Adrenergic beta-Agonists

Name
Adrenergic beta-Agonists
Accession Number
DBCAT000553
Description

Drugs that selectively bind to and activate beta-adrenergic receptors.

Drugs
DrugDrug Description
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
IsoetharineFor the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
RitodrineAn adrenergic beta agonist used to treat premature labor.
TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
BitolterolUsed to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive...
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
AmibegronInvestigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity.
NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
SolabegronInvestigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.
MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
HexoprenalineHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
EtilefrineEtilefrine is an adrenergic agonist that appears to interact with beta-2 and some alpha adrenergic receptors. It has been used as a vasoconstrictor agent.
BefunololUsed in the management of open angle glaucoma. PMID: 12480285.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
RacepinephrineA bronchodilator used to treat intermittent asthma.
RactopamineNot Annotated
RitobegronRitobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin...
TulobuterolTulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
HigenamineHigenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).
ReproterolReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
OxyfedrineNot Annotated
RimiterolNot Annotated
MethoxyphenamineNot Annotated
TretoquinolNot Annotated
PrenalterolNot Annotated
XamoterolXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but...
EphedrineAn alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
AbediterolAbediterol has been used in trials studying the treatment of Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Obstructive Pulmonary Disease (COPD) and Asthma.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
LevosalbutamolA beta-2 adrenergic receptor agonist used to treat COPD and asthma.
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
Ephedra sinica rootAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
EtafedrineA beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.
PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
BatefenterolBatefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Drugs & Drug Targets
DrugTargetType
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptor alphatarget
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineMitogen-activated protein kinase 1target
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineCAMP phosphodiesterasetarget
IsoprenalineSuperoxide dismutase [Cu-Zn]target
IsoetharineBeta-1 adrenergic receptortarget
IsoetharineBeta-2 adrenergic receptortarget
OrciprenalineBeta-2 adrenergic receptortarget
RitodrineBeta-2 adrenergic receptortarget
Ritodrine6-phosphogluconate dehydrogenase, decarboxylatingenzyme
TerbutalineBeta-2 adrenergic receptortarget
TerbutalineCholinesteraseenzyme
TerbutalineBeta-3 adrenergic receptortarget
TerbutalineBeta-1 adrenergic receptortarget
BitolterolBeta-2 adrenergic receptortarget
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
SalbutamolBeta-2 adrenergic receptortarget
SalbutamolBeta-1 adrenergic receptortarget
SalbutamolCytochrome P450 3A4enzyme
SalbutamolBeta-3 adrenergic receptortarget
ArbutamineBeta-1 adrenergic receptortarget
ArbutamineBeta-2 adrenergic receptortarget
ArbutamineBeta-3 adrenergic receptortarget
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
PirbuterolBeta-2 adrenergic receptortarget
PirbuterolBeta-1 adrenergic receptortarget
ProcaterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-nerve growth factortarget
ClenbuterolTumor necrosis factortarget
ClenbuterolBeta-1 adrenergic receptortarget
ClenbuterolBeta-3 adrenergic receptortarget
ClenbuterolCytochrome P450 1A1enzyme
NebivololBeta-1 adrenergic receptortarget
NebivololCytochrome P450 2D6enzyme
NebivololBeta-2 adrenergic receptortarget
NebivololCytochrome P450 3A4enzyme
NebivololSerum albumincarrier
NebivololBeta-3 adrenergic receptortarget
NebivololCytochrome P450 2C19enzyme
AmibegronBeta-3 adrenergic receptortarget
NylidrinCatechol O-methyltransferaseenzyme
NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NylidrinInterferon alpha/beta receptor 2target
NylidrinCytochrome P450 3A4enzyme
SolabegronBeta-3 adrenergic receptortarget
MirabegronCytochrome P450 3A4enzyme
MirabegronCytochrome P450 2D6enzyme
MirabegronP-glycoprotein 1transporter
MirabegronSolute carrier organic anion transporter family member 1A2transporter
MirabegronSerum albumincarrier
MirabegronAlpha-1-acid glycoprotein 1carrier
MirabegronCholinesteraseenzyme
MirabegronBeta-3 adrenergic receptortarget
BefunololBeta-1 adrenergic receptortarget
BefunololBeta-2 adrenergic receptortarget
BefunololCytochrome P450 2D6enzyme
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
RactopamineEstrogen receptor alphatarget
TulobuterolBeta-2 adrenergic receptortarget
XamoterolBeta-1 adrenergic receptortarget
EphedrineAlpha-1A adrenergic receptortarget
EphedrineSodium-dependent noradrenaline transportertarget
EphedrineCholinesteraseenzyme
EphedrineSerum albumincarrier
EphedrineBeta-1 adrenergic receptortarget
EphedrineBeta-2 adrenergic receptortarget
EphedrineSynaptic vesicular amine transportertransporter
EphedrineAcetylcholinesteraseenzyme
IndacaterolBeta-2 adrenergic receptortarget
IndacaterolCytochrome P450 3A4enzyme
IndacaterolUDP-glucuronosyltransferase 1-1enzyme
IndacaterolP-glycoprotein 1transporter
LevosalbutamolBeta-2 adrenergic receptortarget
LevosalbutamolCytochrome P450 3A4enzyme
LevosalbutamolCytochrome P450 2D6enzyme
LevosalbutamolSolute carrier organic anion transporter family member 1B1transporter
LevosalbutamolSolute carrier organic anion transporter family member 1B3transporter
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
BambuterolBeta-2 adrenergic receptortarget
BambuterolCholinesteraseenzyme
DroxidopaPhenylalanine-4-hydroxylasetarget
DroxidopaAlpha-1A adrenergic receptortarget
DroxidopaAlpha-1B adrenergic receptortarget
DroxidopaAlpha-1D adrenergic receptortarget
DroxidopaAlpha-2A adrenergic receptortarget
DroxidopaAlpha-2B adrenergic receptortarget
DroxidopaAlpha-2C adrenergic receptortarget
DroxidopaBeta-1 adrenergic receptortarget
DroxidopaBeta-2 adrenergic receptortarget
DroxidopaBeta-3 adrenergic receptortarget
DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DroxidopaMonocarboxylate transporter 10transporter
DroxidopaSodium-dependent noradrenaline transportertransporter
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
Ephedra sinica rootSodium-dependent dopamine transportertarget
Ephedra sinica rootSynaptic vesicular amine transportertarget
Ephedra sinica rootChromaffin granule amine transportertarget
Ephedra sinica rootSodium-dependent noradrenaline transportertarget
Ephedra sinica rootAmine oxidase [flavin-containing] Atarget
Ephedra sinica rootAmine oxidase [flavin-containing] Btarget
Ephedra sinica rootSodium-dependent serotonin transportertarget
Ephedra sinica rootAlpha-2A adrenergic receptortarget
Ephedra sinica rootAlpha-2B adrenergic receptortarget
Ephedra sinica rootAlpha-2C adrenergic receptortarget
Ephedra sinica rootBeta-1 adrenergic receptortarget
Ephedra sinica rootBeta-2 adrenergic receptortarget
Ephedra sinica rootBeta-3 adrenergic receptortarget
PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
PhenylpropanolamineDopamine D1 receptortarget
PhenylpropanolamineBeta-1 adrenergic receptortarget
PhenylpropanolamineBeta-2 adrenergic receptortarget
PhenylpropanolamineAlpha-2 adrenergic receptorstarget
VilanterolCytochrome P450 3A4enzyme
VilanterolBeta-2 adrenergic receptortarget
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
ProtokylolBeta-2 adrenergic receptortarget
EtafedrineBeta-2 adrenergic receptortarget
PseudoephedrineAlpha-1A adrenergic receptortarget
PseudoephedrineAlpha-2A adrenergic receptortarget
PseudoephedrineBeta-2 adrenergic receptortarget
PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
PseudoephedrineBeta-1 adrenergic receptortarget
PseudoephedrineSodium-dependent dopamine transportertarget
PseudoephedrineSodium-dependent noradrenaline transportertarget
PseudoephedrineSodium-dependent serotonin transportertarget
PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
PseudoephedrineTumor necrosis factortarget
PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
Pseudoephedrineactivator protein 1target
PseudoephedrineInterleukin-2target
PseudoephedrineSerum albumincarrier
PseudoephedrineSodium-dependent noradrenaline transportertransporter
PseudoephedrineSodium-dependent dopamine transportertransporter
PseudoephedrineSodium-dependent serotonin transportertransporter