Infective Endocarditis

Also known as: Endocarditis infective / Infective endocarditis / Infective Endocarditides / Endocarditis / Endocarditis NOS / Endocarditis, Bacterial / Endocarditis bacterial NOS / Bacterial endocarditis / Endocarditis bacterial

DrugDrug NameDrug Description
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB01327CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
DB01211ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
DB01190ClindamycinAn antibiotic used to treat serious infections caused by susceptible anaerobic bacteria, such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, and dental infections.
DB09324SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
DrugDrug NameTargetType
DB01060AmoxicillinPenicillin-binding protein 1Atarget
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinP-glycoprotein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinBile salt export pumptransporter
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S ribosomal RNAtarget
DB09324SulbactamBeta-lactamasetarget
DrugDrug NamePhaseStatusCount
DB00080Daptomycin2Terminated1
DB00512Vancomycin2Terminated1
DB01060Amoxicillin3Recruiting1
DB01137Levofloxacin3Recruiting1
DB01045Rifampicin3Recruiting1
DB00080Daptomycin4Terminated1
DB00828Fosfomycin4Completed1
DB00798Gentamicin4Terminated1
DB01598Imipenem4Completed1
DB00512Vancomycin4Completed1
DB00080DaptomycinNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableRecruiting1
DB00512VancomycinNot AvailableCompleted1
DB00512VancomycinNot AvailableNot Yet Recruiting1