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Displaying drugs 176 - 200 of 216 in total

Synthetic Conjugated Estrogens, A

Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β­ dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, and sodium 17β-estradiol sulfate. This blend of nine estrogen derivatives...
Approved
Matched Description: … sulfate, and sodium 17β-estradiol sulfate. ... sulfate and sodium equilin sulfate), they vary by their original source (such as horse-, human-, or ... sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Description: … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. ... Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension …
Matched Categories: … valsartan and aliskiren ... aliskiren and amlodipine ... aliskiren and hydrochlorothiazide ... aliskiren, amlodipine and hydrochlorothiazide …

Mycophenolic acid

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Salts name: … Mycophenolate sodium …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents …

Mesalazine

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Description: … An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine ... In the present day, contemporary research regarding novel methods to stabilize mesalazine continues and …

Ranolazine

Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant ... piperazine derivative used for the management of this condition, offering relief from uncomfortable and …
Matched Categories: … Sodium Channel Blockers …

Esterified estrogens

Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that ... It is being also for the prevention and treatment of osteoporosis. …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …

Butamben

Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben is considered to be suitable only for...
Approved
Withdrawn
Matched Description: … Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. ... [A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated …

Tauroursodeoxycholic acid

Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Description: … It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and ... [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …

Tretinoin

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Description: … activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging ... [A257474,A257629,A257609] Tretinoin is given orally to treat acute promyelocytic leukemia [L45349] and …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... OLIVIA QUIDO FIRM and FADE I ... OLIVIA QUIDO FIRM and FADE II …
Matched Categories: … Cell Stimulants and Proliferants ... Antineoplastic and Immunomodulating Agents …

Riboflavin

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ... in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. ... Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals …
Matched Salts name: … Riboflavin sodium …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Patisiran

Parisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis . It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. The approval for Onpattro...
Approved
Investigational
Matched Description: … Onpattro has been granted Fast Track, Priority Review and Breakthrough Therapy, and Orphan Drug designations …
Matched Salts name: … Patisiran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Inositol nicotinate

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and ... Niacin exists in different forms including nicotinic acid, nicotinamide and other derivatives such as ... vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and …
Matched Categories: … Nicotinic Acid and Derivatives …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Description: … for pain relief and first aid antiseptic. ... It exhibits antiseptic, anthelmintic, and local anesthetic properties. ... It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges …

Methyl nicotinate

Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Description: … muscle and joint pains [F64]. ... an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and ... methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and …

Candesartan cilexetil

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …

Fish oil

Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. More commonly, fish oil refers to the omega-3-fatty...
Approved
Nutraceutical
Matched Description: … It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... actions include inflammation modulation, cardioprotective effects, the attenuation of oxidative stress, and …
Matched Mixtures name: … Cleanse Gut And Colon …

Bovine type I collagen

Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration . Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing...
Approved
Matched Description: … skin tears) and draining wounds [L2500]. ... and effective wound healing [L2427], [L2450]. ... It plays a vital role in cell growth, differentiation, attachment, and migration [L2481]. …

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Salts name: … Rifampicin sodium …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …

Penciclovir

Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. …
Matched Salts name: … Penciclovir sodium …
Matched Categories: … Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Cerivastatin

On August 8, 2001 the U.S. Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal rhabdomyolysis, a severe adverse reaction from this cholesterol-lowering (lipid-lowering) product. It has also been withdrawn from the Canadian market.[A669,L43942]
Approved
Withdrawn
Matched Description: … Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew …
Matched Salts name: … Cerivastatin sodium …

Oleic Acid

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Approved
Investigational
Vet approved
Matched Description: … It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. ... An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. …
Matched Salts name: … Oleate sodium …

Icosapent

Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Description: … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. ... inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families. ... lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and …
Matched Salts name: … Icosapent sodium …

Carbamazepine

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … and to treat pain resulting from trigeminal neuralgia. ... Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures …
Matched Categories: … Sodium Channel Blockers …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and ... 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and ... plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and …
Matched Salts name: … Inclisiran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 176 - 200 of 216 in total