Human interleukin-2

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Human interleukin-2
Accession Number
DB14865
Type
Biotech
Groups
Investigational
Description

Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).

Synonyms
  • IL-2
  • INTERLEUKIN-2
Categories
UNII
FNO32LO217
CAS number
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0RecruitingTreatmentAbdominal Wall Defects / Amputation;Traumatic;Old / Face injury / Face; Deformity / Traumatic Amputations1
1Active Not RecruitingTreatmentChronic Graft Versus Host Disease / Complications of Organ Transplant Stem Cells1
1Active Not RecruitingTreatmentGraft Versus Host Disease (GVHD)1
1Active Not RecruitingTreatmentType 1 Insulin-Dependent Diabetes Mellitus1
1CompletedTreatmentAcquired Immune Deficiency Syndrome (AIDS) / Human Immunodeficiency Virus (HIV) Infections1
1CompletedTreatmentAcute Lymphoblastic Leukaemias (ALL) / Chronic Chronic myelogenous leukemia / Juvenile Myelomonocytic Leukemia / Myelodysplastic Syndrome / Non-Hodgkin's Lymphoma (NHL)1
1CompletedTreatmentAdult Soft Tissue Sarcoma / Bone Cancer / Cancer, Breast / Colorectal Cancers / Eye Cancer / Lung Cancers / Malignant Neoplasm of Colon / Melanoma / Ovarian Sarcoma / Rectal Carcinoma / Uterine Sarcoma1
1CompletedTreatmentCLDN18.2-positive Adenocarcinoma of Esophagus / CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction / CLDN18.2-positive Gastric Adenocarcinoma1
1CompletedTreatmentCancer of the Ovary / Fallopian Tube Carcinoma / Primary Peritoneal Carcinoma1
1CompletedTreatmentGastrointestinal Metastatic Cancer1
1CompletedTreatmentHodgkins Disease (HD) / Leukemias / Multiple Myeloma (MM) / Non-Hodgkin's Lymphoma (NHL) / Other Plasma Cell Dyscrasia (Waldenstrom, Amyloidosis)1
1CompletedTreatmentMelanoma1
1CompletedTreatmentNeoplasms Metastasis / Neoplasms, Breast1
1CompletedTreatmentNeuroblastomas1
1Not Yet RecruitingTreatmentCancer, Advanced / Mesothelioma, Malignant / PD-L1 negative / Progressive Disease1
1Not Yet RecruitingTreatmentSolid Tumor, Adult1
1RecruitingTreatmentAdvanced Ovarian Cancer / Malignant Melanoma1
1RecruitingTreatmentFallopian Tube Cancer / Ovarian Epithelial Cancer / Primary Peritoneal Cancer1
1RecruitingTreatmentHepatocellular,Carcinoma2
1RecruitingTreatmentMetastatic Melanoma1
1RecruitingTreatmentRecurrent, Platinum Resistant High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer1
1RecruitingTreatmentUlcerative Colitis (UC)1
1TerminatedTreatmentNeoplasms, Kidney1
1WithdrawnTreatmentChronic Lymphocytic B-Leukemia1
1WithdrawnTreatmentInvasive Bladder Cancer Stage IV1
1WithdrawnTreatmentMetastatic Renal Cell Carcinoma1
1, 2Active Not RecruitingTreatmentOvarian Cancer Metastatic1
1, 2Active Not RecruitingTreatmentRenal Cell Adenocarcinoma1
1, 2CompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections1
1, 2CompletedTreatmentMetastatic Melanoma1
1, 2Not Yet RecruitingTreatmentAdvanced Malignant Solid Tumor1
1, 2Not Yet RecruitingTreatmentRecurrent Miscarriages1
1, 2Not Yet RecruitingTreatmentStage IV Adult Hodgkin Lymphoma / Stage IV Diffuse Large B-Cell Lymphoma / Stage IV Gastric Carcinoma / Stage IV Nasopharyngeal Carcinoma / Stage IV T-Cell Lymphoma1
1, 2RecruitingTreatmentHead and Neck Squamous Cell Carcinoma (HNSCC) / Lung Cancer Non-Small Cell Cancer (NSCLC) / Metastatic Melanoma / Metastatic Renal Cell Carcinoma1
1, 2RecruitingTreatmentLeukemia, B-Cell / Lymphoma, B-Cell1
1, 2RecruitingTreatmentMacrophage Activation Syndrome1
1, 2TerminatedTreatmentBladder Cancers / Cancer, Breast / Cervical Cancers / Malignant Melanoma / Melanoma / Metastatic Cancer That Express the MAGE-A3-HLA A01 Antigen / Metastatic Cancers / Metastatic Melanoma That Express the MAGE-A3-HLA A01 Antigen / Oesophageal Carcinoma / Renal Cancers / Sarcomas / Urothelial Cancer1
1, 2Unknown StatusTreatmentAlopecia Areata (AA)1
1, 2WithdrawnTreatmentMelanoma / Renal Cell Adenocarcinoma1
2Active Not RecruitingTreatmentChronic Graft Versus Host Disease1
2Active Not RecruitingTreatmentLeukemia Acute Myeloid Leukemia (AML) / Myelodysplastic Syndrome1
2Active Not RecruitingTreatmentMalignant Melanoma1
2Active Not RecruitingTreatmentMetastatic Clear Cell Renal Cell Carcinoma1
2Active Not RecruitingTreatmentType 1 Insulin-Dependent Diabetes Mellitus1
2CompletedNot AvailableAcute Myelogenous Leukaemia (AML)1
2CompletedTreatmentCancer of the Ovary / Cancer, Breast / Fallopian Tube Cancer / Primary Peritoneal Cancer1
2CompletedTreatmentChronic Lymphocytic Leukaemia (CLL) / Non-Hodgkin's Lymphoma (NHL)1
2CompletedTreatmentEwing's Sarcoma (ES) / Rhabdomyosarcomas1
2CompletedTreatmentExtraocular Extension Melanoma / Recurrent Intraocular Melanoma1
2CompletedTreatmentHodgkins Disease (HD) / Non Hodgkin Lymphoma (NHL)1
2CompletedTreatmentHuman Immunodeficiency Virus (HIV)1
2CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections6
2CompletedTreatmentMelanoma2
2CompletedTreatmentMelanoma / Neoplasms Metastasis2
2CompletedTreatmentMetastatic Disease / Renal Cell Adenocarcinoma1
2CompletedTreatmentMyelodysplastic Syndrome1
2CompletedTreatmentRecurrent Melanoma / Stage IV Melanoma1
2CompletedTreatmentRenal Cell Adenocarcinoma1
2CompletedTreatmentSystemic Lupus Erythematosus (SLE)1
2Not Yet RecruitingTreatmentInterleukin 2 / Steroid Dependent Nephrotic Syndrome1
2Not Yet RecruitingTreatmentMetastatic Colorectal Cancers1
2Not Yet RecruitingTreatmentMetastatic Melanoma1
2RecruitingPreventionAcute Graft-Versus-Host Disease1
2RecruitingTreatmentAmyotrophic Lateral Sclerosis (ALS)1
2RecruitingTreatmentHigh Grade Ovarian Serous Adenocarcinoma / Oligometastasis / Ovarian Carcinosarcoma / Pancreatic Ductal Adenocarcinoma / Recurrent Malignant Neoplasm / Recurrent Osteosarcoma / Recurrent Ovarian Carcinoma / Refractory Malignant Neoplasm / Refractory Osteosarcoma / Refractory Ovarian Carcinoma1
2RecruitingTreatmentMalignant Melanoma Stage IV1
2RecruitingTreatmentMelanoma2
2RecruitingTreatmentMelanoma Stage Iv / Renal Cell Carcinoma, Metastatic1
2RecruitingTreatmentNewly Diagnosed High Risk Neuroblastoma1
2RecruitingTreatmentOvarian Cancer Metastatic1
2TerminatedTreatmentAcute Myelogenous Leukaemia (AML)1
2TerminatedTreatmentAcute Myelogenous Leukaemia (AML) / Refractory Acute Myelogenous Leukemia1
2TerminatedTreatmentCancer, Breast1
2TerminatedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
2TerminatedTreatmentKidney Cancer Metastatic / Renal Cell Cancer Metastatic1
2TerminatedTreatmentLeukemia, Myelogenous, Acute1
2TerminatedTreatmentMelanoma Metastatic1
2TerminatedTreatmentMetastatic Colorectal Cancers1
2TerminatedTreatmentMetastatic Renal Cell Carcinoma2
2TerminatedTreatmentNon-Hodgkin's Lymphoma (NHL)1
2TerminatedTreatmentRenal Cancers1
2TerminatedTreatmentRenal Cell Adenocarcinoma1
2WithdrawnTreatmentMelanoma / Metastatic Kidney Cancer1
3CompletedTreatmentMetastatic Renal Cell Carcinoma1
3CompletedTreatmentRenal Cell Adenocarcinoma1
3Unknown StatusPreventionHepatitis A / Human Immunodeficiency Virus (HIV) Infections / Viral Hepatitis B1
4CompletedPreventionDepression1
4CompletedTreatmentHepatitis B Chronic Infection1
Not AvailableActive Not RecruitingTreatmentBeta Thalassemia Major1
Not AvailableCompletedPreventionSystemic Lupus Erythematosus (SLE)1
Not AvailableCompletedTreatmentSystemic Lupus Erythematosus (SLE)1
Not AvailableTerminatedPreventionLeukemias1
Not AvailableWithdrawnNot AvailableHormone Refractory Prostate Cancer1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:31 / Updated on May 21, 2019 12:30