| DB00182 | Amphetamine | Amphetamine is indicated for the treatment of attention-deficit/hyperactivity disorders (ADHD) as well as for the treatment of central nervous system disorders such as narcolepsy.[A18540]
ADHD is a complex disorder associated with the substantial heterogeneity in etiology, clinical presentation, and treatment outcome. ADHD comes from a complex interplay between interdependent genetic and non-genetic factors which cause complex mental disorders in children and teenagers.[A174271]
On the other hand, narcolepsy is a chronic sleep disorder typically resenting during adolescence and characterized by excessive daytime sleepiness.[A174274]
Amphetamine is also being used nowadays off-label for the treatment of obesity, depression and chronic pain.[A174268, A174283] |
| DB00191 | Phentermine | Phentermine is indicated, alone or in combination with topiramate, as a short-term adjunct, not pass a few weeks, in a regimen of weight reduction based on exercise, behavioral modifications and caloric restriction in the management of exogenous obesity for patients with an initial body mass index (BMI) greater than 30 kg/m2 or greater than 27 kg/m2 in presence of other risk factors such as controller hypertension, diabetes or hyperlipidemia.[FDA label]
Exogenous obesity is considered when the overweight is caused by consuming more food than the person activity level warrants. This condition commonly causes an increase in fat storage. It is an epidemic condition in the United States where over two-thirds of adults are overweight or obese and one in three Americans is obese. In the world, the incidence of obesity has nearly doubled.[A174391] |
| DB00285 | Venlafaxine | For the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain. |
| DB00360 | Sapropterin | For the treatment of tetrahydrobiopterin (BH4) deficiency. |
| DB00574 | Fenfluramine | For the management of exogenous obesity as a short-term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. |
| DB00661 | Verapamil | For the treatment of hypertension, angina, and cluster headache prophylaxis. |
| DB00723 | Methoxamine | Indicated for the treatment and management of hypotension. |
| DB00841 | Dobutamine | For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures |
| DB00852 | Pseudoephedrine | For the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism. |
| DB00865 | Benzphetamine | For the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction |
| DB00867 | Ritodrine | For the treatment and prophylaxis of premature labour |
| DB00938 | Salmeterol | For the treatment of asthma and chronic obstructive pulmonary disease (COPD). |
| DB01001 | Salbutamol | Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known to induce bronchospasm [FDA Label, F3265, F3268]. |
| DB01037 | Selegiline | Monotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression. |
| DB01191 | Dexfenfluramine | For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet |
| DB01255 | Lisdexamfetamine | For the treatment of Attention-deficit/hyperactivity disorder (ADHD) and for moderate to severe binge eating disorder in adults [FDA label], [A40246].
This drug is not indicated for weight loss. Use of other sympathomimetic drugs for weight loss is associated with serious cardiovascular effects. The safety and effectiveness of this drug for the treatment of obesity have not yet been determined [FDA label].
|
| DB01364 | Ephedrine | Ephedrine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia. |
| DB01365 | Mephentermine | Used to maintain blood pressure in hypotensive states. |
| DB01442 | MMDA | MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present. |
| DB01454 | Midomafetamine | Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S. |
| DB01465 | 2,5-Dimethoxyamphetamine | Not Available |
| DB01467 | 2,5-Dimethoxy-4-ethylamphetamine | Not Available |
| DB01472 | 4-Methoxyamphetamine | Not Available |
| DB01482 | Fenethylline | Not Available |
| DB01484 | 4-Bromo-2,5-dimethoxyamphetamine | Not Available |
| DB01509 | 3,4-Methylenedioxyamphetamine | Not Available |
| DB01537 | 4-Bromo-2,5-dimethoxyphenethylamine | Not Available |
| DB01550 | Fenproporex | Fenproporex is used as an appetite suppressant, and anti-obesity agent [2]; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as Brazil, it is still prescribed -- often in the form of diet pills (ie. Brazilian Diet Pills) which combine amphetamines, benzodiazepines, antidepressants, diuretics and laxatives.
In the United States the sale of such diet pills has been banned due to concerns over side effects, and the risk of potentially fatal overdose.
However, internet sales and illicit markets has lead to international availability. It has been found by primary care physicians that Brazilian immigrant women utilized imported diet pills at particularly high rates, and sometimes suffered from side effects requiring hospitalization or experienced a loss of employment. [3] |
| DB01556 | Chlorphentermine | Used as an appetite suppressant. |
| DB01576 | Dextroamphetamine | Used to treat attention deficit hyperactivity disorder (ADHD). |
| DB01577 | Metamfetamine | For the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity. |
| DB04825 | Prenylamine | Not Available |
| DB06152 | Nylidrin | Nylidrin is mainly indicated in conditions like arteriosclerosis, cerebrovascular disease, peripheral vascular disease, Raynaud's disease, thrombo-angitis obliterans, and thrombophlebitis [L2285]. It may sometimes be used in the treatment of peripheral vascular disorders in addition premature labor (however, the drug is not approved for premature labor)[A32531]. |
| DB08941 | Isoxsuprine | Not Available |
| DB08957 | Hexoprenaline | Not Available |
| DB08980 | Fendiline | Not Available |
| DB09022 | Benfluorex | Not Available |
| DB09352 | Hydroxyamphetamine | Mydriatic agent (eye pupil dilatation) for diagnosis of ophthalmic nerve lesions. |
| DB11587 | Etafedrine | Conditions characterized by bronchial congestion and bronchospasm when an expectorant or bronchodilator action is required, such as acute bronchitis, acute episodes of chronic bronchitis and bronchial asthma [L2565], [L2566]. |
| DB11610 | Oxilofrine | Used in combination with [DB11609] as an antitussive [FDA Label]. |
| DB12080 | Ritobegron | Not Available |
| DB12923 | Gallopamil | Not Available |
| DB13108 | Mephedrone | Not Available |
| DB13139 | Levosalbutamol | Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma. |
| DB13561 | Clobenzorex | Not Available |
| DB13624 | Methoxyphenamine | Not Available |
| DB13940 | 2,5-Dimethoxy-4-ethylthioamphetamine | Not Available |
| DB14063 | Dexverapamil | Not Available |
| DB14064 | Emopamil | Not Available |