Adrenergic beta-Agonists

Drugs that selectively bind to and activate beta-adrenergic receptors.
DrugDrug NameDrug Description
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00841DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
DB01064IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
DB00221IsoetarineFor the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
DB00816OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
DB00867RitodrineAn adrenergic beta agonist used to treat premature labor.
DB00871TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
DB00901BitolterolUsed to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive...
DB00938SalmeterolA beta-2 adrenergic receptor agonist used to treat asthma and COPD.
DB00983FormoterolA beta-2 adrenergic receptor agonist used to treat asthma and COPD.
DB01001SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
DB01102ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
DB01274ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
DB01288FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
DB01291PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
DB01366ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
DB01407ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
DB04861NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
DB05395AmibegronInvestigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity.
DB06152NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
DB06190SolabegronInvestigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.
DB08893MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
DB08941IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
DB08957HexoprenalineHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
DB08985EtilefrineEtilefrine is an adrenergic agonist that appears to interact with beta-2 and some alpha adrenergic receptors. It has been used as a vasoconstrictor agent.
DB09013BefunololUsed in the management of open angle glaucoma. PMID: 12480285.
DB09080OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DB11124RacepinephrineA bronchodilator used to treat intermittent asthma.
DB11541RactopamineNot Annotated
DB12080RitobegronRitobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin...
DB12248TulobuterolTulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
DB12313DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
DB12779HigenamineHigenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).
DB12846ReproterolReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
DB13398OxyfedrineNot Annotated
DB13559RimiterolNot Annotated
DB13624MethoxyphenamineNot Annotated
DB13692TretoquinolNot Annotated
DB13777PrenalterolNot Annotated
DB13781XamoterolXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but...
DB01364EphedrineAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
DB12100AbediterolAbediterol has been used in trials studying the treatment of Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Obstructive Pulmonary Disease (COPD) and Asthma.
DB05039IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
DB13139LevosalbutamolA corticosteroid used to treat COPD and asthma.
DB00368NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
DB01408BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
DB06262DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
DB00449DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
DB01363Ephedra sinica rootAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
DB00397PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
DB09082VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB09273DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
DB06814ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
DB11587EtafedrineA beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.
DB11871PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
DB00852PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
DB12526BatefenterolBatefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
DrugDrug NameTargetType
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB00841DobutamineBeta-1 adrenergic receptortarget
DB00841DobutamineCatechol O-methyltransferaseenzyme
DB00841DobutamineBeta-2 adrenergic receptortarget
DB00841DobutamineAlpha-1 adrenergic receptorstarget
DB00841DobutamineEstrogen receptor alphatarget
DB01064IsoprenalineBeta-1 adrenergic receptortarget
DB01064IsoprenalineBeta-2 adrenergic receptortarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB01064IsoprenalineBeta-3 adrenergic receptortarget
DB01064IsoprenalineMitogen-activated protein kinase 1target
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
DB01064IsoprenalineCytochrome P450 1A1enzyme
DB01064IsoprenalineCAMP phosphodiesterasetarget
DB01064IsoprenalineSuperoxide dismutase [Cu-Zn]target
DB00221IsoetarineBeta-1 adrenergic receptortarget
DB00221IsoetarineBeta-2 adrenergic receptortarget
DB00816OrciprenalineBeta-2 adrenergic receptortarget
DB00867RitodrineBeta-2 adrenergic receptortarget
DB00867Ritodrine6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00871TerbutalineBeta-2 adrenergic receptortarget
DB00871TerbutalineCholinesteraseenzyme
DB00871TerbutalineBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-1 adrenergic receptortarget
DB00901BitolterolBeta-2 adrenergic receptortarget
DB00938SalmeterolBeta-2 adrenergic receptortarget
DB00938SalmeterolCytochrome P450 3A4enzyme
DB00938SalmeterolCytochrome P450 2C8enzyme
DB00938SalmeterolCytochrome P450 3A5enzyme
DB00938SalmeterolCytochrome P450 3A7enzyme
DB00938SalmeterolBeta-1 adrenergic receptortarget
DB00938SalmeterolBeta-3 adrenergic receptortarget
DB00983FormoterolBeta-2 adrenergic receptortarget
DB00983FormoterolCytochrome P450 2C19enzyme
DB00983FormoterolCytochrome P450 2C9enzyme
DB00983FormoterolCytochrome P450 2D6enzyme
DB00983FormoterolCytochrome P450 2A6enzyme
DB00983FormoterolBeta-1 adrenergic receptortarget
DB00983FormoterolBeta-3 adrenergic receptortarget
DB01001SalbutamolBeta-2 adrenergic receptortarget
DB01001SalbutamolBeta-1 adrenergic receptortarget
DB01001SalbutamolCytochrome P450 3A4enzyme
DB01001SalbutamolBeta-3 adrenergic receptortarget
DB01102ArbutamineBeta-1 adrenergic receptortarget
DB01102ArbutamineBeta-2 adrenergic receptortarget
DB01102ArbutamineBeta-3 adrenergic receptortarget
DB01274ArformoterolBeta-2 adrenergic receptortarget
DB01274ArformoterolCytochrome P450 2D6enzyme
DB01274ArformoterolCytochrome P450 2C19enzyme
DB01274ArformoterolCytochrome P450 2A6enzyme
DB01274ArformoterolCytochrome P450 2C9enzyme
DB01288FenoterolBeta-2 adrenergic receptortarget
DB01288FenoterolBeta-1 adrenergic receptortarget
DB01288FenoterolBeta-3 adrenergic receptortarget
DB01291PirbuterolBeta-2 adrenergic receptortarget
DB01291PirbuterolBeta-1 adrenergic receptortarget
DB01366ProcaterolBeta-2 adrenergic receptortarget
DB01407ClenbuterolBeta-2 adrenergic receptortarget
DB01407ClenbuterolBeta-nerve growth factortarget
DB01407ClenbuterolTumor necrosis factortarget
DB01407ClenbuterolBeta-1 adrenergic receptortarget
DB01407ClenbuterolBeta-3 adrenergic receptortarget
DB01407ClenbuterolCytochrome P450 1A1enzyme
DB04861NebivololBeta-1 adrenergic receptortarget
DB04861NebivololCytochrome P450 2D6enzyme
DB04861NebivololBeta-2 adrenergic receptortarget
DB04861NebivololCytochrome P450 3A4enzyme
DB04861NebivololSerum albumincarrier
DB04861NebivololBeta-3 adrenergic receptortarget
DB04861NebivololCytochrome P450 2C19enzyme
DB05395AmibegronBeta-3 adrenergic receptortarget
DB06152NylidrinCatechol O-methyltransferaseenzyme
DB06152NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB06152NylidrinInterferon alpha/beta receptor 2target
DB06152NylidrinCytochrome P450 3A4enzyme
DB06190SolabegronBeta-3 adrenergic receptortarget
DB08893MirabegronCytochrome P450 3A4enzyme
DB08893MirabegronCytochrome P450 2D6enzyme
DB08893MirabegronP-glycoprotein 1transporter
DB08893MirabegronSolute carrier organic anion transporter family member 1A2transporter
DB08893MirabegronSerum albumincarrier
DB08893MirabegronAlpha-1-acid glycoprotein 1carrier
DB08893MirabegronCholinesteraseenzyme
DB08893MirabegronBeta-3 adrenergic receptortarget
DB09013BefunololBeta-1 adrenergic receptortarget
DB09013BefunololBeta-2 adrenergic receptortarget
DB09013BefunololCytochrome P450 2D6enzyme
DB09080OlodaterolBeta-2 adrenergic receptortarget
DB09080OlodaterolCytochrome P450 2C9enzyme
DB09080OlodaterolCytochrome P450 2C8enzyme
DB11124RacepinephrineAlpha-1A adrenergic receptortarget
DB11124RacepinephrineAlpha-1B adrenergic receptortarget
DB11124RacepinephrineAlpha-2A adrenergic receptortarget
DB11124RacepinephrineAlpha-2B adrenergic receptortarget
DB11124RacepinephrineAlpha-2C adrenergic receptortarget
DB11124RacepinephrineBeta-1 adrenergic receptortarget
DB11124RacepinephrineBeta-2 adrenergic receptortarget
DB11124RacepinephrineAlpha-1D adrenergic receptortarget
DB11124RacepinephrineBeta-3 adrenergic receptortarget
DB11541RactopamineEstrogen receptor alphatarget
DB12248TulobuterolBeta-2 adrenergic receptortarget
DB13781XamoterolBeta-1 adrenergic receptortarget
DB01364EphedrineAcetylcholinesterasetarget
DB01364EphedrineAlpha-1A adrenergic receptortarget
DB01364EphedrineSodium-dependent noradrenaline transportertarget
DB01364EphedrineSynaptic vesicular amine transportertarget
DB01364EphedrineCholinesteraseenzyme
DB05039IndacaterolBeta-2 adrenergic receptortarget
DB05039IndacaterolCytochrome P450 3A4enzyme
DB05039IndacaterolUDP-glucuronosyltransferase 1-1enzyme
DB05039IndacaterolP-glycoprotein 1transporter
DB13139LevosalbutamolBeta-2 adrenergic receptortarget
DB13139LevosalbutamolCytochrome P450 3A4enzyme
DB13139LevosalbutamolCytochrome P450 2D6enzyme
DB13139LevosalbutamolSolute carrier organic anion transporter family member 1B1transporter
DB13139LevosalbutamolSolute carrier organic anion transporter family member 1B3transporter
DB00368NorepinephrinePhenylalanine-4-hydroxylasetarget
DB00368NorepinephrineAlpha-1A adrenergic receptortarget
DB00368NorepinephrineAlpha-1B adrenergic receptortarget
DB00368NorepinephrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrineAlpha-2A adrenergic receptortarget
DB00368NorepinephrineAlpha-2B adrenergic receptortarget
DB00368NorepinephrineAlpha-2C adrenergic receptortarget
DB00368NorepinephrineBeta-1 adrenergic receptortarget
DB00368NorepinephrineBeta-2 adrenergic receptortarget
DB00368NorepinephrineBeta-3 adrenergic receptortarget
DB00368NorepinephrineSolute carrier family 22 member 2transporter
DB00368NorepinephrineSolute carrier family 22 member 3transporter
DB00368NorepinephrineSolute carrier family 22 member 5transporter
DB00368NorepinephrineSolute carrier family 22 member 1transporter
DB00368NorepinephrinePOU domain, class 5, transcription factor 1transporter
DB00368NorepinephrineSodium-dependent noradrenaline transportertransporter
DB00368NorepinephrineSynaptic vesicular amine transportertarget
DB00368NorepinephrineChromaffin granule amine transportertarget
DB01408BambuterolBeta-2 adrenergic receptortarget
DB01408BambuterolCholinesteraseenzyme
DB06262DroxidopaPhenylalanine-4-hydroxylasetarget
DB06262DroxidopaAlpha-1A adrenergic receptortarget
DB06262DroxidopaAlpha-1B adrenergic receptortarget
DB06262DroxidopaAlpha-1D adrenergic receptortarget
DB06262DroxidopaAlpha-2A adrenergic receptortarget
DB06262DroxidopaAlpha-2B adrenergic receptortarget
DB06262DroxidopaAlpha-2C adrenergic receptortarget
DB06262DroxidopaBeta-1 adrenergic receptortarget
DB06262DroxidopaBeta-2 adrenergic receptortarget
DB06262DroxidopaBeta-3 adrenergic receptortarget
DB06262DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DB06262DroxidopaMonocarboxylate transporter 10transporter
DB06262DroxidopaSodium-dependent noradrenaline transportertransporter
DB00449DipivefrinAlpha-2A adrenergic receptortarget
DB00449DipivefrinCholinesterasetarget
DB00449DipivefrinBeta-2 adrenergic receptortarget
DB00449DipivefrinAlpha-1A adrenergic receptortarget
DB00449DipivefrinAcetylcholinesterasetarget
DB01363Ephedra sinica rootSodium-dependent dopamine transportertarget
DB01363Ephedra sinica rootSynaptic vesicular amine transportertarget
DB01363Ephedra sinica rootChromaffin granule amine transportertarget
DB01363Ephedra sinica rootSodium-dependent noradrenaline transportertarget
DB01363Ephedra sinica rootAmine oxidase [flavin-containing] Atarget
DB01363Ephedra sinica rootAmine oxidase [flavin-containing] Btarget
DB01363Ephedra sinica rootSodium-dependent serotonin transportertarget
DB01363Ephedra sinica rootAlpha-2A adrenergic receptortarget
DB01363Ephedra sinica rootAlpha-2B adrenergic receptortarget
DB01363Ephedra sinica rootAlpha-2C adrenergic receptortarget
DB01363Ephedra sinica rootBeta-1 adrenergic receptortarget
DB01363Ephedra sinica rootBeta-2 adrenergic receptortarget
DB01363Ephedra sinica rootBeta-3 adrenergic receptortarget
DB00397PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
DB00397PhenylpropanolamineDopamine D1 receptortarget
DB00397PhenylpropanolamineBeta-1 adrenergic receptortarget
DB00397PhenylpropanolamineBeta-2 adrenergic receptortarget
DB00397PhenylpropanolamineAlpha-2 adrenergic receptorstarget
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget
DB04846CeliprololCytochrome P450 2D6enzyme
DB09273DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DB09273DoxofyllineAdenosine receptor A2atarget
DB09273DoxofyllineBeta-2 adrenergic receptortarget
DB09273DoxofyllineCytochrome P450 1A2enzyme
DB06814ProtokylolBeta-2 adrenergic receptortarget
DB11587EtafedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineAlpha-1A adrenergic receptortarget
DB00852PseudoephedrineAlpha-2A adrenergic receptortarget
DB00852PseudoephedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
DB00852PseudoephedrineBeta-1 adrenergic receptortarget
DB00852PseudoephedrineSodium-dependent dopamine transportertarget
DB00852PseudoephedrineSodium-dependent noradrenaline transportertarget
DB00852PseudoephedrineSodium-dependent serotonin transportertarget
DB00852PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
DB00852PseudoephedrineTumor necrosis factortarget
DB00852PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
DB00852Pseudoephedrineactivator protein 1target
DB00852PseudoephedrineInterleukin-2target