Analgesics, Non-Narcotic

Name
Analgesics, Non-Narcotic
Accession Number
DBCAT000040
Description

A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS.

Drugs
DrugDrug Description
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
AdapaleneA topical retinoid agent used for the treatment of acne vulgaris.
MesalazineAn aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
PimecrolimusA topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
CarbamoylcholineA direct acting miotic agent administered ophthalmically to decrease intraocular pressure in glaucoma or after eye surgery, and to induce miosis during surgery.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
ErgotamineA alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
CastanospermineNot Available
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
PhenacetinUsed principally as an analgesic.
Niflumic acidUsed in the treatment of rheumatoid arthritis.
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
BenoxaprofenThe use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
MetamizoleUsed in the past as a powerful painkiller and fever reducer.
ZomepiracZomepirac was indicated for the management of mild to severe pain.
PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
Samarium (153Sm) lexidronamA chelated complex of samarium isotope and EDTMP that concentrates in areas with high bone turnover such as sites of metastases to relieve pain associated with osteoblastic metastatic bone lesions.
AndrographolideInvestigated for use/treatment in ulcerative colitis.
PizotifenA serotonin and tryptamine antagonist indicated for migraine prophylaxis.
IcatibantA bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE).
ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
Nitrous oxideAn inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure.
LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
ZaltoprofenA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
SeratrodastSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
AzapropazoneNot Available
FelbinacNot Available
TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
EpibatidineNot Available
Ferulic acidNot Available
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
KebuzoneKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
IsoxicamIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EtofenamateEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
EpirizoleEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
LoxoprofenLoxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders. In addition to its effects on pain, it is an antipyretic and anti-inflammatory...
DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
ClonixinIndicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
MedetomidineMedetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist....
TepoxalinTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...
FlunixinFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form....
CurcuminNo approved therapeutic indications.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
SemapimodSemapimod has been used in trials studying the treatment of Crohn Disease.
BucillamineBucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
NefopamNefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
LisofyllineLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
IndobufenIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
ApocyninAcetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
HigenamineHigenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).
TinoridineTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
ParthenolideParthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.
SerrapeptaseSerrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections. Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet)...
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
FentiazacNot Annotated
TribenosideAnti-inflammatory agent used in edema of extremities, varicose veins & phlebitis.
SuxibuzoneNot Annotated
BumadizoneBumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
AlminoprofenAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
FlunoxaprofenNot Annotated
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
FeprazoneNot Annotated
DifenpiramideNot Annotated
NifenazoneNot Annotated
LonazolacNot Annotated
TenidapNot Annotated
BendazacPrior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the...
PranoprofenNot Annotated
PropyphenazoneNot Annotated
ProglumetacinNot Annotated
GuacetisalNot Annotated
BevoniumNot Annotated
EthenzamideNot Annotated
Carbaspirin calciumNot Annotated
MofebutazoneNot Annotated
ProquazoneNot Annotated
BenorilateNot Annotated
PirprofenNot Annotated
AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation...
DixyrazineNot Annotated
Imidazole salicylateNot Annotated
Thiosalicylic acidNot Annotated
PalmidrolA cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food...
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
TaxifolinNot Available
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
EbselenEbselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Human interleukin-2Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Flurbiprofen axetilFlurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
LicofeloneFor the management of osteoarthritis.
MilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
EcallantideA kallikrein inhibitor used to prevent and treat acute attacks caused by Hereditary Angioedema (HAE).
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
FasinumabFasinumab has been used in trials studying the basic science and treatment of Sciatica, Back Pain, Low Back Pain, Osteoarthritis, Hip, and Abdominal Pain Upper, among others.
DextromethadoneDextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).
Ursolic acidNot Annotated
Drugs & Drug Targets
DrugTargetType
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
AdapaleneRetinoic acid receptor alphatarget
AdapaleneRetinoic acid receptor RXR-betatarget
AdapaleneRetinoic acid receptor gammatarget
AdapaleneRetinoic acid receptor betatarget
AdapaleneRetinoic acid receptor RXR-gammatarget
AdapaleneRetinoic acid receptor RXR-alphatarget
AdapaleneProstaglandin G/H synthase 2target
MesalazineProstaglandin G/H synthase 1target
MesalazineProstaglandin G/H synthase 2target
MesalazinePeroxisome proliferator-activated receptor gammatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
MesalazineArachidonate 5-lipoxygenasetarget
MesalazineMyeloperoxidasetarget
MesalazineArylamine N-acetyltransferasetarget
MesalazineArylamine N-acetyltransferase 1enzyme
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenP-glycoprotein 1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3/1A4enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenSerum albumincarrier
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DihydroergotamineCytochrome P450 3A4enzyme
DihydroergotamineAlpha-2A adrenergic receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DihydroergotamineP-glycoprotein 1transporter
AmitriptylineSodium-dependent serotonin transportertarget
AmitriptylineSodium-dependent noradrenaline transportertarget
AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
AmitriptylineAlpha-2A adrenergic receptortarget
AmitriptylineCytochrome P450 1A2enzyme
AmitriptylineCytochrome P450 2C19enzyme
AmitriptylineCytochrome P450 2D6enzyme
AmitriptylineSerum albumincarrier
AmitriptylineAlpha-1-acid glycoprotein 1carrier
AmitriptylineHistamine H1 receptortarget
Amitriptyline5-hydroxytryptamine receptor 2Atarget
Amitriptyline5-hydroxytryptamine receptor 1Atarget
AmitriptylineAlpha-1A adrenergic receptortarget
AmitriptylineCytochrome P450 3A4enzyme
AmitriptylineCytochrome P450 3A5enzyme
AmitriptylinePotassium voltage-gated channel subfamily A member 1target
AmitriptylineAlpha-1D adrenergic receptortarget
AmitriptylineDelta-type opioid receptortarget
AmitriptylineKappa-type opioid receptortarget
AmitriptylineHigh affinity nerve growth factor receptortarget
AmitriptylineBDNF/NT-3 growth factors receptortarget
AmitriptylineCytochrome P450 2C9enzyme
AmitriptylineCytochrome P450 2B6enzyme
AmitriptylineCytochrome P450 2C8enzyme
AmitriptylineHistamine H2 receptortarget
AmitriptylineHistamine H4 receptortarget
AmitriptylineSigma non-opioid intracellular receptor 1target
Amitriptyline5-hydroxytryptamine receptor 2Ctarget
AmitriptylineAlpha-1B adrenergic receptortarget
Amitriptyline5-hydroxytryptamine receptor 7target
Amitriptyline5-hydroxytryptamine receptor 1Dtarget
AmitriptylineMu-type opioid receptortarget
Amitriptyline5-hydroxytryptamine receptor 1Btarget
Amitriptyline5-hydroxytryptamine receptor 6target
AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
Amitriptyline5-hydroxytryptamine receptor 1Ctarget
AmitriptylineMuscarinic acetylcholine receptortarget
AmitriptylineHERG human cardiac K+ channeltarget
AmitriptylineP-glycoprotein 1transporter
AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
PimecrolimusSerine/threonine-protein kinase mTORtarget
PimecrolimusCytochrome P450 3A4enzyme
CarbamoylcholineMuscarinic acetylcholine receptor M1target
CarbamoylcholineMuscarinic acetylcholine receptor M2target
CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
CarbamoylcholineCytosolic phospholipase A2enzyme
CarbamoylcholineAcetylcholinesterasetarget
CarbamoylcholineMuscarinic acetylcholine receptor M3target
CarbamoylcholineMuscarinic acetylcholine receptor M4target
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
KetorolacProstaglandin G/H synthase 1target
KetorolacProstaglandin G/H synthase 2target
KetorolacUDP-glucuronosyltransferase 2B7enzyme
KetorolacCytochrome P450 2C8enzyme
KetorolacCytochrome P450 2C9enzyme
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
DronabinolCannabinoid receptor 1target
DronabinolCytochrome P450 3A4enzyme
DronabinolCytochrome P450 2C9enzyme
DronabinolCannabinoid receptor 2target
DronabinolP-glycoprotein 1transporter
DronabinolATP-binding cassette sub-family G member 2transporter
DronabinolProstaglandin G/H synthase 1enzyme
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinSerum albumincarrier
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
SulindacProstaglandin G/H synthase 2target
SulindacAldose reductasetarget
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacSerum albumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
ChloroquineTumor necrosis factortarget
ChloroquineToll-like receptor 9target
ChloroquineGlutathione S-transferase A2target
ChloroquineCytochrome P450 2D6enzyme
ChloroquineCytochrome P450 3A4enzyme
ChloroquineCytochrome P450 1A1enzyme
ChloroquineCytochrome P450 2C8enzyme
ChloroquineCytochrome P450 3A5enzyme
ChloroquineGlutathione S-transferasetarget
ChloroquineP-glycoprotein 1transporter
ChloroquineSerum albumincarrier
Chloroquinealpha1-acid glycoproteincarrier
ChloroquineHigh mobility group protein B1target
ChloroquineGlutathione S-transferase Mu 1target
ChloroquineAngiotensin-converting enzyme 2target
DexmedetomidineAlpha-2A adrenergic receptortarget
DexmedetomidineCytochrome P450 2E1enzyme
DexmedetomidineCytochrome P450 1A2enzyme
DexmedetomidineCytochrome P450 1A1enzyme
DexmedetomidineCytochrome P450 2D6enzyme
ErgotamineAlpha-1A adrenergic receptortarget
Ergotamine5-hydroxytryptamine receptor 1Dtarget
Ergotamine5-hydroxytryptamine receptor 1Btarget
Ergotamine5-hydroxytryptamine receptor 2Atarget
ErgotamineAlpha-2A adrenergic receptortarget
ErgotamineDopamine D2 receptortarget
ErgotamineAlpha-2B adrenergic receptortarget
ErgotamineSodium-dependent noradrenaline transportertarget
ErgotamineCytochrome P450 3A4enzyme
ErgotamineAlpha-1B adrenergic receptortarget
ErgotamineAlpha-1D adrenergic receptortarget
ErgotamineP-glycoprotein 1transporter
ErgotamineD(1) dopamine receptortarget
Ergotamine5-hydroxytryptamine receptor 1Atarget
Ergotamine5-hydroxytryptamine receptor 1Ftarget
Ergotamine5-hydroxytryptamine receptor 2Ctarget
Ergotamine5-hydroxytryptamine receptor 2Btarget
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenSerum albumincarrier
FlurbiprofenMultidrug resistance-associated protein 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1-9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacSerum albumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1-3enzyme
EtodolacUDP-glucuronosyltransferase 1-10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneSolute carrier family 22 member 8transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
MeloxicamProstaglandin G/H synthase 2target
MeloxicamCytochrome P450 2C9enzyme
MeloxicamProstaglandin G/H synthase 1target
MeloxicamCytochrome P450 3A4enzyme
MeloxicamMultidrug resistance-associated protein 4transporter
Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MeloxicamCytochrome P450 2C8enzyme
MeloxicamSerum albumincarrier
MeloxicamHuman vesicular glutamate transporterstransporter
CarprofenProstaglandin G/H synthase 2target
CarprofenProstaglandin G/H synthase 1target
CarprofenSolute carrier family 22 member 6transporter
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
BromfenacProstaglandin G/H synthase 1target
BromfenacProstaglandin G/H synthase 2target
BromfenacProstaglandin G/H synthase 2enzyme
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
CastanospermineGlucan 1,3-beta-glucosidasetarget
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneSerum albumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
MetamizoleProstaglandin G/H synthase 1target
MetamizoleCytochrome P450 2B6enzyme
MetamizoleCytochrome P450 3A4enzyme
ZomepiracProstaglandin D2 receptor 2target
ZomepiracCytochrome P450 3A4enzyme
ZomepiracSerum albumincarrier
PirfenidoneFurintarget
PirfenidoneCytochrome P450 1A2enzyme
AndrographolideTumor necrosis factortarget
AndrographolideInterleukin-1 betatarget
AndrographolideInterleukin-6target
AndrographolideNuclear factor NF-kappa-B p100 subunittarget
AndrographolideNuclear factor NF-kappa-B p105 subunittarget
PizotifenMuscarinic acetylcholine receptor M2target
PizotifenMuscarinic acetylcholine receptor M1target
PizotifenMuscarinic acetylcholine receptor M3target
Pizotifen5-hydroxytryptamine receptor 2Atarget
Pizotifen5-hydroxytryptamine receptor 2Btarget
Pizotifen5-hydroxytryptamine receptor 2Ctarget
PizotifenHistamine H1 receptortarget
Pizotifen5-hydroxytryptamine receptor 1Atarget
Pizotifen5-hydroxytryptamine receptor 1Btarget
Pizotifen5-hydroxytryptamine receptor 1Dtarget
PizotifenAlpha-1A adrenergic receptortarget
PizotifenAlpha-1B adrenergic receptortarget
PizotifenAlpha-1D adrenergic receptortarget
PizotifenAlpha-2A adrenergic receptortarget
PizotifenAlpha-2B adrenergic receptortarget
PizotifenAlpha-2C adrenergic receptortarget
PizotifenUDP-glucuronosyltransferase 2B10enzyme
IcatibantB2 bradykinin receptortarget
IcatibantAminopeptidase Ntarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
ExisulindcGMP-specific 3',5'-cyclic phosphodiesterasetarget
ExisulindcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
ExisulindGlutathione S-transferase Ptarget
ExisulindAldose reductasetarget
ExisulindAldo-keto reductase family 1 member B10target
ZiconotideCytochrome P450 3A4enzyme
LornoxicamCytochrome P450 2C9enzyme
LornoxicamProstaglandin G/H synthase 1target
LornoxicamProstaglandin G/H synthase 2target
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
ZaltoprofenUDP-glucuronosyltransferase 2B7enzyme
ZaltoprofenCytochrome P450 2C9enzyme
ZaltoprofenProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2C9enzyme
SeratrodastCytochrome P450 3A4enzyme
SeratrodastCytochrome P450 2C8enzyme
SeratrodastCytochrome P450 2C19enzyme
SeratrodastCytochrome P450 2B6enzyme
SeratrodastUDP-glucuronosyltransferase 1-9enzyme
SeratrodastProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2A6enzyme
SeratrodastThromboxane A2 receptortarget
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
AzapropazoneSerum albumincarrier
FelbinacCathepsin L1target
TranilastHematopoietic prostaglandin D synthasetarget
TranilastCytochrome P450 3A4enzyme
TranilastCytochrome P450 2C9enzyme
EpibatidineCHRNA7-FAM7A fusion proteintarget
EpibatidineNeuronal acetylcholine receptor subunit alpha-7target
EpibatidineNeuronal acetylcholine receptor subunit beta-2target
EpibatidineNeuronal acetylcholine receptor subunit alpha-2target
EpibatidineNeuronal acetylcholine receptor subunit alpha-3target
EpibatidineNeuronal acetylcholine receptor subunit alpha-4target
EpibatidineNeuronal acetylcholine receptor subunit beta-4target
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
ParecoxibLactotransferrintarget
ParecoxibProstaglandin G/H synthase 2target
ParecoxibCytochrome P450 3A4enzyme
ParecoxibCytochrome P450 2C9enzyme
TeriflunomideATP-binding cassette sub-family G member 2transporter
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideCytochrome P450 2C8enzyme
TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
TeriflunomideCytochrome P450 1A2enzyme
EtofenamateThyroxine-binding globulincarrier
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
DroxicamProstaglandin G/H synthase 1target
DroxicamProstaglandin G/H synthase 2target
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
AnisodamineCytochrome P450 2D6enzyme
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
LisofyllineCytochrome P450 1A2enzyme
NitroaspirinProstaglandin G/H synthase 1target
NafamostatIntercellular adhesion molecule 1target
NafamostatTrypsin-1target
NafamostatKallikrein-1target
NafamostatProthrombintarget
NafamostatCoagulation factor Xtarget
NafamostatCoagulation factor XIItarget
NafamostatSolute carrier family 22 member 1transporter
NafamostatSolute carrier family 22 member 2transporter
AlclofenacProstaglandin G/H synthase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
NS-398Cyclooxygenase 2target
EbselenBifunctional epoxide hydrolase 2target
LicofeloneArachidonate 5-lipoxygenasetarget
LicofeloneProstaglandin G/H synthase 2target
LicofeloneGroup IIE secretory phospholipase A2target
LicofeloneCytochrome P450 2C9enzyme
LicofeloneCytochrome P450 2C8enzyme
LicofeloneCytochrome P450 2J2enzyme
LicofeloneUDP-glucuronosyltransferase 1-3enzyme
MilnacipranSodium-dependent serotonin transportertarget
MilnacipranSodium-dependent noradrenaline transportertarget
MilnacipranNMDA receptortarget
MilnacipranCytochrome P450 3A4enzyme
EcallantidePlasma kallikreintarget
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme