Displaying drugs 51 - 75 of 4338 in total
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … form is isolated from pooled human plasma. ... When supplied as the recombinant form, Coagulation Factor XIII A-Subunit (Recombinant) binds to free human ... Coagulation Factor XIII A-Subunit (Recombinant) include [DB12909], which is a purified endogenous (human …
Matched Description: … form is isolated from pooled human plasma. ... When supplied as the recombinant form, Coagulation Factor XIII A-Subunit (Recombinant) binds to free human ... Coagulation Factor XIII A-Subunit (Recombinant) include [DB12909], which is a purified endogenous (human …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Recombinant human interferon alfa-2a ... Recombinant human interferon-alfa-2a …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). …
Coagulation Factor IX (Recombinant)
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human …
Matched Description: … engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell medium ... It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Description: … engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell medium ... It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … Follitropin beta is produced in genetically engineered Chinese hamster cell lines (CHO). ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed …
Matched Description: … Follitropin beta is produced in genetically engineered Chinese hamster cell lines (CHO). ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... The nomenclature “beta” differentiates it from another recombinant human FSH product that was marketed …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … ) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JNJ-63483043 .LAMBDA ... IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional ... is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell ... [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional ... is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell ... [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma …
Insulin lispro
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin,lispro,human/rDNA …
Matched Description: … is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human ... Formerly called LYSPRO from the chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human …
Matched Description: … is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human ... Formerly called LYSPRO from the chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … The localized expression of this gene induces anti-tumor effects. ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Matched Description: … The localized expression of this gene induces anti-tumor effects. ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Allantoin
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … human diets [FDA Label]. ... In human muscle, urate is oxidized to allantoin during such exercise [FDA Label]. ... In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. …
Matched Mixtures name: … Breast Essence II ... Inner Cell Serum- Serum ... Cell Power Boosting Essence …
Matched Products: … Luxury Cell Performance Serum ... Luxury Cell Performance Toner ... Ruby Cell 4u Carbonated Mist …
Matched Mixtures name: … Breast Essence II ... Inner Cell Serum- Serum ... Cell Power Boosting Essence …
Matched Products: … Luxury Cell Performance Serum ... Luxury Cell Performance Toner ... Ruby Cell 4u Carbonated Mist …
Butylene glycol
Approved
Experimental
Matched Products: … SiYi Human Body Lubricant ... Human Body Lubricant R170009 …
Temozolomide
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Products: … TEMOZO CELL 5 MG HKP ... TEMOZO CELL 20 MG HKP ... TEMOZO CELL 100 MG HKP …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Mixtures name: … Breast Essence III ... Subuni Breast Pack ... Stem Cell Hmsc Cell Rejuvenation-ampoule …
Matched Products: … Stem Cell Renew ... Stem Cell Wrinkle Serum ... Drh T Stem Cell …
Matched Products: … Stem Cell Renew ... Stem Cell Wrinkle Serum ... Drh T Stem Cell …
Letrozole
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Products: … LETRO CELL 2.5 MG …
Sea salt
Sea salt is the salt obtained from the evaporation of seawater or water from saltwater lakes. Sea salt production is subject to little processing which leaves certain trace minerals and elements behind. In comparison, table salt is mined from underground sedimentary deposits and is more heavily processed to eliminate minerals....
Approved
Matched Products: … Ruby Cell 4u Mud Moisture Pure …
Fluorouracil
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Products: … 5-FU CELL 50MG/ML ILO 1000 ... 5-FU CELL 50MG/ML ILO 5000 …
Epirubicin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Elacestrant
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Description: … approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast ... therefore, the use of a SERD represents a therapeutic approach for the treatment of endocrine-resistant breast …
Tucatinib
Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Description: … with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast ... [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not …
Matched Categories: … Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors …
Matched Categories: … Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors …
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast ... hypersensitivity reactions, fluid retention, second primary malignancies, embryo-fetal toxicity, and tumor ... division and promote to cell death. …
Encorafenib
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Description: … lung carcinoma, hairy cell leukemia and adenocarcinoma of the lung. ... L12216] This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell ... other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell …
Displaying drugs 51 - 75 of 4338 in total