Paroxysmal Nocturnal Haemoglobinuria (PNH)

Also known as: Paroxysmal Nocturnal Hemoglobinuria (PNH) / Paroxysmal Nocturnal Hemoglobinuria / Paroxysmal Nocturnal Haemoglobinuria / Hemoglobinuria-hemol. / Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

DrugDrug NameDrug Description
DB01257EculizumabA recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
DrugDrug NameTargetType
DB01257EculizumabComplement C5target
DrugDrug NamePhaseStatusCount
DB11752Bryostatin 11Completed1
DB00020Sargramostim1Completed1
DB11580Ravulizumab1 / 2Active Not Recruiting1
DB00087Alemtuzumab2Completed1
DB00531Cyclophosphamide2Recruiting1
DB00091Cyclosporine2Active Not Recruiting2
DB00091Cyclosporine2Completed1
DB01257Eculizumab2Active Not Recruiting1
DB01257Eculizumab2Completed2
DB01073Fludarabine2Completed2
DB01073Fludarabine2Recruiting1
DB00848Levamisole2Active Not Recruiting2
DB01042Melphalan2Completed1
DB00563Methotrexate2Completed1
DB00688Mycophenolate mofetil2Completed2
DB14991Nomacopan2Completed1
DB14991Nomacopan2Recruiting1
DB15218Pozelimab2Active Not Recruiting1
DB11580Ravulizumab2Active Not Recruiting1
DB00864Tacrolimus2Completed1
DB11926Tesidolumab2Active Not Recruiting1
DB15636Zilucoplan2Active Not Recruiting1
DB15636Zilucoplan2Completed2
DB01257Eculizumab3Active Not Recruiting3
DB01257Eculizumab3Not Yet Recruiting2
DB01257Eculizumab3Recruiting3
DB14991Nomacopan3Recruiting1
DB15218Pozelimab3Enrolling by Invitation1
DB11580Ravulizumab3Active Not Recruiting2
DB11580Ravulizumab3Recruiting1
DB01257Eculizumab4Not Yet Recruiting1
DB11580Ravulizumab4Not Yet Recruiting1
DB00877Sirolimus4Not Yet Recruiting1
DB00682Warfarin4Not Yet Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableActive Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableActive Not Recruiting1
DB01073FludarabineNot AvailableActive Not Recruiting1
DB01042MelphalanNot AvailableActive Not Recruiting1