Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
DrugDrug NameDrug Description
DB00206ReserpineFoe the treatment of hypertension
DB00217BethanidineFor the treatment of hypertension.
DB00325NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
DB00350MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
DB00457PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
DB00559BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
DB00575ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
DB00590DoxazosinAn alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
DB00657MecamylamineA nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension.
DB01018GuanfacineAn alpha-2A adrenergic receptor agonist used to treat ADHD.
DB01116TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
DB01275HydralazineAn antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia .
DB01626PargylineFor the treatment of moderate to severe hypertension.
DB04840DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
DB06762PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
DB08950IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
DB09206TrimazosinTrimazosin is a sympatholytic alpha blocker.
DB09242MoxonidineFor the treatment of mild to moderate essential or primary hypertension . Effective as most first-line antihypertensives when used as monotherapy .
DB11738RilmenidineRilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.
DB12465KetanserinKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
DB12945DihydralazineDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
DB12661UrapidilUrapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
DB13435EndralazineNot Annotated
DB13452CadralazineNot Annotated
DB13575BietaserpineNot Annotated
DB00177ValsartanAn angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
DB00178RamiprilAn ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
DB00195BetaxololA cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
DB00212RemikirenFor the treatment of hypertension and heart failure
DB00214TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
DB00226GuanadrelUsed to treat and control hypertension.
DB00264MetoprololA beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
DB00270IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
DB00275OlmesartanAn angiotensin receptor blocker (ARB) used in the treatment of hypertension.
DB00287TravoprostA prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
DB00310ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DB00335AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
DB00343DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DB00374TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
DB00381AmlodipineA calcium channel blocker used to treat hypertension and angina.
DB00393NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
DB00401NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
DB00436BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
DB00492FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
DB00519TrandolaprilA prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction.
DB00524MetolazoneA thiazide-like diuretic used to treat hypertension.
DB00528LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
DB00542BenazeprilAn ACE inhibitor prodrug used to treat hypertension.
DB00584EnalaprilA prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
DB00598LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
DB00606CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
DB00612BisoprololA beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
DB00616CandoxatrilCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB00629GuanabenzAn alpha-2 adrenergic agonist used to treat hypertension.
DB00654LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
DB00678LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
DB00691MoexiprilAn angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
DB00692PhentolamineAn alpha adrenergic antagonist used to reverse soft tissue anesthesia.
DB00722LisinoprilAn ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
DB00774HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
DB00785CryptenamineFor the treatment of hypertension.
DB00790PerindoprilAn ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
DB00796Candesartan cilexetilAn angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
DB00797TolazolineA vasodilator used to treat pulmonary artery anomalies.
DB00800FenoldopamA dopamine D1 receptor agonist used for the short term management of hypertension.
DB00808IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
DB00869DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
DB00876EprosartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
DB00880ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
DB00881QuinaprilAn ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
DB00886OmapatrilatFor the treatment of hypertension.
DB00905BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
DB00925PhenoxybenzamineAn alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating.
DB00966TelmisartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
DB00968MethyldopaAn alpha-2 adrenergic agonist used to treat hypertension.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB01021TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
DB01023FelodipineA calcium channel blocker used to treat hypertension.
DB01029IrbesartanAn angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01090PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
DB01119DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
DB01136CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
DB01158BretyliumA norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias.
DB01170GuanethidineAn antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension.
DB01193AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
DB01197CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
DB01214MetipranololA beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
DB01240EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
DB01244BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
DB01324PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
DB01340CilazaprilAn ACE inhibitor used for the management of hypertension and heart failure.
DB01347SaprisartanSaprisartan is used in the treatment of hypertension and heart failure.
DB01348SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
DB01388MibefradilFor the treatment of angina and high blood pressure.
DB04831Tienilic acidFor the treatment of hypertension.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB04861NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
DB04948LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
DB06445DiethylnorspermineInvestigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
DB06712NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
DB06826UnoprostoneA prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
DB07767Ferulic acidNot Available
DB08836TemocaprilTemocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
DB08952IndenololIndenolol is a drug of the beta-adrenergic blocker class.
DB08960HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
DB09026AliskirenA direct renin inhibitor used to manage hypertension.
DB09220NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
DB09235EfonidipineFor the treatment of hypertension.
DB09236LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
DB09238ManidipineFor the treatment of hypertension.
DB09239NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
DB09477EnalaprilatAn antihypertensive agent used for the management of hypertension when oral therapy is not practical.
DB11362SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
DB11770TalinololTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
DB11783ImidaprilImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
DB12054BQ-123BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
DB12092NaftopidilNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
DB12093TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
DB13166ZofenoprilZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
DB13312DelaprilNot Annotated
DB13374VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
DB13400LinsidomineNot Annotated
DB13532CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
DB13757EpanololEpanolol is an beta blocker.
DB13801MuzolimineNot Annotated
DB13803XipamideNot Annotated
DB13919CandesartanCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of Candesartan cilexetil.
DB00765MetyrosineA tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma.
DB01089DeserpidineAn alkaloid that has been used to manage hypertension.
DB01180RescinnamineFor the treatment of hypertension.
DB06268SitaxentanInvestigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.
DB06403AmbrisentanA selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
DB08931RiociguatA stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.
DB08932MacitentanAn endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
DB13211GuanoxanGuanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. Guanoxan was approved in the UK but was withdrawn from the market due...
DB13410GuanoxabenzNot Annotated
DB13429TolonidineNot Annotated
DB13604GuanazodineNot Annotated
DB13631MethoserpidineNot Annotated
DB13779GuanoclorNot Annotated
DB00187EsmololA cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
DB01297PractololUsed in the emergency treatment of cardiac arrhythmias.
DB13443EsatenololEsatenolol is a beta blocker.
DB01295BevantololFor the treatment of angina pectoris and hypertension.
DB12766CicletanineCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
DB14068DexniguldipineNot Annotated
DB14094TocopherylquinoneNot Annotated
DB14125BenazeprilatNot Annotated
DB01162TerazosinAn alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension.
DB14207FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
DB14208RamiprilatThe active metabolite of the prodrug Ramipril.
DB14213PerindoprilatThe active metabolite of the prodrug Perindopril.
DB14217QuinaprilatThe active metabolite of the prodrug quinapril.
DB00373TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
DB00521CarteololA beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
DB00571PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
DB00866AlprenololFor the treatment of hypertension, angina, and arrhythmia
DB00960PindololA beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
DB01203NadololA non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension.
DB01359PenbutololA beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents.
DB01580OxprenololA non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
DB08808BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
DB13508CloranololNot Annotated
DB03322DexpropranololNot Available
DB09363Rauwolfia serpentina rootRauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics...
DB00727NitroglycerinA nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively.
DB00820TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DB12212LandiololLandiolol has been used in trials studying the treatment of Pharmacokinetics/Dynamics Study.
DB00700EplerenoneAn aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
DB11720Angiotensin 1-7TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
DB00695FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DB15565CilazaprilatNot Annotated
DrugDrug NameTargetType
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineP-glycoprotein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00206ReserpineSolute carrier organic anion transporter family member 1B1transporter
DB00206ReserpineSolute carrier organic anion transporter family member 2B1transporter
DB00217BethanidineAlpha-2 adrenergic receptorstarget
DB00217BethanidineATP-sensitive inward rectifier potassium channel 1target
DB00217BethanidineBeta adrenergic receptortarget
DB00325NitroprussideAtrial natriuretic peptide receptor 1target
DB00325NitroprussideCytochrome P450 1A1enzyme
DB00350MinoxidilATP-sensitive inward rectifier potassium channel 1target
DB00350MinoxidilProstaglandin G/H synthase 1target
DB00350MinoxidilRenintarget
DB00350MinoxidilUDP-glucuronosyltransferase 1-1enzyme
DB00457PrazosinAlpha-1A adrenergic receptortarget
DB00457PrazosinAlpha-1B adrenergic receptortarget
DB00457PrazosinAlpha-1D adrenergic receptortarget
DB00457PrazosinPotassium voltage-gated channel subfamily H member 2target
DB00457PrazosinAlpha-1-acid glycoprotein 1carrier
DB00457PrazosinSolute carrier family 22 member 1transporter
DB00457PrazosinSolute carrier family 22 member 3transporter
DB00457PrazosinP-glycoprotein 1transporter
DB00457PrazosinATP-binding cassette sub-family G member 2transporter
DB00457PrazosinAlpha-2A adrenergic receptortarget
DB00457PrazosinAlpha-2B adrenergic receptortarget
DB00457PrazosinAlpha-1 adrenergic receptorstarget
DB00559BosentanEndothelin B receptortarget
DB00559BosentanEndothelin-1 receptortarget
DB00559BosentanCytochrome P450 3A4enzyme
DB00559BosentanCytochrome P450 2C9enzyme
DB00559BosentanBile salt export pumptransporter
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineP-glycoprotein 1transporter
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00575ClonidineSerum albumincarrier
DB00590DoxazosinAlpha-1A adrenergic receptortarget
DB00590DoxazosinAlpha-1D adrenergic receptortarget
DB00590DoxazosinHERG human cardiac K+ channeltarget
DB00590DoxazosinP-glycoprotein 1transporter
DB00590DoxazosinCytochrome P450 2C19enzyme
DB00590DoxazosinCytochrome P450 2D6enzyme
DB00590DoxazosinSolute carrier family 22 member 1transporter
DB00590DoxazosinCytochrome P450 3A4enzyme
DB00590DoxazosinAlpha-1B adrenergic receptortarget
DB00590DoxazosinCytochrome P450 2C9enzyme
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
DB00657MecamylamineNeuronal acetylcholine receptor subunit beta-2target
DB01018GuanfacineAlpha-2A adrenergic receptortarget
DB01018GuanfacineCytochrome P450 2C19enzyme
DB01018GuanfacineCytochrome P450 3A4enzyme
DB01018GuanfacineAlpha-2B adrenergic receptortarget
DB01116TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
DB01116TrimethaphanCholinesteraseenzyme
DB01275HydralazineMembrane primary amine oxidasetarget
DB01275HydralazineProlyl 4-hydroxylase subunit alpha-1target
DB01275HydralazineCytochrome P450 3A4enzyme
DB01275HydralazineSerum albumincarrier
DB01275HydralazineHypoxia-inducible factor 1-alphatarget
DB01626PargylineAmine oxidase [flavin-containing] Btarget
DB01626PargylineAmine oxidase [flavin-containing] Atarget
DB04840DebrisoquineSodium-dependent noradrenaline transportertarget
DB04840DebrisoquineCytochrome P450 2D6enzyme
DB04840DebrisoquineP-glycoprotein 1transporter
DB04840DebrisoquineCytochrome P450 1A1enzyme
DB06762PinacidilCytochrome P450 3A4enzyme
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB09242MoxonidineNischarintarget
DB09242MoxonidineAlpha-2A adrenergic receptortarget
DB11738RilmenidineAlpha-2A adrenergic receptortarget
DB12465Ketanserin5-hydroxytryptamine receptor 2Atarget
DB12945DihydralazineCytochrome P450 1A2enzyme
DB00177ValsartanType-1 angiotensin II receptortarget
DB00177ValsartanCytochrome P450 2C9enzyme
DB00177ValsartanSolute carrier organic anion transporter family member 1B3transporter
DB00177ValsartanSolute carrier organic anion transporter family member 1B1transporter
DB00177ValsartanCanalicular multispecific organic anion transporter 1transporter
DB00178RamiprilAngiotensin-converting enzymetarget
DB00178RamiprilSolute carrier family 15 member 1transporter
DB00178RamiprilSolute carrier family 15 member 2transporter
DB00178RamiprilCholinesteraseenzyme
DB00178RamiprilB1 bradykinin receptortarget
DB00195BetaxololBeta-1 adrenergic receptortarget
DB00195BetaxololBeta-2 adrenergic receptortarget
DB00195BetaxololCytochrome P450 1A2enzyme
DB00195BetaxololCytochrome P450 2D6enzyme
DB00212RemikirenRenintarget
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier organic anion transporter family member 1B1transporter
DB00214TorasemideSolute carrier family 12 member 2target
DB00214TorasemideSerum albumincarrier
DB00226GuanadrelSodium-dependent noradrenaline transportertarget
DB00264MetoprololBeta-1 adrenergic receptortarget
DB00264MetoprololCytochrome P450 2D6enzyme
DB00264MetoprololBeta-2 adrenergic receptortarget
DB00264MetoprololSolute carrier family 22 member 2transporter
DB00264MetoprololP-glycoprotein 1transporter
DB00264MetoprololSerum albumincarrier
DB00264MetoprololCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00270IsradipineCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00270IsradipineBile salt export pumptransporter
DB00275OlmesartanType-1 angiotensin II receptortarget
DB00275OlmesartanCanalicular multispecific organic anion transporter 1transporter
DB00275OlmesartanSolute carrier organic anion transporter family member 1B3transporter
DB00275OlmesartanSolute carrier organic anion transporter family member 1B1transporter
DB00275OlmesartanBile salt export pumptransporter
DB00275OlmesartanSerum albumincarrier
DB00287TravoprostProstaglandin F2-alpha receptortarget
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00335AtenololBeta-1 adrenergic receptortarget
DB00335AtenololBeta-2 adrenergic receptortarget
DB00335AtenololCytochrome P450 2D6enzyme
DB00335AtenololBile salt export pumptransporter
DB00335AtenololSerum albumincarrier
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemP-glycoprotein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemSerum albumincarrier
DB00343DiltiazemAlpha-1-acid glycoprotein 1carrier
DB00343DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00374TreprostinilP2Y purinoceptor 12target
DB00374TreprostinilPeroxisome proliferator-activated receptor deltatarget
DB00374TreprostinilProstacyclin receptortarget
DB00374TreprostinilCytochrome P450 2C9enzyme
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineP-glycoprotein 1transporter
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00381AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00381AmlodipineVoltage-dependent N-type calcium channeltarget
DB00393NimodipineCytochrome P450 3A4enzyme
DB00393NimodipineMineralocorticoid receptortarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
DB00393NimodipineAryl hydrocarbon receptortarget
DB00401NisoldipineCytochrome P450 3A4enzyme
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00401NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00401NisoldipineCytochrome P450 3A5enzyme
DB00401NisoldipineCytochrome P450 3A7enzyme
DB00401NisoldipineP-glycoprotein 1transporter
DB00436BendroflumethiazideSolute carrier family 12 member 3target
DB00436BendroflumethiazideCarbonic anhydrase 1target
DB00436BendroflumethiazideCarbonic anhydrase 2target
DB00436BendroflumethiazideCarbonic anhydrase 4target
DB00436BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00436BendroflumethiazideThiopurine S-methyltransferaseenzyme
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilAngiotensin-converting enzymetarget
DB00519TrandolaprilSolute carrier family 15 member 1transporter
DB00519TrandolaprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilLiver carboxylesterase 1enzyme
DB00524MetolazoneSolute carrier family 12 member 3target
DB00528LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
DB00528LercanidipineCytochrome P450 3A4enzyme
DB00528LercanidipineCytochrome P450 3A5enzyme
DB00528LercanidipineCytochrome P450 3A7enzyme
DB00528LercanidipineCytochrome P450 2D6enzyme
DB00542BenazeprilAngiotensin-converting enzymetarget
DB00542BenazeprilMethylenetetrahydrofolate reductaseenzyme
DB00542BenazeprilSolute carrier family 15 member 1transporter
DB00542BenazeprilSolute carrier family 15 member 2transporter
DB00584EnalaprilAngiotensin-converting enzymetarget
DB00584EnalaprilP-glycoprotein 1transporter
DB00584EnalaprilSolute carrier family 15 member 1transporter
DB00584EnalaprilSolute carrier family 22 member 6transporter
DB00584EnalaprilSolute carrier family 22 member 8transporter
DB00584EnalaprilSolute carrier family 22 member 7transporter
DB00584EnalaprilSolute carrier organic anion transporter family member 1A2transporter
DB00584EnalaprilSerum albumincarrier
DB00598LabetalolAlpha-1 adrenergic receptorstarget
DB00598LabetalolBeta-1 adrenergic receptortarget
DB00598LabetalolBeta-2 adrenergic receptortarget
DB00598LabetalolCytochrome P450 2D6enzyme
DB00598LabetalolCytochrome P450 2C19enzyme
DB00598LabetalolSerum albumincarrier
DB00598Labetalolalpha1-acid glycoproteincarrier
DB00598LabetalolATP-binding cassette sub-family B member 5transporter
DB00598LabetalolUDP-glucuronosyltransferase 1-1enzyme
DB00598LabetalolUDP-glucuronosyltransferase 2B7enzyme
DB00598LabetalolUDP-glucuronosyltransferase 1-9enzyme
DB00606CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
DB00606CyclothiazideCarbonic anhydrase 1target
DB00606CyclothiazideCarbonic anhydrase 2target
DB00606CyclothiazideCarbonic anhydrase 4target
DB00606CyclothiazideSolute carrier family 22 member 6transporter
DB00606CyclothiazideSecreted frizzled-related protein 4target
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 3A4enzyme
DB00612BisoprololP-glycoprotein 1transporter
DB00616CandoxatrilNeprilysintarget
DB00616CandoxatrilAngiotensin-converting enzymetarget
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB00629GuanabenzAlpha-2A adrenergic receptortarget
DB00629GuanabenzCytochrome P450 1A2enzyme
DB00629GuanabenzAlpha-2B adrenergic receptortarget
DB00654LatanoprostProstaglandin F2-alpha receptortarget
DB00654LatanoprostSolute carrier organic anion transporter family member 2A1transporter
DB00654LatanoprostSolute carrier family 22 member 6transporter
DB00654LatanoprostSolute carrier family 22 member 8transporter
DB00654LatanoprostCorneal esterasesenzyme
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanP-glycoprotein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00678LosartanBile salt export pumptransporter
DB00678LosartanCytochrome P450 2C8enzyme
DB00691MoexiprilAngiotensin-converting enzymetarget
DB00691MoexiprilSolute carrier family 15 member 1transporter
DB00691MoexiprilSolute carrier family 15 member 2transporter
DB00691MoexiprilAngiotensin-converting enzyme 2target
DB00692PhentolamineAlpha-2A adrenergic receptortarget
DB00692PhentolamineAlpha-1A adrenergic receptortarget
DB00692PhentolamineAlpha-1B adrenergic receptortarget
DB00692PhentolamineAlpha-1D adrenergic receptortarget
DB00722LisinoprilAngiotensin-converting enzymetarget
DB00722LisinoprilSolute carrier family 15 member 1transporter
DB00722LisinoprilSolute carrier family 15 member 2transporter
DB00722LisinoprilRenintarget
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00785CryptenamineMuscarinic acetylcholine receptor M2target
DB00785CryptenamineMuscarinic acetylcholine receptor M1target
DB00785CryptenamineMuscarinic acetylcholine receptor M4target
DB00785CryptenamineMuscarinic acetylcholine receptor M5target
DB00785CryptenamineMuscarinic acetylcholine receptor M3target
DB00790PerindoprilAngiotensin-converting enzymetarget
DB00790PerindoprilSolute carrier family 15 member 1transporter
DB00790PerindoprilSolute carrier family 15 member 2transporter
DB00790PerindoprilCholinesteraseenzyme
DB00790PerindoprilSecreted frizzled-related protein 4target
DB00796Candesartan cilexetilType-1 angiotensin II receptortarget
DB00796Candesartan cilexetilCytochrome P450 2C8enzyme
DB00796Candesartan cilexetilCytochrome P450 2C9enzyme
DB00796Candesartan cilexetilP-glycoprotein 1transporter
DB00796Candesartan cilexetilUDP-glucuronosyltransferase 1-3enzyme
DB00796Candesartan cilexetilProstaglandin G/H synthase 1enzyme
DB00797TolazolineAlpha-1A adrenergic receptortarget
DB00797TolazolineAlpha-2A adrenergic receptortarget
DB00797TolazolineHistamine H1 receptortarget
DB00797TolazolineHistamine H2 receptortarget
DB00797TolazolineAlpha-2C adrenergic receptortarget
DB00797TolazolineAlpha-2B adrenergic receptortarget
DB00800FenoldopamDopamine D5 receptortarget
DB00800FenoldopamDopamine D1 receptortarget
DB00800FenoldopamAlpha-2B adrenergic receptortarget
DB00800FenoldopamAlpha-2C adrenergic receptortarget
DB00800FenoldopamAlpha-2A adrenergic receptortarget
DB00800FenoldopamAlpha-1B adrenergic receptortarget
DB00800FenoldopamAlpha-1D adrenergic receptortarget
DB00800FenoldopamAlpha-1A adrenergic receptortarget
DB00808IndapamideCytochrome P450 3A4enzyme
DB00808IndapamideSolute carrier family 12 member 3target
DB00869DorzolamideCarbonic anhydrase 2target
DB00869DorzolamideCarbonic anhydrase 1target
DB00869DorzolamideCarbonic anhydrase 4target
DB00869DorzolamideCytochrome P450 2C9enzyme
DB00869DorzolamideCarbonic anhydrase 3target
DB00876EprosartanType-1 angiotensin II receptortarget
DB00876EprosartanCanalicular multispecific organic anion transporter 1transporter
DB00880ChlorothiazideSolute carrier family 12 member 3target
DB00880ChlorothiazideCarbonic anhydrase 1target
DB00880ChlorothiazideCarbonic anhydrase 2target
DB00880ChlorothiazideSolute carrier family 22 member 6transporter
DB00881QuinaprilAngiotensin-converting enzymetarget
DB00881QuinaprilSolute carrier family 15 member 1transporter
DB00881QuinaprilSolute carrier family 15 member 2transporter
DB00881QuinaprilSolute carrier family 22 member 8transporter
DB00881QuinaprilLiver carboxylesterase 1enzyme
DB00881QuinaprilSerum albumincarrier
DB00886OmapatrilatNeprilysintarget
DB00886OmapatrilatAngiotensin-converting enzymetarget
DB00905BimatoprostProstaglandin F2-alpha receptortarget
DB00905BimatoprostProstaglandin E2 receptor EP1 subtypetarget
DB00905BimatoprostProstaglandin E2 receptor EP3 subtypetarget
DB00905BimatoprostCytochrome P450 3A4enzyme
DB00905BimatoprostCytochrome P450 3A5enzyme
DB00925PhenoxybenzamineAlpha-1A adrenergic receptortarget
DB00925PhenoxybenzamineCalmodulintarget
DB00925PhenoxybenzamineSolute carrier family 22 member 2transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 1transporter
DB00925PhenoxybenzamineSolute carrier family 22 member 3transporter
DB00925PhenoxybenzamineAlpha-2A adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2C adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-2B adrenergic receptortarget
DB00925PhenoxybenzamineBeta-2 adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1B adrenergic receptortarget
DB00925PhenoxybenzamineAlpha-1D adrenergic receptortarget
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanP-glycoprotein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00966TelmisartanBile salt export pumptransporter
DB00966TelmisartanUDP-glucuronosyltransferase 1-3enzyme
DB00968MethyldopaAlpha-2A adrenergic receptortarget
DB00968MethyldopaCatechol O-methyltransferaseenzyme
DB00968MethyldopaSolute carrier family 15 member 1transporter
DB00968MethyldopaAromatic-L-amino-acid decarboxylasetarget
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB01021TrichlormethiazideSolute carrier family 12 member 3target
DB01021TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB01021TrichlormethiazideCarbonic anhydrase 4target
DB01021TrichlormethiazideCarbonic anhydrase 2target
DB01021TrichlormethiazideCarbonic anhydrase 1target
DB01021TrichlormethiazideThiopurine S-methyltransferaseenzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineP-glycoprotein 1transporter
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01023FelodipineBile salt export pumptransporter
DB01029IrbesartanType-1 angiotensin II receptortarget
DB01029IrbesartanTranscription factor AP-1target
DB01029IrbesartanCytochrome P450 2C9enzyme
DB01029IrbesartanCytochrome P450 2C8enzyme
DB01029IrbesartanUDP-glucuronosyltransferase 1-3enzyme
DB01029IrbesartanProstaglandin G/H synthase 1enzyme
DB01029IrbesartanCytochrome P450 3A4enzyme
DB01029IrbesartanSerum albumincarrier
DB01029Irbesartanalpha1-acid glycoproteincarrier
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineP-glycoprotein 1transporter
DB01054NitrendipineBile salt export pumptransporter
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
DB01090PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
DB01090PentoliniumNeuronal acetylcholine receptor subunit beta-4target
DB01119DiazoxideSolute carrier family 12 member 3target
DB01119DiazoxideCarbonic anhydrase 1target
DB01119DiazoxideCarbonic anhydrase 2target
DB01119DiazoxideCalcium-activated potassium channel subunit alpha-1target
DB01119DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DB01119DiazoxideATP-sensitive inward rectifier potassium channel 11target
DB01119DiazoxideGlutamine synthetaseenzyme
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolP-glycoprotein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01136CarvedilolUDP-glucuronosyltransferase 1-1enzyme
DB01136CarvedilolSerum albumincarrier
DB01136CarvedilolUDP-glucuronosyltransferase 2B4enzyme
DB01136CarvedilolUDP-glucuronosyltransferase 2B7enzyme
DB01136CarvedilolInward rectifier potassium channel 2target
DB01158BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
DB01170GuanethidineSodium-dependent noradrenaline transportertarget
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololP-glycoprotein 1transporter
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilP-glycoprotein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB01214MetipranololBeta-1 adrenergic receptortarget
DB01214MetipranololBeta-2 adrenergic receptortarget
DB01214MetipranololCytochrome P450 2D6enzyme
DB01240EpoprostenolP2Y purinoceptor 12target
DB01240EpoprostenolProstacyclin receptortarget
DB01240EpoprostenolProstacyclin synthasetarget
DB01244BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1target
DB01244BepridilPotassium voltage-gated channel subfamily KQT member 1target
DB01244BepridilTroponin C, slow skeletal and cardiac musclestarget
DB01244BepridilCalmodulintarget
DB01244BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01244BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01244BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01244BepridilP-glycoprotein 1transporter
DB01244BepridilCytochrome P450 2D6enzyme
DB01244BepridilPotassium voltage-gated channel subfamily H member 2target
DB01244BepridilCytochrome P450 3A4enzyme
DB01324PolythiazideSolute carrier family 12 member 3target
DB01340CilazaprilAngiotensin-converting enzymetarget
DB01340CilazaprilP-glycoprotein 1transporter
DB01340CilazaprilSolute carrier family 15 member 1transporter
DB01340CilazaprilSolute carrier family 15 member 2transporter
DB01347SaprisartanType-1 angiotensin II receptortarget
DB01348SpiraprilAngiotensin-converting enzymetarget
DB01348SpiraprilSolute carrier family 15 member 1transporter
DB01348SpiraprilSolute carrier family 15 member 2transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
DB01388MibefradilCytochrome P450 3A4enzyme
DB01388MibefradilCytochrome P450 1A2enzyme
DB01388MibefradilCytochrome P450 2D6enzyme
DB01388MibefradilCytochrome P450 3A5enzyme
DB01388MibefradilCytochrome P450 3A7enzyme
DB01388MibefradilP-glycoprotein 1transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
DB01388MibefradilCytochrome P450 11B1, mitochondrialenzyme
DB01388MibefradilCytochrome P450 11B2, mitochondrialenzyme
DB04831Tienilic acidCytochrome P450 2C9enzyme
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget
DB04846CeliprololCytochrome P450 2D6enzyme
DB04861NebivololBeta-1 adrenergic receptortarget
DB04861NebivololCytochrome P450 2D6enzyme
DB04861NebivololBeta-2 adrenergic receptortarget
DB04861NebivololCytochrome P450 3A4enzyme
DB04861NebivololSerum albumincarrier
DB04861NebivololBeta-3 adrenergic receptortarget
DB04861NebivololCytochrome P450 2C19enzyme
DB04948LofexidineAlpha-2A adrenergic receptortarget
DB04948LofexidineAlpha-1A adrenergic receptortarget
DB04948Lofexidine5-hydroxytryptamine receptor 1Atarget
DB04948Lofexidine5-hydroxytryptamine receptor 7target
DB04948Lofexidine5-hydroxytryptamine receptor 2Ctarget
DB04948Lofexidine5-hydroxytryptamine receptor 1Dtarget
DB04948LofexidineCytochrome P450 2D6enzyme
DB04948LofexidineCytochrome P450 1A2enzyme
DB04948LofexidineCytochrome P450 2C19enzyme
DB04948LofexidineATP-binding cassette sub-family B member 5transporter
DB04948LofexidineMultidrug and toxin extrusion protein 1transporter
DB06712NilvadipineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 2A6enzyme
DB06712NilvadipineCytochrome P450 2C19enzyme
DB06712NilvadipineCytochrome P450 2C8enzyme
DB06712NilvadipineCytochrome P450 2E1enzyme
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB07767Ferulic acidEndo-1,4-beta-xylanase Ytarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ztarget
DB07767Ferulic acidEst1etarget
DB07767Ferulic acidO-methyltransferasetarget
DB08836TemocaprilSolute carrier family 15 member 1transporter
DB08836TemocaprilSolute carrier organic anion transporter family member 1A2transporter
DB08836TemocaprilAngiotensin-converting enzymetarget
DB08952IndenololCytochrome P450 2D6enzyme
DB08960HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target
DB09026AliskirenRenintarget
DB09026AliskirenCytochrome P450 3A4enzyme
DB09220NicorandilATP-binding cassette sub-family C member 9target
DB09235EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09235EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09235EfonidipineCytochrome P450 3A4enzyme
DB09236LacidipineCytochrome P450 3A4enzyme
DB09236LacidipineSerum albumincarrier
DB09236LacidipineAlpha-1-acid glycoprotein 1carrier
DB09236LacidipineVoltage-dependent L-type calcium channeltarget
DB09238ManidipineVoltage-dependent L-type calcium channeltarget
DB09238ManidipineVoltage-dependent T-type calcium channeltarget
DB09238ManidipineCytochrome P450 2C9enzyme
DB09238ManidipineCytochrome P450 2D6enzyme
DB09238ManidipineCytochrome P450 1A1enzyme
DB09238ManidipineCytochrome P450 2B6enzyme
DB09238ManidipineCytochrome P450 2C19enzyme
DB09238ManidipineCytochrome P450 3A4enzyme
DB09239NiguldipineAlpha-1A adrenergic receptortarget
DB09239NiguldipineCytochrome P450 3A4enzyme
DB09477EnalaprilatAngiotensin-converting enzymetarget
DB09477EnalaprilatB1 bradykinin receptortarget
DB11362SelexipagProstacyclin receptortarget
DB11362SelexipagLiver carboxylesterase 1enzyme
DB11362SelexipagCytochrome P450 2C8enzyme
DB11362SelexipagCytochrome P450 3A4enzyme
DB11362SelexipagSolute carrier organic anion transporter family member 1B1transporter
DB11362SelexipagSolute carrier organic anion transporter family member 1B3transporter
DB11362SelexipagP-glycoprotein 1transporter
DB11770TalinololCytochrome P450 2D6enzyme
DB12092NaftopidilCytochrome P450 3A4enzyme
DB12093TetrahydropalmatineDopamine D1 receptortarget
DB12093TetrahydropalmatineDopamine D2 receptortarget
DB12093TetrahydropalmatineCytochrome P450 3A4enzyme
DB13166ZofenoprilAngiotensin-converting enzymetarget
DB13757EpanololCytochrome P450 2D6enzyme
DB13919CandesartanType-1 angiotensin II receptortarget
DB13919CandesartanCytochrome P450 2C8enzyme
DB13919CandesartanCytochrome P450 2C9enzyme
DB13919CandesartanP-glycoprotein 1transporter
DB13919CandesartanUDP-glucuronosyltransferase 1-3enzyme
DB13919CandesartanProstaglandin G/H synthase 1enzyme
DB13919CandesartanSolute carrier organic anion transporter family member 1B1transporter
DB00765MetyrosineTyrosine 3-monooxygenasetarget
DB01089DeserpidineSynaptic vesicular amine transportertarget
DB01180RescinnamineAngiotensin-converting enzymetarget
DB06268SitaxentanCytochrome P450 2C19enzyme
DB06268SitaxentanCytochrome P450 2C9enzyme
DB06268SitaxentanCytochrome P450 3A4enzyme
DB06268SitaxentanEndothelin-1 receptortarget
DB06268SitaxentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin-1 receptortarget
DB06403AmbrisentanCytochrome P450 2C19enzyme
DB06403AmbrisentanCytochrome P450 3A4enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
DB06403AmbrisentanP-glycoprotein 1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
DB06403AmbrisentanCytochrome P450 3A5enzyme
DB08931RiociguatSerum albumincarrier
DB08931RiociguatAlpha-1-acid glycoprotein 1carrier
DB08931RiociguatGuanylate cyclase soluble subunit alpha-2target
DB08931RiociguatATP-binding cassette sub-family G member 2transporter
DB08931RiociguatCytochrome P450 1A1enzyme
DB08931RiociguatCytochrome P450 3A4enzyme
DB08931RiociguatCytochrome P450 2C8enzyme
DB08931RiociguatCytochrome P450 2J2enzyme
DB08932MacitentanCytochrome P450 3A4enzyme
DB08932MacitentanCytochrome P450 2C19enzyme
DB08932MacitentanEndothelin-1 receptortarget
DB08932MacitentanEndothelin B receptortarget
DB08932MacitentanSerum albumincarrier
DB00187EsmololBeta-1 adrenergic receptortarget
DB00187EsmololCytochrome P450 2D6enzyme
DB01297PractololBeta-1 adrenergic receptortarget
DB01297PractololCytochrome P450 2D6enzyme
DB13443EsatenololCytochrome P450 2D6enzyme
DB01295BevantololBeta-1 adrenergic receptortarget
DB01295BevantololBeta-2 adrenergic receptortarget
DB01295BevantololAlpha-1A adrenergic receptortarget
DB01295BevantololCytochrome P450 2D6enzyme
DB14068DexniguldipineP-glycoprotein 1target
DB14068DexniguldipineCytochrome P450 3A4enzyme
DB01162TerazosinAlpha-1A adrenergic receptortarget
DB01162TerazosinAlpha-1B adrenergic receptortarget
DB01162TerazosinAlpha-1D adrenergic receptortarget
DB01162TerazosinPotassium voltage-gated channel subfamily H member 2target
DB01162TerazosinPotassium voltage-gated channel subfamily H member 6target
DB01162TerazosinPotassium voltage-gated channel subfamily H member 7target
DB01162TerazosinP-glycoprotein 1transporter
DB01162TerazosinTransforming growth factor beta-1target
DB00373TimololBeta-1 adrenergic receptortarget
DB00373TimololBeta-2 adrenergic receptortarget
DB00373TimololCytochrome P450 2D6enzyme
DB00373TimololP-glycoprotein 1transporter
DB00373TimololCytochrome P450 2C19enzyme
DB00373TimololLysozymetarget
DB00521CarteololBeta-2 adrenergic receptortarget
DB00521CarteololBeta-1 adrenergic receptortarget
DB00521CarteololCytochrome P450 2D6enzyme
DB00571PropranololBeta-1 adrenergic receptortarget
DB00571PropranololBeta-2 adrenergic receptortarget
DB00571PropranololBeta-3 adrenergic receptortarget
DB00571Propranolol5-hydroxytryptamine receptor 1Atarget
DB00571Propranolol5-hydroxytryptamine receptor 1Btarget
DB00571PropranololCytochrome P450 1A2enzyme
DB00571PropranololCytochrome P450 2D6enzyme
DB00571PropranololAlpha-1-acid glycoprotein 1carrier
DB00571PropranololCytochrome P450 2C19enzyme
DB00571PropranololCytochrome P450 3A4enzyme
DB00571PropranololCytochrome P450 3A5enzyme
DB00571PropranololCytochrome P450 3A7enzyme
DB00571PropranololSolute carrier family 22 member 2transporter
DB00571PropranololP-glycoprotein 1transporter
DB00571PropranololCytochrome P450 1A1enzyme
DB00571PropranololAmine oxidase [flavin-containing] Aenzyme
DB00571PropranololSerum albumincarrier
DB00866AlprenololBeta-1 adrenergic receptortarget
DB00866AlprenololBeta-2 adrenergic receptortarget
DB00866Alprenolol5-hydroxytryptamine receptor 1Atarget
DB00866AlprenololCytochrome P450 2D6enzyme
DB00866AlprenololBeta-3 adrenergic receptortarget
DB00960PindololBeta-1 adrenergic receptortarget
DB00960PindololBeta-2 adrenergic receptortarget
DB00960Pindolol5-hydroxytryptamine receptor 1Atarget
DB00960Pindolol5-hydroxytryptamine receptor 1Btarget
DB00960PindololCytochrome P450 2D6enzyme
DB00960PindololBeta-3 adrenergic receptortarget
DB01203NadololBeta-1 adrenergic receptortarget
DB01203NadololBeta-2 adrenergic receptortarget
DB01203NadololP-glycoprotein 1transporter
DB01203NadololPOU domain, class 2, transcription factor 1transporter
DB01203NadololPOU domain, class 2, transcription factor 2transporter
DB01203NadololMultidrug and toxin extrusion protein 1transporter
DB01203NadololMultidrug and toxin extrusion protein 2transporter
DB01203Nadololalpha1-acid glycoproteincarrier
DB01359PenbutololAlpha-1-acid glycoprotein 1carrier
DB01359PenbutololBeta-1 adrenergic receptortarget
DB01359PenbutololBeta-2 adrenergic receptortarget
DB01359Penbutolol5-hydroxytryptamine receptor 1Atarget
DB01359Penbutolol5-hydroxytryptamine receptor 1Btarget
DB01359PenbutololCytochrome P450 2D6enzyme
DB01580OxprenololBeta-1 adrenergic receptortarget
DB01580OxprenololBeta-2 adrenergic receptortarget
DB01580OxprenololSolute carrier family 22 member 2transporter
DB01580OxprenololCytochrome P450 2D6enzyme
DB01580OxprenololBeta-3 adrenergic receptortarget
DB08808BupranololBeta-1 adrenergic receptortarget
DB08808BupranololBeta-2 adrenergic receptortarget
DB08808BupranololBeta-3 adrenergic receptortarget
DB08808BupranololCytochrome P450 2D6enzyme
DB13508CloranololCytochrome P450 2D6enzyme
DB09363Rauwolfia serpentina rootSynaptic vesicular amine transportertarget
DB09363Rauwolfia serpentina rootMonoamine oxidaseenzyme
DB09363Rauwolfia serpentina rootSodium-dependent noradrenaline transportertransporter
DB09363Rauwolfia serpentina rootvesicular monoamine transporter 2 (VMAT2)transporter
DB00727NitroglycerinAtrial natriuretic peptide receptor 1target
DB00727NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB12212LandiololCytochrome P450 2D6enzyme
DB00700EplerenoneMineralocorticoid receptortarget
DB00700EplerenoneCytochrome P450 3A4enzyme
DB00700EplerenoneCytochrome P450 3A5enzyme
DB00700EplerenoneCytochrome P450 11B2, mitochondrialenzyme
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB15565CilazaprilatAngiotensin-converting enzymetarget