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Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... 3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA ... DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL …
Matched Description: … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification ... Elapegademase is a PEGylated recombinant adenosine deaminase. …
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is a colorless liquid having disinfectant properties. ... It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … Sooth-a-Sting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … N.A.S.99 Nail Antiseptic Spray ... Coghlans Survival In A Can ... A 50% ISOPROPYL Rubbing Alcohol …
Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Synonyms: … (Alginate)n ... (Alginate)n+1 …
Matched Description: … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated ... It is present in cell walls of brown algae where it forms a viscous gel when binding with water. ... Alginic acid is a linear polymer consisted of L-glucuronic acid and D-mannuronic acid residues connected …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Description: … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least …
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched International brands: … Alferon N
Matched Description: … Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Products: … ANHITEN-A
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched International brands: … Bumaflex N
Matched Description: … for a variety of clinical situations requiring analgesia. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a
Matched Products: … A-NOX FORT 550 MG TABLET, 20 ADET ... NAPROXENO 2.5% POLVO PARA RECONSTITUIR A SUSPENSIÒN ORAL ... NAPROXENO SÓDICO 125MG/5ML POLVO PARA RECONSTITUIR A SUSPENSIÓN. …
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Description: … Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe ... disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase ( ... [A232955] Avalglucosidase alfa is a recombinant form of GAA that restores deficient enzyme levels. …
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … N-methyl-N-guanylglycine ... N-carbamimidoyl-N-methylglycine ... N-(aminoiminomethyl)-N-methylglycine …
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …
Matched Products: … N-EPI ... N-EPI® 1mg/ml Concentrate for Solution for Infusion …
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … Melanowhite-A ... N-acetyltyrosin ... N-acetyl-tyrosine …
Matched Name: … N-acetyltyrosine …
Matched Description: … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor ... [DB00135] is a non-essential amino acid with a polar side group. ... N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced …
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
American hazelnut allergenic extract is used in allergenic testing.
Approved
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia …
Matched Mixtures name: … Extra Once A Day ... Once A Day Tablets ... Maximum Once A Day …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus ... A as it ultimately provides a less burdensome and more convenient dosing regimen for patients that is ... Turoctocog alfa pegol is a pegylated version of [turoctocog alfa]. …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … influenza A virus A/Christchurch/16/2010 (H1N1) antigen …
Matched Name: … Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen …
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (propiolactone inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … N-(5-Nitrofurfurylidene)-1-aminohydantoin …
Matched Description: … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. ... [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole]. …
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Description: … A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Mixtures name: … ZIMODINE N ® ... LAVUZID® N ... CIPLADUOVIR-N TABLETAS …
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-N,N,N-trimethylammonio acetate ... N,N,N-Trimethylglycine ... N,N,N-trimethylammonioacetate …
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. …
Approved
Matched Synonyms: … Haemagglutinin-strain A (H3N2) …
Matched Name: … Haemagglutinin-strain A(H3N2) …
Displaying drugs 1 - 25 of 8730 in total