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Displaying drugs 201 - 225 of 10332 in total

Magnesium oxide

Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Pegloticase

Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … uric acid concentrations. ... In gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma ... [L42425] Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin …
Matched Categories: … Uric Acid-specific Enzyme ... Compounds used in a research, industrial, or household setting …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Iupac: … (2S)-2-(3-benzoylphenyl)propanoic acid …
Matched Products: … KETESSE 50mg/2ml solution for injection or concentrate for solution for infusion …

Triheptanoin

Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Description: … source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid ... [L14612] In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated …

Hyaluronidase (ovine)

Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.
Approved
Investigational

Fluorouracil

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Description: … to thymidylic acid. ... It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …

Propoxycaine

Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride . This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination...
Approved

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … provides increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets or …
Matched Mixtures name: … Strength Sensitive Soothing Mint clinically proven to reduce painful sensitivity / no artificial dyes or …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Strength Sensitive Wintermint clinically proven to reduce painful sensitivity / no artificial dyes or …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Salicylic Acid 2% /sodium Sulfacetamide Monohydrate 8% ... Salicylic Acid 2% / Sodium Sulfacetamide Monohydrate 8% ... Salicylic Acid 5% / Sodium Sulfacetamide Monohydrate 10% …

Dyclonine

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Mixtures name: … Salicylic Acid …

Hydrotalcite

Approved
Experimental
Investigational
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Bismuth subcitrate potassium

A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Categories: … Drugs for Acid Related Disorders …

Acetyl sulfisoxazole

Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … , which is the precursor of folic acid. ... ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid ... This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism ... of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. ... This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … Olipudase alfa is recombinant human acid sphingomyelinase. ... [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid …

Bismuth subnitrate

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Description: … Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Kaolin

Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate.
Approved
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …

Lactobacillus acidophilus

Approved
Experimental
Matched Categories: … Carbonic Acid …

Methantheline

Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. ... Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems ... (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents …

Aluminium phosphate

Approved
Investigational
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or ... for 12 months was superior to alendronic acid alone for 24 months[A177071]. ... menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid …

Phenelzine

Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved

Eladocagene exuparvovec

Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid …

Epinephrine

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Description: … respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity (anaphylactic or …

Trimetrexate

A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Approved
Investigational
Matched Description: … A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. …
Matched Categories: … Folic Acid Antagonists …
Displaying drugs 201 - 225 of 10332 in total