Displaying drugs 51 - 75 of 308 in total
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Ubrogepant
Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine. Several oral small molecule CGRP receptor...
Approved
Investigational
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Sunitinib
Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Chlordiazepoxide
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Oxycodone
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Categories: … oxycodone and acetylsalicylic acid …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Posaconazole
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Trandolapril
Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Iupac: … -[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers …
Polatuzumab vedotin
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Mogamulizumab
Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically...
Approved
Investigational
Varicella zoster vaccine (recombinant)
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Description: … initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within the dorsal root …
Varicella zoster vaccine (live/attenuated)
Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within the dorsal root …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite …
Ethanol
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Products: … Root Aromatherapy Hand Sanitizer ... Cinnamon Bark Sanitizer ... Anti-Bacterial Hand Montana Mountain Air …
Octocrylene
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Mixtures name: … Root Beer SPF 15 Broad Spectrum Lip Balm ... Polyglutamic Acid Dewy Sunscreen SPF 30 ... For Men Maca Root Energetic Face Protector SPF 15 …
Birch bark extract
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Synonyms: … Betula pendula/pubescens bark …
Matched Name: … Birch bark extract …
Matched Description: … Some of the compounds identified in it include betulin, [lupeol], [betulinic acid], oleanolic acid, and ... [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species ... Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities …
Matched Name: … Birch bark extract …
Matched Description: … Some of the compounds identified in it include betulin, [lupeol], [betulinic acid], oleanolic acid, and ... [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species ... Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities …
Atractylodes lancea root oil
Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Atractyloides Japonica Root Oil …
Matched Name: … Atractylodes lancea root oil …
Matched Description: … Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Name: … Atractylodes lancea root oil …
Matched Description: … Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Stem bromelain
The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn wound eschar debridement agent that has been approved by the EMA since 2012 and marketed under the brand name Nexobrid [FDA Label].
Bromelain itself belongs to a category of protein-digesting enzymes that are...
Approved
Investigational
Matched Synonyms: … Bromelain, stem ... Pineapple stem bromelain …
Matched Name: … Stem bromelain …
Matched Description: … , the general term bromelain typically refers to stem bromelain [A27198]. ... The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn ... belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem …
Matched Name: … Stem bromelain …
Matched Description: … , the general term bromelain typically refers to stem bromelain [A27198]. ... The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn ... belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem …
Hydrogen fluoride
Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as DB00472 (Prozac). It is used as a chemical reagent in several industrial processes such as oil refinery. It is also used as etchant, cleaning agent, and a reagent to...
Approved
Investigational
Matched Synonyms: … Hydrofluoric acid ... Hydrogen fluoride, anhydrous …
Matched Name: … Hydrogen fluoride …
Matched Iupac: … hydrogen fluoride …
Matched Description: … Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Denti-Care Topical Fluoride Foam Grape ... Denti-Care Topical Fluoride Foam Raspberry …
Matched Products: … Henry Schein Topical Fluoride Cream …
Matched Name: … Hydrogen fluoride …
Matched Iupac: … hydrogen fluoride …
Matched Description: … Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Denti-Care Topical Fluoride Foam Grape ... Denti-Care Topical Fluoride Foam Raspberry …
Matched Products: … Henry Schein Topical Fluoride Cream …
Stannous fluoride
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Synonyms: … Stannous fluoride ... Tin(II) fluoride …
Matched Name: … Stannous fluoride …
Matched Description: … Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention ... Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient ... in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … stannous fluoride …
Matched Products: … Stannous Fluoride ... Home Care Fluoride ... Denti-care Stannous Fluoride …
Matched Name: … Stannous fluoride …
Matched Description: … Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention ... Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient ... in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … stannous fluoride …
Matched Products: … Stannous Fluoride ... Home Care Fluoride ... Denti-care Stannous Fluoride …
Quercus virginiana pollen
Quercus virginiana pollen is the pollen of the Quercus virginiana plant. Quercus virginiana pollen is mainly used in allergenic testing.
Approved
Matched Name: … Quercus virginiana pollen …
Matched Description: … Quercus virginiana pollen is the pollen of the Quercus virginiana plant. ... Quercus virginiana pollen is mainly used in allergenic testing. …
Matched Products: … Quercus Virginiana Pollen ... Center-AL - Quercus Virginiana Pollen …
Matched Description: … Quercus virginiana pollen is the pollen of the Quercus virginiana plant. ... Quercus virginiana pollen is mainly used in allergenic testing. …
Matched Products: … Quercus Virginiana Pollen ... Center-AL - Quercus Virginiana Pollen …
Sodium fluoride
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Synonyms: … Sodium fluoride …
Matched Name: … Sodium fluoride …
Matched Iupac: … sodium fluoride …
Matched Description: … Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications ... Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... The use of fluoride in dental practice began in the 1940s. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Multivit with Fluoride ... Multivit with Fluoride …
Matched Categories: … sodium fluoride ... sodium fluoride ... sodium fluoride, combinations …
Matched Products: … Age Defying Fluoride and Liquid Calcium ... Colgate Hemp Seed Oil ... Amino Acid Fragrancemouthwash Dawn …
Matched Name: … Sodium fluoride …
Matched Iupac: … sodium fluoride …
Matched Description: … Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications ... Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... The use of fluoride in dental practice began in the 1940s. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Multivit with Fluoride ... Multivit with Fluoride …
Matched Categories: … sodium fluoride ... sodium fluoride ... sodium fluoride, combinations …
Matched Products: … Age Defying Fluoride and Liquid Calcium ... Colgate Hemp Seed Oil ... Amino Acid Fragrancemouthwash Dawn …
Glycyrrhiza glabra
Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Gan Cao Root ... Cultivated Licorice Root ... Yashtimadhu Root …
Displaying drugs 51 - 75 of 308 in total