Cytochrome P-450 CYP3A4 Inducers (weak)

DrugDrug NameDrug Indication
DB00503RitonavirIndicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
DB00603Medroxyprogesterone acetateUsed as a contraceptive and to treat secondary amenorrhea, abnormal uterine bleeding, pain associated with endometriosis, endometrial and renal cell carcinomas, paraphilia in males, GnRH-dependent forms of precocious puberty, as well as to prevent endometrial changes associated with estrogens.
DB00635PrednisoneFor the treatment of drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis, Crohn's disease, acquired hemolytic anemia, congenital hypoplastic anemia, erythroblastopenia, adult secondary thrombocytopenia, adult idiopathic thrombocytopenia purpura, acute or subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute or chronic lymphocytic leukemia, Hodgkin's or non-Hodgkin's lynphomas, Waldenstrom's macroglobulinemia, primary brain tumors (adjunct), nephrotic syndrome, tuberculous meningitis, multiple sclerosis, myasthenia gravis. cerebral edema, chorioretinitis, diffuse posterior choroiditis, aleergic conjunctivitis, Herpes zoster ophthalmicus, anterior segment inflammation, iridocyclitis, iritis, keratitis, optoc neuritis, sympathetic ophthalmia, corneal marginal allergic ulcers, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy and aspiration pneumonitis.
DB00741HydrocortisoneFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB00990ExemestaneFor the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
DB01132PioglitazonePioglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [FDA Label].
DB01229PaclitaxelUsed in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast. Abraxane® is specfically indicated for the treatment of metastatic breast cancer and locally advanced or metastatic non-small cell lung cancer.
DB01601LopinavirIndicated in combination with other antiretroviral agents for the treatment of HIV-infection.
DB01011MetyraponeUsed as a diagnostic drug for testing hypothalamic-pituitary ACTH function. Occasionally used in Cushing's syndrome.
DB00857TerbinafineFor the treatment of dermatophyte infections of the toenail or fingernail caused by susceptible fungi. Also for the treatment of tinea capitis (scalp ringworm) and tinea corporis (body ringworm) or tinea cruris (jock itch).
DB00783EstradiolFor the treatment of urogenital symptoms associated with post-menopausal atrophy of the vagina (such as dryness, burning, pruritus and dyspareunia) and/or the lower urinary tract (urinary urgency and dysuria).
DB06413ArmodafinilInvestigated for use/treatment in sleep disorders, obstructive sleep apnea, schizophrenia and schizoaffective disorders, depression, and bipolar disorders.
DB00136CalcitriolUsed to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or corticosteroid-induced osteoporosis.
DB00349ClobazamFor treatment and management of epilepsy and seizures associated with Lennox-Gastaut syndrome, a difficult-to-treat form of childhood epilepsy.
DB00949FelbamateFor use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.
DB00776OxcarbazepineFor use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy and as adjunctive therapy in the treatment of partial seizures in children ages 4-16 with epilepsy.
DB06700DesvenlafaxineDesvenlafaxine is indicated for the treatment of major depressive disorder in adults.
DB06697ArtemetherArtemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 kg.
DB06708LumefantrineLumefantrine and artemether combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 kg.
DB00273TopiramateUsed for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. Qsymia® is indicated for the treatment and management of obesity.
DB00400GriseofulvinFor the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
DB01609DeferasiroxFor the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
DB00485DicloxacillinUsed to treat infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug.
DB08881VemurafenibTreatment of unresectable or metastatic melanoma in patients with the BRAF-V600 mutation.
DB08883PerampanelUsed in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
DB06201RufinamideAdjunct therapy for treatment of seizures associated with Lennox-Gastaut syndrome.
DB08911TrametinibTrametinib is indicated for the treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test.
DB06636IsavuconazoniumIndicated in the treatment of invasive aspergillosis and invasive mucormycosis.
DB00957NorgestimateFor the prevention of pregnancy
DB01395DrospirenoneFor the prevention of pregnancy in women who elect an oral contraceptive.
DB04911OritavancinInvestigated for use/treatment in bacterial infection and skin infections/disorders.
DB06717FosaprepitantFor the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
DB11943DelafloxacinDelafloxacin is indicated for the treatment of acute bacterial skin and skin structure infections caused by the Gram-positive organisms Staphylococcus aureus (including methicillin-resistant and methicillin-susceptible isolates), Staphylococcus haemolyticus, Staphylococcus lugdunensis, Streptococcus agalactiae, Streptococcus anginosus Group (including Streptococcus anginosus, Streptococcus intermedius, and Streptococcus constellatus), Streptococcus pyogenes, and Enterococcus faecalis as well as the Gram-negative organisms Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, and Pseudomonas aeruginosa [FDA Label].
DrugDrug NameTargetType
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirMultidrug resistance protein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00603Medroxyprogesterone acetateProgesterone receptortarget
DB00603Medroxyprogesterone acetateEstrogen receptor alphatarget
DB00603Medroxyprogesterone acetateCytochrome P450 3A4enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C8enzyme
DB00603Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C9enzyme
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneMultidrug resistance protein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1target
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneMultidrug resistance protein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneATP-binding cassette sub-family G member 2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00741Hydrocortisone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB00990ExemestaneCytochrome P450 19A1target
DB00990ExemestaneCytochrome P450 3A4enzyme
DB00990ExemestaneCytochrome P450 19A1enzyme
DB01132PioglitazonePeroxisome proliferator-activated receptor gammatarget
DB01132PioglitazoneCytochrome P450 2C8enzyme
DB01132PioglitazoneCytochrome P450 3A4enzyme
DB01132PioglitazoneSolute carrier organic anion transporter family member 1B3transporter
DB01132PioglitazoneSolute carrier organic anion transporter family member 1B1transporter
DB01132PioglitazoneProstaglandin G/H synthase 1enzyme
DB01132PioglitazoneCytochrome P450 2C19enzyme
DB01132PioglitazoneCytochrome P450 2C9enzyme
DB01132PioglitazoneCytochrome P450 2D6enzyme
DB01132PioglitazonePeroxisome proliferator-activated receptor deltatarget
DB01132PioglitazonePeroxisome proliferator-activated receptor alphatarget
DB01132PioglitazoneAmine oxidase [flavin-containing] Btarget
DB01229PaclitaxelApoptosis regulator Bcl-2target
DB01229PaclitaxelTubulin beta-1 chaintarget
DB01229PaclitaxelCytochrome P450 2C8enzyme
DB01229PaclitaxelCytochrome P450 3A4enzyme
DB01229PaclitaxelCytochrome P450 3A5enzyme
DB01229PaclitaxelCytochrome P450 3A7enzyme
DB01229PaclitaxelCytochrome P450 2C9enzyme
DB01229PaclitaxelBile salt export pumptransporter
DB01229PaclitaxelMultidrug resistance protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 7transporter
DB01229PaclitaxelCytochrome P450 19A1enzyme
DB01229PaclitaxelCytochrome P450 1B1enzyme
DB01229PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
DB01229PaclitaxelNuclear receptor subfamily 1 group I member 2target
DB01229PaclitaxelMicrotubule-associated protein 4target
DB01229PaclitaxelMicrotubule-associated protein 2target
DB01229PaclitaxelMicrotubule-associated protein tautarget
DB01229PaclitaxelATP-binding cassette sub-family G member 2transporter
DB01229PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DB01601LopinavirHuman immunodeficiency virus type 1 proteasetarget
DB01601LopinavirCytochrome P450 3A4enzyme
DB01601LopinavirCytochrome P450 2D6enzyme
DB01601LopinavirCytochrome P450 2C19enzyme
DB01601LopinavirMultidrug resistance protein 1transporter
DB01601LopinavirCytochrome P450 1A2enzyme
DB01601LopinavirCytochrome P450 2B6enzyme
DB01601LopinavirCytochrome P450 2C9enzyme
DB01601LopinavirCytochrome P450 2C8enzyme
DB01011MetyraponeCamphor 5-monooxygenasetarget
DB01011MetyraponeCytochrome P450 11B2, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2A6enzyme
DB01011MetyraponeCytochrome P450 3A4enzyme
DB01011MetyraponeCanalicular multispecific organic anion transporter 2transporter
DB01011MetyraponeCytochrome P450 11B1, mitochondrialtarget
DB01011MetyraponeCytochrome P450 11B1, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2E1enzyme
DB00857TerbinafineSqualene monooxygenasetarget
DB00857TerbinafineCytochrome P450 2D6enzyme
DB00857TerbinafineCytochrome P450 2C9enzyme
DB00857TerbinafineCytochrome P450 1A2enzyme
DB00857TerbinafineCytochrome P450 3A4enzyme
DB00857TerbinafineCytochrome P450 2C8enzyme
DB00857TerbinafineCytochrome P450 2C19enzyme
DB00857TerbinafineProstaglandin G/H synthase 1enzyme
DB00857TerbinafineCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00857TerbinafineCytochrome P450 19A1enzyme
DB00783EstradiolEstrogen receptor alphatarget
DB00783EstradiolNuclear receptor subfamily 1 group I member 2target
DB00783EstradiolSex hormone-binding globulincarrier
DB00783EstradiolEstrogen receptor betatarget
DB00783EstradiolCytochrome P450 1A2enzyme
DB00783EstradiolUDP-glucuronosyltransferase 1-1enzyme
DB00783EstradiolSerum albumincarrier
DB00783EstradiolFatty acid-binding protein, intestinalcarrier
DB00783EstradiolCytochrome P450 3A4enzyme
DB00783EstradiolCytochrome P450 3A5enzyme
DB00783EstradiolCytochrome P450 3A7enzyme
DB00783EstradiolSolute carrier family 22 member 2transporter
DB00783EstradiolSolute carrier family 22 member 1transporter
DB00783EstradiolSolute carrier family 22 member 3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 2B1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1A2transporter
DB00783EstradiolMultidrug resistance-associated protein 7transporter
DB00783EstradiolSolute carrier family 22 member 11transporter
DB00783EstradiolATP-binding cassette sub-family G member 2transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B1transporter
DB00783EstradiolMultidrug resistance protein 1transporter
DB00783EstradiolCytochrome P450 1A1enzyme
DB00783EstradiolCytochrome P450 1B1enzyme
DB00783EstradiolCytochrome P450 2C19enzyme
DB00783EstradiolCytochrome P450 2C8enzyme
DB00783EstradiolCytochrome P450 2C9enzyme
DB00783EstradiolSolute carrier family 22 member 8transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1C1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 4A1transporter
DB00783EstradiolNeuronal acetylcholine receptor subunit alpha-4target
DB00783EstradiolNuclear receptor coactivator 2target
DB00783EstradiolG-protein coupled estrogen receptor 1target
DB00783EstradiolATP synthase subunit atarget
DB00783EstradiolBeclin-1target
DB00783EstradiolEstradiol 17-beta-dehydrogenase 2target
DB00783EstradiolEstrogen-related receptor gammatarget
DB06413ArmodafinilCytochrome P450 2C19enzyme
DB06413ArmodafinilCytochrome P450 3A4enzyme
DB06413ArmodafinilCytochrome P450 1A2enzyme
DB06413ArmodafinilCytochrome P450 2B6enzyme
DB06413ArmodafinilCytochrome P450 3A5enzyme
DB06413ArmodafinilCytochrome P450 2C9enzyme
DB06413ArmodafinilSodium-dependent dopamine transportertarget
DB00136CalcitriolVitamin D3 receptortarget
DB00136Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00136CalcitriolCytochrome P450 3A4enzyme
DB00136CalcitriolHomeobox protein Hox-A10target
DB00136CalcitriolVitamin D-binding proteintarget
DB00349ClobazamCytochrome P450 2C19enzyme
DB00349ClobazamCytochrome P450 3A4enzyme
DB00349ClobazamCytochrome P450 2B6enzyme
DB00349ClobazamCytochrome P450 2C18enzyme
DB00349ClobazamSodium- and chloride-dependent GABA transporter 1transporter
DB00349ClobazamSodium- and chloride-dependent GABA transporter 3transporter
DB00349ClobazamMultidrug resistance protein 1transporter
DB00349ClobazamGABA-A receptor (anion channel)target
DB00349ClobazamCytochrome P450 2D6enzyme
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00776OxcarbazepineSodium channel protein type 5 subunit alphatarget
DB00776OxcarbazepineCytochrome P450 2C19enzyme
DB00776OxcarbazepineCytochrome P450 3A4enzyme
DB00776OxcarbazepineCytochrome P450 3A5enzyme
DB00776OxcarbazepineSerum albumincarrier
DB06700DesvenlafaxineCytochrome P450 3A4enzyme
DB06700DesvenlafaxineSodium-dependent serotonin transportertarget
DB06700DesvenlafaxineSodium-dependent noradrenaline transportertarget
DB06697ArtemetherCytochrome P450 3A4enzyme
DB06697ArtemetherCytochrome P450 3A5enzyme
DB06697ArtemetherCytochrome P450 2B6enzyme
DB06697ArtemetherCytochrome P450 2C9enzyme
DB06697ArtemetherCytochrome P450 2C19enzyme
DB06697ArtemetherCytochrome P450 2D6enzyme
DB06708LumefantrineCytochrome P450 2D6enzyme
DB06708LumefantrineCytochrome P450 3A4enzyme
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateSodium channel protein type 1 subunit alphatarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateGlutamate receptor ionotropic, kainate 1target
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateGABA-A receptor (anion channel)target
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00400GriseofulvinTubulin beta chaintarget
DB00400GriseofulvinTubulin alpha chaintarget
DB00400GriseofulvinKeratin, type I cytoskeletal 12target
DB00400GriseofulvinCytochrome P450 1A2enzyme
DB00400GriseofulvinCytochrome P450 3A4enzyme
DB01609DeferasiroxIrontarget
DB01609DeferasiroxCytochrome P450 3A4enzyme
DB00485DicloxacillinSolute carrier family 15 member 1transporter
DB00485DicloxacillinSolute carrier family 15 member 2transporter
DB00485DicloxacillinPenicillin-binding protein 3target
DB00485DicloxacillinPenicillin-binding protein 1btarget
DB00485DicloxacillinPenicillin-binding protein 2atarget
DB00485DicloxacillinPenicillin-binding protein 3target
DB00485DicloxacillinPenicillin-binding protein 1Atarget
DB00485DicloxacillinPenicillin-binding protein 2Btarget
DB00485DicloxacillinCytochrome P450 3A4enzyme
DB08881VemurafenibSerum albumincarrier
DB08881VemurafenibAlpha-1-acid glycoprotein 1carrier
DB08881VemurafenibCytochrome P450 1A2enzyme
DB08881VemurafenibCytochrome P450 2D6enzyme
DB08881VemurafenibCytochrome P450 3A4enzyme
DB08881VemurafenibSerine/threonine-protein kinase B-raftarget
DB08881VemurafenibMultidrug resistance-associated protein 1transporter
DB08881VemurafenibATP-binding cassette sub-family G member 2transporter
DB08883PerampanelGlutamate receptor 1target
DB08883PerampanelCytochrome P450 3A4enzyme
DB08883PerampanelCytochrome P450 3A5enzyme
DB06201RufinamideMetabotropic glutamate receptor 5target
DB06201RufinamideLiver carboxylesterase 1enzyme
DB06201RufinamideSodium channel protein type 9 subunit alphatarget
DB06201RufinamideSerum albumincarrier
DB06201RufinamideCytochrome P450 2E1enzyme
DB06201RufinamideCytochrome P450 3A4enzyme
DB08911TrametinibCytochrome P450 2C8enzyme
DB08911TrametinibCytochrome P450 3A4enzyme
DB08911TrametinibDual specificity mitogen-activated protein kinase kinase 1target
DB08911TrametinibDual specificity mitogen-activated protein kinase kinase 2target
DB06636IsavuconazoniumCytochrome P450 3A4enzyme
DB06636IsavuconazoniumMultidrug resistance protein 1transporter
DB00957NorgestimateProgesterone receptortarget
DB00957NorgestimateEstrogen receptor alphatarget
DB00957NorgestimateCanalicular multispecific organic anion transporter 1transporter
DB00957NorgestimateCytochrome P450 3A4enzyme
DB00957NorgestimateAndrogen receptortarget
DB01395DrospirenoneProgesterone receptortarget
DB01395DrospirenoneMineralocorticoid receptortarget
DB01395DrospirenoneAndrogen receptortarget
DB01395DrospirenoneProstaglandin G/H synthase 2enzyme
DB01395DrospirenoneCholinesteraseenzyme
DB01395DrospirenoneCytochrome P450 3A4enzyme
DB04911OritavancinCytochrome P450 3A4enzyme
DB06717FosaprepitantCytochrome P450 3A4enzyme
DB11943DelafloxacinUDP-glucuronosyltransferase 1-1enzyme
DB11943DelafloxacinUDP-glucuronosyltransferase 1-3enzyme
DB11943DelafloxacinUDP-glucuronosyltransferase 2B15enzyme
DB11943DelafloxacinDNA topoisomerase 4 subunit Atarget
DB11943DelafloxacinDNA gyrase subunit Atarget
DB11943DelafloxacinCytochrome P450 2E1enzyme
DB11943DelafloxacinCytochrome P450 2C9enzyme
DB11943DelafloxacinCytochrome P450 3A4enzyme
DB11943DelafloxacinATP-binding cassette sub-family B member 5transporter
DB11943DelafloxacinATP-binding cassette sub-family G member 2transporter
DB11943DelafloxacinSerum albumincarrier