Displaying drugs 876 - 900 of 992 in total
2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate
Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... as amitriptyline and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Desipramine Hydrochloride …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Desipramine Hydrochloride …
Fusidic acid
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Products: … Fucidin Leo Sus 246mg/5ml …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Products: … Fucidin Leo Sus 246mg/5ml …
Phenol
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL ... Bite and Sting Relief Stick …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … , OILY PHENOL INJECTION 250MG/5ML ... Good Sense Sore Throat ... Smart Sense Sore Throat …
Matched Mixtures name: … Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL ... Bite and Sting Relief Stick …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … , OILY PHENOL INJECTION 250MG/5ML ... Good Sense Sore Throat ... Smart Sense Sore Throat …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … reducing the reinforcing effects of opioids which can lead to drug-seeking behaviours. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... who require larger and more frequent doses. …
Matched Mixtures name: … Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Buprenorphine hydrochloride …
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …
Matched Mixtures name: … Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Buprenorphine hydrochloride …
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …
5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Experimental
Matched Name: … 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior ... abuse, and can significantly impact the quality of life of patients and caregivers. ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …
Anagrelide
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Description: … [busulfan], [hydroxyurea]) and may be better tolerated.[A214274] …
Matched Salts name: … Anagrelide hydrochloride ... Anagrelide hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Anagrelide Hydrochloride …
Matched Salts name: … Anagrelide hydrochloride ... Anagrelide hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Anagrelide Hydrochloride …
Fluoxetine
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Fluoxetine hydrochloride …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... Fluoxetine Hydrochloride ... Fluoxetine hydrochloride …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Fluoxetine hydrochloride …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... Fluoxetine Hydrochloride ... Fluoxetine hydrochloride …
Citicoline
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … SENTAX …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … SENTAX …
Carbinoxamine
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and...
Approved
Matched Synonyms: … 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid …
Methyldopa
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug ... alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Salts name: … Methyldopa hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Methyldopate Hydrochloride …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Salts name: … Methyldopa hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Methyldopate Hydrochloride …
3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE
Experimental
Matched Name: … 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Fingolimod
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … neurological, physical, and cognitive effects. ... Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe ... It was developed by Novartis and initially approved by the FDA in 2010. …
Matched Salts name: … Fingolimod hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Fingolimod Hydrochloride …
Matched Salts name: … Fingolimod hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Fingolimod Hydrochloride …
3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)))
Investigational
Matched Synonyms: … 3-(4-(1,5-napthrydine)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin ... rabeprazole, amoxicillin and metronidazole …
Matched Products: … Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml ... Amox S 250 Sus 250mg/5ml …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin ... rabeprazole, amoxicillin and metronidazole …
Matched Products: … Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml ... Amox S 250 Sus 250mg/5ml …
Cavrotolimod
Investigational
Matched Synonyms: … -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53 …
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas …
Matched Mixtures name: … Gelusil Antacid and Anti-gas …
Matched Categories: … Silicones ... Silicon Compounds …
Matched Products: … VELGASTIN BLAEHUNGEN SUS …
Matched Mixtures name: … Gelusil Antacid and Anti-gas …
Matched Categories: … Silicones ... Silicon Compounds …
Matched Products: … VELGASTIN BLAEHUNGEN SUS …
3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine
Experimental
Matched Name: … 3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine …
Matched Iupac: … 3-[(3-methoxyphenyl)methyl]-1H-pyrrolo[2,3-b]pyridine …
Matched Iupac: … 3-[(3-methoxyphenyl)methyl]-1H-pyrrolo[2,3-b]pyridine …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are …
Matched Salts name: … Nebivolol hydrochloride …
Matched Categories: … Beta Blocking Agents and Thiazides ... valsartan and nebivolol ... nebivolol and thiazides ... nebivolol and amlodipine ... Beta blocking agents and calcium channel blockers …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride …
Matched Salts name: … Nebivolol hydrochloride …
Matched Categories: … Beta Blocking Agents and Thiazides ... valsartan and nebivolol ... nebivolol and thiazides ... nebivolol and amlodipine ... Beta blocking agents and calcium channel blockers …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride …
2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE
Experimental
Matched Name: … 2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE …
6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
Experimental
Matched Name: … 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE …
3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
Displaying drugs 876 - 900 of 992 in total