| DB00187 | Esmolol | For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention. |
| DB00195 | Betaxolol | For the management of hypertension. |
| DB00264 | Metoprolol | For the management of acute myocardial infarction, angina pectoris, heart failure and mild to moderate hypertension. May be used to treat supraventricular and tachyarrhythmias and as prophylaxis for migraine headaches. |
| DB00298 | Dapiprazole | Used in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations. |
| DB00335 | Atenolol | For the management of hypertention and long-term management of patients with angina pectoris |
| DB00346 | Alfuzosin | For the reduction of urinary obstruction and relief of associated manifestations (eg. sensation of incomplete bladder emptying or straining, urgency, interrupted or weak stream) in patients with symptomatic beningn prostatic hyperplasia. |
| DB00370 | Mirtazapine | For the treatment of major depressive disorder. |
| DB00373 | Timolol | In its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma. |
| DB00392 | Ethopropazine | For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine. |
| DB00457 | Prazosin | For treatment of hypertension, symptomatic benign prostatic hyperplasia, and severe congestive heart failure. May also be used alone or in combination with β-blockers in the preoperative management of signs and symptoms of pheochromocytoma. |
| DB00489 | Sotalol | For the maintenance of normal sinus rhythm [delay in time to recurrence of atrial fibrillation/atrial flutter (AFIB/AFL)] in patients with symptomatic AFIB/AFL who are currently in sinus rhythm. Also for the treatment of documented life-threatening ventricular arrhythmias. |
| DB00521 | Carteolol | For the treatment of intraocular hypertension and chronic open-angle glaucoma |
| DB00571 | Propranolol | For the prophylaxis of migraine. |
| DB00590 | Doxazosin | For treatment and management of mild to moderate hypertension and urinary obstruction symptoms caused by BPH. |
| DB00598 | Labetalol | For the management of hypertension (alone or in combination with other classes of antihypertensive agents), as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency, for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia, and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures. |
| DB00612 | Bisoprolol | For management of heart failure, angina pectoris, and mild to moderate hypertension and for secondary prevention of myocardial infarction (MI). |
| DB00692 | Phentolamine | Used as an aid for the diagnosis of pheochromocytoma, and may be administered immediately prior to or during pheochromocytomectomy to prevent or control paroxysmal hypertension resulting from anesthesia, stress, or operative manipulation of the tumor. Phentolamine has also been used to treat hypertensive crisis caused by sympathomimetic amines or catecholamine excess by certain foods or drugs in patients taking MAO inhibitors, or by clonidine withdrawal syndrome. Other indications include the prevention of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine, decrease in impedance to left ventricular ejection and the infarct size in patients with MI associated with left ventricular failure, treatment of erectile dysfunction through self-injection of small doses combined with papaverine hydrochloride into the corpus cavernosum, and as an adjunct to the management of cocaine overdose to reverse coronary vasoconstriction following use of oxygen, benzodiazepines,and nitroglycerin. |
| DB00699 | Nicergoline | For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration. |
| DB00706 | Tamsulosin | Used in the treatment of signs and symptoms of benign prostatic hyperplasia (reduction in urinary obstruction and relief of associated manifestations such as hesitancy, terminal dribbling of urine, interrupted or weak stream...etc.) |
| DB00797 | Tolazoline | For the treatment of pulmonary artery anomalies |
| DB00866 | Alprenolol | For the treatment of hypertension, angina, and arrhythmia |
| DB00908 | Quinidine | For the treatment of ventricular pre-excitation and cardiac dysrhythmias |
| DB00925 | Phenoxybenzamine | For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension. |
| DB00960 | Pindolol | For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. |
| DB01049 | Ergoloid mesylate | It was labeled by the FDA for the treatment of symptoms of an idiopathic decline in the mental capacity not related to a potentially reversible condition[A32913] as well as for age-related cognitive impairment.[A32926] The prescription of this drug is conditioned to the corroboration that the patient is not suffering from a potentially reversible and treatable condition especially delirium and dementiform illness secondary to systemic disease, primary neurological disease or primary mood disturbance.[L2637] To know more about the individual components of the ergoloid mixture, please visit [DB13345] and [DB11274] |
| DB01136 | Carvedilol | For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. |
| DB01158 | Bretylium | For use in the prophylaxis and therapy of ventricular fibrillation. Also used in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia, that have failed to respond to adequate doses of a first-line antiarrhythmic agent, such as lidocaine. |
| DB01162 | Terazosin | For the treatment of symptomatic BPH and mild to moderate hypertension. |
| DB01193 | Acebutolol | For the management of hypertension and ventricular premature beats in adults. |
| DB01203 | Nadolol | Used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension. |
| DB01210 | Levobunolol | For lowering intraocular pressure (IOP) and may be used in patients with chronic open-angle glaucoma or ocular hypertension. |
| DB01214 | Metipranolol | Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma. |
| DB01295 | Bevantolol | For the treatment of angina pectoris and hypertension. |
| DB01297 | Practolol | Used in the emergency treatment of cardiac arrhythmias. |
| DB01359 | Penbutolol | Penbutolol is indicated in the treatment of mild to moderate arterial hypertension. It may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. |
| DB01392 | Yohimbine | Indicated as a sympatholytic and mydriatic. Impotence has been successfully treated with yohimbine in male patients with vascular or diabetic origins and psychogenic origins. |
| DB01580 | Oxprenolol | Used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety. |
| DB04581 | 1-benzylimidazole | Not Available |
| DB04846 | Celiprolol | Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. |
| DB06148 | Mianserin | For the treatment of depression. |
| DB06207 | Silodosin | Treatment for symptomatic relief of benign prostatic hyperplasia |
| DB06678 | Esmirtazapine | Investigated for use/treatment in insomnia and sleep disorders. |
| DB06726 | Bufuralol | Not Available |
| DB08807 | Bopindolol | For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. |
| DB08808 | Bupranolol | Used to manage hypertension and tachycardia. Also used to treat glaucoma. |
| DB08815 | Lurasidone | Treatment of schizophrenia. |
| DB08950 | Indoramin | Not Available |
| DB08952 | Indenolol | Not Available |
| DB08954 | Ifenprodil | Not Available |
| DB09013 | Befunolol | Used in the management of open angle glaucoma. PMID: 12480285. |
| DB09204 | Arotinolol | Artinolol was introduced to be used as an antihypertensive agent since 1986.[T88] It has been studied for other functions like tremor control for patients with Parkinson disease and it is currently in clinical trials for its use in the control of blood pressure and heart rate.[L1168] |
| DB09205 | Moxisylyte | By the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage.[T91] The cerebral infarction is characterized by the blockage of the artery either by the formation of a thrombus or an embolus.[A31644]
On the other hand, the FDA classified moxisylyte for the reversal of phenylephrine-induced mydriasis in patients who have narrow anterior angles and are at risk of developing an acute attack of angle-closure glaucoma.[L1172] Closed-angle glaucoma is caused by the contact between the iris and the trabecular meshwork. This contact will damage the aqueous outflow by the meshwork thus, increasing eye pressure and producing the symptoms of glaucoma.[A31645] Mydriasis is referred to the dilatation of the pupils and this standard body function is known to be a trigger factor for the development of acute closed-angle glaucoma.This risk is explained by the generation of a pupillary block, which is the contact between the pupillary margins and the lens, thus preventing flow from the aqueous humor to the anterior chamber and followed by an increased pressure gradient.[L1173]
Moxisylyte is also approved in France as the first drug for the treatment of impotence.[A31647] |
| DB09206 | Trimazosin | Not Available |
| DB11481 | Atipamezole | For the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. |
| DB11770 | Talinolol | Not Available |
| DB12092 | Naftopidil | Not Available |
| DB12212 | Landiolol | Not Available |
| DB12230 | Bunazosin | Not Available |
| DB12551 | Idazoxan | Not Available |
| DB12661 | Urapidil | Not Available |
| DB12752 | Bucindolol | Not Available |
| DB13345 | Dihydroergocristine | Dihydroergocristine is used in some countries such as Brasil as a single agent for the treatment of cerebral and peripheric vascular events.[L2649] To know more about dihydroergocristine as part of the ergoloid mesylate mixture, please visit [DB01049]. |
| DB13508 | Cloranolol | Not Available |
| DB13530 | Mepindolol | Not Available |
| DB13757 | Epanolol | Not Available |
| DB13775 | Tertatolol | Not Available |
| DB04861 | Nebivolol | For the treatment of essential hypertension. |
| DB13443 | Esatenolol | Not Available |
| DB06216 | Asenapine | Used for treatment in psychosis, schizophrenia and schizoaffective disorders, manic disorders, and bipolar disorders as monotherapy or in combination. |
| DB01182 | Propafenone | Used to prolong the time to recurrence of paroxysmal atrial fibrillation/flutter (PAF) associated with disabling symptoms in patients without structural heart disease. Also used for the treatment of life-threatening documented ventricular arrhythmias, such as sustained ventricular tachycardia. |
| DB09351 | Levobetaxolol | Used in the treatment of open-angle glaucoma and ocular hypertension [FDA Label]. |
| DB01126 | Dutasteride | For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland to improve symptoms, and reduce the risk of acute urinary retention and the need for surgery. |
| DB01216 | Finasteride | For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness). |
| DB01591 | Solifenacin | For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. |
| DB00246 | Ziprasidone | For the treatment of schizophrenia and related psychotic disorders. |
| DB00679 | Thioridazine | For the treatment of schizophrenia and generalized anxiety disorder. |
| DB00875 | Flupentixol | For use in the treatment of schizophrenia and depression |
| DB00420 | Promazine | Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly. |
| DB00656 | Trazodone | For the treatment of depression. |
| DB00734 | Risperidone | Risperidone belongs to the class of medications known as ​second generation atypical antipsychotics [A1114, A1115, L1213]. It is widely used in the treatment of schizophrenia and mood disorders, including bipolar disorder and depression with pyschosis [A1115, A1116, L1212, L1213]. |
| DB00777 | Propiomazine | Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia. |
| DB00831 | Trifluoperazine | For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation. |
| DB01149 | Nefazodone | For the treatment of depression. |
| DB01403 | Methotrimeprazine | For the treatment of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. |
| DB04855 | Dronedarone | Management of paroxysmal or persistent atrial fibrillation via restoration of normal sinus rhythm. |
| DB00622 | Nicardipine | Used for the management of patients with chronic stable angina and for the treatment of hypertension. |
| DB01267 | Paliperidone | For the treatment of schizophrenia. |
| DB01224 | Quetiapine | For the treatment of schizophrenia and related psychotic disorders. |
| DB00363 | Clozapine | For use in patients with treatment-resistant schizophrenia. |
| DB01238 | Aripiprazole | For the treatment of schizophrenia and related psychotic disorders. |
| DB00334 | Olanzapine | For the acute and maintenance treatment of schizophrenia and related psychotic disorders, as well as acute treatment of manic or mixed episodes of bipolar 1 disorder. Intramuscular olanzapine is indicated for the rapid control of agitated patients. |
| DB00450 | Droperidol | Droperidol is ssed to produce tranquilization and to reduce the incidence of nausea and vomiting in surgical and diagnostic procedures. |
| DB01624 | Zuclopenthixol | Used in the management of acute psychoses such as mania or schizophrenia. However, the use of zuclopenthixol acetate in psychiatric emergencies as an alternative to standard treatments (haloperidol, clotiapine, etc.) should be cautioned, since well executed and documented trials of zuclopenthixol acetate for this use have yet to be conducted. Zuclopenthixol acetate is not intended for long-term use. |
| DB00321 | Amitriptyline | - Indicated for the treatment of major depressive disorder in adults
- Indicated for the management of neuropathic pain in adults
- Indicated for the prophylactic treatment of chronic tension type headache (CTTH) in adults
- Indicated for the prophylactic treatment of migraine in adults
- Indicated for the the treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been excluded and no response has been achieved to all other non-drug and drug treatments, including antispasmodics and vasopressin-related products. This medicinal product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis.
-Other off-label uses include irritable bowel syndrome, sleep disorders, diabetic neuropathy, agitation and insomnia |
| DB01142 | Doxepin | **Oral: **
- Indicated for the treatment of depression and/or anxiety [FDA Label].
- Indicated for the treatment of depression and/or anxiety associated with different conditions, including alcoholism, organic disease and manic-depressive disorders [FDA Label].
- Indicated for the treatment of insomnia characterized by difficulties with sleep maintenance [L1347].
Topical:
- Indicated for the short-term (up to 8 days) management of moderate pruritus in adult patients with atopic dermatitis or lichen simplex chronicus [L1344]. |
| DB00458 | Imipramine | For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older [FDA Label].
May also be used off-label to manage panic disorders with or without agoraphobia, as a second line agent for ADHD in children and adolescents, to manage bulimia nervosa, for short-term management of acute depressive episodes in bipolar disorder and schizophrenia, for the treatment of acute stress disorder and posttraumatic stress disorder, and for symptomatic treatment of postherpetic neuralgia and painful diabetic neuropathy [L1349,L1348,A31900,L1351,L1352,L1353,A31904]. |
| DB00540 | Nortriptyline | Primarily indicated for the relief of symptoms of depression. |
| DB00543 | Amoxapine | For the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. May also be used to treat depression accompanied by anxiety or agitation. |
| DB00726 | Trimipramine | For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance |
| DB00477 | Chlorpromazine | For the treatment of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in the treatment of tetanus; to control the manifestations of the manic type of manic-depressive illness; for relief of intractable hiccups; for the treatment of severe behavioral problems in children (1 to 12 years of age) marked by combativeness and/or explosive hyperexcitable behavior (out of proportion to immediate provocations), and in the short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct disorders consisting of some or all of the following symptoms: impulsivity, difficulty sustaining attention, aggressivity, mood lability, and poor frustration tolerance. |
| DB01614 | Acepromazine | Acepromazine was first used in humans in the 1950s as an antipsychotic agent. It is now rarely used in humans. Acepromazine is frequently used in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious animals. |
| DB01622 | Thioproperazine | For the treatment of all types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes. |
| DB04946 | Iloperidone | Treatment of acute schizophrenia. |
| DB09239 | Niguldipine | Not Available |
| DB00661 | Verapamil | For the treatment of hypertension, angina, and cluster headache prophylaxis. |
| DB06153 | Pizotifen | Indicated for the prophylactic management of migraines [L2292]. |
| DB12278 | Propiverine | Indicated for symptomatic treatment of urinary incontinence and/or increased urinary frequency and urgency in patients with overactive bladder (OAB) [L2315]. Propiverine may also be used in patients with neurogenic bladder as a result of spinal cord injury [A32581]. |
| DB01608 | Propericiazine | For use as adjunctive medication in some psychotic patients. Propericiazine (Pericyazine)is used for the control of residual prevailing hostility, impulsiveness and aggressiveness. |
| DB09128 | Brexpiprazole | As an adjunctive treatment of major depressive disorder (MDD) and for treatment of schizophrenia. |
| DB01200 | Bromocriptine | For the treatment of galactorrhea due to hyperprolactinemia, prolactin-dependent menstrual disorders and infertility, prolactin-secreting adenomas, prolactin-dependent male hypogonadism, as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases, as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. |
| DB02261 | Platelet Activating Factor | Not Available |
| DB11785 | Anisodamine | Not Available |
| DB00696 | Ergotamine | For use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia". |
| DB00320 | Dihydroergotamine | For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. |
| DB14185 | Aripiprazole lauroxil | Aripiprazole lauroxil is indicated for the treatment of schizophrenia and related psychotic disorders. |