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Displaying drugs 76 - 100 of 265 in total

Loteprednol etabonate

Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, it can...
Approved
Matched Description: … As a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. ... , uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and ... prescription LE products, however, tend to be indicated for the treatment of post-operative inflammation and …

Ipratropium

Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Salts name: … Ipratropium chloride …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide …

Beclomethasone dipropionate

Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... formoterol, glycopyrronium bromide and beclometasone …

Selumetinib

Activation of the Raf-MEK-ERK signalling pathway is known to be implemented in several types of malignancies; thus, mitogen-activated protein kinase kinase (MEK) inhibitors such as selumetinib are important tools that can target the problematic overactivity of this pathway. Results from clinical trials investigating earlier developed MEK inhibitors were underwhelming. However,...
Approved
Investigational
Matched Description: … [A193611] However, selumetinib demonstrated impressive efficacy and tolerability in Phase I trials, leading ... Luckily, the use of selumetinib in patients with NF-1 have shown efficacy in shrinking associated tumours and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Chloramphenicol palmitate

Approved
Vet approved

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially …

Elvitegravir

Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the...
Approved
Matched Description: … Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. ... thereby blocks the formation of the HIV-1 provirus and resulting propagation of the viral infection. ... necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and …
Matched Categories: … emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat …

Isavuconazonium

Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Description: … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and ... Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July ... 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed …
Matched Categories: … Isavuconazole and Prodrugs …

Pimecrolimus

Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Approved
Investigational
Matched Categories: … Skin and Mucous Membrane Agents …

Ganirelix

Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Choline C 11

Choline C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes. It was developed by MCPRF and FDA first approved in September 2012.
Approved
Investigational
Matched Synonyms: … 11C-choline chloride …
Matched Iupac: … (2-hydroxyethyl)((¹¹C)methyl)dimethylazanium chloride …
Matched Description: … [A32041] It was developed by MCPRF and FDA first approved in September 2012. …

Etafedrine

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued . Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … The hydrochloride is be prepared by passing hydrogen chloride through a solution of ethylephedrine in ... with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined …

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Description: … Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride ... Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase ... This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal …
Matched Mixtures name: … Benzalkonium Chloride and Lidocaine Hydrochloride ... Benzalkonium Chloride and Lidocaine Hydrochloride ... Alcohol Wipes …
Matched Salts name: … Benzalkonium chloride …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Sanitizer and Re-Moisturizer with Benzalkonium Chloride ... KUNDAL PURE and SAFE SANITIZING TISSUE (BENZALKONIUM CHLORIDE) ... KUNDAL PURE and SAFE SANITIZING WIPE PLUS (BENZALKONIUM CHLORIDE) …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1 ... It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). …
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …
Matched Salts name: … Benzethonium chloride …
Matched Categories: … Antiseptics and Disinfectants ... benzethonium chloride ... benzethonium chloride, combinations …
Matched Products: … Piranha Brand Alcohol Free Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Benzethonium Chloride ... Benzethonium Chloride Solution …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Menthol

Approved
Matched Mixtures name: … Orajel 2x Gum Pain Alcohol-Free ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Products: … Throat and Chest Chili and Lime ... Up and Up Hot and Cold Medicated ... Muscle and Joint …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. …
Matched Mixtures name: … Alcohol 5% and Dextrose 5% Inj USP ... Alcohol 5% and Dextrose 5% Injection USP ... Potassium Chloride in Dextrose and Sodium Chloride …

Clorazepic acid

Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.[A957,L44788] Following administration, clorazepate is rapidly converted to nordiazepam (N-desmethyldiazepam), its active metabolite, before entering systemic circulation. Similar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA)...
Approved
Illicit
Matched Description: … depression, coma, and death. ... Also, the use of clorazepate exposes users to users to the risks of abuse, misuse, and addiction, and ... Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …

Sodium ascorbate

Approved
Nutraceutical
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Vitamin C and analogues ... Diet, Food, and Nutrition …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. ... and the nervous and digestive systems. ... It is essential for normal growth and development and helps to maintain proper functioning of the heart …
Matched Mixtures name: … Somarexin and C 1000 ... Multi Vitamin and Mineral vitamin ... Multi Vitamin and Fluoride …
Matched Salts name: … Thiamine chloride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …

Lactic acid

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … Potassium Chloride and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Chloral hydrate

A hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as an anti-anxiety medication.
Approved
Illicit
Investigational
Vet approved
Matched Description: … A hypnotic and sedative used in the treatment of insomnia. …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …

Hydroxychloroquine

Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and ... [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Eszopiclone

Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Description: … [A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a …
Matched Categories: … Hypnotics and Sedatives ... Zopiclone and prodrugs ... Benzodiazepine hypnotics and sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... cerebrospinal fluid, into interstitial fluid and plasma. …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Blood Substitutes and Perfusion Solutions …
Displaying drugs 76 - 100 of 265 in total