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Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Synonyms: … 2-Acetoxybenzoic acid ... 2-Acetoxybenzenecarboxylic acid ... acide 2-(acétyloxy)benzoïque …
Matched Iupac: … 2-(acetyloxy)benzoic acid …
Matched Description: … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain ... Acetylsalicylic acid is a very common cause of accidental poisoning in young children. ... Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available …
Matched Salts cas: … 62952-06-1
Matched Mixtures name: … Fiorinal-C 1/2 ... Robaxisal C 1/2 ... Methoxisal-C 1/2
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … ASPIRIN N 100MG ... ASPIRIN N 300MG …
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched International brands: … Act-3
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... was in 1960 while researching for a safer alternative for aspirin. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … COX-1 Inhibitors ... COX-2 Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … PADUCAS 20 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 3 ADET ... DUKTAFEN 20 MG/2 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 3 ADET ... DISMENOL N
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain) …
Matched Description: … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant ... booster dose in patients who have previously received a COVID-19 vaccine. ... DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Synonyms: … (+) threo-2-(methylamino)-1-phenyl-1-propanol ... d-psi-2-Methylamino-1-phenyl-1-propanol …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic ... [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional …
Matched Mixtures name: … RESTAFED - H ... Calmylin #3 Syr ... Z-cof 1
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography. The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. …
Matched Salts cas: … 25387-68-2
Matched Mixtures name: … N KOUT ... DAYFLU B ... Bio-B Kids …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... คลอเฟน 2 ... AXCEL CHLORPHENIRAMINE-2 SYRUP …
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ ... 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate ... CEPHALOTAXINE 4-METHYL (2R)-2-HYDROXY-2-(4-HYDROXY-4-METHYLPENTYL)BUTANEDIOATE (ESTER) …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid ... 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] ... Pseudomonic acid A
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... Produced by fermentation using the organism _Pseudomonas fluorescens_, mupirocin is a naturally-occurring ... mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it a
Matched Mixtures name: … Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Approved
Vet approved
Matched Synonyms: … H-17-B
Matched Iupac: … ,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H …
Matched Products: … Aquax-H ... LULSADERM-H
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( ... 3,4-b)indole-1,4-dione …
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Description: … [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … N/A ... REKFİL 20 MG TABLET, 2 ADET ... LONGIVO 20 MG TABLET, 2 TABLET …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Synonyms: … influenza A virus A/Bolivia/559/2013 (H1N1) antigen
Matched Name: … Influenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Iupac: … 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine …
Matched Categories: … Hepatitis B virus ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring …
Matched Products: … HEPATOVIR-B 1 MG FILM KAPLI TABLET, 30 ADET ... HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML ... HEPATOVIR-B 0.5 MG FILM KAPLI TABLET, TABLET, 30 ADET …
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … 3'-Deoxykanamycin B ... -(1-4))-2-deoxy-D-streptamine ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a
Matched Salts cas: … 49842-07-1
Matched Mixtures name: … TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRAZON %0.3 + %0.1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … Tobramycin B. Braun 3 mg/ml Infusionslösung ... Tobramycin B. Braun 1 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Matched Salts cas: … 122852-69-1
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine ... 3-Chloroimipramine …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Synonyms: … 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol …
Matched Iupac: … 2-[2-(4-{2-thia-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin-1-yl ... )ethoxy]ethan-1-ol …
Matched Description: … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects ... It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such …
Matched Salts cas: … 111974-72-2
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … QUETIAPINA SANDOZ A/S …
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma …
Matched Salts cas: … 1256589-74-8 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro ... 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- ... 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide …
Matched Description: … Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed ... Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. ... A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL …
Matched Categories: … BCL-2 Inhibitor ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 5-Methyl-2-(1-Methylethyl)Phenol ... 2-isopropyl-5-methylphenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Description: … A phenol obtained from thyme oil or other volatile oils. ... It is used as a stabilizer in pharmaceutic preparations. ... It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Matched Products: … Influenza Care Synergy …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (b)pyrrole-2-carboxylic acid ... (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … RAMIPRIL COMP HEU 5/25MG N
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol- ... 2-yl)phenyl)urea …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ ... ]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... maintenance monotherapy resulted in a 22% reduction in the risk of death. ... demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although with a
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. ... [A6921] Ofatumumab was first approved by the FDA in 2009. ... works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) ... İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (1 ADET) ... Jemvy 20 mg/0,4 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET …
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. ... Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte ... [L42630] Belimumab was first approved by the FDA on March 9, 2011,[A251495] making it the newest drug …
Matched Categories: … Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Matched Products: … BENLYSTA 200 MG / 1 ML ... BENLYSTA SUBCUTÁNEO 200 MG / 1 ML ... BENLYSTA 400 MG IV INFUZYONLUK COZETI HAZIRLAMAK ICIN TOZ ICEREN FLAKON, 1 ADET …
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Iupac: … [15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... )-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan ... -3-yl phosphonato]oxy}propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo ... cyano[(1R,2R,3R,4R,6Z,8S,11Z,13S,14S,16Z,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl …
Matched Description: … Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name …
Matched Mixtures name: … H. Formula - Tab ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 25 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Vitamin B Complex ... Vitamin B 12, biosynthesis …
Matched Products: … CIANOCOBALAMINA - VITAMINA B-12 X 1 ML ... VITAMIN B12 RATIOPHARM N ... VITAMINA B12 1 MG/ML INYECTABLE …
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched International brands: … Clenil-A
Matched Synonyms: … (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione …
Matched Iupac: … ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate ... 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Matched Salts cas: … 77011-63-3
Matched Mixtures name: … FORMODUAL N. 200/6UG ... FORMODUAL N. 200/6UG ... CANDID-B CREAM …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
Displaying drugs 176 - 200 of 5808 in total