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Displaying drugs 1 - 25 of 41 in total
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Synonyms: … Ioxaglic acid …
Matched Name: … Ioxaglic acid …
Matched Iupac: … triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido)phenyl]formamido}acetamido)benzoic acid …
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast ... Ioxaglic acid is marketed as Hexabrix. …
Matched Categories: … ioxaglic acid …
Matched Name: … Ioxaglic acid …
Matched Iupac: … triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido)phenyl]formamido}acetamido)benzoic acid …
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast ... Ioxaglic acid is marketed as Hexabrix. …
Matched Categories: … ioxaglic acid …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Synonyms: … Iotalamic acid ... Iothalamic acid …
Matched Name: … Iothalamic acid …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Matched Description: … Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent. …
Matched Categories: … iotalamic acid …
Matched Name: … Iothalamic acid …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Matched Description: … Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent. …
Matched Categories: … iotalamic acid …
Tyropanoic acid
Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones, which results in a visible image .
Approved
Matched Name: … Tyropanoic acid …
Matched Iupac: … 2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. ... Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones ... The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in …
Matched Categories: … tyropanoic acid …
Matched Iupac: … 2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. ... Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones ... The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in …
Matched Categories: … tyropanoic acid …
Potassium perchlorate
Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags . The use of potassium perchlorate as a component in sealing gaskets for food containers...
Approved
Investigational
Matched Synonyms: … Perchloric acid, potassium salt …
Matched Description: … Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates ... Potassium is most commonly used in flares and automobile airbags [A32609]. ... perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and …
Matched Categories: … Sex Hormones and Insulins …
Matched Description: … Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates ... Potassium is most commonly used in flares and automobile airbags [A32609]. ... perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and …
Matched Categories: … Sex Hormones and Insulins …
Iobenguane
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. ... The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that ... Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. …
Matched Categories: … Indicators and Reagents ... Iodine (131I) Compounds …
Matched Categories: … Indicators and Reagents ... Iodine (131I) Compounds …
Thyrotropin alfa
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one ... similarity with the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and ... The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Iohexol
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. ... water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and …
Methimazole
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine ... [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Liotrix
Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Description: … and combination hormone replacement therapy generally offers no therapeutic advantage. ... It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in ... It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Carbimazole
An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Approved
Investigational
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Potassium
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … dextrose and sodium chloride. ... [A186928] Many conditions and diseases interfere with normal body potassium balance, and underconsumption ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … Potassium and Iodine Tab ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Revit Multi-vitamins and Minerals …
Matched Categories: … mefruside and potassium ... clopamide and potassium ... clofenamide and potassium ... furosemide and potassium ... quinethazone and potassium …
Matched Mixtures name: … Potassium and Iodine Tab ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Revit Multi-vitamins and Minerals …
Matched Categories: … mefruside and potassium ... clopamide and potassium ... clofenamide and potassium ... furosemide and potassium ... quinethazone and potassium …
Potassium chloride
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … in fertilizers and explosives. ... that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and ... crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and …
Matched Mixtures name: … Potassium and Iodine Tab ... Iodine-potassium Tablets ... Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Mixtures name: … Potassium and Iodine Tab ... Iodine-potassium Tablets ... Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Iopanoic acid
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Synonyms: … Iopanoic acid ... Iodopanoic acid …
Matched Name: … Iopanoic acid …
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … iopanoic acid …
Matched Name: … Iopanoic acid …
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … iopanoic acid …
Ioxilan
Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Approved
Isopropyl alcohol
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … Loris 10% Povidone-Iodine and 70% Isopropyl Alcohol Solution ... Loris 7.5% Povidone-Iodine and 74% Isopropyl Alcohol Solution ... Soluprep 10% Povidone Iodine + 70% Isopropyl Alcohol …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Clean Skin club Hydrating Hand Sanitizer with Aloe Vera and Hyaluronic Acid ... HUMCO 1 Percent Iodine ... Up and Up alcohol …
Matched Mixtures name: … Loris 10% Povidone-Iodine and 70% Isopropyl Alcohol Solution ... Loris 7.5% Povidone-Iodine and 74% Isopropyl Alcohol Solution ... Soluprep 10% Povidone Iodine + 70% Isopropyl Alcohol …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Clean Skin club Hydrating Hand Sanitizer with Aloe Vera and Hyaluronic Acid ... HUMCO 1 Percent Iodine ... Up and Up alcohol …
Iopromide
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including...
Approved
Matched Description: … [A260751] Although the mechanism is unclear, women and outpatients tend to have a higher incidence of ... several serious adverse effects, including cardiac events, thromboembolism, hypersensitivity reaction, and ... brain computer tomography (CT), coronary arteriography, left ventriculography, visceral angiography, and …
Liothyronine
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 ... the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 ... the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … in tumour cell proliferation and tumour angiogenesis. ... Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Lenvatinib
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Description: … indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine ... differentiation, and in pathogenic angiogenesis, lymphogenesis, tumour growth and cancer progression ... 4; the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Dronedarone
Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Description: … L8699]
Dronedarone is a related benzofuran compound to amiodarone but its chemical structure lacks iodine ... toxicities, such as thyroid and pulmonary toxicities. ... calcium ion channels and inhibiting β-adrenergic receptors. …
Povidone-iodine
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Synonyms: … Povidone iodine ... Povidone-iodine …
Matched Name: … Povidone-iodine …
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic ... Shelanski and M. V. Shelanski. …
Matched Mixtures name: … Loris 10% Povidone-Iodine and 70% Isopropyl Alcohol Solution ... Loris 7.5% Povidone-Iodine and 74% Isopropyl Alcohol Solution ... Persist Povidone Iodine Prep …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Iodine Products ... Iodine Compounds …
Matched Products: … PVP Iodine Prep Pad Medium and Large ... PVP Iodine Prep Swabstick Ones and Threes ... Fresh and Pure …
Matched Name: … Povidone-iodine …
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic ... Shelanski and M. V. Shelanski. …
Matched Mixtures name: … Loris 10% Povidone-Iodine and 70% Isopropyl Alcohol Solution ... Loris 7.5% Povidone-Iodine and 74% Isopropyl Alcohol Solution ... Persist Povidone Iodine Prep …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Iodine Products ... Iodine Compounds …
Matched Products: … PVP Iodine Prep Pad Medium and Large ... PVP Iodine Prep Swabstick Ones and Threes ... Fresh and Pure …
Iopodic acid
Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Name: … Iopodic acid …
Matched Iupac: … 3-(3-{[(dimethylamino)methylidene]amino}-2,4,6-triiodophenyl)propanoic acid …
Matched Description: … a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. ... Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by ... It was developed and filed to the FDA by the company BRACCO. …
Matched Iupac: … 3-(3-{[(dimethylamino)methylidene]amino}-2,4,6-triiodophenyl)propanoic acid …
Matched Description: … a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. ... Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by ... It was developed and filed to the FDA by the company BRACCO. …
Ioflupane I-123
Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Synonyms: … Iodine ioflupane (123I) …
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Categories: … Iodine Radioisotopes ... Iodine (123I) Compounds ... iodine ioflupane (123I) …
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Categories: … Iodine Radioisotopes ... Iodine (123I) Compounds ... iodine ioflupane (123I) …
Diatrizoate
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Synonyms: … Urografin acid ... Diatrizoic acid ... Methalamic acid …
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid …
Matched Description: … , and urography. ... As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoic acid dihydrate …
Matched Categories: … diatrizoic acid …
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid …
Matched Description: … , and urography. ... As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoic acid dihydrate …
Matched Categories: … diatrizoic acid …
Displaying drugs 1 - 25 of 41 in total