Potential QTc-Prolonging Agents

Agents associated with a possible risk of QTc prolongation.
DrugDrug NameDrug Indication
DB00104OctreotideFor treatment of acromegaly and reduction of side effects from cancer chemotherapy
DB00107OxytocinUsed for labor induction, augmentation of labor, postpartum abbreviation of third stage of labor, postpartum control of uterine bleeding, termination of pregnancy and for the evaluation of fetal respiratory capability. Oxytocin cannot be used for elective induction of labor, there must be a clear medical requirement.
DB00188BortezomibFor treatment of multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
DB00196FluconazoleFor the treatment of fungal infections.
DB00220NelfinavirUsed in combination with other antiviral drugs in the treatment of HIV in both adults and children.
DB00243RanolazineFor the treatment of chronic angina. It should be used in combination with amlodipine, beta-blockers or nitrates.
DB00270IsradipineFor the management of mild to moderate essential hypertension. It may be used alone or concurrently with thiazide-type diuretics.
DB00285VenlafaxineFor the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain.
DB00289AtomoxetineFor the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) alone or in combination with behavioral treatment, as an adjunct to psychological, educational, social, and other remedial measures.
DB00334OlanzapineFor the acute and maintenance treatment of schizophrenia and related psychotic disorders, as well as acute treatment of manic or mixed episodes of bipolar 1 disorder. Intramuscular olanzapine is indicated for the rapid control of agitated patients.
DB00344ProtriptylineFor the treatment of depression.
DB00346AlfuzosinFor the reduction of urinary obstruction and relief of associated manifestations (eg. sensation of incomplete bladder emptying or straining, urgency, interrupted or weak stream) in patients with symptomatic beningn prostatic hyperplasia.
DB00358MefloquineFor the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and resistant strains) or by Plasmodium vivax. Also for the prophylaxis of Plasmodium falciparum and Plasmodium vivax malaria infections, including prophylaxis of chloroquine-resistant strains of Plasmodium falciparum.
DB00370MirtazapineFor the treatment of major depressive disorder.
DB00374TreprostinilFor use as a continuous subcutaneous infusion or intravenous infusion (for those not able to tolerate a subcutaneous infusion) for the treatment of pulmonary arterial hypertension in patients with NYHA Class II-IV symptoms to diminish symptoms associated with exercise.
DB00398SorafenibSorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
DB00440TrimethoprimFor the treatment of urinary tract infections, uncomplicated pyelonephritis (with sulfamethoxazole) and mild acute prostatitis. May be used as pericoital (with sulfamethoxazole) or continuous prophylaxis in females with recurrent cystitis. May be used as an alternative to treat asymptomatic bacteriuria during pregnancy (only before the last 6 weeks of pregnancy). Other uses include: alternative agent in respiratory tract infections (otitis, sinusitus, bronchitis and pneumonia), treatment of Pneumocystis jirovecii pneumonia (acute or prophylaxis), Nocardia infections, and traveller's diarrhea.
DB00503RitonavirIndicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
DB00529FoscarnetFor the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.
DB00540NortriptylinePrimarily indicated for the relief of symptoms of depression.
DB00543AmoxapineFor the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. May also be used to treat depression accompanied by anxiety or agitation.
DB00557HydroxyzineFor symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
DB00582VoriconazoleFor the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.
DB00622NicardipineUsed for the management of patients with chronic stable angina and for the treatment of hypertension.
DB00656TrazodoneFor the treatment of depression.
DB00674GalantamineFor the treatment of mild to moderate dementia of the Alzheimer's type. Has also been investigated in patients with mild cognitive impairment who did not meet the diagnostic criteria for Alzheimer's disease.
DB00675TamoxifenTamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ.
DB00691MoexiprilFor the treatment of hypertension.
DB00697TizanidineFor the management of increased muscle tone associated with spasticity
DB00710IbandronateFor the treatment and prevention of osteoporosis in postmenopausal women.
DB00714ApomorphineFor the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
DB00715ParoxetineLabeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause.
DB00726TrimipramineFor the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
DB00734RisperidoneRisperidone belongs to the class of medications known as ​second generation atypical antipsychotics [A1114, A1115, L1213]. It is widely used in the treatment of schizophrenia and mood disorders, including bipolar disorder and depression with pyschosis [A1115, A1116, L1212, L1213].
DB00753IsofluraneFor induction and maintenance of general anesthesia.
DB00808IndapamideFor the treatment of hypertension, alone or in combination with other antihypertensive drugs, as well as for the treatment of salt and fluid retention associated with congestive heart failure or edema from pregnancy (appropriate only in the management of edema of pathologic origin during pregnancy when clearly needed). Also used for the management of edema as a result of various causes.
DB00818PropofolUsed for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
DB00862VardenafilUsed for the treatment of erectile dysfunction
DB00871TerbutalineFor the prevention and reversal of bronchospasm in patients 12 years of age and older with reversible, obstructive airway disease, as well as symptomatic management of reversible bronchospasm associated with bronchitis and emphysema. Also used acute IV and sub-Q therapy in selected women to inhibit uterine contractions in preterm labor (tocolysis) and prolong gestation when beneficial.
DB00915AmantadineFor the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.
DB00916MetronidazoleFor the treatment of anaerobic infections and mixed infections, surgical prophylaxis requiring anaerobic coverage, Clostridium difficile-associated diarrhea and colitis, Helicobacter pylori infection and duodenal ulcer disease, bacterial vaginosis, Giardia lamblia gastro-enteritis, amebiasis caused by Entamoeba histolytica, acne rosacea (topical treatment), and Trichomonas infections.
DB00927FamotidineFor the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
DB00934MaprotilineFor treatment of depression, including the depressed phase of bipolar depression, psychotic depression, and involutional melancholia, and may also be helpful in treating certain patients suffering severe depressive neurosis.
DB00938SalmeterolFor the treatment of asthma and chronic obstructive pulmonary disease (COPD).
DB00949FelbamateFor use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.
DB00983FormoterolFor use as long-term maintenance treatment of asthma in patients 6 years of age and older with reversible obstructive airways disease, including patients with symptoms of nocturnal asthma, who are using optimal corticosteroid treatment and experiencing regular or frequent breakthrough symptoms requiring use of a short-acting bronchodilator. Not indicated for asthma that can be successfully managed with occasional use of an inhaled, short-acting beta2-adrenergic agonist. Also used for the prevention of exercise-induced bronchospasm, as well as long-term treatment of bronchospasm associated with COPD.
DB01001SalbutamolFor symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, and other chronic bronchopulmonary disorders such as COPD.
DB01015SulfamethoxazoleFor the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
DB01026KetoconazoleFor the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
DB01036TolterodineFor the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
DB01059NorfloxacinFor the treatment of urinary tract infection
DB01069PromethazineFor the treatment of allergic disorders, and nausea/vomiting.
DB01072AtazanavirUsed in combination with other antiretroviral agents for the treatment of HIV-1 infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission.
DB01075DiphenhydramineFor the treatment of symptoms associated with Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite.
DB01104SertralineFor the management of major depressive disorder (MDD), posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD) with or without agoraphobia, premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD) [FDA Label]. It may be used for premature ejaculation and vascular headaches as off-label indications.
DB01142Doxepin**Oral: ** - Indicated for the treatment of depression and/or anxiety [FDA Label]. - Indicated for the treatment of depression and/or anxiety associated with different conditions, including alcoholism, organic disease and manic-depressive disorders [FDA Label]. - Indicated for the treatment of insomnia characterized by difficulties with sleep maintenance [L1347]. Topical: - Indicated for the short-term (up to 8 days) management of moderate pruritus in adult patients with atopic dermatitis or lichen simplex chronicus [L1344].
DB01151DesipramineFor relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
DB01167ItraconazoleFor the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
DB01189DesfluraneFor use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults.
DB01233MetoclopramideFor the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying.
DB01236SevofluraneUsed for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
DB01238AripiprazoleFor the treatment of schizophrenia and related psychotic disorders.
DB01254DasatinibFor the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.
DB01259LapatinibIndicated in combination with capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress the human epidermal receptor type 2 (HER2) protein and who have received prior therapy including an anthracycline, a taxane, and trastuzuma.
DB01263PosaconazoleFor prophylaxis of invasive Aspergillus and Candida infections in patients, 13 years of age and older, who are at high risk of developing these infections due to being severely immunocompromised as a result of procedures such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD), or due to hematologic malignancies with prolonged neutropenia from chemotherapy. Also for the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole. Posaconazole is used as an alternative treatment for invasive aspergillosis, Fusarium infections, and zygomycosis in patients who are intolerant of, or whose disease is refractory to, other antifungals.
DB01268SunitinibFor the treatment of advanced renal cell carcinoma as well as the treatment of gastrointestinal stromal tumor after disease progression on or intolerance to imatinib mesylate.
DB01274ArformoterolA bronchodilator used for the long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
DB01403MethotrimeprazineFor the treatment of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
DB01591SolifenacinFor the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.
DB01623ThiothixeneFor the management of schizophrenia.
DB02546VorinostatFor the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following two systemic therapies.
DB04953EzogabineAdjuvant treatment of partial-onset seizures.
DB05039IndacaterolFor the long term, once-daily-dosing maintenance of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DB06663PasireotideFor the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
DB06699DegarelixDegaralix is used for the management of advanced prostate cancer.
DB06719BuserelinBuserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.
DB06788HistrelinAs the product Supprelin LA (FDA), histrelin is indicated for the treatment of children with central precocious puberty (CPP). As the product Vantas (FDA), histrelin is indicated for the palliative treatment of advanced prostate cancer.
DB06825TriptorelinTriptorelin is indicated for the palliative treatment of advanced prostate cancer.
DB08864RilpivirineRilpivirine, in combination with other agents, is indicated for the treatment of HIV-1 infections in antiretroviral treatment-naive patients with HIV-1 RNA ≤100,000 copies/mL and CD4+ cell count >200 cells/mm3.[L1030] The FDA combination therapy approval of rilpivirine and dolutegravir is indicated for adults with HIV-1 infections whose virus is currently suppressed (< 50 copies/ml) on a stable regimen for at least six months, without history of treatment failure and no known substitutions associated to resistance to any of the two components of the therapy.[L1031]
DB08868FingolimodFingolimod is a sphingosine 1-phosphate receptor modulator indicated for the treatment of patients with relapsing forms of multiple sclerosis to reduce the frequency of clinical exacerbations and to delay the accumulation of physical disability.
DB08871EribulinFor the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic cancer.
DB08893MirabegronMirabegron is a beta-3 adrenergic agonist indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.
DB08912DabrafenibTafinlar is a kinase inhibitor that was initially indicated as a single agent for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test [FDA label]. Tafinlar in combination with [DB08911] is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test. The use in combination is based on the demonstration of durable response rate. Improvement in disease-related symptoms or overall survival has not been demonstrated for Tafinlar in combination with trametinib [FDA label]. In May 2018, Tafinlar (dabrafenib) and Mekinist ([DB08911]) have been approved in combination to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene [L2712].
DB09080OlodaterolOlodaterol is indicated for use in chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. It is not indicated for the treatment of acute exacerbations of COPD or for the treatment of asthma.
DB09082VilanterolVilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
DB01071MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
DB00613AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
DB11891CUDC-907Not Available
DB12645GivinostatNot Available
DB05465TandutinibInvestigated for use/treatment in leukemia (myeloid).
DB00467EnoxacinFor the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria gonorrhoeae, (2) uncomplicated urinary tract infections (cystitis) due to Escherichia coli, Staphylococcus epidermidis, or Staphylococcus saprophyticus, and (3) complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus epidermidis, or Enterobacter cloacae.
DB04576FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
DB08972FlumequineNot Available
DB11774PazufloxacinNot Available
DB00487PefloxacinFor the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
DB11892PrulifloxacinNot Available
DB00817RosoxacinFor the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
DB13772RufloxacinNot Available
DB11491SarafloxacinNot Available
DB01166CilostazolFor the reduction of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).
DB00843DonepezilFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
DB01044GatifloxacinFor the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes
DB01611HydroxychloroquineFor the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis.
DB09488AcrivastineFor the relief of symptoms associated with seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.
DB06766AlcaftadineFor the prevention of itching associated with allergic conjunctivitis.
DB01246AlimemazineUsed to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).
DB14185Aripiprazole lauroxilAripiprazole lauroxil is indicated for the treatment of schizophrenia and related psychotic disorders.
DB00719AzatadineFor the relief of the symptoms of upper respiratory mucosal congestion in perennial and allergic rhinitis, and for the relief of nasal congestion and eustachian t.b. congestion.
DB00972AzelastineFor the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis.
DB00245BenzatropineFor use as an adjunct in the therapy of all forms of parkinsonism and also for use in the control of extrapyramidal disorders due to neuroleptic drugs.
DB11591BilastineFor symptomatic relief of nasal and non-nasal symptoms of seasonal rhinitis in patients 12 years of age and older and for symptomatic relief in chronic spontaneous urticaria in patients 18 years of age and older [FDA Label].
DB00354BuclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
DB00341CetirizineFor the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
DB08936ChlorcyclizineNot Available
DB01239ChlorprothixeneFor treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
DB01176CyclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
DB00434CyproheptadineFor treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.
DB00405DexbrompheniramineFor treatment and relief of symptoms of allergies, hay fever, and colds
DB09167DosulepinIndicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.
DB00366DoxylamineUsed alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
DB11742EbastineNot Available
DB00751EpinastineFor the prevention of itching associated with allergic conjunctivitis.
DB00920KetotifenIndicated as an add-on or prophylactic oral medication in the chronic treatment of mild atopic asthmatic children. Also used as self-medication for the temporary relief of itching of the eye due to allergic conjunctivitis (ophthalmic).
DB01106LevocabastineAs an ophthalmic for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. Also used as a nasal spray for allergic rhinitis.
DB06282LevocetirizineLevocetirizine is indicated for the relief of symptoms associated with allergic rhinitis (seasonal and perennial) in adults and children 6 years of age and older.
DB06691MepyramineMepyramine is a first generation antihistamine used in treating allergies, ymptomatic relief of hypersensitivity reaction, and in pruritic skin disorders.
DB00768OlopatadineFor the treatment of ocular itching associated with allergic conjunctivitis.
DB01173OrphenadrineIndicated for the treatment of Parkinson's disease.
DB01620PheniraminePheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria.
DB11614RupatadineFor the symptomatic relief of nasal and non-nasal symptoms of seasonal allergic rhinitis and perennial allergic rhinitis in patients 2 years of age and older [FDA Label]. Also used for the symptomatic relief of chronic spontaneous urticaria in patients 2 years of age and older.
DB00427TriprolidineFor the symptomatic relief of seasonal or perennial allergic rhinitis or nonallergic rhinitis; allergic conjunctivitis; and mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Also used in combination with other agents for the symptomatic relief of symptoms associated with the common cold.
DB00835BrompheniramineFor the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.
DB01426AjmalineFor use as an antiarrhythmic agent.
DB00381AmlodipineFor the treatment of hypertension and chronic stable angina.
DB11785AnisodamineNot Available
DB09229AranidipineAranidipine has been used for many years to treat angina pectoris and hypertension.[A31895]
DB13488BencyclaneNot Available
DB01158BretyliumFor use in the prophylaxis and therapy of ventricular fibrillation. Also used in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia, that have failed to respond to adequate doses of a first-line antiarrhythmic agent, such as lidocaine.
DB08808BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
DB06468CariporideInvestigated for use/treatment in cardiac surgery.
DB00521CarteololFor the treatment of intraocular hypertension and chronic open-angle glaucoma
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB12766CicletanineNot Available
DB00390DigoxinFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB01396DigitoxinFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB00661VerapamilFor the treatment of hypertension, angina, and cluster headache prophylaxis.
DB09235EfonidipineFor the treatment of hypertension.
DB01228EncainideEncainide is a class Ic antiarrhythmic agent which was used for management of irregular heartbeats, such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation.
DB00187EsmololFor the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention.
DB00593EthosuximideFor the treatment of petit mal epilepsy.
DB01023FelodipineFor the treatment of mild to moderate essential hypertension.
DB00996GabapentinFor the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.
DB12923GallopamilNot Available
DB00424HyoscyamineFor treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
DB08952IndenololNot Available
DB09236LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors [L1126].
DB00555LamotrigineIndicated as adjunctive therapy for the following seizure types in patients ≥2 years of age: partial seizures/primary generalized tonic-clonic seizures/generalized seizures of Lennox-Gastaut syndrome [FDA Label]. Indicated for conversion to monotherapy in adults (≥16 years of age) with partial seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single antiepileptic drug (AED)[FDA Label]. Indicated for the maintenance treatment of Bipolar I Disorder to delay the time to occurrence of mood episodes (depression, mania, hypomania, mixed episodes) in adults (≥18 years of age) treated for acute mood episodes with standard therapy [FDA Label].
DB01202LevetiracetamUsed as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy.
DB00678LosartanMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00825MentholUsed to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
DB05246MethsuximideFor the control of absence (petit mal) seizures that are refractory to other drugs.
DB00680MoricizineUsed to treat irregular heartbeats (arrhythmias) and maintain a normal heart rate.
DB09239NiguldipineNot Available
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01074PerhexilineFor the management of severe angina pectoris.
DB12712PilsicainideNot Available
DB09090PinaveriumIndicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) associated with abdominal pain, bowel disturbances and intestinal discomfort, as well as the treatment of symptoms related to functional disorders of the biliary tract.
DB00230PregabalinPregabalin is used for the management of neuropathic pain associated with diabetic peripheral neuropathy or spinal cord injury, and postherpetic neuralgia. It is not approved for the management of fibromyalgia or as adjuntive therapy for adult partial onset seizures.[FDA label]
DB11770TalinololNot Available
DB12093TetrahydropalmatineNot Available
DB00373TimololIn its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma.
DB09089TrimebutineIndicated for symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
DB00347TrimethadioneUsed in the control of absence (petit mal) seizures that are refractory to treatment with other medications.
DB06217VernakalantIndicated for the rapid conversion of recent onset of atrial fibrillation to sinus rhythm in adults for non-surgery patients that lasts for less than 7 days of duration and post-cardiac surgery patients with atrial fibrillation lasting less than 3 days of duration.
DB06283ZiconotideNot Available
DB00909ZonisamideFor use as adjunctive treatment of partial seizures in adults with epilepsy.
DrugDrug NameTargetType
DB00104OctreotideSomatostatin receptor type 1target
DB00104OctreotideSomatostatin receptor type 5target
DB00104OctreotideSomatostatin receptor type 2target
DB00104OctreotideMyeloperoxidaseenzyme
DB00104OctreotideCytochrome P450 3A4enzyme
DB00107OxytocinOxytocin-neurophysin 1target
DB00107OxytocinOxytocin receptortarget
DB00107OxytocinProlyl endopeptidaseenzyme
DB00188BortezomibCytochrome P450 3A4enzyme
DB00188BortezomibCytochrome P450 2C19enzyme
DB00188BortezomibCytochrome P450 1A2enzyme
DB00188BortezomibCytochrome P450 2D6enzyme
DB00188BortezomibCytochrome P450 2C9enzyme
DB00188BortezomibProteasome subunit beta type-5target
DB00188BortezomibProteasome subunit beta type-1target
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleCytochrome P450 3A5enzyme
DB00196FluconazoleCytochrome P450 3A7enzyme
DB00196FluconazoleMultidrug resistance protein 1transporter
DB00196FluconazoleLanosterol 14-alpha demethylasetarget
DB00196FluconazoleCytochrome P450 11B1, mitochondrialenzyme
DB00196FluconazoleCytochrome P450 1A2enzyme
DB00220NelfinavirHIV-1 proteasetarget
DB00220NelfinavirCytochrome P450 2C19enzyme
DB00220NelfinavirCytochrome P450 3A4enzyme
DB00220NelfinavirCytochrome P450 2B6enzyme
DB00220NelfinavirCytochrome P450 3A5enzyme
DB00220NelfinavirCytochrome P450 3A7enzyme
DB00220NelfinavirMultidrug resistance protein 1transporter
DB00220NelfinavirSolute carrier family 22 member 1transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1A2transporter
DB00220NelfinavirATP-binding cassette sub-family G member 2transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1B1transporter
DB00220NelfinavirCytochrome P450 1A2enzyme
DB00220NelfinavirCytochrome P450 2C9enzyme
DB00220NelfinavirCytochrome P450 2D6enzyme
DB00220NelfinavirSerum albumincarrier
DB00220NelfinavirUDP-glucuronosyltransferase 1-1enzyme
DB00220NelfinavirSolute carrier organic anion transporter family member 1B3transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 2B1transporter
DB00220NelfinavirBile salt export pumptransporter
DB00243RanolazineCytochrome P450 3A4enzyme
DB00243RanolazineCytochrome P450 2D6enzyme
DB00243RanolazineSodium channel protein type 5 subunit alphatarget
DB00243RanolazineSodium channel protein type 9 subunit alphatarget
DB00243RanolazineBile salt export pumptransporter
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00270IsradipineCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00270IsradipineBile salt export pumptransporter
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineCytochrome P450 2C9enzyme
DB00285VenlafaxineCytochrome P450 2C19enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineMultidrug resistance protein 1transporter
DB00285VenlafaxineCytochrome P450 2B6enzyme
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DB00289AtomoxetineSodium-dependent noradrenaline transportertarget
DB00289AtomoxetineCytochrome P450 2D6enzyme
DB00289AtomoxetineSodium-dependent serotonin transportertarget
DB00289AtomoxetineCytochrome P450 2C19enzyme
DB00289AtomoxetineCytochrome P450 3A4enzyme
DB00289AtomoxetineSodium-dependent dopamine transportertarget
DB00289AtomoxetineNMDA receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M5target
DB00334OlanzapineD(1A) dopamine receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineD(4) dopamine receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineD(2) dopamine receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineD(3) dopamine receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 1Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Dtarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Etarget
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334Olanzapine5-hydroxytryptamine receptor 7target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineAlpha-2A adrenergic receptortarget
DB00334OlanzapineAlpha-2B adrenergic receptortarget
DB00334OlanzapineAlpha-2C adrenergic receptortarget
DB00334OlanzapineD(1B) dopamine receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineMultidrug resistance protein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 2Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 5Atarget
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineHistamine H2 receptortarget
DB00334OlanzapineHistamine H4 receptortarget
DB00334OlanzapineGABA-A receptor (anion channel)target
DB00334OlanzapineBeta adrenergic receptortarget
DB00334OlanzapineD(2L) dopamine receptortarget
DB00334OlanzapineD(2S) dopamine receptortarget
DB00334OlanzapineUDP-glucuronosyltransferase 1-1enzyme
DB00344ProtriptylineSodium-dependent noradrenaline transportertarget
DB00344ProtriptylineSodium-dependent serotonin transportertarget
DB00344ProtriptylineCytochrome P450 2D6enzyme
DB00344ProtriptylineMultidrug resistance protein 1transporter
DB00346AlfuzosinAlpha-1A adrenergic receptortarget
DB00346AlfuzosinAlpha-1B adrenergic receptortarget
DB00346AlfuzosinAlpha-1D adrenergic receptortarget
DB00346AlfuzosinCytochrome P450 3A4enzyme
DB00346AlfuzosinPotassium voltage-gated channel subfamily H member 2target
DB00358MefloquineHemoglobin subunit alphatarget
DB00358MefloquineCholinesteraseenzyme
DB00358MefloquineCytochrome P450 3A4enzyme
DB00358MefloquineAdenosine receptor A2atarget
DB00358MefloquineFe(II)-protoporphyrin IXtarget
DB00358MefloquineMultidrug resistance protein 1transporter
DB00358MefloquineCytochrome P450 19A1enzyme
DB00358MefloquineCytochrome P450 2D6enzyme
DB00358MefloquineAcetylcholinesteraseenzyme
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5-hydroxytryptamine receptor 3Atarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineCytochrome P450 2C8enzyme
DB00370MirtazapineCytochrome P450 2C9enzyme
DB00370MirtazapineAlpha-2C adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 7target
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineD(2) dopamine receptortarget
DB00370MirtazapineD(3) dopamine receptortarget
DB00370MirtazapineSodium-dependent noradrenaline transportertarget
DB00370MirtazapineSodium-dependent serotonin transportertarget
DB00370MirtazapineSodium-dependent dopamine transportertarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Btarget
DB00370MirtazapineD(1) dopamine receptortarget
DB00370MirtazapineHistamine H3 receptortarget
DB00370MirtazapineAlpha-1A adrenergic receptortarget
DB00370MirtazapineBeta-1 adrenergic receptortarget
DB00370MirtazapineBeta-2 adrenergic receptortarget
DB00374TreprostinilP2Y purinoceptor 12target
DB00374TreprostinilPeroxisome proliferator-activated receptor deltatarget
DB00374TreprostinilProstacyclin receptortarget
DB00374TreprostinilCytochrome P450 2C9enzyme
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibMultidrug resistance protein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB00440TrimethoprimThymidylate synthasetarget
DB00440TrimethoprimDihydrofolate reductasetarget
DB00440TrimethoprimCytochrome P450 2C8enzyme
DB00440TrimethoprimCytochrome P450 2C9enzyme
DB00440TrimethoprimCytochrome P450 3A4enzyme
DB00440TrimethoprimMultidrug resistance protein 1transporter
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirMultidrug resistance protein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetSolute carrier family 22 member 6transporter
DB00529FoscarnetMonocarboxylate transporter 1transporter
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineCytochrome P450 2C9enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineD(2) dopamine receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DB00543AmoxapineSodium-dependent serotonin transportertarget
DB00543AmoxapineSodium-dependent noradrenaline transportertarget
DB00543AmoxapineAlpha-2A adrenergic receptortarget
DB00543AmoxapineD(2) dopamine receptortarget
DB00543AmoxapineAlpha-1A adrenergic receptortarget
DB00543AmoxapineD(1A) dopamine receptortarget
DB00543AmoxapineMuscarinic acetylcholine receptor M1target
DB00543AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
DB00543AmoxapineAlpha-1-acid glycoprotein 1carrier
DB00543AmoxapineCytochrome P450 2D6enzyme
DB00543Amoxapine5-hydroxytryptamine receptor 2Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Ctarget
DB00543Amoxapine5-hydroxytryptamine receptor 6target
DB00543Amoxapine5-hydroxytryptamine receptor 7target
DB00543AmoxapineD(3) dopamine receptortarget
DB00543AmoxapineD(4) dopamine receptortarget
DB00543AmoxapineHistamine H1 receptortarget
DB00543AmoxapineAlpha-1 adrenergic receptorstarget
DB00543AmoxapineMuscarinic acetylcholine receptortarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Btarget
DB00543Amoxapine5-hydroxytryptamine receptor 3Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Btarget
DB00543AmoxapineAlpha-2 adrenergic receptorstarget
DB00543AmoxapineHistamine H4 receptortarget
DB00543AmoxapineGABA-A receptor (anion channel)target
DB00543AmoxapineSodium-dependent dopamine transportertarget
DB00557HydroxyzineHistamine H1 receptortarget
DB00557HydroxyzineCytochrome P450 2D6enzyme
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleLanosterol 14-alpha demethylasetarget
DB00582VoriconazoleCytochrome P450 2B6enzyme
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C9enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineMultidrug resistance protein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneAlpha-1-acid glycoprotein 1carrier
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656TrazodoneMultidrug resistance protein 1transporter
DB00674GalantamineAcetylcholinesterasetarget
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00674GalantamineCholinesterasetarget
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00675TamoxifenBile salt export pumptransporter
DB00691MoexiprilAngiotensin-converting enzymetarget
DB00691MoexiprilSolute carrier family 15 member 1transporter
DB00691MoexiprilSolute carrier family 15 member 2transporter
DB00691MoexiprilAngiotensin-converting enzyme 2target
DB00697TizanidineAlpha-2A adrenergic receptortarget
DB00697TizanidineCytochrome P450 1A2enzyme
DB00697TizanidineAlpha-2B adrenergic receptortarget
DB00697TizanidineAlpha-2C adrenergic receptortarget
DB00697TizanidineNischarintarget
DB00710IbandronateFarnesyl pyrophosphate synthasetarget
DB00710IbandronateHydroxylapatitetarget
DB00714ApomorphineD(2) dopamine receptortarget
DB00714ApomorphineD(1A) dopamine receptortarget
DB00714ApomorphineD(4) dopamine receptortarget
DB00714ApomorphineD(3) dopamine receptortarget
DB00714ApomorphineD(1B) dopamine receptortarget
DB00714ApomorphineNeuron-specific vesicular protein calcyontarget
DB00714ApomorphineAlpha-2C adrenergic receptortarget
DB00714ApomorphineAlpha-2B adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Ctarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Btarget
DB00714ApomorphineAlpha-2A adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Dtarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Btarget
DB00714ApomorphineCytochrome P450 1A2enzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineMuscarinic acetylcholine receptor M1target
DB00715ParoxetineMuscarinic acetylcholine receptor M2target
DB00715ParoxetineMuscarinic acetylcholine receptor M3target
DB00715ParoxetineMuscarinic acetylcholine receptor M4target
DB00715ParoxetineMuscarinic acetylcholine receptor M5target
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineMultidrug resistance protein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 2C8enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00726TrimipramineSodium-dependent serotonin transportertarget
DB00726TrimipramineSodium-dependent noradrenaline transportertarget
DB00726TrimipramineCytochrome P450 2D6enzyme
DB00726TrimipramineSodium-dependent dopamine transportertarget
DB00726Trimipramine5-hydroxytryptamine receptor 2Atarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Atarget
DB00726TrimipramineAlpha-1A adrenergic receptortarget
DB00726TrimipramineAlpha-1B adrenergic receptortarget
DB00726TrimipramineD(2) dopamine receptortarget
DB00726TrimipramineAlpha-2B adrenergic receptortarget
DB00726TrimipramineHistamine H1 receptortarget
DB00726TrimipramineCytochrome P450 2C19enzyme
DB00726TrimipramineCytochrome P450 3A4enzyme
DB00726TrimipramineMultidrug resistance protein 1transporter
DB00726TrimipramineCytochrome P450 2C9enzyme
DB00726Trimipramine5-hydroxytryptamine receptor 2Ctarget
DB00726Trimipramine5-hydroxytryptamine receptor 3Atarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Dtarget
DB00726TrimipramineAlpha-2A adrenergic receptortarget
DB00726TrimipramineD(1) dopamine receptortarget
DB00726TrimipramineBeta adrenergic receptortarget
DB00726TrimipramineMuscarinic acetylcholine receptortarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Ctarget
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneD(2) dopamine receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneD(1A) dopamine receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneD(3) dopamine receptortarget
DB00734RisperidoneD(4) dopamine receptortarget
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734RisperidoneCytochrome P450 3A5enzyme
DB00734RisperidoneCytochrome P450 3A7enzyme
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB00753IsofluraneCalcium-transporting ATPase type 2C member 1target
DB00753IsofluraneATP synthase subunit delta, mitochondrialtarget
DB00753IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB00753IsofluranePotassium voltage-gated channel subfamily A member 1target
DB00753IsofluraneGlutamate receptor 1target
DB00753IsofluraneGlycine receptor subunit alpha-1target
DB00753IsofluraneCalmodulintarget
DB00753IsofluraneCytochrome P450 2E1enzyme
DB00753IsofluraneSerum albumincarrier
DB00753IsofluraneCytochrome P450 2B6enzyme
DB00753IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
DB00753IsofluraneGABA-A receptor (anion channel)target
DB00753IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
DB00753IsofluraneNeuronal acetylcholine receptor subunit beta-2target
DB00808IndapamideCytochrome P450 3A4enzyme
DB00808IndapamideSolute carrier family 12 member 3target
DB00818PropofolCytochrome P450 2B6enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-1enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-9enzyme
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-2target
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-3target
DB00818PropofolSerum albumincarrier
DB00818PropofolSodium channel protein type 4 subunit alphatarget
DB00818PropofolSodium channel protein type 2 subunit alphatarget
DB00818PropofolFatty-acid amide hydrolase 1enzyme
DB00818PropofolCytochrome P450 2C9enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-8enzyme
DB00818PropofolCytochrome P450 2E1enzyme
DB00818PropofolCytochrome P450 1B1enzyme
DB00818PropofolCytochrome P450 1A1enzyme
DB00818PropofolCytochrome P450 1A2enzyme
DB00818PropofolCytochrome P450 2C18enzyme
DB00818PropofolCytochrome P450 2C19enzyme
DB00818PropofolCytochrome P450 2C8enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-6enzyme
DB00818PropofolGABA-A receptor (anion channel)target
DB00862VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00862VardenafilCytochrome P450 3A4enzyme
DB00862VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilCytochrome P450 3A5enzyme
DB00871TerbutalineBeta-2 adrenergic receptortarget
DB00871TerbutalineCholinesteraseenzyme
DB00871TerbutalineBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-1 adrenergic receptortarget
DB00915AmantadineD(2) dopamine receptortarget
DB00915AmantadineMatrix protein 2target
DB00915AmantadineAromatic-L-amino-acid decarboxylaseenzyme
DB00915AmantadineAmine oxidase [flavin-containing] Benzyme
DB00915AmantadineSolute carrier family 22 member 2transporter
DB00915AmantadineSolute carrier family 22 member 1transporter
DB00915AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-7target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-4target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-3target
DB00916MetronidazoleIron hydrogenase 1target
DB00916MetronidazoleDNAtarget
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleLanosterol 14-alpha demethylasetarget
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineCytochrome P450 2C19enzyme
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00934MaprotilineHistamine H1 receptortarget
DB00934MaprotilineSodium-dependent noradrenaline transportertarget
DB00934MaprotilineAlpha-1 adrenergic receptorstarget
DB00934MaprotilineCytochrome P450 2D6enzyme
DB00934MaprotilineAlpha-1-acid glycoprotein 1carrier
DB00934MaprotilineMuscarinic acetylcholine receptor M1target
DB00934MaprotilineMuscarinic acetylcholine receptor M2target
DB00934MaprotilineMuscarinic acetylcholine receptor M3target
DB00934MaprotilineMuscarinic acetylcholine receptor M4target
DB00934MaprotilineMuscarinic acetylcholine receptor M5target
DB00934MaprotilineCytochrome P450 1A2enzyme
DB00934Maprotiline5-hydroxytryptamine receptor 2Atarget
DB00934Maprotiline5-hydroxytryptamine receptor 2Ctarget
DB00934Maprotiline5-hydroxytryptamine receptor 7target
DB00934MaprotilineD(2) dopamine receptortarget
DB00934MaprotilineAlpha-2 adrenergic receptorstarget
DB00938SalmeterolBeta-2 adrenergic receptortarget
DB00938SalmeterolCytochrome P450 3A4enzyme
DB00938SalmeterolCytochrome P450 2C8enzyme
DB00938SalmeterolCytochrome P450 3A5enzyme
DB00938SalmeterolCytochrome P450 3A7enzyme
DB00938SalmeterolBeta-1 adrenergic receptortarget
DB00938SalmeterolBeta-3 adrenergic receptortarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00949FelbamateCytochrome P450 2C9enzyme
DB00983FormoterolBeta-2 adrenergic receptortarget
DB00983FormoterolCytochrome P450 2C19enzyme
DB00983FormoterolCytochrome P450 2C9enzyme
DB00983FormoterolCytochrome P450 2D6enzyme
DB00983FormoterolCytochrome P450 2A6enzyme
DB00983FormoterolBeta-1 adrenergic receptortarget
DB00983FormoterolBeta-3 adrenergic receptortarget
DB01001SalbutamolBeta-2 adrenergic receptortarget
DB01001SalbutamolBeta-1 adrenergic receptortarget
DB01001SalbutamolCytochrome P450 3A4enzyme
DB01001SalbutamolBeta-3 adrenergic receptortarget
DB01015SulfamethoxazoleBifunctional protein FolCtarget
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01015SulfamethoxazoleBile salt export pumptransporter
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleCytochrome P450 3A7enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleMultidrug resistance protein 1transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1A2transporter
DB01026KetoconazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 26A1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylaseenzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026Ketoconazole17-hydroxylasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026Ketoconazole11-hydroxylasetarget
DB01026KetoconazoleCytochrome P450 19A1target
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01036TolterodineMuscarinic acetylcholine receptor M1target
DB01036TolterodineMuscarinic acetylcholine receptor M2target
DB01036TolterodineMuscarinic acetylcholine receptor M3target
DB01036TolterodineCytochrome P450 2D6enzyme
DB01036TolterodineCytochrome P450 3A4enzyme
DB01036TolterodineCytochrome P450 2C9enzyme
DB01036TolterodineCytochrome P450 2C19enzyme
DB01036TolterodineMuscarinic acetylcholine receptor M4target
DB01036TolterodineMuscarinic acetylcholine receptor M5target
DB01059NorfloxacinDNA gyrase subunit Atarget
DB01059NorfloxacinDNA topoisomerase 4 subunit Atarget
DB01059NorfloxacinDNA topoisomerase 2-alphatarget
DB01059NorfloxacinCytochrome P450 1A2enzyme
DB01059NorfloxacinCytochrome P450 3A4enzyme
DB01059NorfloxacinCytochrome P450 3A5enzyme
DB01059NorfloxacinCytochrome P450 3A7enzyme
DB01059NorfloxacinSolute carrier family 22 member 5transporter
DB01059NorfloxacinSolute carrier family 22 member 6transporter
DB01059NorfloxacinCytochrome P450 1A1enzyme
DB01059NorfloxacinCytochrome P450 2A6enzyme
DB01069PromethazineD(2) dopamine receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineAlpha-1A adrenergic receptortarget
DB01069Promethazine5-hydroxytryptamine receptor 2Atarget
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineMultidrug resistance protein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01072AtazanavirHuman immunodeficiency virus type 1 proteasetarget
DB01072AtazanavirCytochrome P450 3A4enzyme
DB01072AtazanavirCytochrome P450 2C9enzyme
DB01072AtazanavirMultidrug resistance protein 1transporter
DB01072AtazanavirMultidrug resistance-associated protein 1transporter
DB01072AtazanavirCytochrome P450 1A2enzyme
DB01072AtazanavirSerum albumincarrier
DB01072AtazanavirUDP-glucuronosyltransferase 1-1enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 1B1transporter
DB01072AtazanavirSolute carrier organic anion transporter family member 1B3transporter
DB01072AtazanavirCytochrome P450 2C8enzyme
DB01072AtazanavirBile salt export pumptransporter
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 1A2enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineCytochrome P450 2C18enzyme
DB01075DiphenhydramineCytochrome P450 2B6enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 1transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01104SertralineSodium-dependent serotonin transportertarget
DB01104SertralineCytochrome P450 2B6enzyme
DB01104SertralineCytochrome P450 2C19enzyme
DB01104SertralineCytochrome P450 2C9enzyme
DB01104SertralineCytochrome P450 2D6enzyme
DB01104SertralineSodium-dependent dopamine transportertarget
DB01104SertralineCYP2B proteinenzyme
DB01104SertralineCytochrome P450 3A4enzyme
DB01104SertralineAmine oxidase [flavin-containing] Benzyme
DB01104SertralineAmine oxidase [flavin-containing] Aenzyme
DB01104SertralineMultidrug resistance protein 1transporter
DB01104SertralineCytochrome P450 1A2enzyme
DB01104SertralineSerum albumincarrier
DB01104SertralineSigma receptortarget
DB01142DoxepinSodium-dependent serotonin transportertarget
DB01142DoxepinSodium-dependent noradrenaline transportertarget
DB01142DoxepinHistamine H1 receptortarget
DB01142DoxepinHistamine H2 receptortarget
DB01142DoxepinCytochrome P450 2D6enzyme
DB01142DoxepinMuscarinic acetylcholine receptor M1target
DB01142DoxepinMuscarinic acetylcholine receptor M2target
DB01142DoxepinMuscarinic acetylcholine receptor M3target
DB01142DoxepinMuscarinic acetylcholine receptor M4target
DB01142DoxepinMuscarinic acetylcholine receptor M5target
DB01142DoxepinAlpha-1A adrenergic receptortarget
DB01142Doxepin5-hydroxytryptamine receptor 1Atarget
DB01142Doxepin5-hydroxytryptamine receptor 2Atarget
DB01142DoxepinD(2) dopamine receptortarget
DB01142DoxepinCytochrome P450 2C19enzyme
DB01142DoxepinCytochrome P450 2C9enzyme
DB01142DoxepinCytochrome P450 1A2enzyme
DB01142DoxepinAlpha-1-acid glycoprotein 1carrier
DB01142DoxepinMultidrug resistance protein 1transporter
DB01142Doxepin5-hydroxytryptamine receptor 2Btarget
DB01142Doxepin5-hydroxytryptamine receptor 2Ctarget
DB01142DoxepinAlpha-1B adrenergic receptortarget
DB01142DoxepinAlpha-1D adrenergic receptortarget
DB01142DoxepinAlpha-2A adrenergic receptortarget
DB01142DoxepinAlpha-2B adrenergic receptortarget
DB01142DoxepinAlpha-2C adrenergic receptortarget
DB01142DoxepinCytochrome P450 3A4enzyme
DB01142Doxepin5-hydroxytryptamine receptor 6target
DB01142DoxepinHistamine H4 receptortarget
DB01142DoxepinPotassium voltage-gated channel subfamily H member 2target
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineMultidrug resistance protein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2A6enzyme
DB01151DesipramineCytochrome P450 2C18enzyme
DB01151DesipramineCytochrome P450 2C19enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineD(2) dopamine receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 2D6enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleMultidrug resistance protein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01189DesfluraneCalcium-transporting ATPase type 2C member 1target
DB01189DesfluraneNADH-ubiquinone oxidoreductase chain 1target
DB01189DesfluraneGlycine receptor subunit alpha-1target
DB01189DesfluraneGlutamate receptor 1target
DB01189DesfluraneGABA-A receptor (anion channel)target
DB01189DesfluranePotassium voltage-gated channel subfamily A member 1target
DB01189DesfluraneATP synthase subunit delta, mitochondrialtarget
DB01189DesfluraneSerum albumincarrier
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideD(2) dopamine receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233MetoclopramideCytochrome P450 11B1, mitochondrialenzyme
DB01233MetoclopramideCytochrome P450 11B2, mitochondrialenzyme
DB01233MetoclopramideSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01233MetoclopramideAcetylcholinesterasetarget
DB01236SevofluraneCalcium-transporting ATPase type 2C member 1target
DB01236SevofluraneNADH-ubiquinone oxidoreductase chain 1target
DB01236SevofluraneGlycine receptor subunit alpha-1target
DB01236SevofluraneGlutamate receptor 1target
DB01236SevofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB01236SevofluranePotassium voltage-gated channel subfamily A member 1target
DB01236SevofluraneATP synthase subunit delta, mitochondrialtarget
DB01236SevofluraneCytochrome P450 2E1enzyme
DB01236SevofluraneSerum albumincarrier
DB01236SevofluraneCytochrome P450 2A6enzyme
DB01236SevofluraneCytochrome P450 2B6enzyme
DB01236SevofluraneCytochrome P450 3A4enzyme
DB01236SevofluraneGABA-A receptor (anion channel)target
DB01238AripiprazoleD(2) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Atarget
DB01238AripiprazoleCytochrome P450 3A4enzyme
DB01238AripiprazoleCytochrome P450 2D6enzyme
DB01238Aripiprazole5-hydroxytryptamine receptor 1Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Dtarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Etarget
DB01238AripiprazoleD(1A) dopamine receptortarget
DB01238AripiprazoleD(1B) dopamine receptortarget
DB01238AripiprazoleD(3) dopamine receptortarget
DB01238AripiprazoleD(4) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Ctarget
DB01238Aripiprazole5-hydroxytryptamine receptor 3Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 6target
DB01238Aripiprazole5-hydroxytryptamine receptor 7target
DB01238AripiprazoleHistamine H1 receptortarget
DB01238AripiprazoleAlpha-1A adrenergic receptortarget
DB01238AripiprazoleAlpha-1B adrenergic receptortarget
DB01238AripiprazoleAlpha-2A adrenergic receptortarget
DB01238AripiprazoleAlpha-2B adrenergic receptortarget
DB01238AripiprazoleAlpha-2C adrenergic receptortarget
DB01238AripiprazoleMuscarinic acetylcholine receptor M1target
DB01238AripiprazoleMuscarinic acetylcholine receptor M2target
DB01238AripiprazoleMuscarinic acetylcholine receptor M3target
DB01238AripiprazoleMuscarinic acetylcholine receptor M4target
DB01238AripiprazoleMuscarinic acetylcholine receptor M5target
DB01238AripiprazoleCytochrome P450 3A5enzyme
DB01238AripiprazoleCytochrome P450 3A7enzyme
DB01254DasatinibTyrosine-protein kinase ABL1target
DB01254DasatinibAbelson tyrosine-protein kinase 2target
DB01254DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DB01254DasatinibTyrosine-protein kinase Fyntarget
DB01254DasatinibTyrosine-protein kinase Lcktarget
DB01254DasatinibTyrosine-protein kinase Yestarget
DB01254DasatinibMast/stem cell growth factor receptor Kittarget
DB01254DasatinibPlatelet-derived growth factor receptor betatarget
DB01254DasatinibEphrin type-A receptor 2target
DB01254DasatinibSignal transducer and activator of transcription 5Btarget
DB01254DasatinibCytochrome P450 3A4enzyme
DB01254DasatinibMultidrug resistance protein 1transporter
DB01254DasatinibATP-binding cassette sub-family G member 2transporter
DB01254DasatinibCytochrome P450 1A1enzyme
DB01254DasatinibCytochrome P450 1A2enzyme
DB01254DasatinibCytochrome P450 1B1enzyme
DB01254DasatinibCytochrome P450 3A5enzyme
DB01254DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01254DasatinibTyrosine-protein kinase BTKtarget
DB01254DasatinibNuclear receptor subfamily 4 group A member 3target
DB01254DasatinibBreakpoint cluster region proteintarget
DB01254DasatinibTyrosine-protein kinase CSKtarget
DB01254DasatinibEphrin type-A receptor 5target
DB01254DasatinibEphrin type-B receptor 4target
DB01254DasatinibTyrosine-protein kinase Fgrtarget
DB01254DasatinibTyrosine-protein kinase FRKtarget
DB01254DasatinibHeat shock cognate 71 kDa proteintarget
DB01254DasatinibTyrosine-protein kinase Lyntarget
DB01254DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DB01254DasatinibMitogen-activated protein kinase 14target
DB01254DasatinibAmidophosphoribosyltransferasetarget
DB01259LapatinibEpidermal growth factor receptortarget
DB01259LapatinibReceptor tyrosine-protein kinase erbB-2target
DB01259LapatinibCytochrome P450 3A4enzyme
DB01259LapatinibCytochrome P450 2C8enzyme
DB01259LapatinibMultidrug resistance protein 1transporter
DB01259LapatinibAntigen peptide transporter 1transporter
DB01259LapatinibCytochrome P450 3A5enzyme
DB01259LapatinibCytochrome P450 2C19enzyme
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleMultidrug resistance protein 1transporter
DB01263PosaconazoleLanosterol 14-alpha demethylasetarget
DB01268SunitinibPlatelet-derived growth factor receptor betatarget
DB01268SunitinibVascular endothelial growth factor receptor 1target
DB01268SunitinibVascular endothelial growth factor receptor 2target
DB01268SunitinibVascular endothelial growth factor receptor 3target
DB01268SunitinibMast/stem cell growth factor receptor Kittarget
DB01268SunitinibReceptor-type tyrosine-protein kinase FLT3target
DB01268SunitinibMacrophage colony-stimulating factor 1 receptortarget
DB01268SunitinibPlatelet-derived growth factor receptor alphatarget
DB01268SunitinibCytochrome P450 3A4enzyme
DB01268SunitinibCytochrome P450 3A5enzyme
DB01268SunitinibCytochrome P450 3A7enzyme
DB01268SunitinibMultidrug resistance-associated protein 4transporter
DB01268SunitinibMultidrug resistance protein 1transporter
DB01268SunitinibCanalicular multispecific organic anion transporter 1transporter
DB01268SunitinibATP-binding cassette sub-family G member 2transporter
DB01274ArformoterolBeta-2 adrenergic receptortarget
DB01274ArformoterolCytochrome P450 2D6enzyme
DB01274ArformoterolCytochrome P450 2C19enzyme
DB01274ArformoterolCytochrome P450 2A6enzyme
DB01274ArformoterolCytochrome P450 2C9enzyme
DB01403MethotrimeprazineD(3) dopamine receptortarget
DB01403MethotrimeprazineHistamine H1 receptortarget
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M1target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M2target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M3target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M4target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M5target
DB01403MethotrimeprazineAlpha-1A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1D adrenergic receptortarget
DB01403MethotrimeprazineCytochrome P450 2D6enzyme
DB01403MethotrimeprazineD(2) dopamine receptortarget
DB01403MethotrimeprazineD(1A) dopamine receptortarget
DB01403MethotrimeprazineD(1B) dopamine receptortarget
DB01403MethotrimeprazineD(4) dopamine receptortarget
DB01403MethotrimeprazineAlpha-2A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2C adrenergic receptortarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
DB01403MethotrimeprazineCytochrome P450 2E1enzyme
DB01403MethotrimeprazineCytochrome P450 1A2enzyme
DB01591SolifenacinMuscarinic acetylcholine receptor M3target
DB01591SolifenacinMuscarinic acetylcholine receptor M1target
DB01591SolifenacinCytochrome P450 3A4enzyme
DB01591SolifenacinMuscarinic acetylcholine receptor M2target
DB01591SolifenacinMuscarinic acetylcholine receptor M4target
DB01591SolifenacinMuscarinic acetylcholine receptor M5target
DB01623ThiothixeneCytochrome P450 1A2enzyme
DB01623ThiothixeneCytochrome P450 2D6enzyme
DB01623ThiothixeneD(2) dopamine receptortarget
DB01623ThiothixeneD(1A) dopamine receptortarget
DB01623Thiothixene5-hydroxytryptamine receptor 2Atarget
DB01623ThiothixeneSolute carrier family 22 member 1transporter
DB01623ThiothixeneSerum albumincarrier
DB02546VorinostatHistone deacetylase 1target
DB02546VorinostatHistone deacetylase 2target
DB02546VorinostatHistone deacetylase 3target
DB02546VorinostatHistone deacetylase 6target
DB02546VorinostatHistone deacetylase 8target
DB02546VorinostatAcetoin utilization proteintarget
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 2target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 3target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 4target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 5target
DB04953EzogabineUDP-glucuronosyltransferase 1-1enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-3enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-4enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-9enzyme
DB04953EzogabineCytochrome P450 2A6enzyme
DB04953EzogabineArylamine N-acetyltransferase 2enzyme
DB05039IndacaterolBeta-2 adrenergic receptortarget
DB05039IndacaterolCytochrome P450 3A4enzyme
DB05039IndacaterolUDP-glucuronosyltransferase 1-1enzyme
DB05039IndacaterolMultidrug resistance protein 1transporter
DB06663PasireotideSomatostatin receptor type 1target
DB06663PasireotideSomatostatin receptor type 2target
DB06663PasireotideSomatostatin receptor type 3target
DB06663PasireotideSomatostatin receptor type 5target
DB06663PasireotideCytochrome P450 3A4enzyme
DB06699DegarelixGonadotropin-releasing hormone receptortarget
DB06719BuserelinLutropin-choriogonadotropic hormone receptortarget
DB06719BuserelinGonadotropin-releasing hormone receptortarget
DB06719BuserelinCytochrome P450 19A1enzyme
DB06788HistrelinGonadotropin-releasing hormone receptortarget
DB06825TriptorelinGonadotropin-releasing hormone receptortarget
DB08864RilpivirineCytochrome P450 3A4enzyme
DB08864RilpivirineReverse transcriptase/RNaseHtarget
DB08864RilpivirineNuclear receptor subfamily 1 group I member 2target
DB08864RilpivirineCytochrome P450 2C19enzyme
DB08864RilpivirineCytochrome P450 2B6enzyme
DB08864RilpivirineCytochrome P450 1A2enzyme
DB08864RilpivirineMultidrug resistance protein 1transporter
DB08864RilpivirineATP-binding cassette sub-family G member 2transporter
DB08864RilpivirineSolute carrier organic anion transporter family member 1B1transporter
DB08864RilpivirineSolute carrier organic anion transporter family member 1B3transporter
DB08864RilpivirineSerum albumincarrier
DB08864RilpivirineCytochrome P450 2D6enzyme
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2D6enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodCytochrome P450 4F12enzyme
DB08868FingolimodHistone deacetylase 1target
DB08871EribulinApoptosis regulator Bcl-2target
DB08871EribulinTubulin beta-1 chaintarget
DB08893MirabegronCytochrome P450 3A4enzyme
DB08893MirabegronCytochrome P450 2D6enzyme
DB08893MirabegronMultidrug resistance protein 1transporter
DB08893MirabegronSolute carrier organic anion transporter family member 1A2transporter
DB08893MirabegronSerum albumincarrier
DB08893MirabegronAlpha-1-acid glycoprotein 1carrier
DB08893MirabegronCholinesteraseenzyme
DB08893MirabegronBeta-3 adrenergic receptortarget
DB08912DabrafenibCytochrome P450 3A4enzyme
DB08912DabrafenibCytochrome P450 2C8enzyme
DB08912DabrafenibMultidrug resistance protein 1transporter
DB08912DabrafenibATP-binding cassette sub-family G member 2transporter
DB08912DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DB08912DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DB08912DabrafenibSolute carrier family 22 member 6transporter
DB08912DabrafenibSolute carrier family 22 member 8transporter
DB08912DabrafenibSerine/threonine-protein kinase B-raftarget
DB08912DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB08912DabrafenibSerine/threonine-protein kinase SIK1target
DB08912DabrafenibSerine/threonine-protein kinase Nek11target
DB08912DabrafenibLIM domain kinase 1target
DB09080OlodaterolBeta-2 adrenergic receptortarget
DB09080OlodaterolCytochrome P450 2C9enzyme
DB09080OlodaterolCytochrome P450 2C8enzyme
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB01071MequitazineHistamine H1 receptortarget
DB01071MequitazineCytochrome P450 2D6enzyme
DB01071MequitazineCytochrome P450 3A4enzyme
DB00613AmodiaquineHistamine N-methyltransferasetarget
DB00613AmodiaquineCytochrome P450 2C8enzyme
DB00613AmodiaquineCytochrome P450 2D6enzyme
DB00613AmodiaquineFe(II)-protoporphyrin IXtarget
DB00613AmodiaquineCytochrome P450 1A1enzyme
DB00613AmodiaquineCytochrome P450 1B1enzyme
DB00613AmodiaquineCytochrome P450 2C9enzyme
DB00613AmodiaquineMultidrug resistance protein 1transporter
DB05465TandutinibReceptor-type tyrosine-protein kinase FLT3target
DB05465TandutinibPlatelet-derived growth factor Dtarget
DB00467EnoxacinDNA gyrase subunit Atarget
DB00467EnoxacinDNA topoisomerase 4 subunit Atarget
DB00467EnoxacinDNA topoisomerase 2-alphatarget
DB00467EnoxacinCytochrome P450 1A2enzyme
DB04576FleroxacinDNA topoisomerase 2-alphatarget
DB04576FleroxacinDNA gyrase subunit Atarget
DB04576FleroxacinDNA topoisomerase 4 subunit Atarget
DB04576FleroxacinCytochrome P450 1A2enzyme
DB08972FlumequineCytochrome P450 1A2enzyme
DB11774PazufloxacinCytochrome P450 1A2enzyme
DB00487PefloxacinDNA gyrase subunit Atarget
DB00487PefloxacinDNA topoisomerase 4 subunit Atarget
DB00487PefloxacinDNA topoisomerase 2-alphatarget
DB00487PefloxacinCytochrome P450 1A2enzyme
DB00487PefloxacinDNA topoisomerase 1target
DB11892PrulifloxacinCytochrome P450 1A2enzyme
DB00817RosoxacinDNA topoisomerase 4 subunit Atarget
DB00817RosoxacinDNA gyrase subunit Btarget
DB00817RosoxacinCytochrome P450 1A2enzyme
DB13772RufloxacinCytochrome P450 1A2enzyme
DB11491SarafloxacinCytochrome P450 1A2enzyme
DB01166CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01166CilostazolCytochrome P450 2C19enzyme
DB01166CilostazolCytochrome P450 3A4enzyme
DB01166CilostazolCytochrome P450 3A5enzyme
DB01166CilostazolCytochrome P450 3A7enzyme
DB01166CilostazolCytochrome P450 1A2enzyme
DB01166CilostazolCytochrome P450 2D6enzyme
DB00843DonepezilAcetylcholinesterasetarget
DB00843Donepezil5-hydroxytryptamine receptor 2Atarget
DB00843DonepezilCytochrome P450 3A4enzyme
DB00843DonepezilCytochrome P450 2D6enzyme
DB00843DonepezilCytochrome P450 2C9enzyme
DB01044GatifloxacinSerum albumincarrier
DB01044GatifloxacinDNA gyrase subunit Atarget
DB01044GatifloxacinDNA gyrase subunit Btarget
DB01044GatifloxacinDNA topoisomerase 4 subunit Atarget
DB01044GatifloxacinDNA topoisomerase 4 subunit Btarget
DB01044GatifloxacinCytochrome P450 1A2enzyme
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineMultidrug resistance protein 1transporter
DB09488AcrivastineHistamine H1 receptortarget
DB06766AlcaftadineHistamine H1 receptortarget
DB01246AlimemazineHistamine H1 receptortarget
DB01246AlimemazineCytochrome P450 3A4enzyme
DB14185Aripiprazole lauroxilD(2) dopamine receptortarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Atarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 2Atarget
DB14185Aripiprazole lauroxilCytochrome P450 3A4enzyme
DB14185Aripiprazole lauroxilCytochrome P450 2D6enzyme
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Btarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Dtarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Etarget
DB14185Aripiprazole lauroxilD(1A) dopamine receptortarget
DB14185Aripiprazole lauroxilD(1B) dopamine receptortarget
DB14185Aripiprazole lauroxilD(3) dopamine receptortarget
DB14185Aripiprazole lauroxilD(4) dopamine receptortarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 2Ctarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 3Atarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 6target
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 7target
DB14185Aripiprazole lauroxilHistamine H1 receptortarget
DB14185Aripiprazole lauroxilAlpha-1A adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-1B adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2A adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2B adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2C adrenergic receptortarget
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M1target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M2target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M3target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M4target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M5target
DB14185Aripiprazole lauroxilCytochrome P450 3A5enzyme
DB14185Aripiprazole lauroxilCytochrome P450 3A7enzyme
DB14185Aripiprazole lauroxilSerum albumincarrier
DB00719AzatadineHistamine H1 receptortarget
DB00719AzatadineCytochrome P450 3A4enzyme
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineMultidrug resistance protein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2B6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00245BenzatropineMuscarinic acetylcholine receptor M1target
DB00245BenzatropineSodium-dependent dopamine transportertarget
DB00245BenzatropineHistamine H1 receptortarget
DB00245BenzatropineCytochrome P450 2C19enzyme
DB00245BenzatropineCytochrome P450 2D6enzyme
DB11591BilastineHistamine H1 receptortarget
DB11591BilastineATP-binding cassette sub-family B member 5transporter
DB11591BilastineSolute carrier organic anion transporter family member 1A2transporter
DB11591BilastineSolute carrier organic anion transporter family member 2B1transporter
DB11591BilastineSolute carrier family 22 member 1transporter
DB00354BuclizineHistamine H1 receptortarget
DB00354BuclizineMuscarinic acetylcholine receptor M1target
DB00341CetirizineHistamine H1 receptortarget
DB08936ChlorcyclizineHistamine H1 receptortarget
DB01239ChlorprothixeneD(1A) dopamine receptortarget
DB01239ChlorprothixeneD(2) dopamine receptortarget
DB01239ChlorprothixeneD(3) dopamine receptortarget
DB01239Chlorprothixene5-hydroxytryptamine receptor 2Atarget
DB01239Chlorprothixene5-hydroxytryptamine receptor 2Btarget
DB01239Chlorprothixene5-hydroxytryptamine receptor 2Ctarget
DB01239ChlorprothixeneHistamine H1 receptortarget
DB01239ChlorprothixeneMuscarinic acetylcholine receptor M1target
DB01239ChlorprothixeneMuscarinic acetylcholine receptor M2target
DB01239ChlorprothixeneMuscarinic acetylcholine receptor M3target
DB01239ChlorprothixeneMuscarinic acetylcholine receptor M4target
DB01239ChlorprothixeneMuscarinic acetylcholine receptor M5target
DB01239ChlorprothixeneMultidrug resistance protein 1transporter
DB01176CyclizineHistamine H1 receptortarget
DB01176CyclizineEstrogen sulfotransferasetarget
DB01176CyclizineCytochrome P450 2C9enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00405DexbrompheniramineHistamine H1 receptortarget
DB09167Dosulepin5-hydroxytryptamine receptor 1Atarget
DB09167Dosulepin5-hydroxytryptamine receptor 2Atarget
DB09167DosulepinCytochrome P450 2D6enzyme
DB09167DosulepinCytochrome P450 1A2enzyme
DB09167DosulepinCytochrome P450 2C19enzyme
DB09167DosulepinCytochrome P450 2C9enzyme
DB09167DosulepinHistamine H1 receptortarget
DB09167DosulepinMuscarinic acetylcholine receptor M1target
DB09167DosulepinMuscarinic acetylcholine receptor M2target
DB09167DosulepinMuscarinic acetylcholine receptor M3target
DB09167DosulepinMuscarinic acetylcholine receptor M4target
DB09167DosulepinMuscarinic acetylcholine receptor M5target
DB09167DosulepinSodium-dependent noradrenaline transportertarget
DB09167DosulepinSodium-dependent serotonin transportertarget
DB09167DosulepinAlpha-1 adrenergic receptorstarget
DB09167DosulepinAlpha-2 adrenergic receptorstarget
DB00366DoxylamineHistamine H1 receptortarget
DB00366DoxylamineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineCYP2B proteinenzyme
DB00366DoxylamineNuclear receptor subfamily 1 group I member 3target
DB11742EbastineCytochrome P450 3A4enzyme
DB00751EpinastineHistamine H1 receptortarget
DB00751EpinastineHistamine H2 receptortarget
DB00751EpinastineAlpha-1A adrenergic receptortarget
DB00751EpinastineAlpha-2A adrenergic receptortarget
DB00751Epinastine5-hydroxytryptamine receptor 2Atarget
DB00751Epinastine5-hydroxytryptamine receptor 7target
DB00751EpinastineMultidrug resistance protein 1transporter
DB00751EpinastineCytochrome P450 2B6enzyme
DB00751EpinastineCytochrome P450 2D6enzyme
DB00751EpinastineCytochrome P450 3A4enzyme
DB00920KetotifenHistamine H1 receptortarget
DB00920Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB01106LevocabastineNeurotensin receptor type 2target
DB01106LevocabastineHistamine H1 receptortarget
DB06282LevocetirizineHistamine H1 receptortarget
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB00768OlopatadineHistamine H1 receptortarget
DB00768OlopatadineProtein S100-A1target
DB00768OlopatadineProtein S100-A12target
DB00768OlopatadineProtein S100-Btarget
DB00768OlopatadineProtein S100-A13target
DB00768OlopatadineProtein S100-A2target
DB00768OlopatadineCytochrome P450 3A4enzyme
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB11614RupatadineCytochrome P450 3A4enzyme
DB11614RupatadineCytochrome P450 2C9enzyme
DB11614RupatadineCytochrome P450 2C19enzyme
DB11614RupatadineCytochrome P450 2D6enzyme
DB11614RupatadinePlatelet-activating factor receptortarget
DB11614RupatadineHistamine H1 receptortarget
DB00427TriprolidineHistamine H1 receptortarget
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB00835BrompheniramineCytochrome P450 2B6enzyme
DB00835BrompheniramineCytochrome P450 2C19enzyme
DB00835BrompheniramineCytochrome P450 2C8enzyme
DB00835BrompheniramineCytochrome P450 2C9enzyme
DB00835BrompheniramineCytochrome P450 2D6enzyme
DB00835BrompheniramineCytochrome P450 2E1enzyme
DB00835BrompheniramineCytochrome P450 3A4enzyme
DB01426AjmalineCytochrome P450 2D6enzyme
DB01426AjmalineAlpha-1-acid glycoprotein 1carrier
DB01426AjmalineSodium channel protein type 5 subunit alphatarget
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00381AmlodipineVoltage-gated calcium channel beta 1 subunit splice variant CavB1dtarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineCytochrome P450 3A7enzyme
DB00381AmlodipineCytochrome P450 1A2enzyme
DB00381AmlodipineMultidrug resistance protein 1transporter
DB00381AmlodipineCytochrome P450 2A6enzyme
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2C9enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB11785AnisodamineCytochrome P450 2D6enzyme
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB09229AranidipineAlpha adrenergic receptortarget
DB09229AranidipineSerum albumincarrier
DB09229AranidipineAlpha-1-acid glycoprotein 1carrier
DB09229AranidipineCytochrome P450 3A4enzyme
DB13488BencyclaneCytochrome P450 3A4enzyme
DB01158BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
DB08808BupranololBeta-1 adrenergic receptortarget
DB08808BupranololBeta-2 adrenergic receptortarget
DB08808BupranololBeta-3 adrenergic receptortarget
DB08808BupranololCytochrome P450 2D6enzyme
DB06468CariporideSodium/hydrogen exchanger 1target
DB06468CariporideMyeloperoxidaseenzyme
DB00521CarteololBeta-2 adrenergic receptortarget
DB00521CarteololBeta-1 adrenergic receptortarget
DB00521CarteololCytochrome P450 2D6enzyme
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget
DB04846CeliprololCytochrome P450 2D6enzyme
DB00390DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00390DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00390DigoxinMultidrug resistance protein 1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 4C1transporter
DB00390DigoxinSolute carrier family 22 member 8transporter
DB00390DigoxinSolute carrier organic anion transporter family member 2B1transporter
DB00390DigoxinBile salt export pumptransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1A2transporter
DB00390DigoxinOrganic solute transporter subunit alphatransporter
DB00390DigoxinOrganic solute transporter subunit betatransporter
DB00390DigoxinSolute carrier organic anion transporter family member 4A1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B3transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1C1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B1transporter
DB00390DigoxinCytochrome P450 3A4enzyme
DB01396DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB01396DigitoxinSerum albumincarrier
DB01396DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01396DigitoxinCytochrome P450 3A4enzyme
DB01396DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DB01396DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DB01396DigitoxinMultidrug resistance protein 1transporter
DB00661VerapamilSodium channel protein type 5 subunit alphatarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-4target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-3target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-2target
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilCytochrome P450 3A7enzyme
DB00661VerapamilMultidrug resistance protein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 1transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilATP-binding cassette sub-family G member 2transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2C18enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00661VerapamilBile salt export pumptransporter
DB09235EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09235EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09235EfonidipineCytochrome P450 3A4enzyme
DB01228EncainideSodium channel protein type 5 subunit alphatarget
DB01228EncainideCytochrome P450 2D6enzyme
DB00187EsmololBeta-1 adrenergic receptortarget
DB00187EsmololCytochrome P450 2D6enzyme
DB00593EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00593EthosuximideCytochrome P450 3A4enzyme
DB00593EthosuximideCytochrome P450 2E1enzyme
DB00593EthosuximideCytochrome P450 3A43enzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineMultidrug resistance protein 1transporter
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01023FelodipineBile salt export pumptransporter
DB00996GabapentinAdenosine receptor A1target
DB00996GabapentinVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00996GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
DB00996GabapentinNMDA receptortarget
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 1target
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 2target
DB00996GabapentinCytochrome P450 3A4enzyme
DB12923GallopamilCytochrome P450 3A4enzyme
DB00424HyoscyamineMuscarinic acetylcholine receptor M1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M2target
DB00424HyoscyamineMuscarinic acetylcholine receptor M3target
DB00424HyoscyamineMuscarinic acetylcholine receptor M4target
DB08952IndenololCytochrome P450 2D6enzyme
DB09236LacidipineCytochrome P450 3A4enzyme
DB09236LacidipineSerum albumincarrier
DB09236LacidipineAlpha-1-acid glycoprotein 1carrier
DB09236LacidipineVoltage dependent L type calcium channeltarget
DB00555LamotrigineSodium channel protein type 2 subunit alphatarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-4enzyme
DB00555LamotrigineMultidrug resistance protein 1transporter
DB00555LamotrigineUDP-glucuronosyltransferase 1-3enzyme
DB00555LamotrigineDihydrofolate reductaseenzyme
DB00555Lamotrigine5-hydroxytryptamine receptor 3Atarget
DB00555LamotrigineVoltage-dependent R-type calcium channel subunit alpha-1Etarget
DB00555LamotrigineAdenosine receptor A1target
DB00555LamotrigineAdenosine receptor A2atarget
DB00555LamotrigineAlpha-1A adrenergic receptortarget
DB00555LamotrigineAlpha-2A adrenergic receptortarget
DB00555LamotrigineBeta-1 adrenergic receptortarget
DB00555LamotrigineD(1) dopamine receptortarget
DB00555LamotrigineD(2) dopamine receptortarget
DB00555LamotrigineGABA-A receptor (anion channel)target
DB00555LamotrigineGABA-A receptor (benzodiazepine site)target
DB00555LamotrigineHistamine H1 receptortarget
DB00555LamotrigineKappa-type opioid receptortarget
DB00555LamotrigineMuscarinic acetylcholine receptortarget
DB00555Lamotrigine5-hydroxytryptamine receptor 2Atarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-1enzyme
DB00555LamotrigineCytochrome P450 3A4enzyme
DB01202LevetiracetamSynaptic vesicle glycoprotein 2Atarget
DB01202LevetiracetamMultidrug resistance protein 1transporter
DB01202LevetiracetamCanalicular multispecific organic anion transporter 1transporter
DB01202LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB01202LevetiracetamCytochrome P450 3A4enzyme
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanCytochrome P450 2C8enzyme
DB00678LosartanMultidrug resistance protein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 1A2enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00678LosartanBile salt export pumptransporter
DB00825MentholTransient receptor potential cation channel subfamily A member 1target
DB00825MentholTransient receptor potential cation channel subfamily M member 8target
DB00825MentholTransient receptor potential cation channel subfamily V member 3target
DB00825MentholKappa-type opioid receptortarget
DB00825MentholVoltage dependent L type calcium channeltarget
DB00825MentholCytochrome P450 3A4enzyme
DB05246MethsuximideCytochrome P450 2C19enzyme
DB05246MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00680MoricizineSodium channel protein type 5 subunit alphatarget
DB09239NiguldipineAlpha-1A adrenergic receptortarget
DB09239NiguldipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineMultidrug resistance protein 1transporter
DB01054NitrendipineBile salt export pumptransporter
DB01074PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
DB01074PerhexilineCytochrome P450 2D6enzyme
DB01074PerhexilineCytochrome P450 2B6enzyme
DB01074PerhexilineCytochrome P450 3A4enzyme
DB01074PerhexilinePotassium voltage-gated channel subfamily H member 2target
DB12712PilsicainideBile salt export pumptransporter
DB09090PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB09090PinaveriumCytochrome P450 3A4enzyme
DB00230PregabalinVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00230PregabalinExcitatory amino acid transporter 3transporter
DB00230PregabalinCytochrome P450 3A4enzyme
DB11770TalinololCytochrome P450 2D6enzyme
DB12093TetrahydropalmatineD(1A) dopamine receptortarget
DB12093TetrahydropalmatineD(2) dopamine receptortarget
DB12093TetrahydropalmatineCytochrome P450 3A4enzyme
DB00373TimololBeta-1 adrenergic receptortarget
DB00373TimololBeta-2 adrenergic receptortarget
DB00373TimololCytochrome P450 2D6enzyme
DB00373TimololMultidrug resistance protein 1transporter
DB00373TimololCytochrome P450 2C19enzyme
DB00373TimololLysozymetarget
DB09089TrimebutineMu-type opioid receptortarget
DB09089TrimebutineVoltage dependent L type calcium channeltarget
DB09089TrimebutineCalcium-activated potassium channeltarget
DB09089TrimebutineVoltage-dependent T-type calcium channeltarget
DB09089TrimebutineMuscarinic acetylcholine receptor M1target
DB09089TrimebutineMuscarinic acetylcholine receptor M2target
DB09089TrimebutineMuscarinic acetylcholine receptor M3target
DB09089TrimebutineMuscarinic acetylcholine receptor M4target
DB09089TrimebutineCytochrome P450 3A4enzyme
DB00347TrimethadioneVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00347TrimethadioneCytochrome P450 2C19enzyme
DB00347TrimethadioneCytochrome P450 2C8enzyme
DB00347TrimethadioneCytochrome P450 2C9enzyme
DB00347TrimethadioneCytochrome P450 2E1enzyme
DB00347TrimethadioneCytochrome P450 3A4enzyme
DB06217VernakalantCytochrome P450 2D6enzyme
DB06217VernakalantSodium channel protein type 5 subunit alphatarget
DB06217VernakalantPotassium voltage-gated channel subfamily A member 5target
DB06217VernakalantPotassium voltage-gated channel subfamily D member 3target
DB06217VernakalantPotassium voltage-gated channel subfamily H member 2target
DB06283ZiconotideCytochrome P450 3A4enzyme
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme