Displaying drugs 101 - 125 of 465 in total
Technetium Tc-99m tetrofosmin
Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Description: … It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which …
Sodium zirconium cyclosilicate
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Ferrous gluconate
Approved
Matched Categories: … Polyvalent cation containing laxatives, antacids, oral supplements …
Magnesium acetate tetrahydrate
Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium is an essential element and second...
Approved
Matched Description: … Magnesium is an essential element and second most abundant cation in the body that plays a key role in …
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Potassium bicarbonate
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Choline magnesium trisalicylate
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Approved
Matched Categories: … Trimethyl Ammonium Compounds ... Quaternary Ammonium Compounds …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Zinc gluconate
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Description: … Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent …
Sevoflurane
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Sodium lauryl sulfoacetate
Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
Approved
Experimental
Calcium phosphate dihydrate
Approved
Benzoic acid
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Categories: … Ammonium Ion Binding Activity …
Crizotinib
Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT). By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers...
Approved
Investigational
Matched Categories: … Organic Cation Transporter 1 Inhibitors …
Potassium chloride
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Potassium
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.
Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Synonyms: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) cation …
Matched Name: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) …
Matched Description: … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties ... compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate. ... chance for systemic absorption and exposure, although the formal mechanism of action of quaternary ammonium …
Matched Salts name: … N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14) …
Matched Name: … N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) …
Matched Description: … N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties ... compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate. ... chance for systemic absorption and exposure, although the formal mechanism of action of quaternary ammonium …
Matched Salts name: … N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14) …
Manganese cation
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Synonyms: … MANGANOUS CATION ... MANGANESE CATION (2+) ... MANGANESE CATION (MN2+) …
Matched Name: … Manganese cation …
Matched Name: … Manganese cation …
Potassium cation
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … potassium(I) cation …
Matched Name: … Potassium cation …
Matched Description: … Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside …
Matched Name: … Potassium cation …
Matched Description: … Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside …
Gentian violet cation
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Synonyms: … Gentian violet cation …
Matched Name: … Gentian violet cation …
Matched Name: … Gentian violet cation …
Ferric cation
Iron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport . Resulting from inadequate...
Approved
Matched Name: … Ferric cation …
Matched Description: … Iron exists in two oxidation states: the ferrous cation (Fe2+) and ferric cation (Fe3+). ... mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation …
Matched Categories: … Polyvalent cation containing laxatives, antacids, oral supplements …
Matched Description: … Iron exists in two oxidation states: the ferrous cation (Fe2+) and ferric cation (Fe3+). ... mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation …
Matched Categories: … Polyvalent cation containing laxatives, antacids, oral supplements …
Displaying drugs 101 - 125 of 465 in total