Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
DrugDrug NameDrug Indication
DB00206ReserpineFoe the treatment of hypertension
DB00217BethanidineFor the treatment of hypertension.
DB00325NitroprussideFor immediate reduction of blood pressure of patients in hypertensive crises, reduce bleeding during surgery, and for the treatment of acute congestive heart failure
DB00350MinoxidilFor the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
DB00457PrazosinFor treatment of hypertension, symptomatic benign prostatic hyperplasia, and severe congestive heart failure. May also be used alone or in combination with β-blockers in the preoperative management of signs and symptoms of pheochromocytoma.
DB00559BosentanUsed in the treatment of pulmonary arterial hypertension (PAH), to improve exercise ability and to decrease the rate of clinical worsening (in patients with WHO Class III or IV symptoms).
DB00575ClonidineMay be used as an adjunct in the treatment of hypertension, as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone, for differential diagnosis of pheochromocytoma in hypertensive patients, prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD).
DB00590DoxazosinFor treatment and management of mild to moderate hypertension and urinary obstruction symptoms caused by BPH.
DB00657MecamylamineFor the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
DB01018GuanfacineFor use alone or in combination with other classes of antihypertensive agents in the management of hypertension. Has also been used for the treatment of attention deficit hyperactivity disorder (ADHD) in pediatric patients.
DB01116TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
DB01119DiazoxideUsed parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
DB01170GuanethidineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
DB01275HydralazineFor the treatment of essential hypertension, alone or as an adjunct. Also for the management of severe hypertension when the drug cannot be given orally or when blood pressure must be lowered immediately, congestive heart failure (in combination with cardiac glycosides and diuretics and/or with isosorbide dinitrate), and hypertension secondary to pre-eclampsia/eclampsia.
DB01626PargylineFor the treatment of moderate to severe hypertension.
DB04840DebrisoquinFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
DB08950IndoraminNot Available
DB09206TrimazosinNot Available
DB09242MoxonidineFor the treatment of mild to moderate essential hypertension. Effective as most first-line antihypertensives when used as monotherapy. [A27137]
DB11738RilmenidineNot Available
DB12465KetanserinNot Available
DB12945DihydralazineNot Available
DB12661UrapidilNot Available
DB11362SelexipagSelexipag is indicated for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization.
DB11770TalinololNot Available
DB11783ImidaprilNot Available
DB12054BQ-123Not Available
DB12092NaftopidilNot Available
DB12093TetrahydropalmatineNot Available
DB12131VinpocetineNot Available
DB12766CicletanineNot Available
DB12926CafedrineNot Available
DB12927TheodrenalineNot Available
DB13166ZofenoprilNot Available
DB13374VincamineNot Available
DB13532CyclopenthiazideNot Available
DB00765MetyrosineFor use in the treatment of patients with pheochromocytoma, for preoperative preparation of patients for surgery, management of patients when surgery is contraindicated, and chronic treatment of patients with malignant pheochromocytoma.
DB01089DeserpidineFor the treatment of hypertension.
DB01180RescinnamineFor the treatment of hypertension.
DB06268SitaxentanInvestigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.
DB06403AmbrisentanAmbrisentan is indicated for treatment of idiopathic (‘primary’) pulmonary arterial hypertension (IPAH) and pulmonary arterial hypertension (PAH) associated with connective tissue disease in patients with WHO functional class II or III symptoms. In the United States of America, ambrisentan is also indicated in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.
DB08931RiociguatRiociguat is indicated for the treatment of adults with persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), (WHO Group 4) after surgical treatment, or inoperable CTEPH, to improve exercise capacity and WHO functional class. Riociguat is indicated for the treatment of adults with pulmonary arterial hypertension (PAH), (WHO Group 1), to improve exercise capacity, WHO functional class and to delay clinical worsening. Efficacy was shown in patients on Riociguat monotherapy or in combination with endothelin receptor antagonists or prostanoids. Studies establishing effectiveness included predominately patients with WHO functional class II–III and etiologies of idiopathic or heritable PAH (61%) or PAH associated with connective tissue diseases (25%).
DB08932MacitentanMacitentan is indicated for patients with pulmonary arterial hypertension.
DB00177ValsartanMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00178RamiprilFor the management of mild to severe hypertension. May be used to reduce cardiovascular mortality following myocardial infarction in hemodynamically stable individuals who develop clinical signs of congestive heart failure within a few days following myocardial infarction. To reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events. May be used to slow the progression of renal disease in individuals with hypertension, diabetes mellitus and microalubinuria or overt nephropathy.
DB00195BetaxololFor the management of hypertension.
DB00212RemikirenFor the treatment of hypertension and heart failure
DB00214TorasemideFor the treatment of edema associated with congestive heart failure, renal disease, or hepatic disease. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
DB00226GuanadrelUsed to treat and control hypertension.
DB00264MetoprololFor the management of acute myocardial infarction, angina pectoris, heart failure and mild to moderate hypertension. May be used to treat supraventricular and tachyarrhythmias and as prophylaxis for migraine headaches.
DB00270IsradipineFor the management of mild to moderate essential hypertension. It may be used alone or concurrently with thiazide-type diuretics.
DB00275OlmesartanFor the treatment of hypertension.
DB00287TravoprostOphthalmic solution used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB00310ChlorthalidoneFor management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
DB00335AtenololFor the management of hypertention and long-term management of patients with angina pectoris
DB00343DiltiazemFor the treatment of Hypertension
DB00373TimololIn its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma.
DB00374TreprostinilFor use as a continuous subcutaneous infusion or intravenous infusion (for those not able to tolerate a subcutaneous infusion) for the treatment of pulmonary arterial hypertension in patients with NYHA Class II-IV symptoms to diminish symptoms associated with exercise.
DB00381AmlodipineFor the treatment of hypertension and chronic stable angina.
DB00393NimodipineFor use as an adjunct to improve neurologic outcome following subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms by reducing the incidence and severity of ischemic deficits.
DB00401NisoldipineFor the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
DB00436BendroflumethiazideFor the treatment of high blood pressure and management of edema related to heart failure.
DB00484BrimonidineThe ophthalmic solution is indicated for patients with open-angle glaucoma or ocular hypertension to lower intraocular pressure. The topical gel is indicated for the treatment of persistent (nontransient) facial erythema of rosacea in adults 18 years or older.
DB00492FosinoprilFor treating mild to moderate hypertension, use as an adjunct in treating congestive heart failure, and may be used to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00519TrandolaprilFor the treatment of mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure (CHF), to improve survival following myocardial infarction (MI) in individuals who are hemodynamically stable and demonstrate symptoms of left ventricular systolic dysfunction or signs of CHF within a few days following acute MI, and to slow progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00521CarteololFor the treatment of intraocular hypertension and chronic open-angle glaucoma
DB00524MetolazoneFor the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.
DB00528LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
DB00542BenazeprilFor the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.
DB00571PropranololFor the prophylaxis of migraine.
DB00584EnalaprilFor the treatment of essential or renovascular hypertension and symptomatic congestive heart failure. It may be used alone or in combination with thiazide diuretics.
DB00598LabetalolFor the management of hypertension (alone or in combination with other classes of antihypertensive agents), as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency, for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia, and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures.
DB00606CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
DB00612BisoprololFor management of heart failure, angina pectoris, and mild to moderate hypertension and for secondary prevention of myocardial infarction (MI).
DB00616CandoxatrilNot Available
DB00622NicardipineUsed for the management of patients with chronic stable angina and for the treatment of hypertension.
DB00629GuanabenzFor management of High blood pressure
DB00654LatanoprostFor the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
DB00678LosartanMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00691MoexiprilFor the treatment of hypertension.
DB00692PhentolamineUsed as an aid for the diagnosis of pheochromocytoma, and may be administered immediately prior to or during pheochromocytomectomy to prevent or control paroxysmal hypertension resulting from anesthesia, stress, or operative manipulation of the tumor. Phentolamine has also been used to treat hypertensive crisis caused by sympathomimetic amines or catecholamine excess by certain foods or drugs in patients taking MAO inhibitors, or by clonidine withdrawal syndrome. Other indications include the prevention of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine, decrease in impedance to left ventricular ejection and the infarct size in patients with MI associated with left ventricular failure, treatment of erectile dysfunction through self-injection of small doses combined with papaverine hydrochloride into the corpus cavernosum, and as an adjunct to the management of cocaine overdose to reverse coronary vasoconstriction following use of oxygen, benzodiazepines,and nitroglycerin.
DB00722LisinoprilFor the treatment of hypertension and symptomatic congestive heart failure. May be used in conjunction with thrombolytic agents, aspirin and/or β-blockers to improve survival in hemodynamically stable individuals following myocardial infarction. May be used to slow the progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00774HydroflumethiazideUsed as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Also used in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
DB00785CryptenamineFor the treatment of hypertension.
DB00790PerindoprilFor the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.
DB00796CandesartanMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Candesartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00797TolazolineFor the treatment of pulmonary artery anomalies
DB00800FenoldopamFor the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.
DB00808IndapamideFor the treatment of hypertension, alone or in combination with other antihypertensive drugs, as well as for the treatment of salt and fluid retention associated with congestive heart failure or edema from pregnancy (appropriate only in the management of edema of pathologic origin during pregnancy when clearly needed). Also used for the management of edema as a result of various causes.
DB00866AlprenololFor the treatment of hypertension, angina, and arrhythmia
DB00869DorzolamideFor the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Also used prophylatically for the inhibition of perioperative IOP increase (before neodynium yttrium aluminum garnet laser posterior capsulotomy).
DB00876EprosartanFor the management of hypertension alone or in combination with other classes of antihypertensive agents. Also used as a first-line agent in the treatment of diabetic nephropathy, as well as a second-line agent in the treatment of congestive heart failure (only in those intolerant of ACE inhibitors).
DB00880ChlorothiazideChlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
DB00881QuinaprilFor the treatment of hypertension and as adjunct therapy in the treatment of congestive heart failure. May also be used to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00886OmapatrilatFor the treatment of hypertension.
DB00905BimatoprostFor the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB00925PhenoxybenzamineFor the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
DB00960PindololFor the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
DB00966TelmisartanUsed alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).
DB00968MethyldopaFor use in the treatment of hypertension.
DB00999HydrochlorothiazideFor the treatment of high blood pressure and management of edema.
DB01021TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
DB01023FelodipineFor the treatment of mild to moderate essential hypertension.
DB01029IrbesartanFor the treatment of hypertension, as well as diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. Irbesartan is also used as a second line agent in the treatment of congestive heart failure.
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01136CarvedilolFor the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.
DB01158BretyliumFor use in the prophylaxis and therapy of ventricular fibrillation. Also used in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia, that have failed to respond to adequate doses of a first-line antiarrhythmic agent, such as lidocaine.
DB01193AcebutololFor the management of hypertension and ventricular premature beats in adults.
DB01197CaptoprilFor the treatment of essential or renovascular hypertension (usually administered with other drugs, particularly thiazide diuretics). May be used to treat congestive heart failure in combination with other drugs (e.g. cardiac glycosides, diuretics, β-adrenergic blockers). May improve survival in patients with left ventricular dysfunction following myocardial infarction. May be used to treat nephropathy, including diabetic nephropathy.
DB01203NadololUsed in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension.
DB01214MetipranololIndicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma.
DB01240EpoprostenolFor the long-term intravenous treatment of primary pulmonary hypertension and pulmonary hypertension associated with the scleroderma spectrum of disease in NYHA Class III and Class IV patients who do not respond adequately to conventional therapy.
DB01244BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
DB01324PolythiazidePolythiazide is a thiazide diuretic used to decrease edema and decrease blood pressure.
DB01340CilazaprilCilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure.
DB01347SaprisartanSaprisartan is used in the treatment of hypertension and heart failure.
DB01348SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
DB01359PenbutololPenbutolol is indicated in the treatment of mild to moderate arterial hypertension. It may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity.
DB01388MibefradilFor the treatment of angina and high blood pressure.
DB01580OxprenololUsed in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
DB02638TerlipressinCommonly used to stop bleeding of varices in the food pipe (oesophagus).
DB04831TicrynafenFor the treatment of hypertension.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB04861NebivololFor the treatment of essential hypertension.
DB04948LofexidineInvestigated for use/treatment in addictions and substance abuse.
DB06694XylometazolineIt is used for treating nasal congestion and minor inflammation due to allergies or colds.
DB06712NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
DB06826UnoprostoneFor the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB07767Ferulic acidNot Available
DB08808BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
DB08836TemocaprilTemocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
DB08952IndenololNot Available
DB08960HexamethoniumNot Available
DB09026AliskirenFor the treatment of hypertension, to lower blood pressure.
DB09070TiboloneNot Available
DB09220NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
DB09235EfonidipineFor the treatment of hypertension.
DB09236LacidipineFor the treatment of hypertension.
DB09238ManidipineFor the treatment of hypertension.
DB09239NiguldipineNot Available
DB09477EnalaprilatEnalaprilat injection is indicated for the treatment of hypertension when oral therapy is not practical.
DrugDrug NameTargetType
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineMultidrug resistance protein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00217BethanidineAlpha-2 adrenergic receptorstarget
DB00217BethanidineATP-sensitive inward rectifier potassium channel 1target
DB00217BethanidineBeta adrenergic receptortarget
DB00325NitroprussideAtrial natriuretic peptide receptor 1target
DB00325NitroprussideCytochrome P450 1A1enzyme
DB00325NitroprussideCytochrome P450 1A2enzyme
DB00350MinoxidilATP-sensitive inward rectifier potassium channel 1target
DB00350MinoxidilProstaglandin G/H synthase 1target
DB00350MinoxidilRenintarget
DB00457PrazosinAlpha-1A adrenergic receptortarget
DB00457PrazosinAlpha-1B adrenergic receptortarget
DB00457PrazosinAlpha-1D adrenergic receptortarget
DB00457PrazosinPotassium voltage-gated channel subfamily H member 2target
DB00457PrazosinPotassium voltage-gated channel subfamily H member 6target
DB00457PrazosinPotassium voltage-gated channel subfamily H member 7target
DB00457PrazosinAlpha-1-acid glycoprotein 1carrier
DB00457PrazosinSolute carrier family 22 member 2transporter
DB00457PrazosinSolute carrier family 22 member 1transporter
DB00457PrazosinSolute carrier family 22 member 3transporter
DB00457PrazosinMultidrug resistance protein 1transporter
DB00457PrazosinATP-binding cassette sub-family G member 2transporter
DB00457PrazosinCytochrome P450 1A1enzyme
DB00457PrazosinAlpha-2A adrenergic receptortarget
DB00457PrazosinAlpha-2B adrenergic receptortarget
DB00559BosentanEndothelin B receptortarget
DB00559BosentanEndothelin-1 receptortarget
DB00559BosentanCytochrome P450 3A4enzyme
DB00559BosentanCytochrome P450 2C9enzyme
DB00559BosentanBile salt export pumptransporter
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 1transporter
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineMultidrug resistance protein 1transporter
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00590DoxazosinAlpha-1A adrenergic receptortarget
DB00590DoxazosinAlpha-1B adrenergic receptortarget
DB00590DoxazosinAlpha-1D adrenergic receptortarget
DB00590DoxazosinPotassium voltage-gated channel subfamily H member 2target
DB00590DoxazosinPotassium voltage-gated channel subfamily H member 6target
DB00590DoxazosinPotassium voltage-gated channel subfamily H member 7target
DB00590DoxazosinAlpha-1-acid glycoprotein 1carrier
DB00590DoxazosinMultidrug resistance protein 1transporter
DB00590DoxazosinCytochrome P450 2C19enzyme
DB00590DoxazosinCytochrome P450 2D6enzyme
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
DB00657MecamylamineNeuronal acetylcholine receptor subunit beta-2target
DB01018GuanfacineAlpha-2A adrenergic receptortarget
DB01018GuanfacineCytochrome P450 2C9enzyme
DB01018GuanfacineCytochrome P450 2C19enzyme
DB01018GuanfacineCytochrome P450 3A4enzyme
DB01018GuanfacineAlpha-2B adrenergic receptortarget
DB01116TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
DB01116TrimethaphanCholinesteraseenzyme
DB01119DiazoxideSolute carrier family 12 member 3target
DB01119DiazoxideCarbonic anhydrase 1target
DB01119DiazoxideCarbonic anhydrase 2target
DB01119DiazoxideCalcium-activated potassium channel subunit alpha-1target
DB01119DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DB01119DiazoxideATP-sensitive inward rectifier potassium channel 11target
DB01119DiazoxideGlutamine synthetaseenzyme
DB01170GuanethidineSodium-dependent noradrenaline transportertarget
DB01170GuanethidineCytochrome P450 3A4enzyme
DB01275HydralazineMembrane primary amine oxidasetarget
DB01275HydralazineProlyl 4-hydroxylase subunit alpha-1target
DB01275HydralazineCytochrome P450 3A4enzyme
DB01626PargylineAmine oxidase [flavin-containing] Btarget
DB01626PargylineAmine oxidase [flavin-containing] Atarget
DB04840DebrisoquinSodium-dependent noradrenaline transportertarget
DB04840DebrisoquinCytochrome P450 2D6enzyme
DB04840DebrisoquinMultidrug resistance protein 1transporter
DB04840DebrisoquinCytochrome P450 1A1enzyme
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB09242MoxonidineNischarintarget
DB09242MoxonidineAlpha-2A adrenergic receptortarget
DB11738RilmenidineAlpha-2A adrenergic receptortarget
DB12465Ketanserin5-hydroxytryptamine receptor 2Atarget
DB11362SelexipagProstacyclin receptortarget
DB11362SelexipagLiver carboxylesterase 1enzyme
DB11362SelexipagCytochrome P450 2C8enzyme
DB11362SelexipagCytochrome P450 3A4enzyme
DB11362SelexipagSolute carrier organic anion transporter family member 1B1transporter
DB11362SelexipagSolute carrier organic anion transporter family member 1B3transporter
DB11362SelexipagMultidrug resistance protein 1transporter
DB12093TetrahydropalmatineD(1A) dopamine receptortarget
DB12093TetrahydropalmatineD(2) dopamine receptortarget
DB13166ZofenoprilAngiotensin-converting enzymetarget
DB00765MetyrosineTyrosine 3-monooxygenasetarget
DB01089DeserpidineSynaptic vesicular amine transportertarget
DB01180RescinnamineAngiotensin-converting enzymetarget
DB06268SitaxentanCytochrome P450 2C19enzyme
DB06268SitaxentanCytochrome P450 2C9enzyme
DB06268SitaxentanCytochrome P450 3A4enzyme
DB06268SitaxentanEndothelin-1 receptortarget
DB06268SitaxentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin-1 receptortarget
DB06403AmbrisentanCytochrome P450 2C19enzyme
DB06403AmbrisentanCytochrome P450 3A4enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
DB06403AmbrisentanMultidrug resistance protein 1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
DB06403AmbrisentanCytochrome P450 3A5enzyme
DB08931RiociguatSerum albumincarrier
DB08931RiociguatAlpha-1-acid glycoprotein 1carrier
DB08931RiociguatGuanylate cyclase soluble subunit alpha-2target
DB08931RiociguatATP-binding cassette sub-family G member 2transporter
DB08931RiociguatCytochrome P450 1A1enzyme
DB08931RiociguatCytochrome P450 3A4enzyme
DB08931RiociguatCytochrome P450 2C8enzyme
DB08931RiociguatCytochrome P450 2J2enzyme
DB08932MacitentanCytochrome P450 3A4enzyme
DB08932MacitentanCytochrome P450 2C19enzyme
DB08932MacitentanEndothelin-1 receptortarget
DB08932MacitentanEndothelin B receptortarget
DB08932MacitentanSerum albumincarrier
DB00177ValsartanType-1 angiotensin II receptortarget
DB00177ValsartanCytochrome P450 2C9enzyme
DB00177ValsartanSolute carrier organic anion transporter family member 1B3transporter
DB00177ValsartanSolute carrier organic anion transporter family member 1B1transporter
DB00177ValsartanSerum albumincarrier
DB00178RamiprilAngiotensin-converting enzymetarget
DB00178RamiprilSolute carrier family 15 member 1transporter
DB00178RamiprilSolute carrier family 15 member 2transporter
DB00178RamiprilCholinesteraseenzyme
DB00178RamiprilB1 bradykinin receptortarget
DB00195BetaxololBeta-1 adrenergic receptortarget
DB00195BetaxololBeta-2 adrenergic receptortarget
DB00195BetaxololCytochrome P450 1A2enzyme
DB00195BetaxololCytochrome P450 2D6enzyme
DB00212RemikirenRenintarget
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideProstaglandin G/H synthase 1enzyme
DB00214TorasemideCytochrome P450 2C19enzyme
DB00226GuanadrelSodium-dependent noradrenaline transportertarget
DB00264MetoprololBeta-1 adrenergic receptortarget
DB00264MetoprololCytochrome P450 2D6enzyme
DB00264MetoprololBeta-2 adrenergic receptortarget
DB00264MetoprololSolute carrier family 22 member 2transporter
DB00264MetoprololMultidrug resistance protein 1transporter
DB00264MetoprololCytochrome P450 2C19enzyme
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00270IsradipineCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00275OlmesartanType-1 angiotensin II receptortarget
DB00275OlmesartanCanalicular multispecific organic anion transporter 1transporter
DB00275OlmesartanSolute carrier organic anion transporter family member 1B3transporter
DB00275OlmesartanSolute carrier organic anion transporter family member 1B1transporter
DB00287TravoprostProstaglandin F2-alpha receptortarget
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00335AtenololBeta-1 adrenergic receptortarget
DB00335AtenololMultidrug resistance protein 1transporter
DB00335AtenololBeta-2 adrenergic receptortarget
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemMultidrug resistance protein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemCytochrome P450 2C9enzyme
DB00373TimololBeta-1 adrenergic receptortarget
DB00373TimololBeta-2 adrenergic receptortarget
DB00373TimololCytochrome P450 2D6enzyme
DB00373TimololMultidrug resistance protein 1transporter
DB00373TimololCytochrome P450 2C19enzyme
DB00373TimololLysozymetarget
DB00374TreprostinilP2Y purinoceptor 12target
DB00374TreprostinilPeroxisome proliferator-activated receptor deltatarget
DB00374TreprostinilProstacyclin receptortarget
DB00374TreprostinilCytochrome P450 2C9enzyme
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00381AmlodipineVoltage-gated calcium channel beta 1 subunit splice variant CavB1dtarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineCytochrome P450 3A7enzyme
DB00381AmlodipineCytochrome P450 1A2enzyme
DB00381AmlodipineMultidrug resistance protein 1transporter
DB00381AmlodipineCytochrome P450 2A6enzyme
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2C9enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00393NimodipineCytochrome P450 3A4enzyme
DB00393NimodipineMineralocorticoid receptortarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
DB00393NimodipineCytochrome P450 3A5enzyme
DB00393NimodipineAryl hydrocarbon receptortarget
DB00401NisoldipineCytochrome P450 3A4enzyme
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00401NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00401NisoldipineCytochrome P450 3A5enzyme
DB00401NisoldipineCytochrome P450 3A7enzyme
DB00401NisoldipineMultidrug resistance protein 1transporter
DB00401NisoldipineCytochrome P450 1A2enzyme
DB00436BendroflumethiazideSolute carrier family 12 member 3target
DB00436BendroflumethiazideCarbonic anhydrase 1target
DB00436BendroflumethiazideCarbonic anhydrase 2target
DB00436BendroflumethiazideCarbonic anhydrase 4target
DB00436BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00436BendroflumethiazideThiopurine S-methyltransferaseenzyme
DB00484BrimonidineAlpha-2A adrenergic receptortarget
DB00484BrimonidineAlpha-2B adrenergic receptortarget
DB00484BrimonidineAlpha-2C adrenergic receptortarget
DB00484BrimonidineAldehyde oxidaseenzyme
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilAngiotensin-converting enzymetarget
DB00519TrandolaprilSolute carrier family 15 member 1transporter
DB00519TrandolaprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilLiver carboxylesterase 1enzyme
DB00521CarteololBeta-2 adrenergic receptortarget
DB00521CarteololBeta-1 adrenergic receptortarget
DB00521CarteololCytochrome P450 2D6enzyme
DB00524MetolazoneSolute carrier family 12 member 3target
DB00528LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
DB00528LercanidipineCytochrome P450 3A4enzyme
DB00528LercanidipineCytochrome P450 3A5enzyme
DB00528LercanidipineCytochrome P450 3A7enzyme
DB00528LercanidipineCytochrome P450 2D6enzyme
DB00542BenazeprilAngiotensin-converting enzymetarget
DB00542BenazeprilMethylenetetrahydrofolate reductaseenzyme
DB00542BenazeprilSolute carrier family 15 member 1transporter
DB00542BenazeprilSolute carrier family 15 member 2transporter
DB00571PropranololBeta-1 adrenergic receptortarget
DB00571PropranololBeta-2 adrenergic receptortarget
DB00571PropranololBeta-3 adrenergic receptortarget
DB00571Propranolol5-hydroxytryptamine receptor 1Atarget
DB00571Propranolol5-hydroxytryptamine receptor 1Btarget
DB00571PropranololCytochrome P450 1A2enzyme
DB00571PropranololCytochrome P450 2D6enzyme
DB00571PropranololAlpha-1-acid glycoprotein 1carrier
DB00571PropranololCytochrome P450 2C19enzyme
DB00571PropranololCytochrome P450 3A4enzyme
DB00571PropranololCytochrome P450 3A5enzyme
DB00571PropranololCytochrome P450 3A7enzyme
DB00571PropranololSolute carrier family 22 member 2transporter
DB00571PropranololMultidrug resistance protein 1transporter
DB00571PropranololCytochrome P450 1A1enzyme
DB00584EnalaprilAngiotensin-converting enzymetarget
DB00584EnalaprilCytochrome P450 3A4enzyme
DB00584EnalaprilMultidrug resistance protein 1transporter
DB00584EnalaprilSolute carrier family 15 member 1transporter
DB00584EnalaprilSolute carrier family 22 member 6transporter
DB00584EnalaprilSolute carrier family 22 member 8transporter
DB00584EnalaprilSolute carrier family 22 member 7transporter
DB00584EnalaprilSolute carrier organic anion transporter family member 1A2transporter
DB00598LabetalolAlpha-1 adrenergic receptorstarget
DB00598LabetalolBeta-1 adrenergic receptortarget
DB00598LabetalolBeta-2 adrenergic receptortarget
DB00598LabetalolCytochrome P450 2D6enzyme
DB00606CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
DB00606CyclothiazideCarbonic anhydrase 1target
DB00606CyclothiazideCarbonic anhydrase 2target
DB00606CyclothiazideCarbonic anhydrase 4target
DB00606CyclothiazideSolute carrier family 22 member 6transporter
DB00606CyclothiazideSecreted frizzled-related protein 4target
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 2D6enzyme
DB00612BisoprololCytochrome P450 3A4enzyme
DB00616CandoxatrilNeprilysintarget
DB00616CandoxatrilAngiotensin-converting enzymetarget
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C9enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineMultidrug resistance protein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00629GuanabenzAlpha-2A adrenergic receptortarget
DB00629GuanabenzCytochrome P450 1A2enzyme
DB00629GuanabenzAlpha-2B adrenergic receptortarget
DB00654LatanoprostProstaglandin F2-alpha receptortarget
DB00654LatanoprostSolute carrier organic anion transporter family member 2B1transporter
DB00654LatanoprostSolute carrier family 22 member 1transporter
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanCytochrome P450 2C8enzyme
DB00678LosartanMultidrug resistance protein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 1A2enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanCytochrome P450 3A5enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00691MoexiprilAngiotensin-converting enzymetarget
DB00691MoexiprilSolute carrier family 15 member 1transporter
DB00691MoexiprilSolute carrier family 15 member 2transporter
DB00691MoexiprilAngiotensin-converting enzyme 2target
DB00692PhentolamineAlpha-2A adrenergic receptortarget
DB00692PhentolamineAlpha-1A adrenergic receptortarget
DB00692PhentolamineAlpha-1B adrenergic receptortarget
DB00692PhentolamineAlpha-1D adrenergic receptortarget
DB00722LisinoprilAngiotensin-converting enzymetarget
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00785CryptenamineMuscarinic acetylcholine receptor M2target
DB00785CryptenamineMuscarinic acetylcholine receptor M1target
DB00785CryptenamineMuscarinic acetylcholine receptor M4target
DB00785CryptenamineMuscarinic acetylcholine receptor M5target
DB00785CryptenamineMuscarinic acetylcholine receptor M3target
DB00790PerindoprilAngiotensin-converting enzymetarget
DB00790PerindoprilMultidrug resistance protein 1transporter
DB00790PerindoprilSolute carrier family 15 member 1transporter
DB00790PerindoprilSolute carrier family 15 member 2transporter
DB00790PerindoprilCholinesteraseenzyme
DB00790PerindoprilSecreted frizzled-related protein 4target
DB00796CandesartanType-1 angiotensin II receptortarget
DB00796CandesartanCytochrome P450 2C8enzyme
DB00796CandesartanCytochrome P450 2C9enzyme
DB00796CandesartanMultidrug resistance protein 1transporter
DB00796CandesartanUDP-glucuronosyltransferase 1-3enzyme
DB00796CandesartanProstaglandin G/H synthase 1enzyme
DB00797TolazolineAlpha-1A adrenergic receptortarget
DB00797TolazolineAlpha-2A adrenergic receptortarget
DB00797TolazolineHistamine H1 receptortarget
DB00797TolazolineHistamine H2 receptortarget
DB00797TolazolineAlpha-2C adrenergic receptortarget
DB00797TolazolineAlpha-2B adrenergic receptortarget
DB00800FenoldopamD(1B) dopamine receptortarget
DB00800FenoldopamD(1A) dopamine receptortarget
DB00800FenoldopamAlpha-2B adrenergic receptortarget
DB00800FenoldopamAlpha-2C adrenergic receptortarget
DB00800FenoldopamAlpha-2A adrenergic receptortarget
DB00800FenoldopamAlpha-1B adrenergic receptortarget
DB00800FenoldopamAlpha-1D adrenergic receptortarget
DB00800FenoldopamAlpha-1A adrenergic receptortarget
DB00808IndapamidePotassium voltage-gated channel subfamily KQT member 1target
DB00808IndapamidePotassium voltage-gated channel subfamily E member 1target
DB00808IndapamideCytochrome P450 3A4enzyme
DB00866AlprenololBeta-1 adrenergic receptortarget
DB00866AlprenololBeta-2 adrenergic receptortarget
DB00866Alprenolol5-hydroxytryptamine receptor 1Atarget
DB00866AlprenololCytochrome P450 2D6enzyme
DB00866AlprenololBeta-3 adrenergic receptortarget
DB00869DorzolamideCarbonic anhydrase 2target
DB00869DorzolamideCarbonic anhydrase 1target
DB00869DorzolamideCarbonic anhydrase 4target
DB00869DorzolamideCytochrome P450 2C9enzyme
DB00869DorzolamideCytochrome P450 3A4enzyme
DB00869DorzolamideCarbonic anhydrase 3target
DB00876EprosartanType-1 angiotensin II receptortarget
DB00876EprosartanCanalicular multispecific organic anion transporter 1transporter
DB00876EprosartanCytochrome P450 2C9enzyme
DB00880ChlorothiazideSolute carrier family 12 member 3target
DB00880ChlorothiazideCarbonic anhydrase 1target
DB00880ChlorothiazideCarbonic anhydrase 2target
DB00880ChlorothiazideCarbonic anhydrase 4target
DB00880ChlorothiazideSolute carrier family 22 member 6transporter
DB00881QuinaprilAngiotensin-converting enzymetarget
DB00881QuinaprilSolute carrier family 15 member 1transporter
DB00881QuinaprilSolute carrier family 15 member 2transporter
DB00886OmapatrilatNeprilysintarget
DB00886OmapatrilatAngiotensin-converting enzymetarget
DB00905BimatoprostProstaglandin F2-alpha receptortarget
DB00905BimatoprostProstaglandin E2 receptor EP1 subtypetarget
DB00905BimatoprostProstaglandin E2 receptor EP3 subtypetarget
DB00905BimatoprostAldo-keto reductase family 1 member C3target
DB00925PhenoxybenzamineAlpha-1A adrenergic receptortarget
DB00925PhenoxybenzamineCalmodulintarget
DB00925PhenoxybenzamineSolute carrier family 22 member 2transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 1transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 3transporter
DB00925PhenoxybenzamineCytochrome P450 3A4enzyme
DB00925PhenoxybenzamineAlpha-2A adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2C adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2B adrenergic receptortarget
DB00925PhenoxybenzamineBeta-2 adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1B adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1D adrenergic receptortarget
DB00960PindololBeta-1 adrenergic receptortarget
DB00960PindololBeta-2 adrenergic receptortarget
DB00960Pindolol5-hydroxytryptamine receptor 1Atarget
DB00960Pindolol5-hydroxytryptamine receptor 1Btarget
DB00960PindololCytochrome P450 2D6enzyme
DB00960PindololBeta-3 adrenergic receptortarget
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanMultidrug resistance protein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00968MethyldopaAlpha-2A adrenergic receptortarget
DB00968MethyldopaCatechol O-methyltransferaseenzyme
DB00968MethyldopaSolute carrier family 15 member 1transporter
DB00968MethyldopaAromatic-L-amino-acid decarboxylasetarget
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideCarbonic anhydrase 1target
DB00999HydrochlorothiazideCarbonic anhydrase 2target
DB00999HydrochlorothiazideCarbonic anhydrase 4target
DB00999HydrochlorothiazideCarbonic anhydrase 9target
DB00999HydrochlorothiazideCarbonic anhydrase 12target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB01021TrichlormethiazideSolute carrier family 12 member 1target
DB01021TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB01021TrichlormethiazideCarbonic anhydrase 4target
DB01021TrichlormethiazideCarbonic anhydrase 2target
DB01021TrichlormethiazideCarbonic anhydrase 1target
DB01021TrichlormethiazideThiopurine S-methyltransferaseenzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineMultidrug resistance protein 1transporter
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01029IrbesartanType-1 angiotensin II receptortarget
DB01029IrbesartanTranscription factor AP-1target
DB01029IrbesartanCytochrome P450 2C9enzyme
DB01029IrbesartanCytochrome P450 2C8enzyme
DB01029IrbesartanUDP-glucuronosyltransferase 1-3enzyme
DB01029IrbesartanProstaglandin G/H synthase 1enzyme
DB01029IrbesartanCytochrome P450 1A2enzyme
DB01029IrbesartanCytochrome P450 2D6enzyme
DB01029IrbesartanCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineMultidrug resistance protein 1transporter
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolMultidrug resistance protein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolProstaglandin G/H synthase 1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01158BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololSolute carrier family 22 member 1transporter
DB01193AcebutololMultidrug resistance protein 1transporter
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilCytochrome P450 2D6enzyme
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilMultidrug resistance protein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB01203NadololBeta-1 adrenergic receptortarget
DB01203NadololBeta-2 adrenergic receptortarget
DB01203NadololMultidrug resistance protein 1transporter
DB01214MetipranololBeta-1 adrenergic receptortarget
DB01214MetipranololBeta-2 adrenergic receptortarget
DB01240EpoprostenolP2Y purinoceptor 12target
DB01240EpoprostenolProstacyclin receptortarget
DB01240EpoprostenolProstacyclin synthasetarget
DB01240EpoprostenolCytochrome P450 2C9enzyme
DB01244BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1target
DB01244BepridilPotassium voltage-gated channel subfamily KQT member 1target
DB01244BepridilTroponin C, slow skeletal and cardiac musclestarget
DB01244BepridilCalmodulintarget
DB01244BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01244BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01244BepridilMultidrug resistance protein 1transporter
DB01244BepridilCytochrome P450 2D6enzyme
DB01244BepridilPotassium voltage-gated channel subfamily H member 2target
DB01324PolythiazideSolute carrier family 12 member 3target
DB01340CilazaprilAngiotensin-converting enzymetarget
DB01340CilazaprilMultidrug resistance protein 1transporter
DB01340CilazaprilSolute carrier family 15 member 1transporter
DB01340CilazaprilSolute carrier family 15 member 2transporter
DB01347SaprisartanType-1 angiotensin II receptortarget
DB01348SpiraprilAngiotensin-converting enzymetarget
DB01348SpiraprilSolute carrier family 15 member 1transporter
DB01348SpiraprilSolute carrier family 15 member 2transporter
DB01359PenbutololAlpha-1-acid glycoprotein 1carrier
DB01359PenbutololBeta-1 adrenergic receptortarget
DB01359PenbutololBeta-2 adrenergic receptortarget
DB01359Penbutolol5-hydroxytryptamine receptor 1Atarget
DB01359Penbutolol5-hydroxytryptamine receptor 1Btarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
DB01388MibefradilCytochrome P450 3A4enzyme
DB01388MibefradilCytochrome P450 1A2enzyme
DB01388MibefradilCytochrome P450 2D6enzyme
DB01388MibefradilCytochrome P450 3A5enzyme
DB01388MibefradilCytochrome P450 3A7enzyme
DB01388MibefradilMultidrug resistance protein 1transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
DB01388MibefradilCytochrome P450 11B1, mitochondrialenzyme
DB01388MibefradilCytochrome P450 11B2, mitochondrialenzyme
DB01388MibefradilCytochrome P450 1A1enzyme
DB01580OxprenololBeta-1 adrenergic receptortarget
DB01580OxprenololBeta-2 adrenergic receptortarget
DB01580OxprenololSolute carrier family 22 member 2transporter
DB01580OxprenololCytochrome P450 2D6enzyme
DB01580OxprenololBeta-3 adrenergic receptortarget
DB02638TerlipressinVasopressin V1a receptortarget
DB02638TerlipressinVasopressin V2 receptortarget
DB02638TerlipressinVasopressin V1b receptortarget
DB04831TicrynafenCytochrome P450 2C9enzyme
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololCytochrome P450 3A4enzyme
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04861NebivololBeta-1 adrenergic receptortarget
DB04861NebivololCytochrome P450 2D6enzyme
DB04861NebivololBeta-2 adrenergic receptortarget
DB04948LofexidineAlpha-2A adrenergic receptortarget
DB06694XylometazolineAlpha-2A adrenergic receptortarget
DB06694XylometazolineAlpha-1A adrenergic receptortarget
DB06694XylometazolineAlpha-1B adrenergic receptortarget
DB06694XylometazolineAlpha-1D adrenergic receptortarget
DB06694XylometazolineAlpha-2B adrenergic receptortarget
DB06694XylometazolineAlpha-2C adrenergic receptortarget
DB06712NilvadipineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 1A2enzyme
DB06712NilvadipineCytochrome P450 2A6enzyme
DB06712NilvadipineCytochrome P450 2C19enzyme
DB06712NilvadipineCytochrome P450 2C8enzyme
DB06712NilvadipineCytochrome P450 2C9enzyme
DB06712NilvadipineCytochrome P450 2E1enzyme
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB07767Ferulic acidEndo-1,4-beta-xylanase Ytarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ztarget
DB07767Ferulic acidEst1etarget
DB07767Ferulic acidO-methyltransferasetarget
DB08808BupranololBeta-1 adrenergic receptortarget
DB08808BupranololBeta-2 adrenergic receptortarget
DB08808BupranololBeta-3 adrenergic receptortarget
DB08836TemocaprilSolute carrier family 15 member 1transporter
DB08836TemocaprilSolute carrier organic anion transporter family member 1A2transporter
DB08836TemocaprilAngiotensin-converting enzymetarget
DB09026AliskirenRenintarget
DB09026AliskirenCytochrome P450 3A4enzyme
DB09070TiboloneEstrogen receptor alphatarget
DB09220NicorandilATP-binding cassette sub-family C member 9target
DB09238ManidipineVoltage dependent L type calcium channeltarget
DB09238ManidipineVoltage-dependent T-type calcium channeltarget
DB09238ManidipineCytochrome P450 2C9enzyme
DB09238ManidipineCytochrome P450 2D6enzyme
DB09238ManidipineCytochrome P450 1A1enzyme
DB09238ManidipineCytochrome P450 1A2enzyme
DB09238ManidipineCytochrome P450 2B6enzyme
DB09238ManidipineCytochrome P450 2C19enzyme
DB09238ManidipineCytochrome P450 3A4enzyme
DB09239NiguldipineAlpha-1A adrenergic receptortarget
DB09477EnalaprilatAngiotensin-converting enzymetarget
DB09477EnalaprilatB1 bradykinin receptortarget