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Displaying drugs 1 - 25 of 8880 in total

Influenza A virus A/Hawaii/66/2019 (H1N1) live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hawaii/66/2019 (H1N1) live (attenuated) antigen …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …

Omega-3-acid ethyl esters

Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Synonyms: … Omega-3-acid ethyl esters ... Omega-3 fatty acid ethyl esters …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 ... Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand …
Matched Mixtures name: … Omega-3 Well Pack ... Omega-3 Well Pack ... Omega-3 Rx Complete …
Matched Categories: … Fatty Acids, Omega-3 …
Matched Products: … OMEGA 3 DOC ... OMEGA 3 TEVA ... OMEGA 3 MYLAN …

Bordetella pertussis fimbriae 2/3 antigen

Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae (Fim2 and Fim3).
Approved
Investigational
Matched Synonyms: … Bordetella pertussis fimbriae 2/3 vaccine, inactivated …
Matched Name: … Bordetella pertussis fimbriae 2/3 antigen …
Matched Description: … Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella …
Matched Mixtures name: … FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/3 …

1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …

1,2-icosapentoyl-sn-glycero-3-phosphoserine

Approved
Experimental
Matched Name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine …
Matched Iupac: … 2-amino-3-[({2-[(6Z,9Z,12Z,15Z,18Z)-henicosa-6,9,12,15,18-pentaenoyloxy]-3-[(5Z,8Z,11Z,14Z,17Z)-icosa …
Matched Salts name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium …

Phenprocoumon

Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(1-Phenylpropyl)-4-hydroxycoumarin ... 3-(1'-Phenyl-propyl)-4-oxycoumarin ... 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Products: … PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB ... PHENPRO RATIOPHARM 3 MG …

Ciprofloxacin

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Mixtures name: … InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung ... ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET ... ORCIPOL 500 MG/500 MG FILM TABLET, 10 ADET …
Matched Products: … NOVAFLOX EYE DROPS 3 mg/ml ... CILOXAN STERILE OPHTHALMIC OINTMENT 3 mg/g ... ENOXIN 500 TABLET 500 mg …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine …
Matched Products: … XOLYXA 500 MG ... BOSULIF® 500 MG TABLETAS RECUBIERTAS. ... BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET …

Cefaclor

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Synonyms: … 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Mixtures name: … SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADET …
Matched Products: … MEDIKONCEF 500 ... CEC 500 ... CAPABIOTIC 500 …

Gliclazide

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Synonyms: … 1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea ... 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-[(3aR,6aS)-octahydrocyclopenta[c]pyrrol-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Matched Mixtures name: … DUODIA 80/500 MG TABLET, 60 ADET ... DUODİA 80 MG/500 MG TABLET, 30 ADET ... DUODIA 80/500 MG TABLET, 90 ADET …

Tryptophan

An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... L-β-3-indolylalanine ... (S)-α-amino-1H-indole-3-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …

Vadadustat

One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline ... N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …

Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3'-(4''-(β-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine ... 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …

Cycloserine

Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … (+)-4-amino-3-isoxazolidinone ... D-4-amino-3-isoxazolidone ... D-4-amino-3-isoxazolidinone …
Matched Iupac: … (4R)-4-amino-1,2-oxazolidin-3-one …
Matched Products: … SIKLOCAP 250 MG KAPSUL, 500 ADET …

Tagraxofusp

Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Matched Synonyms: … Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …

Mecasermin rinfabate

Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … rhIGF-I/rhIGFBP-3 ... Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … <500 patients worldwide[A176065]. ... (IGFBP-3)[A12605]. ... The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … 3'-Deoxykanamycin B ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 …
Matched Mixtures name: … DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Products: … Braun 3 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET ... TOBEL 80 MG/2 ML AMPUL, 3 ADET …

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … CLOXACAP 500 CAPSULE 500 mg ... คล็อก 500 ... ซาลิน - 500 …

Ethosuximide

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Approved
Matched Synonyms: … 3-ethyl-3-methylsuccinimide ... 3-methyl-3-ethylsuccinimide ... 3-ethyl-3-methyl-2,5-pyrrolidinedione …
Matched Iupac: … 3-ethyl-3-methylpyrrolidine-2,5-dione …

Brompheniramine

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine ... 3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine ... 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …

Dronedarone

Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Synonyms: … N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide ... N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide …
Matched Iupac: … N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide …

Propafenone

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone ... 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …

Ingenol mebutate

Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005 is a selective small molecule activator of protein kinase...
Approved
Matched Synonyms: … 3-Angeloylingenol ... 3-Ingenyl angelate ... Ingenol 3-angelate …

Tegaserod

Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Displaying drugs 1 - 25 of 8880 in total