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Displaying drugs 76 - 100 of 11695 in total
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- ... 1-yl]- 2-oxo-ethyl]amino]acetate …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin ... -1-yl]-2-oxoethyl]amino}acetate …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin ... -1-yl]-2-oxoethyl]amino}acetate …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Synonyms: … 1-(Dimethylamino)-2-methyl-2-butanol benzoate …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Matched Salts cas: … 532-59-2 …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Matched Salts cas: … 532-59-2 …
Alfentanil
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Synonyms: … N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide …
Matched Iupac: … N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide …
Matched Products: … RAPIFEN 0,5 MG/ML 2 ML AMPUL, 5 ADET …
Matched Iupac: … N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide …
Matched Products: … RAPIFEN 0,5 MG/ML 2 ML AMPUL, 5 ADET …
Eteplirsen
Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Synonyms: … (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G ... ),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,N-dimethylphosphonamidate …
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … (2-bromobenzyl)ethyldimethylaminium ... 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium ... N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
Laurocapram
Approved
Matched Synonyms: … 1-dodecylazacycloheptan-2-one ... 1-n-dodecylazacycloheptan-2-one ... 1-dodecylhexahydro-2h-azepin-2-one …
Matched Iupac: … 1-dodecylazepan-2-one …
Matched Iupac: … 1-dodecylazepan-2-one …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} ... propane-2-sulfonamide …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Pyruvic acid
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-Oxopropansäure ... 2-Oxopropionsäure ... 2-ketopropionic acid …
Matched Iupac: … 2-oxopropanoic acid …
Matched Iupac: … 2-oxopropanoic acid …
Lormetazepam
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Synonyms: … 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one ... 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NOCTAMID 2 TABLETTEN ... Sedalor 2 mg/10 ml Injektions-/Infusionslösung …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NOCTAMID 2 TABLETTEN ... Sedalor 2 mg/10 ml Injektions-/Infusionslösung …
Nitrofural
Nitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofural has also been administered orally in the treatment of trypanosomiasis.
Except for topical drug products formulated for dermatologic application, the FDA withdrew its approval...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … 5-Nitro-2-furaldehyde semicarbazone …
Matched Iupac: … [(E)-[(5-nitrofuran-2-yl)methylidene]amino]urea …
Matched Products: … NITROCIN % 2 MERHEM, 56 G …
Matched Iupac: … [(E)-[(5-nitrofuran-2-yl)methylidene]amino]urea …
Matched Products: … NITROCIN % 2 MERHEM, 56 G …
Synthetic camphor
Approved
Experimental
Matched Synonyms: … 2-bornanone ... 2-camphanone ... 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine ... 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Products: … Fluphenazine 2 Tab 2mg …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Products: … Fluphenazine 2 Tab 2mg …
Trolamine
Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Synonyms: … nitrilo-2,2',2''-triethanol ... tris(2-hydroxyethyl)amine ... 2,2',2''-nitrilotris(ethanol) …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol …
Thymol
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 2-isopropyl-5-methylphenol ... 5-Methyl-2-(1-Methylethyl)Phenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Tinidazole
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Synonyms: … 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Propylthiouracil
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Approved
Investigational
Matched Synonyms: … 4-propyl-2-thiouracil ... 6-propyl-2-thiouracil ... 2-Mercapto-6-propyl-4-pyrimidone …
Matched Iupac: … 6-propyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Iupac: … 6-propyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea ... 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide ... 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Cefotiam
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl ... ]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol ... -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol ... -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ethosuximide
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Approved
Matched Synonyms: … 2-ethyl-2-methylsuccinimide ... (±)-2-ethyl-2-methylsuccinimide ... 2-methyl-2-ethylsuccinimide …
Netupitant
Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai...
Approved
Investigational
Matched Synonyms: … 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Triclosan
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Synonyms: … 2,4,4'-Trichloro-2'-hydroxydiphenyl ether ... 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol …
Matched Iupac: … 5-chloro-2-(2,4-dichlorophenoxy)phenol …
Matched Description: … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy …
Matched Mixtures name: … PREVENT 2 EN 1 …
Matched Products: … DawnMist Deodorant Bar No. 1/2 ... DawnMist Deodorant Bar No. 1 1/2 ... Antibacterial Body Wash Spring Water 2 in 1 …
Matched Iupac: … 5-chloro-2-(2,4-dichlorophenoxy)phenol …
Matched Description: … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy …
Matched Mixtures name: … PREVENT 2 EN 1 …
Matched Products: … DawnMist Deodorant Bar No. 1/2 ... DawnMist Deodorant Bar No. 1 1/2 ... Antibacterial Body Wash Spring Water 2 in 1 …
Nuvaxovid
SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) glycoprotein and angiotensin-converting enzyme 2 (hACE2) expressed on host cells in order to establish a productive infection in humans. Antibodies directed against the S protein are capable of blocking S-hACE2 interactions and neutralizing viral particles...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 rS Nanoparticle Vaccine …
Matched Description: … [L40548,L40553] On July 13, 2022, nuvaxovid was granted an emergency use authorization by the FDA for ... SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) ... glycoprotein and angiotensin-converting enzyme 2 (hACE2) expressed on host cells in order to establish …
Matched Description: … [L40548,L40553] On July 13, 2022, nuvaxovid was granted an emergency use authorization by the FDA for ... SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) ... glycoprotein and angiotensin-converting enzyme 2 (hACE2) expressed on host cells in order to establish …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (b)pyrrole-2-carboxylic acid ... (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Salts cas: … 652969-01-2 …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Salts cas: … 652969-01-2 …
Displaying drugs 76 - 100 of 11695 in total