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Displaying drugs 76 - 100 of 13643 in total
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … Neovitamin A acid ... 13-cis-Vitamin A acid …
Matched Description: … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. ... the iPLEDGE program in the United States. ... [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under …
Matched Categories: … Retinoids for Topical Use in Acne ... Retinoids for Treatment of Acne ... Anti-Acne Preparations for Systemic Use ... Anti-Acne Preparations for Topical Use …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … (T,G)-A-L …
Matched Description: … [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. ... first-line drug for patients with MS. ... [A248870] Originally, glatiramer acetate was designed as a stimulant of myelin basic protein (MBP), a
Matched Products: … Copaxone 20 mg/ml Injektionslösung in einer Fertigspritze ... Copaxone 40 mg/ml Injektionslösung in einer Fertigspritze ... Copaxobene 20 mg/ml Injektionslösung in einer Fertigspritze …
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-OH-A
Matched Iupac: … 9bS,11aS)-6-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity ... Currently, formestane (categorized as an anti-estrogenic agent) is prohibited from use in sports in accordance …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Factor XIII A-Subunit (Recombinant) ... Coagulation Factor XIII A-Subunit (recombinant) ... Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous ... for the routine prophylaxis of bleeding. ... human FXIII B-subunit resulting in a heterotetramer (rA2B2) with a similar activity profile and half-life …
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … FSH-a
Matched Description: … with significantly higher estradiol (E2) levels. ... Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for ... However, a more recent study showed there is may be a slight clinical difference, with the alpha form …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... MENOGON 75 IU Powder and Solvent for solution for Injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Products: … REKOVELLE SOLUTION FOR INJECTION IN A PRE-FILLED PEN 12MCG/0.36ML ... REKOVELLE SOLUTION FOR INJECTION IN A PRE-FILLED PEN 72MCG/2.16ML ... REKOVELLE SOLUTION FOR INJECTION IN A PRE-FILLED PEN 36MCG/1.08ML …
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … to lower glucose levels in the blood. ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type ... a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL ... LANTUS 100 Units/ml Solution for injection in a vial ... LANTUS SOLOSTAR 100IU/ML SOLUTION FOR INJECTION IN A PRE-FILLED PEN …
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Synonyms: … 6-O-methylerythromycin A
Matched Description: … Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … KLACID GRANULES FOR ORAL SUSPENSION ... MACROMYCIN GRÁNULOS PARA RECONSTITUIR A SUSPENSIÓN ORAL ... KLACID IV FOR INJECTION 500 mg/vial …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … It is a major metabolic intermediate in most organisms. ... The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of …
Matched Mixtures name: … Mycellcare All in One Serum ... Infinite Aloe All-IN-one Skin Care ... QYO QYO Tangerine Bright Moist All In One Cream …
Matched Products: … ZAREE All Kii Coconut Water ... ATOMU Essence A ... Atomu Essence A
Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramcidins are 15 residue peptides with alternating D and L amino...
Approved
Matched Synonyms: … Gramicidin A
Matched Description: … topical antibiotic and is also found in Polysporin ophthalmic solution. ... up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis ... Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making …
Matched Mixtures name: … Polysporin for Kids ... Antibiotic Cream for Kids ... Polysporin for Stitches …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP …
Matched Description: … A259033] Tofersen was granted accelerated approval from the FDA on April 25, 2023, as the first treatment for ... [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... light chains in plasma over 28 weeks, although the ALS Functional Rating Scale–Revised did not improve …
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. FDA approved on...
Approved
Investigational
Nutraceutical
Matched Synonyms: … all-cis-ethyl 5,8,11,14,17-icosapentaenoate ... Ethyl all-cis-5,8,11,14,17-icosapentaenoate ... Ethyl (all cis)-5,8,11,14,17-icosapentaenoate …
Matched Description: … It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce ... the risk of cardiovascular events in certain patients with elevated triglycerides. ... Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic …
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705] ... Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … all-cis-DHA ... all-cis-4,7,10,13,16,19-docosahexaenoic acid …
Matched Description: … structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in ... A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. …
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Description: … Zinc oxide is an inorganic compound used in a number of manufacturing processes. ... It is also widely used to treat a variety of other skin conditions, in products such as baby powder and ... It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives …
Matched Mixtures name: … Super BB All-In-1 ... Yay Novelty All-IN-one ... COVERQUEEN All in one sun roll …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … In Your Face Mineral Tint SPF 31 ... 5-IN-1 Tinted Face Sunscreen - Fair ... 5-IN-1 Tinted Face Sunscreen - Light …
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … -(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a] …
Matched Iupac: … -(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a] …
Matched Description: … Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs ... [A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark ... including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and [vandetanib], have shown efficacy in
Meningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup W-135. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.
Approved
Experimental
Investigational
Matched Synonyms: … Neisseria meningitidis group W-135 polysaccharide antigen, A
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia …
Matched Mixtures name: … Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … not described in literature until the 1940s. ... The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were ... [A229833,A229838] Adenosine is also indicated in the treatment of supraventricular tachycardia. …
Matched Mixtures name: … Too im Cell ALL IN ONE ... COVERQUEEN All in one sun roll ... Volcanic Homme All in One Essence …
Matched Products: … Jdew Homme All for You Aqua Marine All In One ... Advanced Snail 92 All in One Cream ... Mizon All In One Snail Repair Crea M …
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... Zylonta also received approval in the EU on December 22, 2022. ... [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched International brands: … Roferon A
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... Interferon a (human leukocyte protein moiety reduced). …
Matched Products: … ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml ... Roferon-A ... ROFERON A
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Iupac: … 1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine …
Matched Description: … It is found in ophthalmic solutions used to reverse mydriasis after an eye examination. …
Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Description: … Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in ... Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. …
Matched Mixtures name: … COMBIVENT UNIT DOSE VIAL FOR INHALATION ... Combivent nebuliser solution in unit dose vial ... Combivent Lösung für einen Vernebler in Einzeldosisbehältnissen …
Matched Categories: … Drugs for Obstructive Airway Diseases ... Medications that reduce magnesium levels
Matched Products: … Injection 0.5mg Salbutamol In 1 Ml (500mcg/ml) ... VENTOLIN SOLUTION FOR IV INFUSION 1MG/ML ... Bolus Injection 0.25mg Salbutamol In 5ml (50mcg/ml) …
Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection ... The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium ... It is used for active immunization of children 7 years of age or older, and adults, for prevention of …
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … TETAVAX single dose, suspension for injection in a prefilled syringe …
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … They are approved for all eligible indications of the reference product. ... In clinical trials, multiple infusions of infliximab displayed in a reduction of signs and symptoms of ... Inflectra, a first biosimilar drug product, was approved in 2016. …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED PEN ... REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED SYRINGE ... Remsima Powder for Concentrate for Solution for Infusion …
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … a-Ketopropionic acid …
Matched Description: … In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous ... An intermediate compound in the metabolism of carbohydrates, proteins, and fats. …
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … as food processing and cooking vegetables (which are normally a rich source of magnesium). ... [A32810] Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein ... [A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite …
Matched Mixtures name: … For-2 ... Doctor's Choice Brand for Men ... One A Day Tab …
Matched Products: … MAGNEROT A 500 BEUTEL ... MAGNEROT A 120 KAUTABL ... Port A Mins Super Magnesium 188 …
Displaying drugs 76 - 100 of 13643 in total