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Displaying drugs 51 - 75 of 2114 in total

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Products: … AVORAN 14 MG FİLM KAPLI TABLET, 28 ADET ... BAUDA 14 MG FİLM KAPLI TABLET , 28 ADET ... AUBAGIO 14 MG FILM KAPLI TABLET, 28 ADET …

Vildagliptin

Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Products: … GLIPTA 50 MG TABLET, 28 ADET ... DIYATIX 50 MG TABLET, 28 ADET ... TAGLİN 50 MG TABLET, 28 ADET …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Products: … ATOPRAN 20 MG FILM TABLET, 28 ADET ... ATOPRAN 40 MG FILM TABLET, 28 ADET ... LAIRA 10 MG FILM TABLET, 28 ADET …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Products: … SERDOLECT 12 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 16 MG FILM KAPLI TABLET, 28 ADET ... SERDOLECT 20 MG FILM KAPLI TABLET, 28 ADET …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Salts cas: … 78246-49-8 …
Matched Products: … PALUXON 20 MG FİLM TABLET, 28 ADET ... PALUXON 40 MG FİLM TABLET, 28 ADET ... PAXIL 20 MG FILM TABLET, 28 ADET …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Mixtures name: … INHIBACE PLUS 5 MG TABLET, 28 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Products: … INHIBACE 5 MG FİLM KAPLI TABLET, 28 ADET ... INHIBACE 2.5 MG FİLM KAPLI TABLET, 28 ADET …

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … TELVIS PLUS 80/25 TABLET, 28 ADET ... TWYNSTA 80/5 MG TABLET, 28 ADET ... TWYNSTA 80/10 MG TABLET, 28 ADET …
Matched Products: … TELPRES 80 MG TABLET, 28 ADET ... TELORA 40 MG TABLET, 28 ADET ... TELORA 80 MG TABLET, 28 ADET …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Salts cas: … 82640-04-8 …
Matched Products: … EVISTA 60 MG TABLET, 28 ADET ... ROXIMAX 60 MG FİLM TABLET, 28 ADET ... RALIEN 60 MG FILM KAPLI TABLET, 28 ADET …

Dalfampridine

Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Products: … HALFPRİN 10 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... FAMPYRA 10 MG UZATILMIŞ SALIMLI TABLET ,TABLET, 28 ADET ... Famprimes 10 mg Uzatılmış Salımlı Tablet, 28 ADET …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Products: … INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET ... INLYTA 7 MG FİLM KAPLI TABLET, 28 ADET ... INLYTA 1MG FILM KAPLI TABLET, TABLET, 28 ADET …

Aflibercept

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Products: … ZALTRAP 200 MG/8 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1ADET …

Vericiguat

Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Products: … VERQUVO 2,5 MG FİLM KAPLI TABLET , 28 ADET ... VERQUVO 5 MG FİLM KAPLI TABLET , 28 ADET ... VERQUVO 10 MG FİLM KAPLI TABLET , 28 ADET …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and FDA-approved on April 28 …
Matched Products: … ALUNBRİG 30 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 90 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 180 MG FİLM KAPLI TABLET, 28 ADET …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% …
Matched Products: … MIKODAY 500 MG TABLET, 28 ADET ... TEKFIN 250 MG TABLET, 28 ADET ... TERBIN 250 MG TABLET, 28 ADET …

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Products: … CARROX 10 MG FILM TABLET, 28 TABLET ... CARROX 20 MG FILM TABLET, 28 TABLET …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Mixtures name: … Zarah 28 ... Yasmin 28 ... Zamine 28 …
Matched Products: … ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …

Dabrafenib

Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Products: … TAFINLAR 50 MG KAPSÜL ,28 ADET ... TAFINLAR 75 MG KAPSÜL, 28 ADET …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for …
Matched Products: … YULAREB 50 MG FİLM KAPLI TABLET, 28 ADET ... YULAREB 150 MG FİLM KAPLI TABLET, 28 ADET ... YULAREB 100 MG FİLM KAPLI TABLET, 28 ADET …

Nilotinib

Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Salts cas: … 923288-90-8 …
Matched Products: … TASIGNA 150 MG KAPSUL, 28 ADET ... TASIGNA 200 MG KAPSUL, 28 ADET …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Products: … SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET ... SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Mixtures name: … QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADET …
Matched Products: … ONGLYZA 5 MG FILM KAPLI TABLET, 28 ADET ... ONGLYZA 2.5 MG FILM KAPLI TABLET, 28 ADET …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Products: … VIPIDIA 25 MG FILM KAPLI TABLET,28 ADET ... VIPIDIA 12.5 MG FILM KAPLI TABLET, 28 ADET …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8% …
Matched Mixtures name: … Sun Shade SPF 8 ... Presun 8 Creamy Lot ... Sun Protector Lotion SPF 8 …
Matched Products: … Medicated Lip Balm - Ont Top 8% …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 28 ADET ... VOSEVİ 400 MG/ 100 MG/ 100 MG FİLM KAPLI TABLET, 28 ADET …
Matched Products: … SOVALDI 400 MG FILM KAPLI TABLET, 28 ADET …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Products: … TROSYD SOLUCION PARA UÑAS 28% ... DERMO-TROSYD %28 SOLUSYON, 5 ML ... TIOCELL %28 TIRNAK SOLUSYONU, 5 CC …
Displaying drugs 51 - 75 of 2114 in total