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Displaying drugs 176 - 200 of 1333 in total
Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.[L13646,L13649] Unlike its other inhalational anesthetic counterparts including isoflurane and halothane, enflurane is known to induce seizure activity. In addition, it is known to cause increased cardio...
Approved
Investigational
Vet approved
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Categories: … Beta blocking agents and calcium channel blockers …
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LAMA group falls into a...
Approved
Investigational
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Categories: … Beta blocking agents and calcium channel blockers …
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line.[L12099,A191799] Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the...
Approved
Investigational
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Categories: … salbutamol and sodium cromoglicate …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Mixtures name: … Codeine Phosphate and Pseudoephedrine Hydrochloride ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Cold ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Headache …
Approved
Matched Synonyms: … Calcium phosphate dibasic, hydrous ... Calcium phosphate dihydrate, dibasic ... Dibasic calcium phosphate hydrate …
Matched Name: … Calcium phosphate dihydrate …
Matched Iupac: … calcium dihydrate hydrogen phosphate
Matched Categories: … Phosphate salts ... Calcium Compounds …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Synonyms: … Calcium acetate ... calcium ethanoate ... calcium(II) acetate …
Matched Name: … Calcium acetate …
Matched Iupac: … calcium diacetate …
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Salts name: … Calcium acetate monohydrate …
Matched Categories: … calcium acetate and magnesium carbonate ... Phosphate Binder ... Phosphate-removing Agents ... Calcium Salts ... calcium acetate …
Matched Products: … Calcium Acetate ... Calcium Acetate 667 mg ... Calcium Acetate Tab 667mg …
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Approved
Matched Synonyms: … Glubionate calcium ... Calcium glubionate anhydrous ... (D-gluconato)(lactobionato)calcium
Matched Name: … Calcium glubionate anhydrous …
Matched Description: … Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium ... levels in people who do not get enough calcium from their diets. …
Matched Salts name: … Calcium glubionate …
Matched Categories: … Calcium Salts ... calcium glubionate …
Matched Products: … CALCIUM SANDOZ %10 AMPUL, 100 ADET ... CALCIUM SANDOZ %10 AMPUL, 50 ADET ... CALCIUM SANDOZ %10 AMPUL, 5 ADET …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Synonyms: … Sodium acid phosphate ... Sodium primary phosphate ... Sodium dihydrogen phosphate
Matched Name: … Sodium phosphate, monobasic …
Matched Iupac: … sodium dihydrogen phosphate
Matched Description: … Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate
Matched Salts name: … Sodium phosphate, monobasic, dihydrate ... Sodium phosphate, monobasic, monohydrate …
Matched Categories: … sodium phosphate ... sodium phosphate ... sodium phosphate ... sodium phosphate ... Phosphate salts …
Approved
Experimental
Matched Name: … Calcium alginate …
Matched Categories: … calcium alginate …
Displaying drugs 176 - 200 of 1333 in total