|DB00204||Dofetilide||For the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm|
|DB00285||Venlafaxine||For the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain.|
|DB00360||Sapropterin||For the treatment of tetrahydrobiopterin (BH4) deficiency.|
|DB00574||Fenfluramine||For the management of exogenous obesity as a short-term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction.|
|DB00661||Verapamil||For the treatment of hypertension, angina, and cluster headache prophylaxis.|
|DB00723||Methoxamine||Indicated for the treatment and management of hypotension.|
|DB00841||Dobutamine||For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures|
|DB00847||Cysteamine||Given intravenously or orally to treat radiation sickness. The bitartrate salts (Cystagon® and Procysbi) have been used for the oral treatment of nephropathic cystinosis and cystinurea. The hydrochloride salt (Cystaran™) is indicated for the treatment of corneal cystine crystal accumulation in cystinosis patients.
|DB00852||Pseudoephedrine||For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.|
|DB00865||Benzphetamine||For the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction|
|DB00867||Ritodrine||For the treatment and prophylaxis of premature labour|
|DB00925||Phenoxybenzamine||For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.|
|DB00937||Diethylpropion||Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.|
|DB00938||Salmeterol||For the treatment of asthma and chronic obstructive pulmonary disease (COPD).|
|DB00985||Dimenhydrinate||Dimenhydrinate is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.|
|DB01037||Selegiline||Monotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression.|
|DB01075||Diphenhydramine||Diphenhydramine is a first-generation histamine H1 receptor antagonist (H1 antihistamine) that is widely available as a non-prescription, over-the-counter (OTC) medication. As an OTC medication, diphenhydramine is typically formulated as tablets and creams indicated for use in treating sneezing, runny nose, itchy/watery eyes, itching of nose or throat, insomnia, pruritis, urticaria, insect bites/stings, allergic rashes, and nausea [L5263, L5266, L5269, F3379, A174541].
Additionally, when the use of oral diphenhydramine is impractical, there are also prescription-only formulations such as diphenhydramine injection products that are effective in adults and pediatric patients (other than premature infants and neonates) for:
i) the amelioration of allergic reactions to blood or plasma, in anaphylaxis as an adjunct to epinephrine and other standard measures after acute allergic reaction symptoms have been controlled, and for other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated [F3352];
ii) the active treatment of motion sickness [F3352]; and
iii) use in parkinsonism when oral therapy is impossible or contraindicated, as follows: parkinsonism in the elderly who are unable to tolerate more potent agents; mild cases of parkinsonism in other age groups, and in other cases of parkinsonism in combination with centrally acting anticholinergic agents [F3352].|
|DB01173||Orphenadrine||Indicated for the treatment of Parkinson's disease.|
|DB01191||Dexfenfluramine||For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet|
|DB01237||Bromodiphenhydramine||For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.|
|DB01255||Lisdexamfetamine||For the treatment of Attention-deficit/hyperactivity disorder (ADHD) and for moderate to severe binge eating disorder in adults [FDA label], [A40246].
This drug is not indicated for weight loss. Use of other sympathomimetic drugs for weight loss is associated with serious cardiovascular effects. The safety and effectiveness of this drug for the treatment of obesity have not yet been determined [FDA label].
|DB01364||Ephedrine||Ephedrine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia.|
|DB01365||Mephentermine||Used to maintain blood pressure in hypotensive states.|
|DB01442||MMDA||MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present.|
|DB01454||Midomafetamine||Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.|
|DB01550||Fenproporex||Fenproporex is used as an appetite suppressant, and anti-obesity agent ; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as Brazil, it is still prescribed -- often in the form of diet pills (ie. Brazilian Diet Pills) which combine amphetamines, benzodiazepines, antidepressants, diuretics and laxatives.
In the United States the sale of such diet pills has been banned due to concerns over side effects, and the risk of potentially fatal overdose.
However, internet sales and illicit markets has lead to international availability. It has been found by primary care physicians that Brazilian immigrant women utilized imported diet pills at particularly high rates, and sometimes suffered from side effects requiring hospitalization or experienced a loss of employment. |
|DB01556||Chlorphentermine||Used as an appetite suppressant.|
|DB01576||Dextroamphetamine||Used to treat attention deficit hyperactivity disorder (ADHD).|
|DB01577||Metamfetamine||For the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity.|
|DB05381||Histamine||Histamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function.|
|DB05800||Alethine||Investigated for use/treatment in blood (blood forming organ disorders, unspecified), lymphoma (unspecified), and multiple myeloma.|
|DB06152||Nylidrin||Nylidrin is mainly indicated in conditions like arteriosclerosis, cerebrovascular disease, peripheral vascular disease, Raynaud's disease, thrombo-angitis obliterans, and thrombophlebitis [L2285]. It may sometimes be used in the treatment of peripheral vascular disorders in addition premature labor (however, the drug is not approved for premature labor)[A32531].|
|DB09352||Hydroxyamphetamine||Mydriatic agent (eye pupil dilatation) for diagnosis of ophthalmic nerve lesions.|
|DB11587||Etafedrine||Conditions characterized by bronchial congestion and bronchospasm when an expectorant or bronchodilator action is required, such as acute bronchitis, acute episodes of chronic bronchitis and bronchial asthma [L2565], [L2566].|
|DB11610||Oxilofrine||Used in combination with [DB11609] as an antitussive [FDA Label].|
|DB13025||Tiapride||Tiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.|
|DB13139||Levosalbutamol||Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.|