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Displaying drugs 51 - 75 of 465 in total

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn

Potassium

Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved

N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Synonyms: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) cation …
Matched Name: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) …
Matched Description: … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties ... compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate. ... chance for systemic absorption and exposure, although the formal mechanism of action of quaternary ammonium …
Matched Salts name: … N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14) …

Potassium cation

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … potassium(I) cation …
Matched Name: … Potassium cation …
Matched Description: … Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside …

Ammonium chloride

Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Approved
Investigational
Vet approved
Matched Synonyms: … Ammonium chloride …
Matched Name: … Ammonium chloride …
Matched Iupac: … ammonium chloride …
Matched Description: … Ammonium chloride is an inorganic compound with the formula NH4Cl. …
Matched Categories: … Ammonium Compounds ... ammonium chloride ... ammonium chloride …
Matched Products: … Ammonium Chloride …

Ferric ammonium citrate

Approved
Experimental
Matched Synonyms: … Ferric ammonium citrate ... Ferric ammonium citrate, green …
Matched Name: … Ferric ammonium citrate …
Matched Categories: … Ammonium Compounds ... ferric ammonium citrate …

Gentian violet cation

A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Synonyms: … Gentian violet cation …
Matched Name: … Gentian violet cation …

Ferric cation

Iron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport . Resulting from inadequate...
Approved
Matched Name: … Ferric cation …
Matched Description: … Iron exists in two oxidation states: the ferrous cation (Fe2+) and ferric cation (Fe3+). ... mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation …
Matched Categories: … Polyvalent cation containing laxatives, antacids, oral supplements …

Diphemanil

Approved
Vet approved
Withdrawn
Matched Synonyms: … Diphemanil cation …
Matched Categories: … Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Edrophonium

A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … Edrophonium cation ... Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium …
Matched Categories: … Quaternary Ammonium Compounds …

Dioctyldimonium

Approved
Experimental
Matched Synonyms: … Dioctyldimonium cation …
Matched Categories: … Ammonium Compounds …

Cetrimonium

Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Approved
Matched Synonyms: … Cetyl-Trimethyl-Ammonium ... Cetrimonium cation ... Cetyltrimethylammonium cation …
Matched Description: … Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics. …
Matched Categories: … Trimethyl Ammonium Compounds ... Quaternary Ammonium Compounds …

Choline

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Approved
Nutraceutical
Matched Synonyms: … N,N,N-trimethylethanol-ammonium …
Matched Categories: … Trimethyl Ammonium Compounds ... Quaternary Ammonium Compounds …

Ichthammol

Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed by sulfonation and neutralization. It is available in OTC products as an active ingredient for the treatment of skin disorders...
Approved
Matched Synonyms: … Ammonium bituminosulfonate ... Ammonium bituminosulphonate ... Ammonium sulphoichthyolate …
Matched Description: … Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. ... It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of …
Matched Categories: … Ammonium Compounds …

Domiphen

Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Approved
Experimental
Matched Synonyms: … Domiphen cation ... Dodecyldimethyl(2-phenoxyethyl)ammonium …
Matched Description: … Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered …
Matched Categories: … Ammonium Compounds …

Glycopyrronium

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Synonyms: … Glycopyrrolate cation ... Glycopyrronium cation …
Matched Description: … [L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists. …
Matched Categories: … Ammonium Compounds ... Quaternary Ammonium Compounds ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Vecuronium

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Synonyms: … Vecuronium cation …

Pyridostigmine

Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and fatigue. Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the...
Approved
Investigational
Matched Synonyms: … Pyridostigmine cation …

Oxyphenonium

A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]
Approved
Matched Synonyms: … Oxyphenonium cation …
Matched Description: … A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine …
Matched Categories: … Quaternary Ammonium Compounds ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Demecarium

Demecarium is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase. Cholinesterase inhibitors prolong the effect of acetylcholine, which is released at the neuroeffector junction of parasympathetic postganglion nerves, by inactivating the cholinesterases that break it down. Demecarium inactivates both pseudocholinesterase...
Approved
Matched Synonyms: … Demecarium cation …
Matched Categories: … Ammonium Compounds …

Methantheline

Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Synonyms: … Methantheline cation …
Matched Categories: … Quaternary Ammonium Compounds ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Ipratropium

Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Synonyms: … Ipratropium cation …
Matched Description: … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic …

Dequalinium

Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Description: … [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with …
Displaying drugs 51 - 75 of 465 in total