Phenethylamines
- Name
- Phenethylamines
- Accession Number
- DBCAT000432
- Description
A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)
- Drugs
Drug Drug Description Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Phentermine A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. Sapropterin A cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). Fenfluramine An appetite suppressant used to assist in weight loss for obese patients. Methoxamine An alpha adrenergic agonist used to treat hypotension. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. Ritodrine An adrenergic beta agonist used to treat premature labor. Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Salbutamol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Dexfenfluramine For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet Lisdexamfetamine A central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders. Ephedrine An alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest. Mephentermine A sympathomimetic agent used in the treatment of hypotension. MMDA MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present. Midomafetamine Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used... 2,5-Dimethoxyamphetamine Not Available 2,5-Dimethoxy-4-ethylamphetamine Not Available 4-Methoxyamphetamine Not Available Fenethylline Not Available 4-Bromo-2,5-dimethoxyamphetamine Not Available Tenamfetamine An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons... 4-Bromo-2,5-dimethoxyphenethylamine Not Available Fenproporex Fenproporex is used as an appetite suppressant, and anti-obesity agent [2]; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as... Chlorphentermine Used as an appetite suppressant. Dextroamphetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Isoxsuprine A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease. Hexoprenaline Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Benfluorex Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... Hydroxyamphetamine An indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. Iofetamine I-123 Not Annotated Etafedrine A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa. Oxilofrine An amphetamine used to treat a cough associated with inflamed mucosa. Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Mephedrone Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders. Levosalbutamol A beta-2 adrenergic receptor agonist used to treat COPD and asthma. Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Suloctidil Not Annotated Norfenefrine Not Annotated Oxyfedrine Not Annotated Clobenzorex Not Annotated Methoxyphenamine Not Annotated Gepefrine Not Annotated Mefenorex Not Annotated 2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties. Dexverapamil Not Annotated Emopamil Prevents renal injury after warm & cold ischemia. Methylenedioxyethamphetamine Not Available Hexamethylene diamine Not Available - Drugs & Drug Targets