-dihydroxy-9,10-anthraquinone ... 1,8-dihydroxyanthra-9,10-quinone …
Matched Iupac: … 1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione …
4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this compound may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 4-Anilino-N-isopropylaniline …
Matched Name: … 4-(Isopropylamino)diphenylamine …
Matched Description: … 4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant …
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 9,10-dihydroergotamine ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraene-4-carboxamide ... 5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman …
Matched Iupac: … -4-carboxamide ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 ... }]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … technology developed by Impel Neuropharma technology has correlated with an increase of 3-fold in Cmax and 4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Products: … Migranal 4 mg/ml - Nasalspray …
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Synonyms: … Adenovirus Type 4 Vaccine Live ... Adenovirus Type 4 Strain Cl-68578 ... Adenovirus Vaccine, Live, Oral, Type 4
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 4 Vaccine …
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Approved
Investigational
Matched Synonyms: … N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea …
Matched Iupac: … diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl ... 9,10-didehydro-N-(α-(hydroxymethyl)ethyl)-6-methylergoline-8-β-carboxamide ... 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8β(S)-carboxamide …
Matched Iupac: … hydroxypropan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Approved
Matched Name: … Cyd dengue virus serotype 4 live (attenuated) antigen …
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … (3α,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid …
Matched Iupac: … (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid ... (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Salts cas: … 134606-40-9
Matched Mixtures name: … BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADET ... OSVIPAC 70 MG+1000 MG/880 IU TEDAVI PAKETI, 4+24 ADET ... OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET …
Matched Products: … Alendronate-10 ... ALENDRONATO 10 MG ... LENDO 10 MG TABLET, 28 ADET …
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-(4'-Nitrophenyl)-beta-acetylethyl)-4-hydroxycoumarin ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Categories: … 4-Hydroxycoumarins …
Matched Products: … Sintrom 4 mg Tabletten …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid …
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid …
Matched Mixtures name: … Allegra-D 24 Hour ... Allegra--D 24 Hour ... Allegra--D 24 Hour …
Matched Products: … 24 Hour Allergy ... Allergy 24-HR ... Allegra 24 Hour …
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-hydroxy-4-androstene-3,17-dione ... 4-Hydroxy-delta(4)-androstenedione ... 4-OH-A …
Matched Description: … Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity …
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … 4-isobutylhydratropic acid ... 2-(4-isobutylphenyl)propanoic acid ... α-(4-isobutylphenyl)propionic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development …
Matched Salts cas: … 57469-77-9
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Adventure Medical Kits 1-4 Person First Aid ... Xylon 10
Matched Products: … CORELAR 10 MG/2 ML IV İNFÜZYONLUK ÇÖZELTİ, 4 ADET ... PATENTOFEN 10 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 4 ADET ... İBUPROFEN-PF 400 MG/4 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 10 ADET …
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, and 4; …
Matched Products: … เล็นวิมา (4 มิลลิกรัม) ... เล็นวิมา (10 มิลลิกรัม) ... Lenvima 4 mg Hard Capsules …
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol ... 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... Etrafon 2 10 ... PMS-levazine 4/25 Tab …
Matched Products: … เปอร์-4 ... โมนาซีน-4 ... โปราซิน 4
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-.DELTA. …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … ITRACONAZOL 10 MG/ ML ... FUNİT 100 MG KAPSÜL, 4 ADET ... SPORANOX ORAL SOLUTION 10 mg/ml …
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Synonyms: … 4-(Benzyloxy)phenol ... 4-Benzyloxyphenol ... 4-Benzyloxy-phenol …
Matched Iupac: … 4-(benzyloxy)phenol …
Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. First approved by the FDA on September 15, 2023, momelotinib is used to treat myelofibrosis. Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells,...
Approved
Investigational
Matched Synonyms: … N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE …
Matched Iupac: … N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide …
Matched Salts cas: … 1841094-17-4
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 4-(4-Biphenylyl)-4-oxobutyric acid ... 3-(4-Phenylbenzoyl)propionic acid ... 3-(4-Biphenylylcarbonyl)propionic acid …
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine ... 4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide ... 2-Sulfa-4-methylpyrimidine …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … -4-methylpiperazine ... 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Products: … RETOMİN 10 MG/ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 112 ML ... VEGIRO 100 MG FILM TABLET,4 ADET ... DEGRA 25 MG FILM TABLET, 4 ADET …
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Synonyms: … 4-(2-aminoethyl)catechol ... 4-(2-aminoethyl)pyrocatechol ... 4-(2-aminoethyl)-1,2-benzenediol …
Matched Iupac: … 4-(2-aminoethyl)benzene-1,2-diol …
Matched Products: … Dopamine HCl Inj 4% ... ./10มล.) ... DOPAMIN FRESENIUS 10 AMPUL …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
Matched Products: … METHOTREXAT 'EBEWE' PFS 10 MG/1 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET ... METHOTREXAT 'EBEWE' PFS 20 MG/2 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET ... METHOTREXAT 'EBEWE' PFS 15 MG/1,5 ML KULLANIMA HAZIR ENJEKTÖR, 4 ADET …
A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a...
Approved
Vet approved
Matched Synonyms: … 1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one ... 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl}-2,3-dihydro-1H-benzo[d]imidazol- ... 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone …
Matched Iupac: … 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2 …
Displaying drugs 1 - 25 of 9103 in total