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Displaying drugs 101 - 125 of 897 in total
Darifenacin
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically...
Approved
Investigational
Matched Synonyms: … (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. ... This block reduces the urgency to urinate and so it should not be used in people with urinary retention …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. ... This block reduces the urgency to urinate and so it should not be used in people with urinary retention …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Filgrastim
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … [L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from ... Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor ( ... [L40719] It has a number of therapeutic uses, including the management and prevention of infections and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … NIVESTIM 12 MIO E/0.2ML ... NIVESTIM 12 MIO.E/0.2ML ... ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … NIVESTIM 12 MIO E/0.2ML ... NIVESTIM 12 MIO.E/0.2ML ... ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML …
Lacosamide
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Synonyms: … (R)-LACOSAMIDE 1 …
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved ... Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated …
Matched Products: … Lacosamid 1A Pharma 50 mg – Filmtabletten ... Lacosamid 1A Pharma 100 mg – Filmtabletten ... Lacosamid 1A Pharma 150 mg – Filmtabletten …
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved ... Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated …
Matched Products: … Lacosamid 1A Pharma 50 mg – Filmtabletten ... Lacosamid 1A Pharma 100 mg – Filmtabletten ... Lacosamid 1A Pharma 150 mg – Filmtabletten …
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Categories: … Artemisinin and derivatives ... artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …
Matched Categories: … Artemisinin and derivatives ... artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …
Isotretinoin
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … Neovitamin A acid ... 13-cis-Vitamin A acid …
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. ... [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. ... [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under …
Matched Categories: … Skin and Mucous Membrane Agents …
Triazolam
Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Approved
Investigational
Matched Iupac: … 12-chloro-9-(2-chlorophenyl)-3-methyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13 …
Matched Description: … Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Description: … Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Birch bark extract
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Description: … approved for the treatment of partial thickness wounds in patients with epidermolysis bullosa (EB), a ... by extreme skin fragility and blister development. ... Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities …
Prednicarbate
Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as hydrocortisone. It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a...
Approved
Investigational
Matched Description: … 1-alpha cytokine within keratinocytes. ... and IL-6 synthesis, which are related to skin thickness. ... The anti-inflammation action of corticosteroids is associated with the inhibition of the interleukin …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Isopropyl alcohol
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. ... It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … Sooth-a-Sting ... Diclo Gel 1% Pak ... B-12 Kit …
Matched Categories: … Antiseptics and Disinfectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Coghlans Survival In A Can ... A 50% ISOPROPYL Rubbing Alcohol ... Alcool Isopropylique A Friction …
Matched Mixtures name: … Sooth-a-Sting ... Diclo Gel 1% Pak ... B-12 Kit …
Matched Categories: … Antiseptics and Disinfectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Coghlans Survival In A Can ... A 50% ISOPROPYL Rubbing Alcohol ... Alcool Isopropylique A Friction …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … .DELTA.1-THC ... delta(1)-tetrahydrocannabinol ... 1-trans-delta-9-Tetrahydrocannabinol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid ... CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A (THCA-A) and ... (via the Cannabinoid Receptors CB1 and CB2) and plays a role in many physiological processes such as …
Matched Categories: … Cannabinoids and similars ... Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid ... CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A (THCA-A) and ... (via the Cannabinoid Receptors CB1 and CB2) and plays a role in many physiological processes such as …
Matched Categories: … Cannabinoids and similars ... Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Alprostadil
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … PGE-1 ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid …
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid …
Matched Description: … Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator ... intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … JECTERA 10 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET ... JECTERA 20 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET …
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid …
Matched Description: … Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator ... intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … JECTERA 10 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET ... JECTERA 20 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET …
Sucralfate
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Description: … Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal ... Sucralfate has been shown to be a well-tolerated and safe drug. ... It is sold under many brands and is available in both tablet and suspension forms. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Sucralfate-1 - Tab 1g ... ALSUCRAL POLVO 1 GRAMO ... SUCRALFATO 1 G TABLETAS …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Sucralfate-1 - Tab 1g ... ALSUCRAL POLVO 1 GRAMO ... SUCRALFATO 1 G TABLETAS …
Avacopan
Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified by the presence of ANCAs in the serum.[A240249, A240254, A227003] The full spectrum of AAV includes granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis...
Approved
Investigational
Matched Iupac: … (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl …
Matched Description: … Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence ... A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a ... fragment C5a and its cognate C5aR receptor in AAV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence ... A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a ... fragment C5a and its cognate C5aR receptor in AAV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents …
Duvelisib
Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can produce a broad adaptative and innate immune cell inhibitory activity. All the work around duvelisib showed that this agent is...
Approved
Investigational
Matched Iupac: … 8-chloro-2-phenyl-3-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-1,2-dihydroisoquinolin-1-one …
Matched Description: … that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can ... produce a broad adaptative and innate immune cell inhibitory activity. ... Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can ... produce a broad adaptative and innate immune cell inhibitory activity. ... Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Bromhexine
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased ... and reducing cough. ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … BROMHEXIN 12 BC ... MUCOLIN 1% SOLUTION …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … BROMHEXIN 12 BC ... MUCOLIN 1% SOLUTION …
Lotilaner
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Description: … Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. ... L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Scabicides, Insecticides and Repellents …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Scabicides, Insecticides and Repellents …
Tenofovir alafenamide
Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl] …
Matched Description: … L6277,L6280,L6283] and prevent HIV-1 infections. ... [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388, ... Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when …
Matched Categories: … Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Tenofovir and prodrugs ... Amino Acids, Peptides, and Proteins ... emtricitabine and tenofovir alafenamide ... emtricitabine, tenofovir alafenamide and rilpivirine …
Matched Description: … L6277,L6280,L6283] and prevent HIV-1 infections. ... [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388, ... Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when …
Matched Categories: … Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Tenofovir and prodrugs ... Amino Acids, Peptides, and Proteins ... emtricitabine and tenofovir alafenamide ... emtricitabine, tenofovir alafenamide and rilpivirine …
Oxymorphone
An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough ... 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and …
Matched Description: … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough ... 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and …
Bupropion
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Iupac: … 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one …
Matched Description: … auto-inhibition, which are associated with a reduction in food intake and increased energy expenditure ... [L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically ... Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor …
Matched Salts cas: … 905818-69-1 …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … BUPROPION 1A PHARMA 150MG ... Bupropion 1A Pharma 150 mg - Tabletten mit veränderter Wirkstofffreisetzung ... Bupropion 1A Pharma 300 mg - Tabletten mit veränderter Wirkstofffreisetzung …
Matched Description: … auto-inhibition, which are associated with a reduction in food intake and increased energy expenditure ... [L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically ... Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor …
Matched Salts cas: … 905818-69-1 …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … BUPROPION 1A PHARMA 150MG ... Bupropion 1A Pharma 150 mg - Tabletten mit veränderter Wirkstofffreisetzung ... Bupropion 1A Pharma 300 mg - Tabletten mit veränderter Wirkstofffreisetzung …
Sebelipase alfa
The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … [L39337]
Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. ... addition, patients with LAL deficiency typically develop dyslipidemia, which itself contributes to a ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [A20343, L936] A wide variety of CFTR mutations correlate to the Cystic Fibrosis phenotype and are ... Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi ... [A20298, A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs …
Matched Categories: … ivacaftor and lumacaftor ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [A20343, L936] A wide variety of CFTR mutations correlate to the Cystic Fibrosis phenotype and are ... Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi ... [A20298, A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs …
Matched Categories: … ivacaftor and lumacaftor ... Heterocyclic Compounds, 1-Ring …
Aluminum chlorohydrate
Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Description: … It is also used as a coagulant in the water purification process. ... Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl( …
Matched Mixtures name: … KURSEPT %19 + %1 KREM (30 G) …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Secret Clean Antipersp Aer 12% ... A Bille ... Lutece Creme Desodorisante A Bile 20% …
Matched Mixtures name: … KURSEPT %19 + %1 KREM (30 G) …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Secret Clean Antipersp Aer 12% ... A Bille ... Lutece Creme Desodorisante A Bile 20% …
Calcium gluconate
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate ... It can also be taken by mouth but is not recommended by injection into a muscle. ... Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Description: … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate ... It can also be taken by mouth but is not recommended by injection into a muscle. ... Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Podofilox
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Iupac: … 10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12 …
Matched Description: … It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... A lignan found in podophyllin resin from the roots of podophyllum plants. …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Description: … It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... A lignan found in podophyllin resin from the roots of podophyllum plants. …
Matched Categories: … Skin and Mucous Membrane Agents …
Hepatitis A Vaccine
Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Synonyms: … Hepatitis A vaccine, inactivated …
Matched Name: … Hepatitis A Vaccine …
Matched Description: … Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms ... [A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been ... formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection …
Matched Mixtures name: … TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR …
Matched Salts name: … Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) ... Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine …
Matched Products: … AVAXIM-SUSPENSION FOR INJ IN A PREFILLED SYRINGE ... VAQTA ® 50 U VACUNA CONTRA LA HEPATITIS A (PURIFICADA E INACTIVADA) ... Havrix (Hepatitis A-Impfstoff) 1440 El.U/ml - Injektionssuspension in einer Fertigspritze …
Matched Name: … Hepatitis A Vaccine …
Matched Description: … Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms ... [A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been ... formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection …
Matched Mixtures name: … TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR …
Matched Salts name: … Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) ... Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine …
Matched Products: … AVAXIM-SUSPENSION FOR INJ IN A PREFILLED SYRINGE ... VAQTA ® 50 U VACUNA CONTRA LA HEPATITIS A (PURIFICADA E INACTIVADA) ... Havrix (Hepatitis A-Impfstoff) 1440 El.U/ml - Injektionssuspension in einer Fertigspritze …
Displaying drugs 101 - 125 of 897 in total