Displaying drugs 76 - 100 of 11844 in total
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide ... 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea ... 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Description: … [A183617] Glyburide was granted FDA approval on 1 May 1984. …
Matched Mixtures name: … DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 60 ADET ... İNSUCOMB 500 MG/5 MG FİLM KAPLI TABLET, 60 TABLET ... DUPLAX 500 MG/2.5 MG FILM KAPLI TABLET, 60 ADET …
Matched Products: … DIYABEN TABLET, 60 ADET ... MANINIL 1 ... MANINIL 1 BLISTER …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Description: … [A183617] Glyburide was granted FDA approval on 1 May 1984. …
Matched Mixtures name: … DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 60 ADET ... İNSUCOMB 500 MG/5 MG FİLM KAPLI TABLET, 60 TABLET ... DUPLAX 500 MG/2.5 MG FILM KAPLI TABLET, 60 ADET …
Matched Products: … DIYABEN TABLET, 60 ADET ... MANINIL 1 ... MANINIL 1 BLISTER …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Receptor-1 Blocking Antibody …
Matched Description: … (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Receptor-1 Blocking Antibody …
Mitotane
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene …
Matched Iupac: … 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene …
Matched Iupac: … 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene …
Halothane
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Synonyms: … 1-bromo-1-chloro-2,2,2-trifluoroethane ... 2,2,2-trifluoro-1-chloro-1-bromoethane …
Primaquine
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Synonyms: … 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline ... 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline ... 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid ... (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Salts cas: … 121268-17-5 …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Products: … Alendronate-5 ... ADROMAX 5 MG TABLET,28 ADET ... ADROMAX 5 MG TABLET,56 ADET …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Salts cas: … 121268-17-5 …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Products: … Alendronate-5 ... ADROMAX 5 MG TABLET,28 ADET ... ADROMAX 5 MG TABLET,56 ADET …
Palmitic Acid
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … 1-hexyldecanoic acid ... 1-Pentadecanecarboxylic acid …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … γ-(4-chlorophenyl)-γ-(2-pyridyl)propyldimethylamine ... γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML ... GRIPORT 650 MG/4 MG/ 60 MG FILM KAPLI TABLET ,20 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... ANTAMIN SYRUP 4 mg/5 ml ... ALLERSIN SYRUP 4 mg/5 ml …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML ... GRIPORT 650 MG/4 MG/ 60 MG FILM KAPLI TABLET ,20 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... ANTAMIN SYRUP 4 mg/5 ml ... ALLERSIN SYRUP 4 mg/5 ml …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide ... N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Description: … Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Description: … Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Gabapentin
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid …
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid …
Matched Mixtures name: … Innoprax-5 ... Therapentin-60 …
Matched Products: … NERUDA 250 MG/5 ML ORAL COZELTI, 470 ML ... GEMUDA 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE ... EVEPTIN 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE …
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid …
Matched Mixtures name: … Innoprax-5 ... Therapentin-60 …
Matched Products: … NERUDA 250 MG/5 ML ORAL COZELTI, 470 ML ... GEMUDA 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE ... EVEPTIN 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE …
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]- …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Salts cas: … 27164-46-1 …
Matched Mixtures name: … CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET ... CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET ... CEFAMEZIN 1000 MG IM STERİL ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET …
Matched Products: … CEFOZİN ENJEKTABL FLAKON 1 G İM/İV, 1 FLAKON + 1 AMPUL ... IESPOR IM 1 G FLAKON, 1 ADET ... IESPOR IV/IM 1 GR FLAKON, 1 ADET …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Salts cas: … 27164-46-1 …
Matched Mixtures name: … CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET ... CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET ... CEFAMEZIN 1000 MG IM STERİL ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET …
Matched Products: … CEFOZİN ENJEKTABL FLAKON 1 G İM/İV, 1 FLAKON + 1 AMPUL ... IESPOR IM 1 G FLAKON, 1 ADET ... IESPOR IV/IM 1 GR FLAKON, 1 ADET …
Ceftolozane
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Matched Synonyms: … (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino ... -1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Iupac: … ]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-4-{[(2-aminoethyl)carbamoyl]amino ... 5-amino-2-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido ... }-1-methyl-1H-pyrazol-2-ium …
Matched Mixtures name: … ZERBAXA ® 1 G/0.5 G ... ZERBAXA ® 1 G/0.5 G ... ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKON …
Matched Iupac: … ]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-4-{[(2-aminoethyl)carbamoyl]amino ... 5-amino-2-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido ... }-1-methyl-1H-pyrazol-2-ium …
Matched Mixtures name: … ZERBAXA ® 1 G/0.5 G ... ZERBAXA ® 1 G/0.5 G ... ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKON …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( …
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction …
Matched Mixtures name: … TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 5-alpha Reductase Inhibitors ... Phosphodiesterase 5 Inhibitors …
Matched Products: … DEPARTON 20 MG FILM KAPLI TABLET, 60 ADET ... PAHTAFİL 20 MG FİLM KAPLI TABLET, 60 ADET ... PUBİLTOR 20 MG FİLM KAPLI TABLET, 60 ADET …
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction …
Matched Mixtures name: … TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 5-alpha Reductase Inhibitors ... Phosphodiesterase 5 Inhibitors …
Matched Products: … DEPARTON 20 MG FILM KAPLI TABLET, 60 ADET ... PAHTAFİL 20 MG FİLM KAPLI TABLET, 60 ADET ... PUBİLTOR 20 MG FİLM KAPLI TABLET, 60 ADET …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine ... N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … RIZATRIPTAN-NEURAX 5 MG ... Maxalt 5 mg - Tabletten ... RIZATRIPTAN HEU 5 MG SMT …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … RIZATRIPTAN-NEURAX 5 MG ... Maxalt 5 mg - Tabletten ... RIZATRIPTAN HEU 5 MG SMT …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ROFLOXAN 400 MG FİLM KAPLI TABLET, 5 ADET ... EXOCİN % 0,3 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ROFLOXAN 400 MG FİLM KAPLI TABLET, 5 ADET ... EXOCİN % 0,3 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Lormetazepam
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Synonyms: … 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one ... 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Products: … LORMETAZEPAM FARMA 1 ... NOCTAMID 1 TABLETTEN …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Products: … LORMETAZEPAM FARMA 1 ... NOCTAMID 1 TABLETTEN …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [A18395] The next most common mutation, G551D, affecting 4-5% of CF patients worldwide, is characterized ... from baseline with more than 70% of patients failing to achieve an absolute improvement of at least 5% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … [A18395] The next most common mutation, G551D, affecting 4-5% of CF patients worldwide, is characterized ... from baseline with more than 70% of patients failing to achieve an absolute improvement of at least 5% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tinidazole
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Synonyms: … 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MONIDAZOL 500 MG TABLET, 4 ADET ... TINIDAZOL 1 G ... TINIDAZOL 1 G TABLETAS …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MONIDAZOL 500 MG TABLET, 4 ADET ... TINIDAZOL 1 G ... TINIDAZOL 1 G TABLETAS …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol ... 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Mixtures name: … COZAAR XQ 5/50MG TABLET ... COZAAR XQ 5/100MG TABLET ... ARAMAX® 5/100MG CAPSULAS …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Mixtures name: … COZAAR XQ 5/50MG TABLET ... COZAAR XQ 5/100MG TABLET ... ARAMAX® 5/100MG CAPSULAS …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Aminophenazone
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone ... 1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one ... 2,3-Dimethyl-4-dimethylamino-1-phenyl-5-pyrazolone …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol ... 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab …
Matched Products: … เปอร์-4 ... โมนาซีน-4 ... โปราซิน 4 …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab …
Matched Products: … เปอร์-4 ... โมนาซีน-4 ... โปราซิน 4 …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... Zepatier therapy along with ribavirin improved SVR in HCV genotype 5 patients. …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... Zepatier therapy along with ribavirin improved SVR in HCV genotype 5 patients. …
Butoconazole
Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Synonyms: … 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazole …
Matched Iupac: … 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl]-1H-imidazole …
Matched Salts cas: … 64872-77-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Gynazole-1 ... Gynazole 1 ... Gynazole.1 …
Matched Iupac: … 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl]-1H-imidazole …
Matched Salts cas: … 64872-77-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Gynazole-1 ... Gynazole 1 ... Gynazole.1 …
Aztreonam
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene ... (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino …
Matched Iupac: … -4-oxoazetidine-1-sulfonate ... (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Salts cas: … 827611-49-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZACTAM ® 1 G ... Azactam 1 g - Trockenstechampulle ... AZACTAM FOR INJECTION 1 g/vial …
Matched Iupac: … -4-oxoazetidine-1-sulfonate ... (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Salts cas: … 827611-49-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZACTAM ® 1 G ... Azactam 1 g - Trockenstechampulle ... AZACTAM FOR INJECTION 1 g/vial …
Proguanil
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
Approved
Matched Synonyms: … 1-(p-Chlorophenyl)-5-isopropylbiguanide …
Matched Iupac: … 1-[N'-(4-chlorophenyl)carbamimidamido]-N-(propan-2-yl)methanimidamide …
Matched Salts cas: … 637-32-1 …
Matched Iupac: … 1-[N'-(4-chlorophenyl)carbamimidamido]-N-(propan-2-yl)methanimidamide …
Matched Salts cas: … 637-32-1 …
Displaying drugs 76 - 100 of 11844 in total