Benzene Derivatives

DrugDrug NameDrug Indication
DB00179MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
DB00233Aminosalicylic AcidFor the treatment of tuberculosis
DB00244MesalazineMesalazine is indicated for the induction of remission in patients with active or mild to moderate acute exacerbations of ulcerative colitis and for the maintenance of remission of ulcerative colitis [FDA Label], [L5101]. Prescribing information for mesalazine in the UK also indicates the medication for the maintenance of remission of Crohn's ileo-colitis [L5101].
DB00255DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
DB00258Calcium acetateCalcium acetate is one of a number of calcium salts used to treat hyperphosphatemia (too much phosphate in the blood) in patients with kidney disease.
DB00265CrotamitonFor eradication of scabies (Sarcoptes scabiei) and for symptomatic treatment of pruritic skin.
DB00269ChlorotrianiseneUsed to treat symptoms of menopause, deficiencies in ovary function (including underdevelopment of female sexual characteristics and some types of infertility), and in rare cases, prostate cancer. Chlorotrianisene may also be used to prevent breast engorgement following childbirth.
DB00271DiatrizoateUsed, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography. It can be used for imaging the gastrointestinal tract in patients allergic to barium.
DB00310ChlorthalidoneChlorthalidone is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Chlorthalidone has also been found useful in edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.
DB00323TolcaponeUsed as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies.
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00345Aminohippuric acidUsed to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
DB00348NitisinoneUsed as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1.
DB00379MexiletineFor the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.
DB00391SulpirideSulpiride is indicated for the treatment of schizophrenia.
DB00398SorafenibSorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
DB00409RemoxiprideRemoxipride is an atypical antipsychotic once used for the treatment of schizophrenia.
DB00423MethocarbamolMethocarbamol tablets and intramuscular injections are indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.[Label,L6268] Oral methocarbamol in America may be given up to 1500mg 4 times daily for 2-3 days.[A31312] In Canada, methocarbamol containing oral formulations are sold over the counter for pain associated with muscle spasm.[L6295] However, if these combination formulations include codeine, they are prescription only.[L6295]
DB00446ChloramphenicolUsed in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis.
DB00481RaloxifeneIndicated for the prevention and treatment of osteoporosis in postmenopausal women, as well as prevention and treatment of corticosteroid-induced bone loss.[label] Indicated for the reduction in the risk of invasive breast cancer in postmenopausal women with osteoporosis or postmenopausal women with a high risk for invasive breast cancer.[label]
DB00494EntacaponeUsed as an adjunct to levodopa / carbidopa in the symptomatic treatment of patients with idiopathic Parkinson's Disease who experience the signs and symptoms of end-of-dose "wearing-off".
DB00522BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
DB00539ToremifeneFor the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or receptor-unknown tumors. Toremifene is currently under investigation as a preventative agent for prostate cancer in men with high-grade prostatic intraepithelial neoplasia and no evidence of prostate cancer.
DB00549ZafirlukastFor the prophylaxis and chronic treatment of asthma.
DB00600MonobenzoneUsed topically to treat the loss of skin color (vitiligo).
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00619ImatinibFor the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST).
DB00626BacitracinFor the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. Used against gram positive bacteria. Bacitracin is also used as an inhibitor of proteases and other enzymes. However, specific activity of bactracin's inhibition of protein disulfide isomerase has been called into question.
DB00636ClofibrateFor Primary Dysbetalipoproteinemia (Type III hyperlipidemia) that does not respond adequately to diet. This helps control high cholesterol and high triglyceride levels.
DB00662TrimethobenzamideFor the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
DB00675TamoxifenTamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ.
DB00676Benzyl benzoateUsed to kill lice and the mites responsible for the skin condition scabies.
DB00678LosartanMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00695FurosemideFor the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
DB00712FlurbiprofenFlurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.
DB00721ProcaineUsed as a local anesthetic primarily in oral surgery
DB00737MeclizineFor the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness.
DB00745ModafinilTo improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
DB00756HexachloropheneFor use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
DB00773EtoposideFor use in combination with other chemotherapeutic agents in the treatment of refractory testicular tumors and as first line treatment in patients with small cell lung cancer. Also used to treat other malignancies such as lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme.
DB00784Mefenamic acidFor the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
DB00793HaloproginUsed to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor.
DB00796Candesartan cilexetilMay be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Candesartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
DB00807ProparacaineUsed as a local (ophthalmic) anesthetic.
DB00818PropofolUsed for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
DB00861DiflunisalFor symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.
DB00874GuaifenesinGuaifenesin is an expectorant that is indicated for providing temporary symptomatic relief from congested chests and coughs which may be due to a cold, bronchitis, and/or other breathing illnesses [FDA Label, F4510, L6079].
DB00882ClomifeneUsed mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
DB00887BumetanideFor the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
DB00890DienestrolFor use in the treatment of atrophic vaginitis and kraurosis vulvae.
DB00892OxybuprocaineUsed to temporarily numb the front surface of the eye so that the eye pressure can be measured or a foreign body removed.
DB00895Benzylpenicilloyl PolylysineFor use as a adjunct in assessing the risk of administering penicillin (benzylpenicillin or penicillin G).
DB00936Salicylic acidKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
DB00939Meclofenamic acidFor the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
DB00945Acetylsalicylic acid**Pain, fever, and inflammation** Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. **Other indications** ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. **Important note regarding use of the extended-release formulation [F4405]** In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
DB00950FexofenadineFor management of Seasonal allergic rhinitis
DB00963BromfenacFor the treatment of postoperative inflammation in patients who have undergone cataract extraction.
DB00966TelmisartanUsed alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).
DB00985DimenhydrinateDimenhydrinate is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
DB01014BalsalazideFor the treatment of mildly to moderately active ulcerative colitis.
DB01029IrbesartanFor the treatment of hypertension, as well as diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. Irbesartan is also used as a second line agent in the treatment of congestive heart failure.
DB01035ProcainamideFor the treatment of life-threatening ventricular arrhythmias.
DB01036TolterodineFor the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
DB01039FenofibrateFor use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
DB01075DiphenhydramineDiphenhydramine is a first-generation histamine H1 receptor antagonist (H1 antihistamine) that is widely available as a non-prescription, over-the-counter (OTC) medication. As an OTC medication, diphenhydramine is typically formulated as tablets and creams indicated for use in treating sneezing, runny nose, itchy/watery eyes, itching of nose or throat, insomnia, pruritis, urticaria, insect bites/stings, allergic rashes, and nausea [L5263, L5266, L5269, F3379, A174541]. Additionally, when the use of oral diphenhydramine is impractical, there are also prescription-only formulations such as diphenhydramine injection products that are effective in adults and pediatric patients (other than premature infants and neonates) for: i) the amelioration of allergic reactions to blood or plasma, in anaphylaxis as an adjunct to epinephrine and other standard measures after acute allergic reaction symptoms have been controlled, and for other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated [F3352]; ii) the active treatment of motion sickness [F3352]; and iii) use in parkinsonism when oral therapy is impossible or contraindicated, as follows: parkinsonism in the elderly who are unable to tolerate more potent agents; mild cases of parkinsonism in other age groups, and in other cases of parkinsonism in combination with centrally acting anticholinergic agents [F3352].
DB01086BenzocaineFor general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
DB01091ButenafineFor the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
DB01121PhenacemideUsed to control certain seizures in the treatment of epilepsy.
DB01128BicalutamideFor treatment (together with surgery or LHRH analogue) of advanced prostatic cancer.
DB01161ChloroprocaineFor the production of local anesthesia by infiltration and peripheral nerve block. They are not to be used for lumbar or caudal epidural anesthesia.
DB01168ProcarbazineFor use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.
DB01171MoclobemideFor the treatment of major depressive disorder and bipolar disorder [A31901].
DB01173OrphenadrineIndicated for the treatment of Parkinson's disease.
DB01179PodofiloxFor treatment of external genital warts (Condyloma acuminatum).
DB01187IophendylateIophendylate is used as a contrast agent to locate spinal tumors.
DB01233MetoclopramideFor the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying.
DB01237BromodiphenhydramineFor management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.
DB01241GemfibrozilFor treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.
DB01249IodixanolIodixanol is a contrast agent during coronary angiography.
DB01250OlsalazineFor the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.
DB01294Bismuth subsalicylateUsed to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB01344TolevamerUsed to treat abnormally high potassium levels.
DB01362IohexolIohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
DB01393BezafibrateFor the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus).
DB01397Magnesium salicylateMagnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain
DB01399SalsalateFor relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
DB01401Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DB01428OxybenzoneUsed as an ingredient in sunscreen and other cosmetics.
DB01432CholestyramineIndicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction.
DB01487EmbutramideNot Available
DB01578MetrizamideMetrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column, spinal canal, and central nervous system (CNS) as well as for cisternography by direct injection using standard radiologic techniques to visualize the basal cistern of the brain. For computerized tomography (CT) of the intracranial subarachnoid spaces and for ventriculography by direct injection using standard radiologic techniques to visualize the cerebral ventricles. Also used in pediatric angiocardiography to visualize lesions or malformations of the heart and obstructions or anomalies of the major thoracic vessels. Also used in adult peripheral arteriography to visualize specific regions of the vascular system and blood flow in such areas to help in the diagnosis and evaluation of neoplasms (known or suspected) or vascular diseases (congenital or acquired) that may cause changes in normal vascular anatomy or physiology. Metrizamide is also indicated in adults for intravenous digital arteriography of head and neck.
DB01599ProbucolUsed to lower LDL and HDL cholesterol.
DB01609DeferasiroxFor the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
DB01626PargylineFor the treatment of moderate to severe hypertension.
DB01656RoflumilastRoflumilast is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations. Roflumilast is not a bronchodilator and is not indicated for the relief of acute bronchospasm.
DB01676TrinitrotolueneNot Available
DB01681Benzene Hexacarboxylic AcidNot Available
DB01688P-CresolNot Available
DB017112,3,4,5,6-Pentafluorobenzyl AlcoholNot Available
DB017262-AminophenolNot Available
DB01776M-CresolNot Available
DB01791PiclamilastNot Available
DB01878BenzophenoneNot Available
DB01892HyperforinNot Available
DB019573-ChlorophenolNot Available
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNot Available
DB021053,5-DinitrocatecholNot Available
DB022321,2-DihydroxybenzeneNot Available
DB02266Flufenamic AcidNot Available
DB02362Aminobenzoic acidNot Available
DB024172,4,6-TribromophenolNot Available
DB02464BenzylamineNot Available
DB02513ThymolNot Available
DB025342-AllylphenolNot Available
DB02709ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
DB02715Compound 18Not Available
DB02749Pyromellitic AcidNot Available
DB02795P-Anisic AcidNot Available
DB02822Para-Bromobenzyl AlcoholNot Available
DB028392,4-Dihydroxybenzoic AcidNot Available
DB02877Arotinoid acidNot Available
DB03002p-IodophenolNot Available
DB030582-Aminobenzyl alcoholNot Available
DB030733-MethoxybenzamideNot Available
DB03083IC261Not Available
DB031102-ChlorophenolNot Available
DB03120Para-Toluene SulfonateNot Available
DB03126Mant-AdpNot Available
DB03167PentabromophenolNot Available
DB032434-FluorobenzylamineNot Available
DB03255PhenolPhenol is primarily indicated for minor sore throat pain, sore mouth, minor mouth irritation, and pain associated with canker sores. Additionally, phenol is indicated in the treatment of focal spasticity.
DB034074-NitrocatecholNot Available
DB036443-hydroxyanthranilic acidNot Available
DB03651Picric acidNot Available
DB03728p-Chlorobenzoic acidNot Available
DB03793Benzoic AcidNot Available
DB039463,4-Dihydroxybenzoic AcidNot Available
DB04049CoelenteramideNot Available
DB040523,4-DimethylphenolNot Available
DB04098BalanolNot Available
DB041102-Nitro-P-CresolNot Available
DB04166Anthranilic acidNot Available
DB04200MatairesinolNot Available
DB042144-Nitrophenyl PhosphateNot Available
DB043361-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaNot Available
DB04417P-NitrophenolNot Available
DB04468AfimoxifeneFor the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.
DB04500AcedobenNot Available
DB045282,4-DinitrophenolNot Available
DB045332-Amino-P-CresolNot Available
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB04586o-BromophenolNot Available
DB04711IodipamideIodipamide is used as a contrast agent for cholecystography and intravenous cholangiography.
DB04813BithionolNot Available
DB04824PhenolphthaleinUsed for over a century as a laxative.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB04862MerimepodibFor the treatment of hepatitis C virus (HCV) infection.
DB04863LefradafibanFor the treatment of unstable angina.
DB04884DapoxetineFor the treatment of premature ejaculation.
DB04898XimelagatranFor the treatment of acute deep vein thrombosis.
DB04905TesmilifeneIntended for the treatment of various forms of cancer.
DB04917RenzaprideFor the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
DB04924ItoprideInvestigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous).
DB04938OspemifeneOspemifene is used for the treatment of moderate to dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.
DB04942TamibaroteneInvestigated for use/treatment in leukemia (unspecified).
DB05050ADL5859Investigated for use/treatment in pain (acute or chronic).
DB05073SRT501Investigated for use/treatment in diabetes mellitus type 2 and neurologic disorders.
DB05075TG-100801Investigated for use/treatment in macular degeneration.
DB05130INCB3284Investigated for use/treatment in inflammatory disorders (unspecified).
DB05143OXI-4503Investigated for use/treatment in cancer/tumors (unspecified).
DB05199LX1031Irritable bowel syndrome (IBS) and other gastrointestinal disorders
DB05227APD791For the treatment and prophylaxis of arterial thrombosis.
DB05289TarenflurbilInvestigated for use/treatment in alzheimer's disease and prostate cancer.
DB05377ChlorfensonInvestigated for use/treatment in fungal infections.
DB05399SuccinobucolInvestigated for use/treatment in atherosclerosis, coronary artery disease, diabetes mellitus type 2, and in-stent restenosis.
DB05470VX-702Investigated for use/treatment in coronary artery disease, inflammatory disorders (unspecified), and rheumatoid arthritis.
DB05500AVN-944Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and pancreatic cancer.
DB05507VX-765Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders.
DB05542NaronaprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB05552TG100-115Investigated for use/treatment in angioedema and myocardial infarction.
DB05678SLx-4090Investigated for use/treatment in hyperlipidemia.
DB05683Iodofiltic acid I-123Investigated for use/treatment in cardiac ischemia.
DB05686SivifeneInvestigated for use/treatment in cervical dysplasia/cancer, genital warts, and skin cancer.
DB05708GTS-21Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders.
DB05840AGI-1096Investigated for use/treatment in transplant (rejection).
DB06070SNX-5422Investigated for use/treatment in cancer/tumors (unspecified).
DB06080ABT-869Investigated for use/treatment in leukemia (myeloid), myelodysplastic syndrome, and solid tumors.
DB06083TapinarofInvestigated for use/treatment in psoriasis and psoriatic disorders.
DB06103VX-148Investigated for use/treatment in autoimmune diseases, psoriasis and psoriatic disorders, and viral infection.
DB06134SNS-314Investigated for use/treatment in solid tumors.
DB06188IspinesibInvestigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer.
DB06190SolabegronInvestigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.
DB06197BimosiamoseInvestigated for use/treatment in asthma, psoriasis and psoriatic disorders, atopic dermatitis, inflammatory disorders (unspecified), and chronic obstructive pulmonary disease (COPD).
DB06204TapentadolThe immediate-release formulation of tapentadol is indicated for the relief of moderate to severe acute pain. The long-acting formulation serves as a continuous, around-the-clock analgesic that is indicated for the relief of moderate to severe chronic pain or neuropathic pain associated with diabetic peripheral neuropathy.
DB06210EltrombopagThrombopoietin receptor agonists are pharmaceutical agents that stimulate platelet production in the bone marrow. In this, they differ from the previously discussed agents that act by attempting to curtail platelet destruction.
DB06217VernakalantIndicated for the rapid conversion of recent onset of atrial fibrillation to sinus rhythm in adults for non-surgery patients that lasts for less than 7 days of duration and post-cardiac surgery patients with atrial fibrillation lasting less than 3 days of duration.
DB06231CaldaretInvestigated for use/treatment in heart disease and myocardial infarction.
DB06251DersalazineInvestigated for use/treatment in inflammatory bowel disease.
DB06276TanomastatInvestigated for use/treatment in pancreatic cancer, lung cancer, ovarian cancer, and osteoarthritis.
DB06280SenicapocInvestigated for use/treatment in anemia (sickle cell) and asthma.
DB06288AmisulprideInvestigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression.
DB06292DapagliflozinDapagliflozin is indicated to improve glycemic control in adult patients with type 2 diabetes mellitus along with diet and exercise[Label,A6757,A6758].
DB06306OnalespibInvestigated for use/treatment in cancer/tumors (unspecified).
DB06313BNC105Investigated for use/treatment in cancer/tumors (unspecified).
DB06334TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
DB06413ArmodafinilInvestigated for use/treatment in sleep disorders, obstructive sleep apnea, schizophrenia and schizoaffective disorders, depression, and bipolar disorders.
DB06421DeclopramideInvestigated for use/treatment in colorectal cancer and inflammatory bowel disease.
DB06446DotarizineInvestigated for use/treatment in migraine and cluster headaches.
DB06465FK-960Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss.
DB06472FradafibanInvestigated for use/treatment in angina.
DB06497AplavirocInvestigated for use/treatment in HIV infection.
DB06578TonabersatInvestigated for use/treatment in migraine and cluster headaches.
DB06640FispemifeneInvestigated for use/treatment in male hormonal deficiencies/abnormalities.
DB06654SafinamideSafinamide is indicated as an add-on treatment to levodopa with or without other medicines for Parkinson’s disease
DB06660SaredutantInvestigated for use/treatment in depression and anxiety disorders.
DB06666LixivaptanInvestigated for use/treatment in hyponatremia and congestive heart failure.
DB06670OdanacatibInvestigated for use/treatment in osteoporosis [A19388].
DB06700DesvenlafaxineDesvenlafaxine is indicated for the treatment of major depressive disorder in adults[A6990,A6991,Label].
DB06702FesoterodineFor the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
DB06704IobenguaneDetection of primary and metastatic pheochromocytoma or neuroblastoma
DB06716FospropofolFor monitored anaesthesia care sedation in patients undergoing diagnostic procedures like bronchoscopy and colonscopy or minor surgical procedures like arthroscopy and bunionectomy.
DB06735EnclomipheneNot Available
DB06770Benzyl alcoholUlesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.
DB06774CapsaicinThe capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.
DB06799MethenamineFor prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug is not used to treat infection and should only be used after appropriate eradication of infection with antimicrobial agents.
DB06802NepafenacFor the treatment of pain and inflammation associated with cataract surgery.
DB06807Phenyl aminosalicylateNot Available
DB070693-Hydroxyhippuric acidNot Available
DB07425SobetiromeNot Available
DB07492BromamphenicolNot Available
DB07565Chloramphenicol succinateNot Available
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB07931HexestrolNot Available
DB08399PICEATANNOLNot Available
DB08604TriclosanTriclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
DB08621ThiamphenicolNot Available
DB08797SalicylamideNot Available
DB08810CinitaprideIt is indicated to treat gastrointestinal disorders associated with motility disturbances like gastroesophageal reflux disease (GERD), non-ulcer dyspepsia and delayed gastric emptying.
DB08814TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders.[L1185] It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke and myocardial infarction.[T93]
DB08820IvacaftorWhen used as monotherapy as the product Kalydeco, ivacaftor is indicated for the managmenet of CF in patients age 2 years and older who have a mutation in the CFTR gene that is responsive to ivacaftor potentiation. Ivacaftor received expanded approval in May 2017 for the following 33 CFTR mutations: E56K, P67L, R74W, D110E, D110H, R117C, R117H, G178R, E193K, L206W, R347H, R352Q, A455E, S549N, S549R, G551D, G551S, D579G, S945L, S977F, F1052V, K1060T, A1067T, G1069R, R1070Q, R1070W, F1074L, D1152H, G1244E, S1251N, S1255P, D1270N, and G1349D [L768, FDA Label]. When used in combination with the drug [DB09280] as the product Orkambi, ivacaftor is indicated for the management of CF patients age 6 years and older who are homozygous for the F508del mutation in the CFTR gene.
DB08880TeriflunomideUsed in the treatment of relapsing forms of multiple sclerosis (MS).
DB08896RegorafenibRegorafenib is indicated for the treatment of patients with metastatic colorectal cancer (CRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if KRAS wild type, an anti-EGFR therapy. Regorafenib is also indicated for the treatment of patients with locally advanced, unresectable or metastatic gastrointestinal stromal tumor (GIST) who have been previously treated with imatinib mesylate and sunitinib malate.
DB08945Iotroxic acidNot Available
DB08946Iopanoic acidNot Available
DB08947IopamidolNot Available
DB08948IodamideNot Available
DB08950IndoraminNot Available
DB08955IbuproxamNot Available
DB08976FloctafenineNot Available
DB08983EtofibrateNot Available
DB08984EtofenamateNot Available
DB08989EtamivanNot Available
DB09018BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the GI tract.
DB09020Bisacodyl Indicated for cleansing of the colon as a preparation for colonoscopy in adults.
DB09038EmpagliflozinEmpagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes.
DB09064CiprofibrateNot Available
DB09078LenvatinibLenvatinib is indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer.
DB09082VilanterolVilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
DB09085TetracaineThe combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
DB09088AmylocaineThe most common indication for the usage of amylocaine was spinal anesthesia [A32277].
DB09089TrimebutineIndicated for symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
DB09096Benzoyl peroxideBenzoyl peroxide is indicated for the treatment of mild to moderate acne vulgaris and rosacea. Combined with other agents, it may be used in the treatment of more severe acne.
DB09120ZucapsaicinIndicated to be used in conjunction with oral COX-2 inhibitors or NSAIDs for the relief of severe pain in adult patients with osteoarthritis of the knee, not controlled with oral COX-2 inhibitors or NSAIDs alone, for a duration of no more than three months.
DB09133Iothalamic acidConray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, endoscopic retrograde cholangiopancreatography, contrast enhancement of computed tomographic brain images, cranial computerized angiotomography, intravenous digital subtraction angiography and arterial digital subtraction angiography. Conray may also be used for enhancement of computed tomographic scans performed for detection and evaluation of lesions in the liver, pancreas, kidneys, abdominal aorta, mediastinum, abdominal cavity and retroperitoneal space.
DB09134IoversolOptiray 350 is indicated in adults for peripheral and coronary arteriography and left ventriculography. Optiray 350 is also indicated for contrast enhanced computed tomographic imaging of the head and body, intravenous excretory urography, intravenous digital subtraction angiography and venography. Optiray 350 is indicated in children for angiocardiography. Optiray 320 is indicated in adults for angiography throughout the cardiovascular system. The uses include cerebral, coronary, peripheral, visceral and renal arteriography, venography, aortography, and left ventriculography. Optiray 320 is also indicated for contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 320 is indicated in children for angiocardiography, contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 300 is indicated for cerebral angiography and peripheral arteriography. Optiray 300 is also indicated for contrast enhanced computed tomographic imaging of the head and body, venography, and intravenous excretory urography. Optiray 240 is indicated for cerebral angiography and venography. Optiray 240 is also indicated for contrast enhanced computed tomographic imaging of the head and body and intravenous excretory urography.
DB09135IoxilanWhen administered intra-arterially, Ioxilan is indicated for the following diagnostic tests: cerebral arteriography (300 mgI/mL), coronary arteriography and left ventriculography (350 mgI/mL), visceral angiography(350 mgI/mL), aortography(350 mgI/mL), and peripheral arteriography(350 mgI/mL). When administered intravenously, Ioxilan is indicated for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body (300 and 350 mgI/mL).
DB09143SonidegibSonidegib is approved for use in the US and EU for treatment of adults with locally advanced basal cell carcinoma (BCC) that has recurred post surgery or radiation therapy. It is also approved for adult patients with BCC who are not eligible for surgery or radiation therapy. (2)
DB09148Florbetaben (18F)Florbetaben is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer’s Disease (AD) and other causes of cognitive decline.
DB09156IopromideIopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction angiography (IA-DSA) (150 mg I/mL) Cerebral arteriography and peripheral arteriography (300 mg I/mL) Coronary arteriography and left ventriculography, visceral angiography and aortography (370 mg I/mL) Peripheral venography (240 mg I/mL) Excretory urography (300 mg I/mL) Contrast computed tomography (CT) imaging of head and body (300 mg I/mL and 370 mg I/mL)
DB09216Tolfenamic AcidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.[L1293]
DB09235EfonidipineFor the treatment of hypertension.
DB09254CaroxazoneFor the treatment of depression.
DB09279FimasartanUsed for the treatment of hypertension and heart failure [A20319].
DB09285Morniflumate Morniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for the treatment of pain associated with ear, nose, throat (ENT) and gastrointestinal inflammatory conditions in children. Morniflumate is a well established NSAID that has been in use for over three decades in Italy (particularly for the treatment of upper respiratory tract infections in children), France, Belgium, Austria, Switzerland, Spain and Portugal; it has a generally favorable tolerability profile.
DB09313Ioxaglic acidThis medicinal product is for diagnostic use only in adults and children as a low-osmolality medium [L1883], [A7924].
DB09320Procaine benzylpenicillinFor the treatment of a number of bacterial infections such as syphilis, anthrax, mouth infections, pneumonia and diphtheria.
DB09333Iopodic acidIopodic acid is available as a cholecystographic agent. This denomination indicates the iopodic acid is a radiopaque substance that can be used to visualize the gallbladder and biliary channels in abdominal X-ray.[L1587, A32087] An abdominal X-ray uses a minimal amount of ionizing radiation to produce pictures of the inside of the abdominal cavity. It is commonly used to evaluate the stomach, liver, intestines, and spleen.[L1589] Iopodic acid has also been indicated for the treatment of hyperthyroidism such as Graves disease.[A32085, A32086] Hyperthyroidism refers to any condition where there is too much thyroid hormone produced in the body (overactive thyroid). When the overactivity involves the entire thyroid gland, it is known as Grave's disease.[L1590]
DB09340Tyropanoic acidFor use in cholecystography (X-ray diagnosis/imaging of gallstones).
DB09342PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures [L1591]. It has been combined with procaine to accelerate its onset of action and provide longer-lasting anesthetic effect [L1592]. It was produced for use when amide local anesthetics were contraindicated due to allergy or when several amide anesthetics were unsuccessful [L1592].
DB09346Metrizoic acidFor use as a contrast medium [L1597].
DB09347Acetrizoic acidAcetrizoic acid indication was to be used as a contrast agent for X-ray. Some information indicates its nephrotropic property as one of the characteristics for the utilization of acetrizoic acid.[A32135] The X-ray imaging depends on the difference in tissue density which is provided by an X-ray attenuation between the area of interest and the surrounding tissue. The use of contrast agents will provoke a contrast enhancement or opacification and it will improve the differentiation of pathological processes from normal tissue.[T125]
DB09403Iocetamic acidNot Available
DB09487IotrolanNot Available
DB09516MequinolMequinol is currently primarily available only as an active ingredient in combination products combined with tretinoin that are indicated for the treatment of solar lentigines and related hyperpigmented lesions resulting from chronic sun exposure [FDA Label].
DB09526HydroquinoneHydroquinone is used as an OTC topical lightening agent for disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots and freckles.
DB09543Methyl salicylateOintments or liniments containing methyl salicylate are applied topically as counter irritant for relief of acute pain associated with lumbago,sciatica and rheumatic conditions. Local analgesics for human and veterinary medicine.
DB11062OctisalateIngredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
DB11064HomosalateAs ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
DB11071Phenyl salicylatePain and fever [L2468].
DB11079Trolamine salicylateIndicated for the temporary relief of aches, and pains of muscles and joints associated with backache, lumbago, strains, bruises, sprains and arthritic or rheumatic pain, pain of tendons and ligaments [L1791].
DB11085ResorcinolContemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L2727, F61] or as topical antibacterial skin treatment products for conditions like acne, seborrheic dermatitis, eczema, and others [L2746, L2745, L2744, L2727, F61].
DB11096MeradimateMeradimate is used as an active ingredient in sunscreens or as a sunblock factor in different products. It fits under the category of broad-spectrum absorbent agent. These characteristics are important to consider due to the fact that this kind of ingredients can either absorb or reflect UV radiation. It is also important to know the type of rays that cover. UVA rays are the responsible of causing sun damage and reaching deeper layers of the skin while UVB can only cause sunburn in the outer layer of the skin. When an agent is of broad spectrum, this means that this agent is capable of acting in both UVA and UVB rays.[L2749]
DB11121ChloroxylenolThe predominant medical applications for which chloroxylenol is formally indicated for therapeutic use is as an application to the skin for use in cuts, bites, stings, abrasions, and for use as antiseptic hand cleaner [L1992].
DB11143CresolThe primary medical indications for cresols in general include being used as bactericides, pesticides, and disinfectants [L2020]. Certain isomers of cresol, like m-cresol, may be used as inactive ingredients for the purpose of serving as a preservative in some pharmaceuticals [L2020]. Conversely, many other active pharmaceuticals are also derivatives of various cresol isomer precursors or intermediates [L2049].
DB11148ButambenButamben was indicated for the treatment of chronic pain due to its long-duration effect.[A32663] It is also indicated as a surface anesthetic for skin a mucous membrane and for the relief of pain and pruritus associated with anorectal disorders.[L2445]
DB11155TriclocarbanTriclocarban (TCC), or 3,4,4'-trichlorocarbanilide, is an antibacterial agent used in bar and liquid soaps and body washes [L2685].
DB11160PhenyltoloxamineThe primary therapeutic use for which phenyltoloxamine is currently indicated is as an adjuvant therapy in various combination products containing an analgesic(s) (either narcotic or non-narcotic), where it is expected to potentiate the pain relieving, anti-tussive, etc. effect(s) of the analgesic component of the product. In that regard, some of these aforementioned combination products are typically indicated for the temporary relief of minor aches and pains like headache, muscular aches, backaches, minor arthritis pain, common cold, toothaches, menstrual cramps, etc [L2499]; or perhaps for the treatment of exhausting or non-productive cough, associated with cold or with upper respiratory allergic condition that does not respond to non-narcotic antitussives [L2495].
DB11185SulisobenzoneSunscreening agents are used to prevent sunburn, actinic keratosis, and premature skin aging and to reduce the incidence of skin cancer [L2664].
DB11206BemotrizinolIndicated as an active sunscreen agent.
DB11221DioxybenzoneIndicated for use as an active sunscreen agent.
DB11229Padimate ANot Available
DB11254HexylresorcinolHexylresorcinol is predominantly employed as the active ingredient in lotions, sprays, or lozenges indicated as a (a) topical antiseptic to help prevent skin infection in minor cuts, scrapes, or burns, or (b) as an antiseptic and local anesthetic for the relief of a sore throat and its associated pain [L2734, L2735]. In addition, hexylresorcinol is used as an active ingredient in various commercial cosmetic skincare products as an anti-aging cream [L2736] while other studies have looked into whether or not the compound could be used effectively as an anti-inflammatory agent or even as an anti-cancer therapy [L2736].
DB11263PolydatinNot Available
DB11268ProtocatechualdehydeNot Available
DB11269Diethylamino hydroxybenzoyl hexyl benzoateIndicated for use as a sunscreen agent.
DB11282DiethyltoluamideDiethyltoluamide, or DEET, is an active ingredient that is predominantly indicated for as an insect repellant used to repel biting pests like mosquitoes and ticks [L2774]. Products containing DEET currently are available to the public in a variety of liquids, lotions, sprays, and impregnated materials like towelettes or roll-ons [L2774].
DB11323Glycol salicylateThis drug is only recommended for topical usages for the relief of muscular and rheumatic pain in human and animals [L2687].
DB11324Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient [L2641], [A32884], [L2642].
DB11359GuaiacolIt is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
DB11373AmitrazNot Available
DB11396DichlorophenNot Available
DB11413FlorfenicolNot Available
DB11424LufenuronNot Available
DB11478ZeranolNot Available
DB11480ZoaleneNot Available
DB11502ButacaineNot Available
DB11521ImidocarbNot Available
DB11552TricaineNot Available
DB11558TolueneUsed for the removal of ascarids (Toxocara canis and Toxascaris leonina) and hookworms (Ancylostoma caninum and Uncinaria stenocephala) and as an aid in removing tapeworms (Taenia pisiformis, Dipylidium caninum, and Echinococcus granulosus) from dogs and cats.
DB11570Padimate OIndicated as an active UV-B filter to prevent photodamage.
DB11662RabusertibNot Available
DB11671AZD-4877Not Available
DB11672CurcuminNo approved therapeutic indications.
DB11675MosaprideNot Available
DB11694IlorasertibNot Available
DB11702Antineoplaston A10Not Available
DB11703AcalabrutinibAcalabrutinib is currently indicated for the treatment of adult patients with Mantle Cell Lymphoma (MCL) who have received at least one prior therapy [FDA Label].
DB11704AdomeglivantNot Available
DB11705IomeprolNot Available
DB11706RaxatrigineNot Available
DB11711NavarixinNot Available
DB11732LasmiditanNot Available
DB11763MomelotinibNot Available
DB11778DanusertibNot Available
DB11800TivozanibNot Available
DB11804AZD-5672Not Available
DB11821DanegaptideNot Available
DB11824TofogliflozinNot Available
DB11830MocetinostatNot Available
DB11831DinitrochlorobenzeneNot Available
DB11841EntinostatNot Available
DB11853RelugolixNot Available
DB11855RevefenacinRevefenacin is indicated as an inhalation solution for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD).[L4820] COPD is a growing disease being the third leading cause of death in the US. This disease is characterized by not fully reversible airflow limitation.[L4821]
DB11871PF-00610355Not Available
DB11881AUY922Not Available
DB11886InfigratinibNot Available
DB11904FlumatinibNot Available
DB11941TasisulamNot Available
DB11957IdalopirdineNot Available
DB11978GlasdegibGlasdegib, in combination with cytarabine, is indicated for the treatment of newly diagnosed acute myeloid leukemia in adult patients who are over 75 years old or that have co-morbidities that preclude intensive induction chemotherapy.[L5080] Acute myeloid leukemia is characterized by abnormal production of myeloblasts, red cells, or platelets. It is considered a cancer of blood and bone marrow and it is the most common type of acute leukemia in adults.[L4832]
DB11986EntrectinibNot Available
DB12013AxelopranNot Available
DB12087Vanillyl alcoholNot Available
DB12113CE-224535Not Available
DB12122FigopitantNot Available
DB12135ElubrixinNot Available
DB12179SecoisolariciresinolNot Available
DB12195VP-14637Not Available
DB12206N-6022Not Available
DB12226TerameprocolNot Available
DB12239BalicatibNot Available
DB12254ABT-751Not Available
DB12289DarexabanNot Available
DB12299BavisantNot Available
DB12312ORG-25435Not Available
DB12320PalovaroteneNot Available
DB12323RadotinibRadotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such as patients resistant or intolerant to imatinib.
DB12325IdasanutlinNot Available
DB12341LY-2456302Not Available
DB12355NetazepideNot Available
DB12364BetrixabanBetrixaban is indicated for prophylaxis of venous thromboembolism (VTE) in conditions of moderate to severe restricted mobility or in patients that qualify as in risk of VTE.
DB12371SiponimodThis drug is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults [FDA label].
DB12407IobitridolNot Available
DB12429CI-1040Not Available
DB12439IoforminolNot Available
DB12445NitroaspirinNot Available
DB12448LifibrolNot Available
DB12450Propyl GallateNot Available
DB12482AcotiamideNot Available
DB12518RacloprideNot Available
DB12524BI-671800Not Available
DB12563MK-0686Not Available
DB12574LY-295501Not Available
DB12577FosbretabulinNot Available
DB12585OndelopranNot Available
DB12594AZD-9056Not Available
DB12596CombretastatinNot Available
DB12608EmixustatNot Available
DB12632JNJ-41443532Not Available
DB12681SalirasibNot Available
DB12717MibampatorNot Available
DB12744CGI-1842Not Available
DB12792BoscalidNot Available
DB12798RelenoprideNot Available
DB12800CHF-6001Not Available
DB12802PicropodophyllinNot Available
DB12805AtaciguatNot Available
DB12823TecarfarinNot Available
DB12838TetrasulNot Available
DB12850EtalocibNot Available
DB12853DA-6886Not Available
DB12887TazemetostatNot Available
DB12933RO-4987655Not Available
DB12934GranotapideNot Available
DB12944PhloroglucinolNot Available
DB12996ActeosideNot Available
DB13016LY-2300559Not Available
DB13025TiaprideTiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.
DB13027TucaresolNot Available
DB13039AminaphthoneNot Available
DB13086SCYX-7158Not Available
DB13154ParachlorophenolUsed as an intermediate in organic synthesis of dyes and drugs. Local antibacterial agent in root canal therapy, as topical antiseptic in ointments
DB13205TeclozanNot Available
DB13212PhenolsulfonphthaleinNot Available
DB13215SulfobromophthaleinNot Available
DB13236StibophenNot Available
DB13237ClofoctolNot Available
DB13265HexobendineNot Available
DB13269Dichlorobenzyl alcoholDichlorobenzyl alcohol in combination with [DB13908] is available in over-the-counter products used for symptomatic relief of acute sore throat and postoperative sore throat.[A27155]
DB13271Wood creosoteNot Available
DB13273SultoprideNot Available
DB13278BucetinNot Available
DB13305TolpropamineNot Available
DB13309BenproperineNot Available
DB13346BufexamacIndicated for the treatment of various skin conditions, such as atopic eczema and other inflammatory dermatoses.
DB13428Iobenzamic acidNot Available
DB13433SimfibrateNot Available
DB13439FenpipraneNot Available
DB13444Ioxitalamic acidIoxitalamate in both of its available forms is indicated for exploration of the digestive tract by tomodensitometry or by regular gastroduodenal radiography. Its use is restrained to the cases in which the administration of barium sulfate is not recommended or contraindicated.[F55] The intravascular administration of ioxitalamate is contraindicated as it may present significant side effects.[F54]
DB13472CyclofenilNot Available
DB13483EtamsylateNot Available
DB13492PolicresulenNot Available
DB13509AloxiprinNot Available
DB13511CleboprideNot Available
DB13512ClefamideNot Available
DB13523VeraliprideNot Available
DB13529Dobesilic acidNot Available
DB13538GuacetisalNot Available
DB13539Iodoxamic acidNot Available
DB135494-dimethylaminophenolNot Available
DB13550BifemelaneNot Available
DB13558MorclofoneNot Available
DB13559RimiterolNot Available
DB13612Carbaspirin calciumNot Available
DB13616MelagatranNot Available
DB13628Ethyl hydroxybenzoateNot Available
DB13653LorcainideNot Available
DB13657BenorilateNot Available
DB13701Ioglicic acidNot Available
DB13713QuifenadineNot Available
DB13741Ioglycamic acidNot Available
DB13755Iocarmic acidNot Available
DB13757EpanololNot Available
DB13818BibrocatholNot Available
DB13849ClofibrideNot Available
DB13853Anethole trithioneThe most typical uses for which anethol trithione is currently indicated for includes increasing salivary secretion in patients experiencing dry mouth or being used as an adjunctive therapy for cholecystitis, gallstone, indigestion, and acute/chronic hepatitis [A32614, A32616, L2377]. In addition, although some studies have suggested that anethol trithione also possesses a certain capacity to inhibit tumorigenesis as a potential cancer therapy medication, the specific mechanism of action for this effect remains to be elucidated [A32619] with certain national cancer institutes listing the agent as 'a substance that is being studied in the treatment of cancer' [L2373].
DB13855NifuroxazideNot Available
DB13860Imidazole salicylateNot Available
DB13861IopentolNot Available
DB13864Hemoglobin crosfumarilNot Available
DB13873Fenofibric acidFor use as an adjunctive therapy to diet to: (a) reduce triglyceride levels in adult patients with severe hypertriglyceridemia, and (b) reduce elevated total cholesterol, low-density-lipoprotein (LDL-C), triglycerides, and apolipoprotein B, and to increase high-density-lipoprotein (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). [FDA Label]
DB13877IniparibNot Available
DB13908AmylmetacresolSore throat, minor mouth and throat infections [L2570], [L2571], [A32773].
DB13909Bismuth subgallateThe most common medical purpose for which bismuth subgallate is currently and formally indicated for is the use as a non-prescription internal deodorant product for the purpose of deodorizing flatulence and stools [L2309, L2312, A32566]. Additionally, there are also various non-prescription (over the counter) bismuth subgallate based wound healing products as well as ongoing studies into whether or not the substance can be utilized as a legitimate hemostatic agent - usually for soft tissue surgery in otorhinolaryngology and/or dermatologic settings [A32567, A32568, A32569, A32570]. Moreover, in the past bismuth subgallate may have seen some use as a treatment for Helicobacter pylori infection [A32571]. In contrast, contemporary first-line therapies generally involve proton pump inhibitor and antibiotic combination therapies that generally achieve high rates of pathogen eradication, ease of administration, and patient compliance.
DB13918Diclofop-methylNot Available
DB13931NetarsudilNetarsudil is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension [FDA Label].
DB139631,2-dichlorobenzeneNot Available
DB13988SB-269970Not Available
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due to orthodontic devices in children [L2135].
DB14026Thiosalicylic acidNot Available
DB08044ABT-341Not Available
DB14060NS-398Not Available
DB14083Bisphenol A diglycidyl etherNot Available
DB14084ButylparabenNot Available
DB14127SacubitrilatNot Available
DB14129MacelignanNot Available
DB14144p-AminophenolNot Available
DB14176BenzylparabenBenzylparaben is used in allergenic testing.
DB14177PropylparabenPropylparaben is used in allergenic testing.
DB13735Potassium GuaiacolsulfonateNot Available
DB14212MethylparabenNot Available
DB14232DeacetylbisacodylNot Available
DB11427MaropitantNot Available
DB14658Chloramphenicol palmitateNot Available
DB14668Dienestrol diacetateNot Available
DB14680Combretastatin A4Not Available
DB06422TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB07338AcifluorfenNot Available
DB14708TosylchloramideNot Available
DB14720BrovanexineNot Available
DB02130Vanillic acidNot Available
DB03176KB-141Not Available
DB03523BrequinarNot Available
DB036104-(trifluoromethyl)phenolNot Available
DB07101PD-0325901Not Available
DB07941PH-797804Not Available
DB12020TecovirimatSmallpox virus infection is an inhibitor of the orthopoxvirus VP37 envelope wrapping protein and is indicated for the treatment of human smallpox disease in adults and pediatric patients weighing at least 13 kg [FDA label].
DB12177EplivanserinNot Available
DB12555NelotanserinNot Available
DB12874QuizartinibNot Available
DB14753HydroxystilbamidineUsed in the treatment of nonprogressive blastomycosis of the skin and other mycoses.
DB01460DiethyltryptamineNot Available
DB09298SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
DB09026AliskirenFor the treatment of hypertension, to lower blood pressure.
DrugDrug NameTargetType
DB00179MasoprocolArachidonate 5-lipoxygenasetarget
DB00179MasoprocolCytochrome P450 2J2enzyme
DB00179MasoprocolSex hormone-binding globulintarget
DB00233Aminosalicylic Acid2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
DB00233Aminosalicylic AcidGroup IIE secretory phospholipase A2target
DB00233Aminosalicylic AcidProstaglandin G/H synthase 2target
DB00233Aminosalicylic AcidArachidonate 5-lipoxygenasetarget
DB00233Aminosalicylic AcidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00233Aminosalicylic AcidMyeloperoxidaseenzyme
DB00244MesalazineProstaglandin G/H synthase 1target
DB00244MesalazineProstaglandin G/H synthase 2target
DB00244MesalazinePeroxisome proliferator-activated receptor gammatarget
DB00244MesalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00244MesalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00244MesalazineArachidonate 5-lipoxygenasetarget
DB00244MesalazineArylamine N-acetyltransferasetarget
DB00244MesalazineArylamine N-acetyltransferase 1enzyme
DB00255DiethylstilbestrolEstrogen receptor alphatarget
DB00255DiethylstilbestrolEstrogen-related receptor gammatarget
DB00255DiethylstilbestrolCatechol O-methyltransferaseenzyme
DB00255DiethylstilbestrolCytochrome P450 19A1enzyme
DB00255DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DB00255DiethylstilbestrolMultidrug resistance protein 1transporter
DB00255DiethylstilbestrolEstrogen receptor betatarget
DB00255DiethylstilbestrolCytochrome P450 3A4enzyme
DB00255DiethylstilbestrolCytochrome P450 2C8enzyme
DB00255DiethylstilbestrolCytochrome P450 2C9enzyme
DB00255DiethylstilbestrolCytochrome P450 2E1enzyme
DB00255DiethylstilbestrolSteroid hormone receptor ERR1target
DB00255DiethylstilbestrolSteroid hormone receptor ERR2target
DB00255DiethylstilbestrolNuclear receptor coactivator 2target
DB00255DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DB00255DiethylstilbestrolAndrogen receptortarget
DB00255DiethylstilbestrolSex hormone-binding globulintarget
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DB00255DiethylstilbestrolBile salt export pumptransporter
DB00258Calcium acetatePhosphatetarget
DB00269ChlorotrianiseneEstrogen receptor alphatarget
DB00269ChlorotrianiseneCytochrome P450 19A1enzyme
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00323TolcaponeCatechol O-methyltransferasetarget
DB00323TolcaponeCytochrome P450 2C9enzyme
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineMultidrug resistance protein 1transporter
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00342TerfenadineBile salt export pumptransporter
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00348Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
DB00379MexiletineSodium channel protein type 5 subunit alphatarget
DB00379MexiletineCytochrome P450 1A2enzyme
DB00379MexiletineCytochrome P450 2D6enzyme
DB00379MexiletineCytochrome P450 2B6enzyme
DB00379MexiletineCytochrome P450 2E1enzyme
DB00379MexiletineCytochrome P450 3A4enzyme
DB00379MexiletineAryl hydrocarbon receptortarget
DB00391SulpirideD(2) dopamine receptortarget
DB00391SulpirideD(3) dopamine receptortarget
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibMultidrug resistance protein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB00409RemoxiprideD(2) dopamine receptortarget
DB00409RemoxiprideD(4) dopamine receptortarget
DB00409Remoxipride5-hydroxytryptamine receptor 2Atarget
DB00409RemoxiprideSigma non-opioid intracellular receptor 1target
DB00409RemoxiprideD(3) dopamine receptortarget
DB00409RemoxiprideCytochrome P450 2D6enzyme
DB00423MethocarbamolCarbonic anhydrase 1target
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00446ChloramphenicolCytochrome P450 2C8enzyme
DB00481RaloxifeneEstrogen receptor alphatarget
DB00481RaloxifeneEstrogen receptor betatarget
DB00481RaloxifeneAldehyde oxidaseenzyme
DB00481RaloxifeneCytochrome P450 2C8enzyme
DB00481RaloxifeneCytochrome P450 2B6enzyme
DB00481RaloxifeneCytochrome P450 19A1enzyme
DB00481RaloxifeneCytochrome P450 3A4enzyme
DB00481RaloxifeneSerpin B9target
DB00481RaloxifeneTrefoil factor 1target
DB00481RaloxifeneUDP-glucuronosyltransferase 1-1enzyme
DB00481RaloxifeneSerum albumincarrier
DB00481RaloxifeneAlpha-1-acid glycoprotein 1carrier
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B1transporter
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B3transporter
DB00481RaloxifeneMultidrug resistance protein 1transporter
DB00481RaloxifeneATP-binding cassette sub-family G member 2transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 1transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 2transporter
DB00481RaloxifeneMultidrug resistance-associated protein 4transporter
DB00481RaloxifeneUDP-glucuronosyltransferase 1-10enzyme
DB00481RaloxifeneUDP-glucuronosyltransferase 1-8enzyme
DB00494EntacaponeCatechol O-methyltransferasetarget
DB00494EntacaponeCatechol O-methyltransferaseenzyme
DB00494EntacaponeUDP-glucuronosyltransferase 1-9enzyme
DB00494EntacaponeCytochrome P450 2D6enzyme
DB00522BentiromideSerine protease hepsintarget
DB00539ToremifeneEstrogen receptor alphatarget
DB00539ToremifeneCytochrome P450 3A4enzyme
DB00539ToremifeneMultidrug resistance protein 1transporter
DB00539ToremifeneCytochrome P450 1A1enzyme
DB00539ToremifeneSex hormone-binding globulintarget
DB00549ZafirlukastCysteinyl leukotriene receptor 1target
DB00549ZafirlukastCytochrome P450 2C9enzyme
DB00549ZafirlukastCytochrome P450 2C8enzyme
DB00549ZafirlukastProstaglandin G/H synthase 1enzyme
DB00549ZafirlukastCytochrome P450 3A4enzyme
DB00549ZafirlukastCytochrome P450 1A2enzyme
DB00549ZafirlukastCytochrome P450 2C19enzyme
DB00549ZafirlukastCytochrome P450 2E1enzyme
DB00549ZafirlukastATP-binding cassette sub-family G member 2transporter
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBCR/ABL fusion protein isoform X9target
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibMultidrug resistance protein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB00636ClofibratePeroxisome proliferator-activated receptor alphatarget
DB00636ClofibrateCytochrome P450 3A4enzyme
DB00636ClofibrateGlutathione S-transferase A2enzyme
DB00636ClofibrateCytochrome P450 2E1enzyme
DB00636ClofibrateCytochrome P450 1A1enzyme
DB00636ClofibrateCytochrome P450 2A6enzyme
DB00636ClofibrateCytochrome P450 2B6enzyme
DB00636ClofibrateCytochrome P450 4A11enzyme
DB00636ClofibrateThyroxine-binding globulincarrier
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenThyroxine-binding globulincarrier
DB00678LosartanType-1 angiotensin II receptortarget
DB00678LosartanCytochrome P450 3A4enzyme
DB00678LosartanCytochrome P450 2C9enzyme
DB00678LosartanCytochrome P450 2C8enzyme
DB00678LosartanMultidrug resistance protein 1transporter
DB00678LosartanSolute carrier family 22 member 6transporter
DB00678LosartanUDP-glucuronosyltransferase 1-1enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-3enzyme
DB00678LosartanUDP-glucuronosyltransferase 1-10enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B7enzyme
DB00678LosartanUDP-glucuronosyltransferase 2B17enzyme
DB00678LosartanCytochrome P450 2C19enzyme
DB00678LosartanSerum albumincarrier
DB00678LosartanSolute carrier family 22 member 12transporter
DB00678LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
DB00678LosartanBile salt export pumptransporter
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00712FlurbiprofenProstaglandin G/H synthase 2target
DB00712FlurbiprofenProstaglandin G/H synthase 1target
DB00712FlurbiprofenCytochrome P450 2C9enzyme
DB00712FlurbiprofenSerum albumincarrier
DB00712FlurbiprofenMultidrug resistance-associated protein 4transporter
DB00712FlurbiprofenSolute carrier family 22 member 6transporter
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcainePhospholipase A2target
DB00721ProcaineMonoamine oxidasetarget
DB00737MeclizineHistamine H1 receptortarget
DB00737MeclizineNuclear receptor subfamily 1 group I member 3target
DB00745ModafinilSodium-dependent dopamine transportertarget
DB00745ModafinilAlpha-1B adrenergic receptortarget
DB00745ModafinilCytochrome P450 3A4enzyme
DB00745ModafinilCytochrome P450 2C19enzyme
DB00745ModafinilCytochrome P450 1A2enzyme
DB00745ModafinilCytochrome P450 2B6enzyme
DB00745ModafinilCytochrome P450 2C9enzyme
DB00745ModafinilCytochrome P450 3A5enzyme
DB00756HexachloropheneD-lactate dehydrogenasetarget
DB00756HexachloropheneGlutamate dehydrogenase 1, mitochondrialtarget
DB00756HexachloropheneSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialtarget
DB00756HexachloropheneEstrogen receptor alphatarget
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideMultidrug resistance protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2C8enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00796Candesartan cilexetilType-1 angiotensin II receptortarget
DB00796Candesartan cilexetilCytochrome P450 2C8enzyme
DB00796Candesartan cilexetilCytochrome P450 2C9enzyme
DB00796Candesartan cilexetilMultidrug resistance protein 1transporter
DB00796Candesartan cilexetilUDP-glucuronosyltransferase 1-3enzyme
DB00796Candesartan cilexetilProstaglandin G/H synthase 1enzyme
DB00807ProparacaineSodium channel protein type 10 subunit alphatarget
DB00818PropofolCytochrome P450 2B6enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-1enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-9enzyme
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-2target
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-3target
DB00818PropofolSerum albumincarrier
DB00818PropofolSodium channel protein type 4 subunit alphatarget
DB00818PropofolSodium channel protein type 2 subunit alphatarget
DB00818PropofolFatty-acid amide hydrolase 1enzyme
DB00818PropofolCytochrome P450 2C9enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-8enzyme
DB00818PropofolCytochrome P450 2E1enzyme
DB00818PropofolCytochrome P450 1B1enzyme
DB00818PropofolCytochrome P450 1A1enzyme
DB00818PropofolCytochrome P450 1A2enzyme
DB00818PropofolCytochrome P450 2C18enzyme
DB00818PropofolCytochrome P450 2C19enzyme
DB00818PropofolCytochrome P450 2C8enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-6enzyme
DB00818PropofolGABA-A receptor (anion channel)target
DB00861DiflunisalProstaglandin G/H synthase 1target
DB00861DiflunisalProstaglandin G/H synthase 2target
DB00861DiflunisalSerum albumincarrier
DB00861DiflunisalSolute carrier family 22 member 6transporter
DB00861DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DB00861DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DB00874GuaifenesinNMDA receptortarget
DB00882ClomifeneEstrogen receptor alphatarget
DB00882ClomifeneMultidrug resistance protein 1transporter
DB00882ClomifeneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00882ClomifeneCytochrome P450 19A1enzyme
DB00882ClomifeneCytochrome P450 1A1enzyme
DB00882ClomifeneCytochrome P450 1A2enzyme
DB00882ClomifeneCytochrome P450 2E1enzyme
DB00882ClomifeneSex hormone-binding globulintarget
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00890DienestrolEstrogen receptor alphatarget
DB00890DienestrolSex hormone-binding globulintarget
DB00892OxybuprocaineSodium channel protein type 10 subunit alphatarget
DB00895Benzylpenicilloyl PolylysineHigh affinity immunoglobulin epsilon receptor subunit gammatarget
DB00895Benzylpenicilloyl PolylysineHigh affinity immunoglobulin epsilon receptor subunit alphatarget
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00950FexofenadineHistamine H1 receptortarget
DB00950FexofenadineMultidrug resistance protein 1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 2B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1A2transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B3transporter
DB00950FexofenadineSolute carrier family 22 member 8transporter
DB00963BromfenacProstaglandin G/H synthase 1target
DB00963BromfenacProstaglandin G/H synthase 2target
DB00963BromfenacProstaglandin G/H synthase 2enzyme
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanMultidrug resistance protein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00966TelmisartanBile salt export pumptransporter
DB00966TelmisartanUDP-glucuronosyltransferase 1-3enzyme
DB00985DimenhydrinateHistamine H1 receptortarget
DB01014BalsalazideProstaglandin G/H synthase 1target
DB01014BalsalazideProstaglandin G/H synthase 2target
DB01014BalsalazideArachidonate 5-lipoxygenasetarget
DB01014BalsalazidePeroxisome proliferator-activated receptor gammatarget
DB01014BalsalazideNADPH azoreductaseenzyme
DB01029IrbesartanType-1 angiotensin II receptortarget
DB01029IrbesartanTranscription factor AP-1target
DB01029IrbesartanCytochrome P450 2C9enzyme
DB01029IrbesartanCytochrome P450 2C8enzyme
DB01029IrbesartanUDP-glucuronosyltransferase 1-3enzyme
DB01029IrbesartanProstaglandin G/H synthase 1enzyme
DB01029IrbesartanCytochrome P450 3A4enzyme
DB01035ProcainamideSodium channel protein type 5 subunit alphatarget
DB01035ProcainamideDNA (cytosine-5)-methyltransferase 1target
DB01035ProcainamideCytochrome P450 2D6enzyme
DB01035ProcainamideSolute carrier family 22 member 2transporter
DB01035ProcainamideSolute carrier family 22 member 1transporter
DB01035ProcainamideSolute carrier family 22 member 3transporter
DB01035ProcainamideSolute carrier family 22 member 5transporter
DB01035ProcainamideSolute carrier family 22 member 4transporter
DB01035ProcainamidePotassium voltage-gated channel subfamily H member 2target
DB01035ProcainamideMultidrug and toxin extrusion protein 1transporter
DB01035ProcainamideMultidrug and toxin extrusion protein 2transporter
DB01036TolterodineMuscarinic acetylcholine receptor M1target
DB01036TolterodineMuscarinic acetylcholine receptor M2target
DB01036TolterodineMuscarinic acetylcholine receptor M3target
DB01036TolterodineCytochrome P450 2D6enzyme
DB01036TolterodineCytochrome P450 3A4enzyme
DB01036TolterodineCytochrome P450 2C9enzyme
DB01036TolterodineCytochrome P450 2C19enzyme
DB01036TolterodineMuscarinic acetylcholine receptor M4target
DB01036TolterodineMuscarinic acetylcholine receptor M5target
DB01039FenofibratePeroxisome proliferator-activated receptor alphatarget
DB01039FenofibrateCytochrome P450 2C8enzyme
DB01039FenofibrateCytochrome P450 2C9enzyme
DB01039FenofibrateCytochrome P450 3A4enzyme
DB01039FenofibratePeroxisome proliferator-activated receptor gammatarget
DB01039FenofibratePeroxisome proliferator-activated receptor deltatarget
DB01039FenofibrateNuclear receptor subfamily 1 group I member 2target
DB01039FenofibrateUDP-glucuronosyltransferase 1-1enzyme
DB01039FenofibrateBile salt export pumptransporter
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineCytochrome P450 2C18enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineMultidrug resistance protein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01091ButenafineSqualene monooxygenasetarget
DB01121PhenacemideSodium channel protein type 1 subunit alphatarget
DB01128BicalutamideAndrogen receptortarget
DB01128BicalutamideCytochrome P450 3A4enzyme
DB01128BicalutamideCytochrome P450 2C19enzyme
DB01128BicalutamideCytochrome P450 2C9enzyme
DB01128BicalutamideCytochrome P450 2D6enzyme
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01168ProcarbazineXanthine dehydrogenase/oxidaseenzyme
DB01168ProcarbazineCytochrome P450 1B1enzyme
DB01168ProcarbazineMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01171MoclobemideMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01179PodofiloxDNA topoisomerase 2-alphatarget
DB01179PodofiloxTubulin alpha-4A chaintarget
DB01179PodofiloxTubulin beta chaintarget
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideD(2) dopamine receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233MetoclopramideCytochrome P450 11B1, mitochondrialenzyme
DB01233MetoclopramideCytochrome P450 11B2, mitochondrialenzyme
DB01233MetoclopramideSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01237BromodiphenhydramineHistamine H1 receptortarget
DB01237BromodiphenhydramineSolute carrier family 22 member 6transporter
DB01241GemfibrozilPeroxisome proliferator-activated receptor alphatarget
DB01241GemfibrozilCytochrome P450 2C9enzyme
DB01241GemfibrozilCytochrome P450 2C8enzyme
DB01241GemfibrozilCytochrome P450 1A2enzyme
DB01241GemfibrozilCytochrome P450 2C19enzyme
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B1transporter
DB01241GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
DB01241GemfibrozilCytochrome P450 3A4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
DB01250OlsalazineInterferon gammatarget
DB01250OlsalazineThiopurine S-methyltransferasetarget
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB01393BezafibratePeroxisome proliferator-activated receptor alphatarget
DB01393BezafibrateSolute carrier organic anion transporter family member 1B1transporter
DB01393BezafibratePeroxisome proliferator-activated receptor deltatarget
DB01393BezafibratePeroxisome proliferator-activated receptor gammatarget
DB01393BezafibrateCytochrome P450 1A1enzyme
DB01393BezafibrateCytochrome P450 2C8enzyme
DB01393BezafibrateCytochrome P450 3A4enzyme
DB01393BezafibrateNuclear receptor subfamily 1 group I member 2target
DB01393BezafibrateRetinoic acid receptor RXR-alphatarget
DB01393BezafibrateRetinoic acid receptor RXR-betatarget
DB01393BezafibrateRetinoic acid receptor RXR-gammatarget
DB01397Magnesium salicylateSerum albumincarrier
DB01397Magnesium salicylateProstaglandin G/H synthase 1target
DB01397Magnesium salicylateProstaglandin G/H synthase 2target
DB01399SalsalateProstaglandin G/H synthase 1target
DB01399SalsalateProstaglandin G/H synthase 2target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 1target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DB01428OxybenzoneProgesterone receptortarget
DB01428OxybenzoneAndrogen receptortarget
DB01428OxybenzoneEstrogen receptor alphatarget
DB01428OxybenzoneEstrogen receptor betatarget
DB01432CholestyramineBile acidstarget
DB01599ProbucolATP-binding cassette sub-family A member 1target
DB01599ProbucolLiver carboxylesterase 1target
DB01609DeferasiroxCytochrome P450 3A4enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-1enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-3enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-9enzyme
DB01609DeferasiroxCytochrome P450 2C8enzyme
DB01609DeferasiroxCytochrome P450 1A2enzyme
DB01626PargylineAmine oxidase [flavin-containing] Btarget
DB01626PargylineAmine oxidase [flavin-containing] Atarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01656RoflumilastCytochrome P450 3A4enzyme
DB01676TrinitrotoluenePentaerythritol tetranitrate reductasetarget
DB01681Benzene Hexacarboxylic AcidPhosphoglycerate mutase 2target
DB01688P-CresolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB017112,3,4,5,6-Pentafluorobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
DB017262-AminophenolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01878BenzophenoneEstrogen receptor alphatarget
DB01878BenzophenoneEstrogen receptor betatarget
DB01892HyperforinNuclear receptor subfamily 1 group I member 2target
DB01892HyperforinProstaglandin G/H synthase 1target
DB01892HyperforinArachidonate 5-lipoxygenasetarget
DB01892HyperforinCanalicular multispecific organic anion transporter 1transporter
DB01892HyperforinSolute carrier organic anion transporter family member 1B1transporter
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, endothelialtarget
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, inducibletarget
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, braintarget
DB021053,5-DinitrocatecholCatechol O-methyltransferasetarget
DB022321,2-DihydroxybenzeneCatechol 1,2-dioxygenasetarget
DB022321,2-DihydroxybenzeneBiphenyl-2,3-diol 1,2-dioxygenasetarget
DB02266Flufenamic AcidAldo-keto reductase family 1 member C3target
DB02266Flufenamic AcidTransthyretincarrier
DB02266Flufenamic AcidProstaglandin G/H synthase 2target
DB02266Flufenamic AcidProstaglandin G/H synthase 1target
DB02266Flufenamic AcidSolute carrier family 22 member 6transporter
DB02266Flufenamic AcidAndrogen receptortarget
DB02266Flufenamic AcidPeroxisome proliferator-activated receptor alphatarget
DB02266Flufenamic AcidPeroxisome proliferator-activated receptor gammatarget
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB02709ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
DB02709ResveratrolProstaglandin G/H synthase 1target
DB02709ResveratrolCasein kinase II subunit alphatarget
DB02709ResveratrolProstaglandin G/H synthase 2target
DB02709ResveratrolCytochrome P450 1A1enzyme
DB02709ResveratrolCytochrome P450 3A4enzyme
DB02709ResveratrolCytochrome P450 1A2enzyme
DB02709ResveratrolCytochrome P450 1B1enzyme
DB02709ResveratrolArachidonate 15-lipoxygenasetarget
DB02709ResveratrolArachidonate 5-lipoxygenasetarget
DB02709ResveratrolAryl hydrocarbon receptortarget
DB02709ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
DB02709ResveratrolIntegrin alpha-5target
DB02709ResveratrolIntegrin beta-3target
DB02709ResveratrolSerum albumincarrier
DB02709ResveratrolAmyloid beta A4 proteintarget
DB02709ResveratrolEstrogen receptor alphatarget
DB02709ResveratrolMelatonin receptor type 1Atarget
DB02709ResveratrolMelatonin receptor type 1Btarget
DB02709ResveratrolC-type lectin domain family 14 member Atarget
DB02709ResveratrolNuclear receptor subfamily 1 group I member 2target
DB02709ResveratrolNuclear receptor subfamily 1 group I member 3target
DB02709ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
DB02709ResveratrolCarbonyl reductase [NADPH] 1target
DB02709ResveratrolPeroxisome proliferator-activated receptor alphatarget
DB02709ResveratrolPeroxisome proliferator-activated receptor gammatarget
DB02709ResveratrolRAC-alpha serine/threonine-protein kinasetarget
DB02709ResveratrolFar upstream element-binding protein 2target
DB02709ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
DB02715Compound 18Estrogen receptor alphatarget
DB02749Pyromellitic AcidFumarate hydratase class IItarget
DB02795P-Anisic AcidGroup IIE secretory phospholipase A2target
DB02795P-Anisic AcidPhospholipase A2target
DB02822Para-Bromobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
DB028392,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
DB028392,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
DB02877Arotinoid acidRetinoic acid receptor betatarget
DB030582-Aminobenzyl alcoholComplement factor Dtarget
DB030733-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
DB03083IC261Casein kinase I isoform gamma-2target
DB031102-ChlorophenolMitogen-activated protein kinase 14target
DB03120Para-Toluene SulfonateLysozyme Ctarget
DB03120Para-Toluene SulfonatePro-cathepsin Htarget
DB03255PhenolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB03255PhenolSerum albumintarget
DB036443-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
DB03651Picric acidPentaerythritol tetranitrate reductasetarget
DB03728p-Chlorobenzoic acid4-chlorobenzoyl CoA ligasetarget
DB03793Benzoic AcidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic AcidHeat-labile enterotoxin B chaintarget
DB03793Benzoic AcidCocaine esterasetarget
DB03793Benzoic AcidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic AcidTautomerase PptAtarget
DB03793Benzoic AcidD-amino-acid oxidasetarget
DB03793Benzoic AcidRibonuclease UK114target
DB03793Benzoic AcidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic AcidRas-related protein Rab-9Atarget
DB03793Benzoic AcidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic AcidNon-heme chloroperoxidasetarget
DB03793Benzoic AcidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic AcidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic AcidReplication proteintarget
DB03793Benzoic AcidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic AcidSolute carrier family 22 member 8transporter
DB03793Benzoic AcidMonocarboxylate transporter 1transporter
DB03793Benzoic AcidSolute carrier family 15 member 1target
DB040523,4-DimethylphenolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB04098BalanolcAMP-dependent protein kinase catalytic subunit alphatarget
DB04166Anthranilic acidL-amino-acid oxidasetarget
DB04166Anthranilic acidD-amino-acid oxidasetarget
DB04200MatairesinolDehydrogenase/reductase SDR family member 4-like 2target
DB042144-Nitrophenyl PhosphateLow molecular weight phosphotyrosine protein phosphatasetarget
DB042144-Nitrophenyl PhosphateDual specificity protein phosphatase 23target
DB04417P-NitrophenolSulfotransferase 1A1target
DB04417P-NitrophenolAlpha-amylase 2Btarget
DB04468AfimoxifeneEstrogen receptor alphatarget
DB04468AfimoxifeneEstrogen receptor betatarget
DB04468AfimoxifeneEstrogen-related receptor gammatarget
DB04468AfimoxifeneTrefoil factor 1target
DB04468AfimoxifeneSteroid hormone receptor ERR1target
DB04468AfimoxifeneNuclear receptor subfamily 1 group I member 2target
DB04468AfimoxifeneSex hormone-binding globulintarget
DB045282,4-DinitrophenolPentaerythritol tetranitrate reductasetarget
DB045332-Amino-P-CresolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB04586o-BromophenolThymidylate synthasetarget
DB04711IodipamideSerum albumincarrier
DB04824PhenolphthaleinUDP-glucuronosyltransferase 1-9target
DB04824PhenolphthaleinNuclear receptor subfamily 1 group I member 2target
DB04824PhenolphthaleinNuclear receptor subfamily 1 group I member 3target
DB04824PhenolphthaleinEstrogen receptor alphatarget
DB04824PhenolphthaleinSex hormone-binding globulintarget
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget
DB04846CeliprololCytochrome P450 2D6enzyme
DB04862MerimepodibInosine-5'-monophosphate dehydrogenasetarget
DB04863LefradafibanIntegrin alpha-IIbtarget
DB04863LefradafibanIntegrin beta-3target
DB04884Dapoxetine5-hydroxytryptamine receptor 1Atarget
DB04884Dapoxetine5-hydroxytryptamine receptor 1Btarget
DB04884Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DB04884DapoxetineCytochrome P450 3A4enzyme
DB04884DapoxetineCytochrome P450 2D6enzyme
DB04898XimelagatranCytochrome P450 2C9enzyme
DB04905TesmilifeneMultidrug resistance protein 1target
DB04905TesmilifeneHistamine H1 receptortarget
DB04905TesmilifeneCytochrome P450 3A4enzyme
DB04905TesmilifeneCytochrome P450 2D6enzyme
DB04905TesmilifeneCytochrome P450 1A1enzyme
DB04917Renzapride5-hydroxytryptamine receptor 3Atarget
DB04917Renzapride5-hydroxytryptamine receptor 4target
DB04924ItoprideD(2) dopamine receptortarget
DB04938OspemifeneEstrogen receptor alphatarget
DB04938OspemifeneCytochrome P450 3A4enzyme
DB04938OspemifeneCytochrome P450 2C9enzyme
DB04938OspemifeneCytochrome P450 2C19enzyme
DB04938OspemifeneCytochrome P450 2B6enzyme
DB04938OspemifeneCytochrome P450 2D6enzyme
DB04942TamibaroteneRetinoic acid receptor alphatarget
DB04942TamibaroteneRetinoic acid receptor betatarget
DB04942TamibaroteneCellular retinoic acid-binding protein 1carrier
DB05050ADL5859Delta-type opioid receptortarget
DB05073SRT501NAD-dependent protein deacetylase sirtuin-1target
DB05075TG-100801Vascular endothelial growth factor receptor 1target
DB05075TG-100801Vascular endothelial growth factor receptor 2target
DB05075TG-100801Vascular endothelial growth factor receptor 3target
DB05075TG-100801Tyrosine-protein kinase CSKtarget
DB05130INCB3284C-C chemokine receptor type 2target
DB05199LX1031Tryptophan 5-hydroxylase 1target
DB05227APD7915-hydroxytryptamine receptor 2Atarget
DB05289TarenflurbilNF-kappa-B essential modulatortarget
DB05399SuccinobucolVascular cell adhesion protein 1target
DB05470VX-702Mitogen-activated protein kinase 14target
DB05470VX-702Tumor necrosis factortarget
DB05470VX-702Interleukin-1 betatarget
DB05507VX-765Interleukin-1 betatarget
DB05542Naronapride5-hydroxytryptamine receptor 4target
DB05552TG100-115Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB05552TG100-115Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB05678SLx-4090Microsomal triglyceride transfer protein large subunittarget
DB05708GTS-21Neuronal acetylcholine receptor subunit alpha-7target
DB05708GTS-21Cytochrome P450 1A2enzyme
DB05708GTS-21Cytochrome P450 2E1enzyme
DB06070SNX-5422Heat shock protein HSP 90-alphatarget
DB06070SNX-5422Heat shock protein HSP 90-betatarget
DB06080ABT-869Receptor-type tyrosine-protein kinase FLT3target
DB06080ABT-869Vascular endothelial growth factor receptor 1target
DB06080ABT-869Vascular endothelial growth factor receptor 2target
DB06080ABT-869Vascular endothelial growth factor receptor 3target
DB06080ABT-869Mast/stem cell growth factor receptor Kittarget
DB06080ABT-869Macrophage colony-stimulating factor 1 receptortarget
DB06083TapinarofInterleukin-12 subunit betatarget
DB06103VX-148Inosine-5'-monophosphate dehydrogenase 1target
DB06103VX-148Inosine-5'-monophosphate dehydrogenase 2target
DB06134SNS-314Aurora kinase Atarget
DB06134SNS-314Aurora kinase Ctarget
DB06190SolabegronBeta-3 adrenergic receptortarget
DB06204TapentadolMu-type opioid receptortarget
DB06204TapentadolKappa-type opioid receptortarget
DB06204TapentadolDelta-type opioid receptortarget
DB06204TapentadolSodium-dependent noradrenaline transportertarget
DB06204Tapentadol5-hydroxytryptamine receptor 3Atarget
DB06204TapentadolUDP-glucuronosyltransferase 1-9enzyme
DB06204TapentadolUDP-glucuronosyltransferase 2B7enzyme
DB06204TapentadolCytochrome P450 2D6enzyme
DB06204TapentadolCytochrome P450 2C9enzyme
DB06204TapentadolCytochrome P450 2C19enzyme
DB06204TapentadolSodium-dependent serotonin transportertarget
DB06210EltrombopagThrombopoietin receptortarget
DB06210EltrombopagCytochrome P450 2C8enzyme
DB06210EltrombopagCytochrome P450 1A2enzyme
DB06210EltrombopagUDP-glucuronosyltransferase 1-1enzyme
DB06210EltrombopagUDP-glucuronosyltransferase 1-3enzyme
DB06210EltrombopagSolute carrier organic anion transporter family member 1B1transporter
DB06210EltrombopagATP-binding cassette sub-family G member 2transporter
DB06210EltrombopagUDP-glucuronosyltransferase 1-9enzyme
DB06217VernakalantCytochrome P450 2D6enzyme
DB06217VernakalantSodium channel protein type 5 subunit alphatarget
DB06217VernakalantPotassium voltage-gated channel subfamily A member 5target
DB06217VernakalantPotassium voltage-gated channel subfamily D member 3target
DB06217VernakalantPotassium voltage-gated channel subfamily H member 2target
DB06231CaldaretSodium/calcium exchanger 1target
DB06288AmisulprideD(2) dopamine receptortarget
DB06288AmisulprideD(3) dopamine receptortarget
DB06288Amisulpride5-hydroxytryptamine receptor 7target
DB06288Amisulpride5-hydroxytryptamine receptor 2Atarget
DB06292DapagliflozinSodium/glucose cotransporter 2target
DB06292DapagliflozinCytochrome P450 1A1enzyme
DB06292DapagliflozinCytochrome P450 1A2enzyme
DB06292DapagliflozinCytochrome P450 2A6enzyme
DB06292DapagliflozinCytochrome P450 2C9enzyme
DB06292DapagliflozinCytochrome P450 2D6enzyme
DB06292DapagliflozinCytochrome P450 3A4enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 1-9enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 2B4enzyme
DB06292DapagliflozinUDP-glucuronosyltransferase 2B7enzyme
DB06292DapagliflozinMultidrug resistance protein 1transporter
DB06413ArmodafinilCytochrome P450 2C19enzyme
DB06413ArmodafinilCytochrome P450 3A4enzyme
DB06413ArmodafinilCytochrome P450 1A2enzyme
DB06413ArmodafinilCytochrome P450 2B6enzyme
DB06413ArmodafinilCytochrome P450 3A5enzyme
DB06413ArmodafinilCytochrome P450 2C9enzyme
DB06413ArmodafinilSodium-dependent dopamine transportertarget
DB06421DeclopramideDNA topoisomerase 2-alphatarget
DB06421DeclopramideDNA topoisomerase 2-betatarget
DB06446Dotarizine5-hydroxytryptamine receptor 2Atarget
DB06446Dotarizine5-hydroxytryptamine receptor 1Atarget
DB06446DotarizineVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB06446Dotarizine5-hydroxytryptamine receptor 2Ctarget
DB06446DotarizineCytochrome P450 3A4enzyme
DB06472FradafibanIntegrin alpha-IIbtarget
DB06472FradafibanIntegrin beta-3target
DB06497AplavirocC-C chemokine receptor type 5target
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB06654SafinamideCytochrome P450 1A1enzyme
DB06654SafinamideCytochrome P450 1A2enzyme
DB06654SafinamideCytochrome P450 2B6enzyme
DB06654SafinamideCytochrome P450 2C9enzyme
DB06654SafinamideCytochrome P450 2D6enzyme
DB06654SafinamideCytochrome P450 2C19enzyme
DB06654SafinamideCytochrome P450 2E1enzyme
DB06654SafinamideCytochrome P450 3A5enzyme
DB06660SaredutantSubstance-K receptortarget
DB06670OdanacatibCathepsin Ktarget
DB06670OdanacatibMultidrug resistance protein 1carrier
DB06670OdanacatibCytochrome P450 3A4enzyme
DB06670OdanacatibCytochrome P450 2C8enzyme
DB06700DesvenlafaxineCytochrome P450 3A4enzyme
DB06700DesvenlafaxineSodium-dependent serotonin transportertarget
DB06700DesvenlafaxineSodium-dependent noradrenaline transportertarget
DB06700DesvenlafaxineCytochrome P450 2D6enzyme
DB06700DesvenlafaxineSodium-dependent dopamine transportertarget
DB06702FesoterodineMuscarinic acetylcholine receptor M1target
DB06702FesoterodineMuscarinic acetylcholine receptor M3target
DB06702FesoterodineCytochrome P450 3A4enzyme
DB06702FesoterodineMuscarinic acetylcholine receptor M2target
DB06702FesoterodineMuscarinic acetylcholine receptor M4target
DB06702FesoterodineMuscarinic acetylcholine receptor M5target
DB06702FesoterodineCytochrome P450 2D6enzyme
DB06702FesoterodineMultidrug resistance protein 1transporter
DB06704IobenguaneSodium-dependent noradrenaline transportertransporter
DB06716FospropofolGamma-aminobutyric acid receptor subunit beta-2target
DB06716FospropofolGamma-aminobutyric acid receptor subunit beta-3target
DB06716FospropofolAlkaline phosphatase, tissue-nonspecific isozymeenzyme
DB06716FospropofolSerum albumincarrier
DB06735EnclomipheneCytochrome P450 2D6enzyme
DB06770Benzyl alcoholCytochrome P450 2C8enzyme
DB06770Benzyl alcoholCytochrome P450 1A1enzyme
DB06770Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
DB06770Benzyl alcoholCytochrome P450 1A2enzyme
DB06770Benzyl alcoholCytochrome P450 2E1enzyme
DB06770Benzyl alcoholCytochrome P450 2D6enzyme
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB06802NepafenacProstaglandin G/H synthase 1target
DB06802NepafenacProstaglandin G/H synthase 2target
DB070693-Hydroxyhippuric acidKynureninasetarget
DB07425SobetiromeThyroid hormone receptor, alpha isoform 1 varianttarget
DB07425SobetiromeThyroid hormone receptor betatarget
DB07492BromamphenicolDr hemagglutinin structural subunittarget
DB07565Chloramphenicol succinateDr hemagglutinin structural subunittarget
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB07615TranilastCytochrome P450 3A4enzyme
DB07615TranilastCytochrome P450 2C9enzyme
DB07931HexestrolAldo-keto reductase family 1 member C1target
DB07931HexestrolEstrogen receptor alphatarget
DB07931HexestrolNuclear receptor subfamily 1 group I member 2target
DB07931HexestrolNuclear receptor subfamily 1 group I member 3target
DB08399PICEATANNOLATP synthase subunit alpha, mitochondrialtarget
DB08399PICEATANNOLATP synthase subunit beta, mitochondrialtarget
DB08399PICEATANNOLATP synthase subunit gamma, mitochondrialtarget
DB08407PLATENSIMYCIN3-oxoacyl-[acyl-carrier-protein] synthase 2target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
DB08604TriclosanNuclear receptor subfamily 1 group I member 2target
DB08604TriclosanAndrogen receptortarget
DB08604TriclosanNuclear receptor subfamily 1 group I member 3target
DB08604TriclosanPeroxisome proliferator-activated receptor gammatarget
DB08604TriclosanThyroid peroxidasetarget
DB08621ThiamphenicolDr hemagglutinin structural subunittarget
DB087484-(DIMETHYLAMINO)BENZOIC ACIDReplicase polyprotein 1abtarget
DB087484-(DIMETHYLAMINO)BENZOIC ACIDOrf1a polyproteintarget
DB08810Cinitapride5-hydroxytryptamine receptor 1Atarget
DB08810Cinitapride5-hydroxytryptamine receptor 4target
DB08810Cinitapride5-hydroxytryptamine receptor 2Atarget
DB08814TriflusalProstaglandin G/H synthase 1target
DB08814TriflusalNuclear factor NF-kappa-B p105 subunittarget
DB08814TriflusalNitric oxide synthase, inducibletarget
DB08814TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB08814TriflusalSerum albumincarrier
DB08820IvacaftorCystic fibrosis transmembrane conductance regulatortarget
DB08820IvacaftorCytochrome P450 3A4enzyme
DB08820IvacaftorSerum albumincarrier
DB08820IvacaftorAlpha-1-acid glycoprotein 1carrier
DB08820IvacaftorMultidrug resistance protein 1transporter
DB08820IvacaftorCytochrome P450 3A5enzyme
DB08880TeriflunomideATP-binding cassette sub-family G member 2transporter
DB08880TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB08880TeriflunomideCytochrome P450 2C8enzyme
DB08880TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
DB08880TeriflunomideCytochrome P450 1A2enzyme
DB08896RegorafenibCytochrome P450 3A4enzyme
DB08896RegorafenibUDP-glucuronosyltransferase 1-9enzyme
DB08896RegorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB08896RegorafenibVascular endothelial growth factor receptor 1target
DB08896RegorafenibVascular endothelial growth factor receptor 2target
DB08896RegorafenibVascular endothelial growth factor receptor 3target
DB08896RegorafenibMast/stem cell growth factor receptor Kittarget
DB08896RegorafenibPlatelet-derived growth factor receptor alphatarget
DB08896RegorafenibPlatelet-derived growth factor receptor betatarget
DB08896RegorafenibFibroblast growth factor receptor 1target
DB08896RegorafenibFibroblast growth factor receptor 2target
DB08896RegorafenibAngiopoietin-1 receptortarget
DB08896RegorafenibDiscoidin domain-containing receptor 2target
DB08896RegorafenibHigh affinity nerve growth factor receptortarget
DB08896RegorafenibEphrin type-A receptor 2target
DB08896RegorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB08896RegorafenibSerine/threonine-protein kinase B-raftarget
DB08896RegorafenibCytochrome P450 2C8enzyme
DB08896RegorafenibCytochrome P450 2C9enzyme
DB08896RegorafenibCytochrome P450 2B6enzyme
DB08896RegorafenibMitogen-activated protein kinase 11target
DB08896RegorafenibTyrosine-protein kinase FRKtarget
DB08896RegorafenibTyrosine-protein kinase ABL1target
DB08896RegorafenibMultidrug resistance protein 1transporter
DB08896RegorafenibATP-binding cassette sub-family G member 2transporter
DB08896RegorafenibUDP-glucuronosyltransferase 1-1enzyme
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB08984EtofenamateThyroxine-binding globulincarrier
DB09018BromoprideD(2) dopamine receptortarget
DB09038EmpagliflozinSodium/glucose cotransporter 2target
DB09064CiprofibratePeroxisome proliferator-activated receptor alphatarget
DB09078LenvatinibVascular endothelial growth factor receptor 1target
DB09078LenvatinibVascular endothelial growth factor receptor 2target
DB09078LenvatinibVascular endothelial growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 1target
DB09078LenvatinibFibroblast growth factor receptor 2target
DB09078LenvatinibFibroblast growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 4target
DB09078LenvatinibPlatelet derived growth factor receptor alphatarget
DB09078LenvatinibMast/stem cell growth factor receptor Kittarget
DB09078LenvatinibMultidrug resistance protein 1transporter
DB09078LenvatinibATP-binding cassette sub-family G member 2transporter
DB09078LenvatinibCytochrome P450 3A4enzyme
DB09078LenvatinibAldehyde oxidaseenzyme
DB09078LenvatinibCytochrome P450 2C8enzyme
DB09078LenvatinibCytochrome P450 2C9enzyme
DB09078LenvatinibCytochrome P450 1A2enzyme
DB09078LenvatinibCytochrome P450 2B6enzyme
DB09078LenvatinibCytochrome P450 2C19enzyme
DB09078LenvatinibSolute carrier family 22 member 6transporter
DB09078LenvatinibSolute carrier family 22 member 8transporter
DB09078LenvatinibSolute carrier family 22 member 2transporter
DB09078LenvatinibSolute carrier organic anion transporter family member 1B1transporter
DB09078LenvatinibBile salt export pumptransporter
DB09078LenvatinibCytochrome P450 2D6enzyme
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB09085TetracaineRyanodine receptor 1target
DB09085TetracaineRyanodine receptor 2target
DB09085TetracaineVoltage gated sodium channeltarget
DB09088AmylocaineVoltage gated sodium channeltarget
DB09089TrimebutineMu-type opioid receptortarget
DB09089TrimebutineVoltage-dependent L-type calcium channeltarget
DB09089TrimebutineCalcium-activated potassium channeltarget
DB09089TrimebutineVoltage-dependent T-type calcium channeltarget
DB09089TrimebutineMuscarinic acetylcholine receptor M1target
DB09089TrimebutineMuscarinic acetylcholine receptor M2target
DB09089TrimebutineMuscarinic acetylcholine receptor M3target
DB09089TrimebutineMuscarinic acetylcholine receptor M4target
DB09089TrimebutineCytochrome P450 3A4enzyme
DB09120ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
DB09120ZucapsaicinCytochrome P450 1A2enzyme
DB09120ZucapsaicinCytochrome P450 2C19enzyme
DB09120ZucapsaicinCytochrome P450 2C9enzyme
DB09120ZucapsaicinCytochrome P450 2E1enzyme
DB09143SonidegibSmoothened homologtarget
DB09143SonidegibCytochrome P450 3A4enzyme
DB09148Florbetaben (18F)Cytochrome P450 2J2enzyme
DB09148Florbetaben (18F)Leukotriene-B(4) omega-hydroxylase 1enzyme
DB09148Florbetaben (18F)Amyloid beta A4 proteintarget
DB09216Tolfenamic AcidProstaglandin G/H synthase 1target
DB09216Tolfenamic AcidProstaglandin G/H synthase 2target
DB09216Tolfenamic AcidCytochrome P450 3A4enzyme
DB09235EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09235EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09235EfonidipineCytochrome P450 3A4enzyme
DB09279FimasartanType-1 angiotensin II receptortarget
DB09279FimasartanSolute carrier organic anion transporter family member 1B1transporter
DB09279FimasartanATP-binding cassette sub-family G member 2transporter
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1A9enzyme
DB09333Iopodic acidThyroxine 5-deiodinasetarget
DB09333Iopodic acidSerum albumincarrier
DB09340Tyropanoic acidBeta-glucuronidaseenzyme
DB09342PropoxycaineVoltage gated sodium channeltarget
DB09342PropoxycaineLiver carboxylesterase 1enzyme
DB09347Acetrizoic acidSerum albumincarrier
DB09526HydroquinoneSerum albumincarrier
DB11064HomosalateProgesterone receptortarget
DB11064HomosalateAndrogen receptortarget
DB11064HomosalateEstrogen receptor alphatarget
DB11071Phenyl salicylateProstaglandin G/H synthase 1target
DB11071Phenyl salicylateProstaglandin G/H synthase 2target
DB11079Trolamine salicylateProstaglandin G/H synthase 1target
DB11079Trolamine salicylateProstaglandin G/H synthase 2target
DB11085ResorcinolThyroid peroxidasetarget
DB11148ButambenVoltage-dependent calcium channeltarget
DB11148ButambenVoltage gated sodium channeltarget
DB11148ButambenAlpha-1-acid glycoprotein 1carrier
DB11148ButambenSerum albumincarrier
DB11148ButambenATP-sensitive potassium channeltarget
DB11155TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
DB11155TriclocarbanCytochrome P450 1A1enzyme
DB11155TriclocarbanCytochrome P450 1B1enzyme
DB11160PhenyltoloxamineHistamine H1 receptortarget
DB11185SulisobenzoneSkin epithelial cellstarget
DB11221DioxybenzoneSex hormone-binding globulintarget
DB11254HexylresorcinolDNA topoisomerase 1target
DB11254HexylresorcinolProtein-glutamine gamma-glutamyltransferase 2target
DB11323Glycol salicylateProstaglandin G/H synthase 1target
DB11323Glycol salicylateProstaglandin G/H synthase 2target
DB11324NonivamideTransient receptor potential cation channel subfamily V member 1target
DB11359GuaiacolSerum albumintarget
DB11478ZeranolEstrogen receptor alphatarget
DB11478ZeranolSex hormone-binding globulintarget
DB11672CurcuminPeroxisome proliferator-activated receptor gammatarget
DB11672CurcuminVitamin D3 receptortarget
DB11672CurcuminMultidrug resistance-associated protein 5target
DB11672CurcuminCarbonyl reductase [NADPH] 1target
DB11672CurcuminGlutathione S-transferase Ptarget
DB11672CurcuminCytochrome P450 2C9enzyme
DB11672CurcuminCytochrome P450 3A4enzyme
DB11672CurcuminCytochrome P450 2B6enzyme
DB11672CurcuminCytochrome P450 1A2enzyme
DB11672CurcuminCytochrome P450 2D6enzyme
DB11672CurcuminGlutathione S-transferase A1enzyme
DB11672CurcuminGlutathione S-transferase Mu 1enzyme
DB11672CurcuminGlutathione S-transferase Penzyme
DB11672CurcuminMultidrug resistance protein 1transporter
DB11703AcalabrutinibTyrosine-protein kinase BTKtarget
DB11703AcalabrutinibCytochrome P450 3A4enzyme
DB11703AcalabrutinibCytochrome P450 3A5enzyme
DB11830MocetinostatHistone deacetylase 1target
DB11830MocetinostatHistone deacetylase 3target
DB11830MocetinostatHistone deacetylase 2target
DB11831DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DB11831DinitrochlorobenzeneGlutathione S-transferase Ptarget
DB11855RevefenacinCytochrome P450 2D6enzyme
DB11855RevefenacinMuscarinic acetylcholine receptortarget
DB11855RevefenacinSerum albumincarrier
DB11855RevefenacinSolute carrier organic anion transporter family member 1B1transporter
DB11855RevefenacinSolute carrier organic anion transporter family member 1B3transporter
DB11855RevefenacinMultidrug resistance protein 1transporter
DB11855RevefenacinATP-binding cassette sub-family G member 2transporter
DB11978GlasdegibCytochrome P450 3A4enzyme
DB11978GlasdegibSmoothened homologtarget
DB11978GlasdegibCytochrome P450 2C8enzyme
DB11978GlasdegibUDP-glucuronosyltransferase 1-9enzyme
DB11978GlasdegibSerum albumincarrier
DB11978GlasdegibMultidrug resistance protein 1transporter
DB11978GlasdegibATP-binding cassette sub-family G member 2transporter
DB11978GlasdegibMultidrug and toxin extrusion protein 1transporter
DB11978GlasdegibMultidrug and toxin extrusion protein 2transporter
DB12323RadotinibTyrosine-protein kinase ABL1target
DB12364BetrixabanMultidrug resistance protein 1transporter
DB12364BetrixabanCoagulation factor Xtarget
DB12364BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
DB12371SiponimodSphingosine 1-phosphate receptor 5target
DB12371SiponimodSphingosine 1-phosphate receptor 1target
DB12371SiponimodCytochrome P450 3A4enzyme
DB12371SiponimodCytochrome P450 2C9enzyme
DB12445NitroaspirinProstaglandin G/H synthase 1target
DB12450Propyl GallateEstrogen receptor alphatarget
DB12518RacloprideD(2) dopamine receptortarget
DB12887TazemetostatHistone-lysine N-methyltransferase EZH2target
DB13025TiaprideD(2) dopamine receptortarget
DB13025TiaprideD(3) dopamine receptortarget
DB13025TiaprideSerotonin Receptorstarget
DB13025TiaprideAlpha-1 adrenergic receptorstarget
DB13025TiaprideAlpha-2 adrenergic receptorstarget
DB13154ParachlorophenolSolute carrier organic anion transporter family member 1B3transporter
DB13154ParachlorophenolSodium channel protein type 4 subunit alphatarget
DB13269Dichlorobenzyl alcoholSodium channel proteintarget
DB13346BufexamacProstaglandin G/H synthase 1target
DB13346BufexamacProstaglandin G/H synthase 2target
DB13346BufexamacHistone deacetylase 6target
DB13346BufexamacHistone deacetylase 10target
DB13757EpanololCytochrome P450 2D6enzyme
DB13873Fenofibric acidPeroxisome proliferator-activated receptor alphatarget
DB13873Fenofibric acidMetalloproteinasetarget
DB13873Fenofibric acidPeroxisome proliferator-activated receptor gammatarget
DB13873Fenofibric acidPeroxisome proliferator-activated receptor deltatarget
DB13873Fenofibric acidNuclear receptor subfamily 1 group I member 2target
DB13877IniparibPoly [ADP-ribose] polymerase 1target
DB13908AmylmetacresolVoltage gated sodium channeltarget
DB13909Bismuth subgallateSerum albumincarrier
DB13931NetarsudilRho-associated protein kinase 1target
DB13931NetarsudilRho-associated protein kinase 2target
DB13931Netarsudilsolute carrier family 6 member 2target
DB13988SB-2699705-hydroxytryptamine receptor 7target
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylatePhosphoethanolamine/phosphocholine phosphatasetarget
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 2transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB08044ABT-341Dipeptidyl peptidase 4target
DB14060NS-398Cyclooxygenase 2target
DB06422Ticalopride5-hydroxytryptamine receptor 4target
DB06422Ticalopride5-hydroxytryptamine receptor 3Atarget
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB02130Vanillic acidChorismate--pyruvate lyasetarget
DB03176KB-141Thyroid hormone receptor betatarget
DB03176KB-141Thyroid hormone receptor alphatarget
DB03523BrequinarDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB07101PD-0325901Dual specificity mitogen-activated protein kinase kinase 1target
DB07941PH-797804Mitogen-activated protein kinase 14target
DB12020TecovirimatEnvelope protein F13target
DB12020TecovirimatUDP-glucuronosyltransferase 1-1enzyme
DB12020TecovirimatUDP-glucuronosyltransferase 1-4enzyme
DB12177Eplivanserin5-hydroxytryptamine receptor 2Atarget
DB12177Eplivanserin5-hydroxytryptamine receptor 2Ctarget
DB12555Nelotanserin5-hydroxytryptamine receptor 2Atarget
DB12874QuizartinibReceptor-type tyrosine-protein kinase FLT3target
DB09298SilibininSolute carrier family 22 member 6transporter
DB09298SilibininUDP-glucuronosyltransferase 1-1enzyme
DB09298SilibininSolute carrier organic anion transporter family member 1B1transporter
DB09298SilibininSolute carrier organic anion transporter family member 1B3transporter
DB09298SilibininSolute carrier organic anion transporter family member 2B1transporter
DB09026AliskirenCytochrome P450 3A4enzyme