Displaying drugs 76 - 100 of 559 in total
Ledipasvir
Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … Lack of significant side effects and short duration of therapy is a considerable advantage over older interferon …
Ombitasvir
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … Lack of significant side effects and short duration of therapy is a considerable advantage over older interferon-based …
Interferon beta-1b
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta-1b ... Interferon-beta-1b ... Interferon beta 1b (recombinant) …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Interferon-beta ... Interferon Type I ... interferon beta-1b ... Recombinant Human Interferon beta …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Interferon-beta ... Interferon Type I ... interferon beta-1b ... Recombinant Human Interferon beta …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon α-2b ... Interferon alpha-2B …
Matched Name: … Interferon alfa-2b …
Matched Description: … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Interferon Type I ... interferon alfa-2b …
Matched Name: … Interferon alfa-2b …
Matched Description: … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Interferon Type I ... interferon alfa-2b …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Interferon alfa-2a ... Interferon-alfa-2a ... Interferon alpha-2a …
Matched Name: … Interferon alfa-2a …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Interferon Type I ... interferon alfa-2a …
Matched Name: … Interferon alfa-2a …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Interferon Type I ... interferon alfa-2a …
gamma-Aminobutyric acid
The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … gamma-Aminobutyric acid …
Matched Name: … gamma-Aminobutyric acid …
Matched Salts name: … Gamma-Aminobutyric Acid Hydrochloride …
Matched Name: … gamma-Aminobutyric acid …
Matched Salts name: … Gamma-Aminobutyric Acid Hydrochloride …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta 1-a ... Interferon beta 1a ... Interferon beta-1a …
Matched Name: … Interferon beta-1a …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Interferon-beta ... Interferon Type I ... interferon beta-1a ... Recombinant Human Interferon beta …
Matched Products: … AVONEX®INTERFERON BETA-1A JERINGA PRELLENADA …
Matched Name: … Interferon beta-1a …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Interferon-beta ... Interferon Type I ... interferon beta-1a ... Recombinant Human Interferon beta …
Matched Products: … AVONEX®INTERFERON BETA-1A JERINGA PRELLENADA …
Interferon alfacon-1
Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Matched Synonyms: … Interferon alfacon-1 …
Matched Name: … Interferon alfacon-1 …
Matched Description: … Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. ... Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison ... with interferon-beta shows identity at over 30% of the amino acid positions. …
Matched Categories: … Interferon alpha ... Interferon Type I ... interferon alfacon-1 …
Matched Name: … Interferon alfacon-1 …
Matched Description: … Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. ... Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison ... with interferon-beta shows identity at over 30% of the amino acid positions. …
Matched Categories: … Interferon alpha ... Interferon Type I ... interferon alfacon-1 …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … gamma-Hydroxybutyrate …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple …
Lindane
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Synonyms: … gamma-BHC ... gamma-HCH ... gamma-Lindane …
Matched Products: … Gamma Benzene Hexachloride Lotion USP 1% w/v (LICSCAB Lotion) …
Matched Products: … Gamma Benzene Hexachloride Lotion USP 1% w/v (LICSCAB Lotion) …
Vigabatrin
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … gamma-Vinyl-gamma-aminobutyric acid ... Gamma vinyl GABA ... gamma-Vinyl GABA …
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in …
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon …
Matched Description: … is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(p-Chlorophenyl)-gamma-aminobutyric acid ... gamma-Amino-beta-(p-chlorophenyl)butyric acid …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. …
Matched Categories: … gamma-Aminobutyric Acid-ergic Agonist …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. …
Matched Categories: … gamma-Aminobutyric Acid-ergic Agonist …
Coagulation Factor IX (Recombinant)
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … nonacog gamma …
Fenbufen
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … gamma-oxo(1,1'-biphenyl)-4-butanoic acid …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Follitropin gamma …
Liothyronine
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Products: … Trijodthyronin "Sandoz" 25 Gamma - Tabletten …
Emapalumab
Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018.[A38676, L4840] The approval of emapalumab was followed by the designation of orphan drug, priority review and breakthrough...
Approved
Investigational
Matched Description: … Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma …
Matched Categories: … Interferon-gamma ... Interferon gamma Blocker ... Interferon gamma Antagonists …
Matched Categories: … Interferon-gamma ... Interferon gamma Blocker ... Interferon gamma Antagonists …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Bleomycin
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Mitomycin
Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Pimecrolimus
Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Approved
Investigational
Vitamin E
In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Gamma Oil …
Cyclosporine
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Displaying drugs 76 - 100 of 559 in total