Electrolyte Solutions

DrugDrug NameDrug Indication
DB00653Magnesium sulfateUsed for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
DB06767Ammonium chloride1. Expectorant in cough syrups. 2. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium (Na+) to combine with fixed anions in maintaining acid-base balance, especially as a homeostatic compensatory mechanism in metabolic acidosis. The therapeutic effects of Ammonium Chloride depend upon the ability of the kidney to utilize ammonia in the excretion of an excess of fixed anions and the conversion of ammonia to urea by the liver, thereby liberating hydrogen (H+) and chloride (Cl–) ions into the extracellular fluid. Ammonium Chloride Injection, USP, after dilution in isotonic sodium chloride injection, may be indicated in the treatment of patients with: (1) hypochloremic states and (2) metabolic alkalosis.
DB09153Sodium chlorideThis intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.
DB09395Sodium acetateInjection, USP 40 mEq is indicated as a source of sodium, for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Sodium acetate and other bicarbonate precursors are alkalinising agents, and can be used to correct metabolic acidosis, or for alkalinisation of the urine.
DB09407Magnesium chlorideMagnesium chloride is used in several medical and topical (skin related) applications. Magnesium chloride usp, anhydrous uses as electrolyte replenisher, pharmaceutic necessity for hemodialysis and peritoneal dialysis fluids.
DB09483Potassium lactateNot Available
DB09561Sodium glycerophosphateSodium glycerophosphate is indicated for use as a source of phosphate in total parenteral nutrition [FDA Label]. It is used in combination with amino acids, dextrose, lipid emulsions, and other electrolytes.
DB13862Magnesium phosphateNot Available
DB00761Potassium chlorideFor use as an electrolyte replenisher and in the treatment of hypokalemia.
DB01164Calcium ChlorideFor the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, for the treatment of magnesium intoxication due to overdosage of magnesium sulfate, and used to combat the deleterious effects of hyperkalemia as measured by electrocardiographic (ECG), pending correction of the increased potassium level in the extracellular fluid.
DB01390Sodium bicarbonateSodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.
DB13366Hydrochloric acidNot Available
DB14498Potassium acetatePotassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.
DB14533Zinc chlorideZinc can be used for the treatment and prevention of zinc deficiency/its consequences, including stunted growth and acute diarrhea in children, and slowed wound healing. It is also utilized for boosting the immune system, treating the common cold and recurrent ear infections, as well as preventing lower respiratory tract infections [L2172].
DrugDrug NameTargetType
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB09395Sodium acetateAcetyl-coenzyme A synthetase, cytoplasmicenzyme
DB00761Potassium chlorideSolute carrier family 12 member 2target
DB00761Potassium chlorideSolute carrier family 12 member 1target
DB00761Potassium chlorideSolute carrier family 12 member 5target
DB00761Potassium chlorideSolute carrier family 12 member 6target
DB00761Potassium chlorideSolute carrier family 12 member 7target
DB00761Potassium chlorideSolute carrier family 12 member 4target
DB00761Potassium chlorideSolute carrier family 12 member 2transporter
DB00761Potassium chlorideSolute carrier family 12 member 1transporter
DB00761Potassium chlorideSolute carrier family 12 member 5transporter
DB00761Potassium chlorideSolute carrier family 12 member 6transporter
DB00761Potassium chlorideSolute carrier family 12 member 7transporter
DB00761Potassium chlorideSolute carrier family 12 member 4transporter
DB01164Calcium ChlorideProtein S100-A13target
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB14498Potassium acetateSodium/potassium-transporting ATPase subunit alpha-1target
DB14533Zinc chlorideB1 bradykinin receptortarget
DB14533Zinc chlorideMethylated-DNA--protein-cysteine methyltransferasetarget
DB14533Zinc chlorideFructose-bisphosphate aldolase Atarget
DB14533Zinc chlorideElongation factor 1-alpha 1target
DB14533Zinc chlorideAlpha-enolasetarget
DB14533Zinc chlorideGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
DB14533Zinc chlorideNucleoside diphosphate kinase Atarget
DB14533Zinc chlorideProtein disulfide-isomerasetarget
DB14533Zinc chlorideProtein disulfide-isomerase A3target
DB14533Zinc chloridePeroxiredoxin-1target
DB14533Zinc chloridePhosphoserine phosphatasetarget
DB14533Zinc chlorideTriosephosphate isomerasetarget
DB14533Zinc chlorideElongation factor Tu, mitochondrialtarget
DB14533Zinc chlorideEstrogen receptor alphatarget
DB14533Zinc chlorideInterleukin-3target
DB14533Zinc chlorideMetallothionein-2target
DB14533Zinc chlorideCopper chaperone for superoxide dismutasetarget
DB14533Zinc chlorideHistone deacetylase 1target
DB14533Zinc chlorideHistone deacetylase 4target
DB14533Zinc chlorideDNA-3-methyladenine glycosylasetarget
DB14533Zinc chlorideSemenogelin-1target
DB14533Zinc chlorideSuperoxide dismutase [Cu-Zn]target
DB14533Zinc chlorideHistone deacetylase 8target
DB14533Zinc chlorideApoptosis regulatory protein Sivatarget
DB14533Zinc chlorideGlycine receptor subunit alpha-1target
DB14533Zinc chlorideE3 ubiquitin-protein ligase Mdm2target
DB14533Zinc chlorideInsulintarget
DB14533Zinc chlorideUtrophintarget
DB14533Zinc chlorideAspartoacylasetarget
DB14533Zinc chlorideProtein S100-A8target
DB14533Zinc chlorideProtein S100-A9target
DB14533Zinc chlorideMatrix metalloproteinase-9target
DB14533Zinc chlorideTumor protein p73target
DB14533Zinc chlorideProtein S100-A2target
DB14533Zinc chlorideCellular tumor antigen p53target
DB14533Zinc chlorideMetallothionein-3target
DB14533Zinc chlorideProgrammed cell death protein 6target
DB14533Zinc chlorideDAN domain family member 5target
DB14533Zinc chlorideMetallothionein-1Atarget
DB14533Zinc chlorideAlpha-1B-glycoproteintarget
DB14533Zinc chlorideAlpha-2-macroglobulintarget
DB14533Zinc chlorideAngiotensinogentarget
DB14533Zinc chlorideAlpha-2-HS-glycoproteintarget
DB14533Zinc chlorideSerum amyloid P-componenttarget
DB14533Zinc chlorideApolipoprotein A-Itarget
DB14533Zinc chlorideApolipoprotein A-IItarget
DB14533Zinc chlorideApolipoprotein A-IVtarget
DB14533Zinc chlorideApolipoprotein B receptortarget
DB14533Zinc chlorideApolipoprotein Etarget
DB14533Zinc chlorideApolipoprotein L1target
DB14533Zinc chlorideComplement C1q subcomponent subunit Btarget
DB14533Zinc chlorideComplement C1q subcomponent subunit Ctarget
DB14533Zinc chlorideComplement C1r subcomponenttarget
DB14533Zinc chlorideComplement C1s subcomponenttarget
DB14533Zinc chlorideComplement C3target
DB14533Zinc chlorideComplement C4-Btarget
DB14533Zinc chlorideC4b-binding protein alpha chaintarget
DB14533Zinc chlorideC4b-binding protein beta chaintarget
DB14533Zinc chlorideComplement C5target
DB14533Zinc chlorideLys-63-specific deubiquitinase BRCC36target
DB14533Zinc chlorideComplement component C8 alpha chaintarget
DB14533Zinc chlorideComplement component C8 beta chaintarget
DB14533Zinc chlorideComplement component C8 gamma chaintarget
DB14533Zinc chlorideComplement factor Btarget
DB14533Zinc chlorideComplement factor Htarget
DB14533Zinc chlorideComplement factor Itarget
DB14533Zinc chlorideClusterintarget
DB14533Zinc chlorideCeruloplasmintarget
DB14533Zinc chlorideCarboxypeptidase N catalytic chaintarget
DB14533Zinc chlorideCarboxypeptidase N subunit 2target
DB14533Zinc chlorideDermcidintarget
DB14533Zinc chlorideDesmoplakintarget
DB14533Zinc chlorideCoagulation factor XIItarget
DB14533Zinc chlorideCoagulation factor XIII B chaintarget
DB14533Zinc chlorideProthrombintarget
DB14533Zinc chlorideFicolin-3target
DB14533Zinc chlorideFibrinogen alpha chaintarget
DB14533Zinc chlorideFibronectintarget
DB14533Zinc chlorideGelsolintarget
DB14533Zinc chlorideHemoglobin subunit alphatarget
DB14533Zinc chlorideHemoglobin subunit betatarget
DB14533Zinc chlorideHaptoglobin-related proteintarget
DB14533Zinc chlorideHornerintarget
DB14533Zinc chlorideInsulin-like growth factor-binding protein complex acid labile subunittarget
DB14533Zinc chlorideIg alpha-1 chain C regiontarget
DB14533Zinc chlorideIg mu chain C regiontarget
DB14533Zinc chlorideImmunoglobulin kappa variable 1-17target
DB14533Zinc chlorideIg kappa chain V-III region GOLtarget
DB14533Zinc chlorideImmunoglobulin lambda variable 3-21target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H1target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H2target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H3target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H4target
DB14533Zinc chlorideImmunoglobulin J chaintarget
DB14533Zinc chlorideJunction plakoglobintarget
DB14533Zinc chloridePlasma kallikreintarget
DB14533Zinc chlorideKininogen-1target
DB14533Zinc chlorideKeratin, type II cytoskeletal 1target
DB14533Zinc chlorideKeratin, type I cytoskeletal 10target
DB14533Zinc chlorideKeratin, type I cytoskeletal 14target
DB14533Zinc chlorideKeratin, type I cytoskeletal 16target
DB14533Zinc chlorideKeratin, type II cytoskeletal 2 epidermaltarget
DB14533Zinc chlorideKeratin, type II cytoskeletal 5target
DB14533Zinc chlorideKeratin, type II cytoskeletal 6Atarget
DB14533Zinc chlorideKeratin, type I cytoskeletal 9target
DB14533Zinc chlorideAlpha-1-acid glycoprotein 2target
DB14533Zinc chlorideN-acetylmuramoyl-L-alanine amidasetarget
DB14533Zinc chlorideSerum paraoxonase/arylesterase 1target
DB14533Zinc chloridePregnancy zone proteintarget
DB14533Zinc chlorideProtein S100-A7target
DB14533Zinc chlorideSelenoprotein Ptarget
DB14533Zinc chlorideAlpha-1-antitrypsintarget
DB14533Zinc chlorideAlpha-1-antichymotrypsintarget
DB14533Zinc chlorideKallistatintarget
DB14533Zinc chlorideCorticosteroid-binding globulintarget
DB14533Zinc chlorideHeparin cofactor 2target
DB14533Zinc chlorideSex hormone-binding globulintarget
DB14533Zinc chlorideSerotransferrintarget
DB14533Zinc chlorideTransthyretintarget
DB14533Zinc chlorideVitronectintarget
DB14533Zinc chlorideAmyloid-like protein 1target
DB14533Zinc chlorideAmyloid-like protein 2target
DB14533Zinc chlorideAmyloid beta A4 proteintarget
DB14533Zinc chloridePoly [ADP-ribose] polymerase 1target
DB14533Zinc chlorideCarbonic anhydrase 1enzyme
DB14533Zinc chlorideCarboxypeptidase Eenzyme
DB14533Zinc chlorideAlcohol dehydrogenase 1Cenzyme
DB14533Zinc chlorideInsulin-degrading enzymeenzyme
DB14533Zinc chlorideSuperoxide dismutase [Cu-Zn]enzyme