Indenolol

Identification

Name
Indenolol
Accession Number
DB08952
Type
Small Molecule
Groups
Withdrawn
Description

Indenolol is a drug of the beta-adrenergic blocker class.

Structure
Thumb
Synonyms
Not Available
Categories
UNII
3MZM7RWW00
CAS number
60607-68-3
Weight
Average: 247.3327
Monoisotopic: 247.157228921
Chemical Formula
C15H21NO2
InChI Key
MPGBPFMOOXKQRX-UHFFFAOYSA-N
InChI
InChI=1S/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3
IUPAC Name
1-(1H-inden-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=CC2

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
1,10-Phenanthroline1,10-Phenanthroline may increase the bradycardic activities of Indenolol.Experimental
4-Methoxyamphetamine4-Methoxyamphetamine may increase the atrioventricular blocking (AV block) activities of Indenolol.Experimental, Illicit
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the hypotensive activities of Indenolol.Experimental
AcebutololAcebutolol may increase the hypotensive activities of Indenolol.Approved
AceclofenacAceclofenac may decrease the antihypertensive activities of Indenolol.Approved, Investigational
AcemetacinAcemetacin may decrease the antihypertensive activities of Indenolol.Approved, Experimental, Investigational
AcepromazineAcepromazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
AceprometazineAceprometazine may increase the hypotensive activities of Indenolol.Approved
AcetohexamideIndenolol may increase the hypoglycemic activities of Acetohexamide.Investigational, Withdrawn
AcetylcholineThe risk or severity of adverse effects can be increased when Indenolol is combined with Acetylcholine.Approved
AcetyldigitoxinIndenolol may increase the bradycardic activities of Acetyldigitoxin.Approved
AcetyldigoxinIndenolol may increase the bradycardic activities of Acetyldigoxin.Experimental
Acetylsalicylic acidAcetylsalicylic acid may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
AdapaleneAdapalene may decrease the antihypertensive activities of Indenolol.Approved
AgmatineAgmatine may increase the atrioventricular blocking (AV block) activities of Indenolol.Experimental, Investigational
AlaproclateThe serum concentration of Indenolol can be increased when it is combined with Alaproclate.Experimental
AlclofenacAlclofenac may decrease the antihypertensive activities of Indenolol.Approved, Withdrawn
AlfentanilAlfentanil may increase the bradycardic activities of Indenolol.Approved, Illicit
AlfuzosinAlfuzosin may increase the hypotensive activities of Indenolol.Approved, Investigational
AlimemazineAlimemazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
AliskirenIndenolol may increase the hypotensive activities of Aliskiren.Approved, Investigational
AlminoprofenAlminoprofen may decrease the antihypertensive activities of Indenolol.Experimental
AlprenololAlprenolol may increase the hypotensive activities of Indenolol.Approved, Withdrawn
AmbenoniumAmbenonium may increase the bradycardic activities of Indenolol.Approved
AmbrisentanIndenolol may increase the hypotensive activities of Ambrisentan.Approved, Investigational
AmifostineIndenolol may increase the hypotensive activities of Amifostine.Approved, Investigational
AmiodaroneAmiodarone may increase the bradycardic activities of Indenolol.Approved, Investigational
AmlodipineAmlodipine may increase the hypotensive activities of Indenolol.Approved
AmobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Amobarbital.Approved, Illicit
AmodiaquineThe metabolism of Indenolol can be decreased when combined with Amodiaquine.Approved, Investigational
AmphetamineAmphetamine may increase the hypotensive activities of Indenolol.Approved, Illicit
AndrographolideAndrographolide may decrease the antihypertensive activities of Indenolol.Investigational
AnisodamineAnisodamine may decrease the antihypertensive activities of Indenolol.Investigational
AntipyrineAntipyrine may decrease the antihypertensive activities of Indenolol.Approved
ApocyninApocynin may decrease the antihypertensive activities of Indenolol.Investigational
ApomorphineApomorphine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
ApremilastApremilast may decrease the antihypertensive activities of Indenolol.Approved, Investigational
ArecolineThe risk or severity of adverse effects can be increased when Indenolol is combined with Arecoline.Experimental
AtenololAtenolol may increase the hypotensive activities of Indenolol.Approved
AvanafilAvanafil may increase the antihypertensive activities of Indenolol.Approved
AzapropazoneAzapropazone may decrease the antihypertensive activities of Indenolol.Withdrawn
AzelastineAzelastine may decrease the antihypertensive activities of Indenolol.Approved
BalsalazideBalsalazide may decrease the antihypertensive activities of Indenolol.Approved, Investigational
BarbexacloneThe serum concentration of Indenolol can be decreased when it is combined with Barbexaclone.Experimental
BarbitalThe serum concentration of Indenolol can be decreased when it is combined with Barbital.Illicit
BenazeprilBenazepril may increase the hypotensive activities of Indenolol.Approved, Investigational
BendazacBendazac may decrease the antihypertensive activities of Indenolol.Experimental
BendroflumethiazideBendroflumethiazide may increase the hypotensive activities of Indenolol.Approved
BenmoxinBenmoxin may increase the hypotensive activities of Indenolol.Withdrawn
BenorilateBenorilate may decrease the antihypertensive activities of Indenolol.Experimental
BenoxaprofenBenoxaprofen may decrease the antihypertensive activities of Indenolol.Withdrawn
BenzphetamineBenzphetamine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Illicit
BenzydamineBenzydamine may decrease the antihypertensive activities of Indenolol.Approved
BepridilBepridil may increase the hypotensive activities of Indenolol.Approved, Withdrawn
BetaxololBetaxolol may increase the hypotensive activities of Indenolol.Approved
BethanecholThe risk or severity of adverse effects can be increased when Indenolol is combined with Bethanechol.Approved
BethanidineBethanidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
BevoniumBevonium may decrease the antihypertensive activities of Indenolol.Experimental
BietaserpineBietaserpine may increase the hypotensive activities of Indenolol.Experimental
BimatoprostBimatoprost may increase the hypotensive activities of Indenolol.Approved, Investigational
BisoprololBisoprolol may increase the hypotensive activities of Indenolol.Approved
BL-1020BL-1020 may increase the hypotensive activities of Indenolol.Investigational
BosentanBosentan may increase the hypotensive activities of Indenolol.Approved, Investigational
BQ-123Indenolol may increase the hypotensive activities of BQ-123.Investigational
BretyliumBretylium may increase the hypotensive activities of Indenolol.Approved
BrimonidineBrimonidine may increase the antihypertensive activities of Indenolol.Approved
BrofaromineBrofaromine may increase the hypotensive activities of Indenolol.Experimental
BromfenacBromfenac may decrease the antihypertensive activities of Indenolol.Approved
BromocriptineBromocriptine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
BucillamineBucillamine may decrease the antihypertensive activities of Indenolol.Investigational
BucindololIndenolol may increase the orthostatic hypotensive activities of Bucindolol.Investigational
BufexamacBufexamac may decrease the antihypertensive activities of Indenolol.Experimental
BumadizoneBumadizone may decrease the antihypertensive activities of Indenolol.Experimental
BunazosinIndenolol may increase the orthostatic hypotensive activities of Bunazosin.Investigational
BupivacaineThe serum concentration of Bupivacaine can be increased when it is combined with Indenolol.Approved, Investigational
BupranololBupranolol may increase the hypotensive activities of Indenolol.Approved
CabergolineIndenolol may increase the vasoconstricting activities of Cabergoline.Approved
CadralazineCadralazine may increase the hypotensive activities of Indenolol.Experimental
CafedrineIndenolol may increase the hypotensive activities of Cafedrine.Investigational
CandesartanIndenolol may increase the hypotensive activities of Candesartan.Experimental
Candesartan cilexetilCandesartan cilexetil may increase the hypotensive activities of Indenolol.Approved
CandoxatrilCandoxatril may increase the hypotensive activities of Indenolol.Experimental
CaptoprilCaptopril may increase the hypotensive activities of Indenolol.Approved
CarbacholThe risk or severity of adverse effects can be increased when Indenolol is combined with Carbachol.Approved
CarbutamideIndenolol may increase the hypoglycemic activities of Carbutamide.Experimental
CaroxazoneCaroxazone may increase the hypotensive activities of Indenolol.Withdrawn
CarprofenCarprofen may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved, Withdrawn
CarteololCarteolol may increase the hypotensive activities of Indenolol.Approved
CarvedilolIndenolol may increase the orthostatic hypotensive activities of Carvedilol.Approved, Investigational
CastanospermineCastanospermine may decrease the antihypertensive activities of Indenolol.Experimental
CelecoxibCelecoxib may decrease the antihypertensive activities of Indenolol.Approved, Investigational
CeliprololCeliprolol may increase the hypotensive activities of Indenolol.Approved, Investigational
CevimelineThe risk or severity of adverse effects can be increased when Indenolol is combined with Cevimeline.Approved
ChloroquineThe metabolism of Indenolol can be decreased when combined with Chloroquine.Approved, Vet Approved
ChlorothiazideChlorothiazide may increase the hypotensive activities of Indenolol.Approved, Vet Approved
ChlorproethazineChlorproethazine may increase the hypotensive activities of Indenolol.Experimental
ChlorpromazineChlorpromazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
ChlorpropamideIndenolol may increase the hypoglycemic activities of Chlorpropamide.Approved
ChlorthalidoneChlorthalidone may increase the hypotensive activities of Indenolol.Approved
Choline magnesium trisalicylateCholine magnesium trisalicylate may decrease the antihypertensive activities of Indenolol.Approved
CicletanineIndenolol may increase the hypotensive activities of Cicletanine.Investigational
CilazaprilCilazapril may increase the hypotensive activities of Indenolol.Approved
ClonidineClonidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
ClonixinClonixin may decrease the antihypertensive activities of Indenolol.Approved
CloranololIndenolol may increase the hypotensive activities of Cloranolol.Experimental
CoumaphosCoumaphos may increase the bradycardic activities of Indenolol.Vet Approved
CryptenamineCryptenamine may increase the hypotensive activities of Indenolol.Approved
CurcuminCurcumin may decrease the antihypertensive activities of Indenolol.Investigational
CyclopenthiazideIndenolol may increase the hypotensive activities of Cyclopenthiazide.Experimental
CyclothiazideCyclothiazide may increase the hypotensive activities of Indenolol.Approved
CymarinIndenolol may increase the bradycardic activities of Cymarin.Experimental
D-LimoneneD-Limonene may decrease the antihypertensive activities of Indenolol.Investigational
DapoxetineThe serum concentration of Indenolol can be increased when it is combined with Dapoxetine.Investigational
DebrisoquinDebrisoquin may increase the hypotensive activities of Indenolol.Approved, Investigational
DecamethoniumDecamethonium may increase the bradycardic activities of Indenolol.Approved
DelaprilIndenolol may increase the hypotensive activities of Delapril.Experimental
DemecariumDemecarium may increase the bradycardic activities of Indenolol.Approved
DeserpidineIndenolol may increase the hypotensive activities of Deserpidine.Approved
DeslanosideIndenolol may increase the bradycardic activities of Deslanoside.Approved
DesvenlafaxineThe serum concentration of Indenolol can be increased when it is combined with Desvenlafaxine.Approved
DexmedetomidineDexmedetomidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Vet Approved
DiazoxideDiazoxide may increase the hypotensive activities of Indenolol.Approved
DichlorvosDichlorvos may increase the bradycardic activities of Indenolol.Vet Approved
DiclofenacDiclofenac may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
diethylnorsperminediethylnorspermine may increase the hypotensive activities of Indenolol.Investigational
DifenpiramideDifenpiramide may decrease the antihypertensive activities of Indenolol.Experimental
DiflunisalDiflunisal may decrease the antihypertensive activities of Indenolol.Approved
DigitoxinIndenolol may increase the bradycardic activities of Digitoxin.Approved, Investigational
DigoxinIndenolol may increase the bradycardic activities of Digoxin.Approved
Digoxin Immune Fab (Ovine)Indenolol may increase the bradycardic activities of Digoxin Immune Fab (Ovine).Approved
DihydralazineDihydralazine may increase the hypotensive activities of Indenolol.Investigational
DihydroergotamineDihydroergotamine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
DiltiazemDiltiazem may increase the hypotensive activities of Indenolol.Approved
DipivefrinDipivefrin may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
DipyridamoleDipyridamole may increase the bradycardic activities of Indenolol.Approved
DisopyramideDisopyramide may increase the bradycardic activities of Indenolol.Approved
DistigmineDistigmine may increase the bradycardic activities of Indenolol.Experimental
DonepezilDonepezil may increase the bradycardic activities of Indenolol.Approved
DorzolamideDorzolamide may increase the hypotensive activities of Indenolol.Approved
DoxazosinIndenolol may increase the orthostatic hypotensive activities of Doxazosin.Approved
DronedaroneDronedarone may increase the bradycardic activities of Indenolol.Approved
DroxicamDroxicam may decrease the antihypertensive activities of Indenolol.Approved
DroxidopaDroxidopa may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
DuloxetineThe serum concentration of Indenolol can be increased when it is combined with Duloxetine.Approved
DuvelisibDuvelisib may decrease the antihypertensive activities of Indenolol.Investigational
E-6201E-6201 may decrease the antihypertensive activities of Indenolol.Investigational
EchothiophateEchothiophate may increase the bradycardic activities of Indenolol.Approved
EdrophoniumEdrophonium may increase the bradycardic activities of Indenolol.Approved
EfonidipineIndenolol may increase the hypotensive activities of Efonidipine.Approved, Investigational
EnalaprilEnalapril may increase the hypotensive activities of Indenolol.Approved, Vet Approved
EnalaprilatIndenolol may increase the hypotensive activities of Enalaprilat.Approved
EndralazineEndralazine may increase the hypotensive activities of Indenolol.Experimental
EpanololIndenolol may increase the hypotensive activities of Epanolol.Experimental
EphedraEphedra may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Nutraceutical, Withdrawn
EpibatidineThe risk or severity of adverse effects can be increased when Indenolol is combined with Epibatidine.Experimental
EpinephrineEpinephrine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Vet Approved
EpirizoleEpirizole may decrease the antihypertensive activities of Indenolol.Approved
EpoprostenolEpoprostenol may increase the hypotensive activities of Indenolol.Approved
EprosartanEprosartan may increase the hypotensive activities of Indenolol.Approved
Ergoloid mesylateIndenolol may increase the vasoconstricting activities of Ergoloid mesylate.Approved
ErgonovineIndenolol may increase the vasoconstricting activities of Ergonovine.Approved
ErgotamineErgotamine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
EtanerceptEtanercept may decrease the antihypertensive activities of Indenolol.Approved, Investigational
EthenzamideEthenzamide may decrease the antihypertensive activities of Indenolol.Experimental
EtodolacEtodolac may decrease the antihypertensive activities of Indenolol.Approved, Investigational, Vet Approved
EtofenamateEtofenamate may decrease the antihypertensive activities of Indenolol.Approved, Investigational
EtomidateEtomidate may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
EtoperidoneThe serum concentration of Indenolol can be increased when it is combined with Etoperidone.Withdrawn
EtoricoxibEtoricoxib may decrease the antihypertensive activities of Indenolol.Approved, Investigational
Evening primrose oilEvening primrose oil may decrease the antihypertensive activities of Indenolol.Approved, Investigational
exisulindexisulind may decrease the antihypertensive activities of Indenolol.Investigational
FelbinacFelbinac may decrease the antihypertensive activities of Indenolol.Experimental
FelodipineFelodipine may increase the hypotensive activities of Indenolol.Approved, Investigational
FenbufenFenbufen may decrease the antihypertensive activities of Indenolol.Approved
FenoldopamFenoldopam may increase the hypotensive activities of Indenolol.Approved
FenoprofenFenoprofen may decrease the antihypertensive activities of Indenolol.Approved
FentanylFentanyl may increase the bradycardic activities of Indenolol.Approved, Illicit, Investigational, Vet Approved
FenthionFenthion may increase the bradycardic activities of Indenolol.Vet Approved
FentiazacFentiazac may decrease the antihypertensive activities of Indenolol.Experimental
FeprazoneFeprazone may decrease the antihypertensive activities of Indenolol.Experimental
Ferulic acidFerulic acid may increase the hypotensive activities of Indenolol.Experimental
FingolimodIndenolol may increase the bradycardic activities of Fingolimod.Approved, Investigational
FloctafenineThe risk or severity of adverse effects can be increased when Indenolol is combined with Floctafenine.Approved, Withdrawn
FlunixinFlunixin may decrease the antihypertensive activities of Indenolol.Vet Approved
FlunoxaprofenFlunoxaprofen may decrease the antihypertensive activities of Indenolol.Experimental
FluoxetineThe serum concentration of Indenolol can be increased when it is combined with Fluoxetine.Approved, Vet Approved
FluphenazineFluphenazine may increase the hypotensive activities of Indenolol.Approved
FlurbiprofenFlurbiprofen may decrease the antihypertensive activities of Indenolol.Approved, Investigational
FosinoprilFosinopril may increase the hypotensive activities of Indenolol.Approved
FurazolidoneFurazolidone may increase the hypotensive activities of Indenolol.Approved, Investigational, Vet Approved
GalantamineGalantamine may increase the bradycardic activities of Indenolol.Approved
Gallamine TriethiodideGallamine Triethiodide may increase the bradycardic activities of Indenolol.Approved
GitoformateIndenolol may increase the bradycardic activities of Gitoformate.Experimental
GlibornurideIndenolol may increase the hypoglycemic activities of Glibornuride.Investigational, Withdrawn
GliclazideIndenolol may increase the hypoglycemic activities of Gliclazide.Approved
GlimepirideIndenolol may increase the hypoglycemic activities of Glimepiride.Approved
GlipizideIndenolol may increase the hypoglycemic activities of Glipizide.Approved
GliquidoneIndenolol may increase the hypoglycemic activities of Gliquidone.Approved, Investigational
GlisoxepideIndenolol may increase the hypoglycemic activities of Glisoxepide.Approved, Investigational
GlyburideIndenolol may increase the hypoglycemic activities of Glyburide.Approved
GTS-21The risk or severity of adverse effects can be increased when Indenolol is combined with GTS-21.Investigational
GuacetisalGuacetisal may decrease the antihypertensive activities of Indenolol.Experimental
GuanabenzGuanabenz may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
GuanadrelGuanadrel may increase the hypotensive activities of Indenolol.Approved
GuanazodineIndenolol may increase the hypotensive activities of Guanazodine.Experimental
GuanethidineGuanethidine may increase the hypotensive activities of Indenolol.Approved
GuanfacineGuanfacine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
GuanoclorIndenolol may increase the hypotensive activities of Guanoclor.Experimental
GuanoxabenzIndenolol may increase the hypotensive activities of Guanoxabenz.Experimental
GuanoxanIndenolol may increase the hypotensive activities of Guanoxan.Experimental
HarmalineHarmaline may increase the hypotensive activities of Indenolol.Experimental
HexamethoniumIndenolol may increase the hypotensive activities of Hexamethonium.Experimental
HexobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Hexobarbital.Approved
HigenamineHigenamine may decrease the antihypertensive activities of Indenolol.Investigational
Huperzine AHuperzine A may increase the bradycardic activities of Indenolol.Investigational
HydracarbazineHydracarbazine may increase the hypotensive activities of Indenolol.Experimental
HydralazineHydralazine may increase the hypotensive activities of Indenolol.Approved
HydrochlorothiazideHydrochlorothiazide may increase the hypotensive activities of Indenolol.Approved, Vet Approved
HydroflumethiazideHydroflumethiazide may increase the hypotensive activities of Indenolol.Approved, Investigational
HydroxychloroquineThe metabolism of Indenolol can be decreased when combined with Hydroxychloroquine.Approved
IbuprofenIbuprofen may decrease the antihypertensive activities of Indenolol.Approved
IbuproxamIbuproxam may decrease the antihypertensive activities of Indenolol.Withdrawn
IcatibantIcatibant may decrease the antihypertensive activities of Indenolol.Approved
IloprostIloprost may increase the hypotensive activities of Indenolol.Approved, Investigational
ImidaprilIndenolol may increase the hypotensive activities of Imidapril.Investigational
Imidazole salicylateImidazole salicylate may decrease the antihypertensive activities of Indenolol.Experimental
IndalpineThe serum concentration of Indenolol can be increased when it is combined with Indalpine.Investigational, Withdrawn
IndapamideIndapamide may increase the hypotensive activities of Indenolol.Approved
IndobufenIndobufen may decrease the antihypertensive activities of Indenolol.Investigational
IndomethacinIndomethacin may decrease the antihypertensive activities of Indenolol.Approved, Investigational
IndoprofenIndoprofen may decrease the antihypertensive activities of Indenolol.Withdrawn
IndoraminIndenolol may increase the orthostatic hypotensive activities of Indoramin.Withdrawn
Insulin HumanIndenolol may increase the hypoglycemic activities of Insulin Human.Approved, Investigational
Insulin PorkIndenolol may increase the hypoglycemic activities of Insulin Pork.Approved
IpidacrineIpidacrine may increase the bradycardic activities of Indenolol.Experimental
IproclozideIproclozide may increase the hypotensive activities of Indenolol.Withdrawn
IproniazidIproniazid may increase the hypotensive activities of Indenolol.Withdrawn
IrbesartanIrbesartan may increase the hypotensive activities of Indenolol.Approved, Investigational
IsocarboxazidIsocarboxazid may increase the hypotensive activities of Indenolol.Approved
IsoflurophateIsoflurophate may increase the bradycardic activities of Indenolol.Approved, Investigational, Withdrawn
IsoxicamIsoxicam may decrease the antihypertensive activities of Indenolol.Withdrawn
IsradipineIsradipine may increase the hypotensive activities of Indenolol.Approved
KebuzoneKebuzone may decrease the antihypertensive activities of Indenolol.Experimental
KetanserinKetanserin may increase the hypotensive activities of Indenolol.Investigational
KetoprofenKetoprofen may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
KetorolacKetorolac may decrease the antihypertensive activities of Indenolol.Approved
LabetalolIndenolol may increase the orthostatic hypotensive activities of Labetalol.Approved
LacidipineIndenolol may increase the hypotensive activities of Lacidipine.Approved, Investigational
Lanatoside CIndenolol may increase the bradycardic activities of Lanatoside C.Experimental
LatanoprostLatanoprost may increase the hypotensive activities of Indenolol.Approved, Investigational
LeflunomideLeflunomide may decrease the antihypertensive activities of Indenolol.Approved, Investigational
LercanidipineLercanidipine may increase the hypotensive activities of Indenolol.Approved, Investigational
LevomilnacipranThe serum concentration of Indenolol can be increased when it is combined with Levomilnacipran.Approved
LevonordefrinLevonordefrin may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
LidocaineThe serum concentration of Lidocaine can be increased when it is combined with Indenolol.Approved, Vet Approved
LinsidomineIndenolol may increase the hypotensive activities of Linsidomine.Experimental
LisinoprilLisinopril may increase the hypotensive activities of Indenolol.Approved, Investigational
LisofyllineLisofylline may decrease the antihypertensive activities of Indenolol.Investigational
LobelineThe risk or severity of adverse effects can be increased when Indenolol is combined with Lobeline.Investigational
LofexidineLofexidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
LonazolacLonazolac may decrease the antihypertensive activities of Indenolol.Experimental
LornoxicamLornoxicam may decrease the antihypertensive activities of Indenolol.Approved, Investigational
LosartanLosartan may increase the hypotensive activities of Indenolol.Approved
LoxoprofenLoxoprofen may decrease the antihypertensive activities of Indenolol.Approved, Investigational
LumiracoxibLumiracoxib may decrease the antihypertensive activities of Indenolol.Approved, Investigational
MacitentanIndenolol may increase the hypotensive activities of Macitentan.Approved
Magnesium salicylateMagnesium salicylate may decrease the antihypertensive activities of Indenolol.Approved
MalathionMalathion may increase the bradycardic activities of Indenolol.Approved, Investigational
ManidipineIndenolol may increase the hypotensive activities of Manidipine.Approved, Investigational
MasoprocolMasoprocol may decrease the antihypertensive activities of Indenolol.Approved, Investigational
MebanazineMebanazine may increase the hypotensive activities of Indenolol.Withdrawn
MecamylamineMecamylamine may increase the hypotensive activities of Indenolol.Approved
Meclofenamic acidMeclofenamic acid may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
Mefenamic acidMefenamic acid may decrease the antihypertensive activities of Indenolol.Approved
MefloquineMefloquine may increase the bradycardic activities of Indenolol.Approved
MeloxicamMeloxicam may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
MemantineMemantine may increase the bradycardic activities of Indenolol.Approved, Investigational
MepivacaineThe serum concentration of Mepivacaine can be increased when it is combined with Indenolol.Approved, Vet Approved
MesalazineMesalazine may decrease the antihypertensive activities of Indenolol.Approved
MesoridazineMesoridazine may increase the hypotensive activities of Indenolol.Approved, Investigational
MetahexamideIndenolol may increase the hypoglycemic activities of Metahexamide.Experimental
MetamizoleMetamizole may decrease the antihypertensive activities of Indenolol.Investigational, Withdrawn
MethacholineIndenolol may increase the bronchoconstrictory activities of Methacholine.Approved
MethamphetamineMethamphetamine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Illicit
Methanesulfonyl FluorideMethanesulfonyl Fluoride may increase the bradycardic activities of Indenolol.Investigational
MethohexitalThe serum concentration of Indenolol can be decreased when it is combined with Methohexital.Approved
MethoserpidineIndenolol may increase the hypotensive activities of Methoserpidine.Experimental
MethotrimeprazineMethotrimeprazine may increase the hypotensive activities of Indenolol.Approved
MethyldopaMethyldopa may increase the hypotensive activities of Indenolol.Approved
Methylene blueMethylene blue may increase the hypotensive activities of Indenolol.Approved, Investigational
MethylergometrineIndenolol may increase the vasoconstricting activities of Methylergometrine.Approved
MethylphenidateMethylphenidate may decrease the antihypertensive activities of Indenolol.Approved, Investigational
MethylphenobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Methylphenobarbital.Approved
MetildigoxinIndenolol may increase the bradycardic activities of Metildigoxin.Experimental
MetipranololMetipranolol may increase the hypotensive activities of Indenolol.Approved
MetoclopramideMetoclopramide may increase the bradycardic activities of Indenolol.Approved, Investigational
MetolazoneMetolazone may increase the hypotensive activities of Indenolol.Approved
MetoprololMetoprolol may increase the hypotensive activities of Indenolol.Approved, Investigational
MetyrosineIndenolol may increase the hypotensive activities of Metyrosine.Approved
MibefradilMibefradil may increase the hypotensive activities of Indenolol.Investigational, Withdrawn
MidodrineIndenolol may increase the bradycardic activities of Midodrine.Approved
MilnacipranThe serum concentration of Indenolol can be increased when it is combined with Milnacipran.Approved
MinaprineMinaprine may increase the bradycardic activities of Indenolol.Approved
MinoxidilMinoxidil may increase the hypotensive activities of Indenolol.Approved
MirodenafilMirodenafil may increase the antihypertensive activities of Indenolol.Investigational
MizoribineMizoribine may decrease the antihypertensive activities of Indenolol.Investigational
MoclobemideMoclobemide may increase the hypotensive activities of Indenolol.Approved
MoexiprilMoexipril may increase the hypotensive activities of Indenolol.Approved
MofebutazoneMofebutazone may decrease the antihypertensive activities of Indenolol.Experimental
MolsidomineMolsidomine may increase the hypotensive activities of Indenolol.Approved, Investigational
MoricizineMoricizine may increase the hypotensive activities of Indenolol.Approved, Investigational, Withdrawn
MoxonidineMoxonidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
MuzolimineIndenolol may increase the hypotensive activities of Muzolimine.Experimental
Mycophenolate mofetilMycophenolate mofetil may decrease the antihypertensive activities of Indenolol.Approved, Investigational
Mycophenolic acidMycophenolic acid may decrease the antihypertensive activities of Indenolol.Approved
NabumetoneNabumetone may decrease the antihypertensive activities of Indenolol.Approved
NadololNadolol may increase the hypotensive activities of Indenolol.Approved
NafamostatNafamostat may decrease the antihypertensive activities of Indenolol.Approved, Investigational
NaftifineNaftifine may decrease the antihypertensive activities of Indenolol.Approved
NaftopidilIndenolol may increase the hypotensive activities of Naftopidil.Investigational
NaphazolineNaphazoline may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
NaproxenNaproxen may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
NebivololNebivolol may increase the hypotensive activities of Indenolol.Approved, Investigational
NefazodoneThe serum concentration of Indenolol can be increased when it is combined with Nefazodone.Approved, Withdrawn
NeostigmineNeostigmine may increase the bradycardic activities of Indenolol.Approved, Vet Approved
NepafenacNepafenac may decrease the antihypertensive activities of Indenolol.Approved
NialamideNialamide may increase the hypotensive activities of Indenolol.Withdrawn
NicardipineNicardipine may increase the hypotensive activities of Indenolol.Approved
NicorandilIndenolol may increase the hypotensive activities of Nicorandil.Approved, Investigational
NicotineThe risk or severity of adverse effects can be increased when Indenolol is combined with Nicotine.Approved
NifedipineNifedipine may increase the hypotensive activities of Indenolol.Approved
NifenazoneNifenazone may decrease the antihypertensive activities of Indenolol.Experimental
Niflumic AcidNiflumic Acid may decrease the antihypertensive activities of Indenolol.Approved
NiguldipineIndenolol may increase the hypotensive activities of Niguldipine.Experimental
NilvadipineNilvadipine may increase the hypotensive activities of Indenolol.Approved, Investigational
NimesulideNimesulide may decrease the antihypertensive activities of Indenolol.Approved, Investigational, Withdrawn
NimodipineNimodipine may increase the hypotensive activities of Indenolol.Approved
NisoldipineNisoldipine may increase the hypotensive activities of Indenolol.Approved
NitrendipineNitrendipine may increase the hypotensive activities of Indenolol.Approved, Investigational
NitroaspirinNitroaspirin may decrease the antihypertensive activities of Indenolol.Investigational
NitroprussideNitroprusside may increase the hypotensive activities of Indenolol.Approved
NorepinephrineNorepinephrine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
ObinutuzumabIndenolol may increase the hypotensive activities of Obinutuzumab.Approved
OctamoxinOctamoxin may increase the hypotensive activities of Indenolol.Withdrawn
OleandrinIndenolol may increase the bradycardic activities of Oleandrin.Experimental, Investigational
OlmesartanOlmesartan may increase the hypotensive activities of Indenolol.Approved, Investigational
OlopatadineOlopatadine may decrease the antihypertensive activities of Indenolol.Approved
OlsalazineOlsalazine may decrease the antihypertensive activities of Indenolol.Approved
OmapatrilatOmapatrilat may increase the hypotensive activities of Indenolol.Investigational
OrgoteinOrgotein may decrease the antihypertensive activities of Indenolol.Vet Approved
OuabainIndenolol may increase the bradycardic activities of Ouabain.Approved
OxaprozinOxaprozin may decrease the antihypertensive activities of Indenolol.Approved
OxprenololOxprenolol may increase the hypotensive activities of Indenolol.Approved
OxymetazolineOxymetazoline may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
OxyphenbutazoneOxyphenbutazone may decrease the antihypertensive activities of Indenolol.Approved, Withdrawn
PaliperidonePaliperidone may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
ParaoxonParaoxon may increase the bradycardic activities of Indenolol.Experimental
ParecoxibParecoxib may decrease the antihypertensive activities of Indenolol.Approved
PargylinePargyline may increase the hypotensive activities of Indenolol.Approved
ParoxetineThe serum concentration of Indenolol can be increased when it is combined with Paroxetine.Approved, Investigational
ParthenolideParthenolide may decrease the antihypertensive activities of Indenolol.Investigational
PenbutololPenbutolol may increase the hypotensive activities of Indenolol.Approved, Investigational
PentobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Pentobarbital.Approved, Vet Approved
PentoliniumPentolinium may increase the hypotensive activities of Indenolol.Approved
PentoxifyllinePentoxifylline may increase the hypotensive activities of Indenolol.Approved, Investigational
PerazinePerazine may increase the hypotensive activities of Indenolol.Investigational
PergolidePergolide may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational, Vet Approved, Withdrawn
PerindoprilPerindopril may increase the hypotensive activities of Indenolol.Approved
PerphenazinePerphenazine may increase the hypotensive activities of Indenolol.Approved
PeruvosideIndenolol may increase the bradycardic activities of Peruvoside.Experimental
PhenelzinePhenelzine may increase the hypotensive activities of Indenolol.Approved
PheniprazinePheniprazine may increase the hypotensive activities of Indenolol.Withdrawn
PhenobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Phenobarbital.Approved
PhenoxybenzaminePhenoxybenzamine may increase the hypotensive activities of Indenolol.Approved
PhenoxypropazinePhenoxypropazine may increase the hypotensive activities of Indenolol.Withdrawn
PhentolaminePhentolamine may increase the hypotensive activities of Indenolol.Approved
PhenylbutazonePhenylbutazone may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
PhysostigminePhysostigmine may increase the bradycardic activities of Indenolol.Approved
PilocarpineThe risk or severity of adverse effects can be increased when Indenolol is combined with Pilocarpine.Approved
PimecrolimusPimecrolimus may decrease the antihypertensive activities of Indenolol.Approved, Investigational
PinacidilPinacidil may increase the hypotensive activities of Indenolol.Withdrawn
PindololPindolol may increase the hypotensive activities of Indenolol.Approved
PirfenidonePirfenidone may decrease the antihypertensive activities of Indenolol.Approved, Investigational
PirlindolePirlindole may increase the hypotensive activities of Indenolol.Approved
PiroxicamPiroxicam may decrease the antihypertensive activities of Indenolol.Approved, Investigational
PirprofenPirprofen may decrease the antihypertensive activities of Indenolol.Experimental
PivhydrazinePivhydrazine may increase the hypotensive activities of Indenolol.Withdrawn
Platelet Activating FactorPlatelet Activating Factor may increase the hypotensive activities of Indenolol.Experimental
PolythiazidePolythiazide may increase the hypotensive activities of Indenolol.Approved
PranoprofenPranoprofen may decrease the antihypertensive activities of Indenolol.Experimental, Investigational
PrazosinIndenolol may increase the orthostatic hypotensive activities of Prazosin.Approved
PrimaquineThe metabolism of Indenolol can be decreased when combined with Primaquine.Approved
PrimidoneThe serum concentration of Indenolol can be decreased when it is combined with Primidone.Approved, Vet Approved
ProcarbazineProcarbazine may increase the hypotensive activities of Indenolol.Approved
ProchlorperazineProchlorperazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
ProglumetacinProglumetacin may decrease the antihypertensive activities of Indenolol.Experimental
PromazinePromazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
PromethazinePromethazine may increase the hypotensive activities of Indenolol.Approved
PropacetamolPropacetamol may decrease the antihypertensive activities of Indenolol.Approved, Investigational
PropafenoneThe serum concentration of Indenolol can be increased when it is combined with Propafenone.Approved
PropericiazinePropericiazine may increase the hypotensive activities of Indenolol.Approved
PropiopromazinePropiopromazine may increase the hypotensive activities of Indenolol.Vet Approved
PropranololPropranolol may increase the hypotensive activities of Indenolol.Approved, Investigational
PropyphenazonePropyphenazone may decrease the antihypertensive activities of Indenolol.Experimental
ProquazoneProquazone may decrease the antihypertensive activities of Indenolol.Experimental
ProscillaridinIndenolol may increase the bradycardic activities of Proscillaridin.Experimental
PseudoephedrinePseudoephedrine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
PTC299PTC299 may decrease the antihypertensive activities of Indenolol.Investigational
PyridostigminePyridostigmine may increase the bradycardic activities of Indenolol.Approved
QuinaprilQuinapril may increase the hypotensive activities of Indenolol.Approved, Investigational
QuinineQuinine may increase the hypotensive activities of Indenolol.Approved
RamiprilRamipril may increase the hypotensive activities of Indenolol.Approved
RasagilineRasagiline may increase the hypotensive activities of Indenolol.Approved
RegorafenibRegorafenib may increase the bradycardic activities of Indenolol.Approved
RemifentanilRemifentanil may increase the bradycardic activities of Indenolol.Approved
RemikirenRemikiren may increase the hypotensive activities of Indenolol.Approved
RescinnamineIndenolol may increase the hypotensive activities of Rescinnamine.Approved
ReserpineReserpine may increase the hypotensive activities of Indenolol.Approved, Investigational
ResveratrolResveratrol may decrease the antihypertensive activities of Indenolol.Approved, Experimental, Investigational
RifampicinThe serum concentration of Indenolol can be decreased when it is combined with Rifampicin.Approved
RifapentineThe serum concentration of Indenolol can be decreased when it is combined with Rifapentine.Approved
RifaximinThe serum concentration of Indenolol can be decreased when it is combined with Rifaximin.Approved, Investigational
RilmenidineRilmenidine may increase the hypotensive activities of Indenolol.Investigational
RiociguatIndenolol may increase the hypotensive activities of Riociguat.Approved
RisperidoneRisperidone may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
RituximabIndenolol may increase the hypotensive activities of Rituximab.Approved
RivastigmineIndenolol may increase the bradycardic activities of Rivastigmine.Approved, Investigational
RofecoxibRofecoxib may decrease the antihypertensive activities of Indenolol.Investigational, Withdrawn
RopiniroleRopinirole may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved, Investigational
SafrazineSafrazine may increase the hypotensive activities of Indenolol.Withdrawn
SalicylamideSalicylamide may decrease the antihypertensive activities of Indenolol.Approved
Salicylic acidSalicylic acid may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
SalsalateSalsalate may decrease the antihypertensive activities of Indenolol.Approved
SaprisartanSaprisartan may increase the hypotensive activities of Indenolol.Experimental
SecobarbitalThe serum concentration of Indenolol can be decreased when it is combined with Secobarbital.Approved, Vet Approved
SelegilineSelegiline may increase the hypotensive activities of Indenolol.Approved, Investigational, Vet Approved
SelexipagIndenolol may increase the hypotensive activities of Selexipag.Approved
SemapimodSemapimod may decrease the antihypertensive activities of Indenolol.Investigational
SeratrodastSeratrodast may decrease the antihypertensive activities of Indenolol.Approved
SerrapeptaseSerrapeptase may decrease the antihypertensive activities of Indenolol.Investigational
SertralineThe serum concentration of Indenolol can be increased when it is combined with Sertraline.Approved
SildenafilSildenafil may increase the antihypertensive activities of Indenolol.Approved, Investigational
SilodosinIndenolol may increase the orthostatic hypotensive activities of Silodosin.Approved
SitaxentanIndenolol may increase the hypotensive activities of Sitaxentan.Approved, Investigational, Withdrawn
SpiraprilSpirapril may increase the hypotensive activities of Indenolol.Approved
SRT501SRT501 may decrease the antihypertensive activities of Indenolol.Investigational
SufentanilSufentanil may increase the bradycardic activities of Indenolol.Approved, Investigational
SulfasalazineSulfasalazine may decrease the antihypertensive activities of Indenolol.Approved
SulindacSulindac may decrease the antihypertensive activities of Indenolol.Approved
SuprofenSuprofen may decrease the antihypertensive activities of Indenolol.Approved, Withdrawn
SuxibuzoneSuxibuzone may decrease the antihypertensive activities of Indenolol.Experimental
TacrineTacrine may increase the bradycardic activities of Indenolol.Investigational, Withdrawn
TadalafilTadalafil may increase the antihypertensive activities of Indenolol.Approved, Investigational
TalinololIndenolol may increase the hypotensive activities of Talinolol.Investigational
TamsulosinIndenolol may increase the orthostatic hypotensive activities of Tamsulosin.Approved, Investigational
TarenflurbilTarenflurbil may decrease the antihypertensive activities of Indenolol.Investigational
TelmisartanTelmisartan may increase the hypotensive activities of Indenolol.Approved, Investigational
TemocaprilTemocapril may increase the hypotensive activities of Indenolol.Experimental, Investigational
TenidapTenidap may decrease the antihypertensive activities of Indenolol.Experimental
TenoxicamTenoxicam may decrease the antihypertensive activities of Indenolol.Approved
TepoxalinTepoxalin may decrease the antihypertensive activities of Indenolol.Vet Approved
TerazosinIndenolol may increase the orthostatic hypotensive activities of Terazosin.Approved
TeriflunomideTeriflunomide may decrease the antihypertensive activities of Indenolol.Approved
TerlipressinTerlipressin may increase the hypotensive activities of Indenolol.Approved, Investigational
TetrahydropalmatineIndenolol may increase the hypotensive activities of Tetrahydropalmatine.Investigational
TheodrenalineIndenolol may increase the hypotensive activities of Theodrenaline.Investigational
ThiamylalThe serum concentration of Indenolol can be decreased when it is combined with Thiamylal.Approved, Vet Approved
ThiazinamThiazinam may increase the hypotensive activities of Indenolol.Experimental
ThiethylperazineThiethylperazine may increase the hypotensive activities of Indenolol.Withdrawn
ThiopentalThe serum concentration of Indenolol can be decreased when it is combined with Thiopental.Approved, Vet Approved
ThioproperazineThioproperazine may increase the hypotensive activities of Indenolol.Approved
ThioridazineThioridazine may increase the hypotensive activities of Indenolol.Approved, Withdrawn
Tiaprofenic acidTiaprofenic acid may decrease the antihypertensive activities of Indenolol.Approved
TiboloneIndenolol may increase the hypotensive activities of Tibolone.Approved, Investigational
TicrynafenTicrynafen may increase the hypotensive activities of Indenolol.Withdrawn
TimololTimolol may increase the hypotensive activities of Indenolol.Approved
TinoridineTinoridine may decrease the antihypertensive activities of Indenolol.Investigational
TizanidineTizanidine may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
TolazamideIndenolol may increase the hypoglycemic activities of Tolazamide.Approved
TolazolineTolazoline may increase the hypotensive activities of Indenolol.Approved, Vet Approved
TolbutamideIndenolol may increase the hypoglycemic activities of Tolbutamide.Approved
Tolfenamic AcidTolfenamic Acid may decrease the antihypertensive activities of Indenolol.Approved
TolmetinTolmetin may decrease the antihypertensive activities of Indenolol.Approved
TolonidineIndenolol may increase the hypotensive activities of Tolonidine.Experimental
ToloxatoneToloxatone may increase the hypotensive activities of Indenolol.Approved
TorasemideTorasemide may increase the hypotensive activities of Indenolol.Approved
TrandolaprilTrandolapril may increase the hypotensive activities of Indenolol.Approved
TranilastTranilast may decrease the antihypertensive activities of Indenolol.Approved, Investigational
Trans-2-PhenylcyclopropylamineTrans-2-Phenylcyclopropylamine may increase the hypotensive activities of Indenolol.Experimental
TranylcypromineTranylcypromine may increase the hypotensive activities of Indenolol.Approved
TravoprostTravoprost may increase the hypotensive activities of Indenolol.Approved
TreprostinilTreprostinil may increase the hypotensive activities of Indenolol.Approved, Investigational
TribenosideTribenoside may decrease the antihypertensive activities of Indenolol.Experimental
TrichlorfonTrichlorfon may increase the bradycardic activities of Indenolol.Vet Approved
TrichlormethiazideTrichlormethiazide may increase the hypotensive activities of Indenolol.Approved, Vet Approved
TrifluoperazineTrifluoperazine may increase the hypotensive activities of Indenolol.Approved
TriflupromazineTriflupromazine may increase the hypotensive activities of Indenolol.Approved, Vet Approved
TrimazosinIndenolol may increase the orthostatic hypotensive activities of Trimazosin.Experimental
TrimethaphanTrimethaphan may increase the hypotensive activities of Indenolol.Approved, Investigational
TriptolideTriptolide may decrease the antihypertensive activities of Indenolol.Investigational
TubocurarineTubocurarine may increase the bradycardic activities of Indenolol.Approved
UdenafilUdenafil may increase the antihypertensive activities of Indenolol.Approved, Investigational
UnoprostoneUnoprostone may increase the hypotensive activities of Indenolol.Approved
UrapidilIndenolol may increase the orthostatic hypotensive activities of Urapidil.Investigational
ValdecoxibValdecoxib may decrease the antihypertensive activities of Indenolol.Investigational, Withdrawn
ValsartanValsartan may increase the hypotensive activities of Indenolol.Approved, Investigational
VardenafilVardenafil may increase the antihypertensive activities of Indenolol.Approved
VareniclineThe risk or severity of adverse effects can be increased when Indenolol is combined with Varenicline.Approved, Investigational
VenlafaxineThe serum concentration of Indenolol can be increased when it is combined with Venlafaxine.Approved
VerapamilVerapamil may increase the hypotensive activities of Indenolol.Approved
VincamineIndenolol may increase the hypotensive activities of Vincamine.Experimental
VinpocetineIndenolol may increase the hypotensive activities of Vinpocetine.Investigational
XipamideIndenolol may increase the hypotensive activities of Xipamide.Experimental
XylometazolineXylometazoline may increase the atrioventricular blocking (AV block) activities of Indenolol.Approved
YohimbineYohimbine may decrease the antihypertensive activities of Indenolol.Approved, Vet Approved
ZaltoprofenZaltoprofen may decrease the antihypertensive activities of Indenolol.Approved, Investigational
ZileutonZileuton may decrease the antihypertensive activities of Indenolol.Approved, Investigational, Withdrawn
ZimelidineThe serum concentration of Indenolol can be increased when it is combined with Zimelidine.Withdrawn
ZofenoprilIndenolol may increase the hypotensive activities of Zofenopril.Experimental
ZomepiracZomepirac may decrease the antihypertensive activities of Indenolol.Withdrawn
Food Interactions
Not Available

References

Synthesis Reference

U.S. Patent 4,045,482.

General References
  1. Ali I, Gaitonde VD, Aboul-Enein HY, Hussain A: Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC. Talanta. 2009 Apr 30;78(2):458-63. doi: 10.1016/j.talanta.2008.11.043. Epub 2008 Dec 6. [PubMed:19203609]
External Links
KEGG Drug
D08078
PubChem Compound
71955
PubChem Substance
310264917
ChemSpider
64962
ChEMBL
CHEMBL153585
Wikipedia
Indenolol

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)147-148U.S. Patent 4,045,482.
Predicted Properties
PropertyValueSource
Water Solubility0.277 mg/mLALOGPS
logP2.53ALOGPS
logP2.32ChemAxon
logS-3ALOGPS
pKa (Strongest Acidic)14.09ChemAxon
pKa (Strongest Basic)9.67ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area41.49 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity74.37 m3·mol-1ChemAxon
Polarizability28.66 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as indenes and isoindenes. These are compounds containing an indene moiety(which consists of a cyclopentadiene fused to a benzene ring), or a isoindene moiety (which consists of a cyclopentadiene fused to cyclohexadiene ring).
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Indenes and isoindenes
Sub Class
Not Available
Direct Parent
Indenes and isoindenes
Alternative Parents
Alkyl aryl ethers / Secondary alcohols / 1,2-aminoalcohols / Dialkylamines / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
Indene / Alkyl aryl ether / 1,2-aminoalcohol / Secondary alcohol / Secondary aliphatic amine / Ether / Secondary amine / Organic nitrogen compound / Organonitrogen compound / Organooxygen compound
Molecular Framework
Aromatic homopolycyclic compounds
External Descriptors
Not Available

Drug created on May 27, 2014 13:44 / Updated on December 01, 2017 16:11