Bronchodilator Agents

Name
Bronchodilator Agents
Accession Number
DBCAT000555
Description

Agents that cause an increase in the expansion of a bronchus or bronchial tubes.

Drugs
DrugDrug Description
IsoetharineFor the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
HyoscyamineFor treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease...
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
EnprofyllineUsed in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
BitolterolUsed to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive...
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
OxtriphyllineA bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
ColforsinPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;...
UlaritideInvestigated for use/treatment in congestive heart failure.
IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
HexoprenalineHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
FenspirideFenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and...
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
RacepinephrineA bronchodilator used to treat intermittent asthma.
RevefenacinAn anticholinergic agent used to treat COPD.
TulobuterolTulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
NepadutantNepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders.
ReproterolReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
ProxyphyllineNot Annotated
EtamiphyllineNot Annotated
TretoquinolNot Annotated
BufyllineNot Annotated
FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
ZardaverineNot Available
DiphemanilUsed in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration).
PL-3994PL-3994 is under investigation in clinical trial NCT01304628 (Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma).
Drugs & Drug Targets
DrugTargetType
IsoetharineBeta-1 adrenergic receptortarget
IsoetharineBeta-2 adrenergic receptortarget
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
IpratropiumMuscarinic acetylcholine receptor M1target
IpratropiumMuscarinic acetylcholine receptor M2target
IpratropiumMuscarinic acetylcholine receptor M3target
IpratropiumSolute carrier family 22 member 5transporter
IpratropiumSolute carrier family 22 member 4transporter
IpratropiumSerum albumincarrier
Ipratropiumalpha1-acid glycoproteincarrier
HyoscyamineMuscarinic acetylcholine receptor M1target
HyoscyamineMuscarinic acetylcholine receptor M2target
HyoscyamineMuscarinic acetylcholine receptor M3target
HyoscyamineMuscarinic acetylcholine receptor M4target
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
AtropineMuscarinic acetylcholine receptor M2target
AtropineMuscarinic acetylcholine receptor M1target
AtropineMuscarinic acetylcholine receptor M4target
AtropineMuscarinic acetylcholine receptor M5target
AtropineMuscarinic acetylcholine receptor M3target
AtropineGlycine receptor subunit alpha-1target
AtropineNeuronal acetylcholine receptor subunit alpha-4target
AtropineNeuronal acetylcholine receptor subunit beta-2target
AtropineBile salt export pumptransporter
Fluticasone propionateCorticosteroid-binding globulincarrier
Fluticasone propionateCytosolic phospholipase A2target
Fluticasone propionateGlucocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A4enzyme
Fluticasone propionateProgesterone receptortarget
Fluticasone propionateMineralocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A5enzyme
Fluticasone propionateCytochrome P450 3A7enzyme
Fluticasone propionateCytochrome P450 2C8enzyme
Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone propionateP-glycoprotein 1transporter
Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DyphyllineAdenosine receptor A1target
DyphyllineAdenosine receptor A2atarget
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
OrciprenalineBeta-2 adrenergic receptortarget
EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
EnprofyllineAdenosine receptor A2btarget
EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
EnprofyllineAdenosine receptor A1target
EnprofyllineAdenosine receptor A2atarget
EnprofyllineAdenosine receptor A3target
PseudoephedrineAlpha-1A adrenergic receptortarget
PseudoephedrineAlpha-2A adrenergic receptortarget
PseudoephedrineBeta-2 adrenergic receptortarget
PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
PseudoephedrineBeta-1 adrenergic receptortarget
PseudoephedrineSodium-dependent dopamine transportertarget
PseudoephedrineSodium-dependent noradrenaline transportertarget
PseudoephedrineSodium-dependent serotonin transportertarget
PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
PseudoephedrineTumor necrosis factortarget
PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
Pseudoephedrineactivator protein 1target
PseudoephedrineInterleukin-2target
PseudoephedrineSerum albumincarrier
PseudoephedrineSodium-dependent noradrenaline transportertransporter
PseudoephedrineSodium-dependent dopamine transportertransporter
PseudoephedrineSodium-dependent serotonin transportertransporter
TerbutalineBeta-2 adrenergic receptortarget
TerbutalineCholinesteraseenzyme
TerbutalineBeta-3 adrenergic receptortarget
TerbutalineBeta-1 adrenergic receptortarget
BitolterolBeta-2 adrenergic receptortarget
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
SalbutamolBeta-2 adrenergic receptortarget
SalbutamolBeta-1 adrenergic receptortarget
SalbutamolCytochrome P450 3A4enzyme
SalbutamolBeta-3 adrenergic receptortarget
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineMitogen-activated protein kinase 1target
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineCAMP phosphodiesterasetarget
IsoprenalineSuperoxide dismutase [Cu-Zn]target
MequitazineHistamine H1 receptortarget
MequitazineCytochrome P450 2D6enzyme
MequitazineCytochrome P450 3A4enzyme
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
PirbuterolBeta-2 adrenergic receptortarget
PirbuterolBeta-1 adrenergic receptortarget
OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
OxtriphyllineAdenosine receptor A2atarget
OxtriphyllineAdenosine receptor A1target
OxtriphyllineCytochrome P450 1A2enzyme
OxtriphyllineSolute carrier family 22 member 7transporter
OxtriphyllineHistone deacetylase 2target
ProcaterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-nerve growth factortarget
ClenbuterolTumor necrosis factortarget
ClenbuterolBeta-1 adrenergic receptortarget
ClenbuterolBeta-3 adrenergic receptortarget
ClenbuterolCytochrome P450 1A1enzyme
BambuterolBeta-2 adrenergic receptortarget
BambuterolCholinesteraseenzyme
TiotropiumMuscarinic acetylcholine receptor M3target
TiotropiumCytochrome P450 2D6enzyme
TiotropiumCytochrome P450 3A4enzyme
TiotropiumMuscarinic acetylcholine receptor M1target
TiotropiumMuscarinic acetylcholine receptor M2target
TiotropiumSolute carrier family 22 member 5transporter
TiotropiumSolute carrier family 22 member 4transporter
TiotropiumMuscarinic acetylcholine receptor M4target
TiotropiumMuscarinic acetylcholine receptor M5target
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
ColforsinP-glycoprotein 1transporter
ColforsinAdenylate cyclase type 2target
ColforsinGuanine nucleotide-binding protein G(s) subunit alpha isoforms shorttarget
ColforsinAdenylate cyclase type 5target
ColforsinCystic fibrosis transmembrane conductance regulatortarget
UlaritideAtrial natriuretic peptide receptor 1target
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
RevefenacinCytochrome P450 2D6enzyme
RevefenacinMuscarinic acetylcholine receptortarget
RevefenacinSerum albumincarrier
RevefenacinSolute carrier organic anion transporter family member 1B1transporter
RevefenacinSolute carrier organic anion transporter family member 1B3transporter
RevefenacinP-glycoprotein 1transporter
RevefenacinATP-binding cassette sub-family G member 2transporter
TulobuterolBeta-2 adrenergic receptortarget
BamifyllineCytochrome P450 1A2enzyme
ProxyphyllineCytochrome P450 1A2enzyme
EtamiphyllineCytochrome P450 1A2enzyme
BufyllineCytochrome P450 1A2enzyme
FluticasoneCytochrome P450 3A4enzyme
FluticasoneCytochrome P450 2C8enzyme
FluticasoneP-glycoprotein 1carrier
FluticasoneSolute carrier organic anion transporter family member 1B1carrier
FluticasoneP-glycoprotein 1transporter
FluticasoneSolute carrier organic anion transporter family member 1B1transporter
FluticasoneGlucocorticoid receptortarget
FluticasoneCorticosteroid-binding globulincarrier
FluticasoneCytochrome P450 3A5enzyme
FluticasoneCytochrome P450 3A7enzyme
FluticasoneProgesterone receptortarget
FluticasoneCytosolic phospholipase A2target
FluticasoneMineralocorticoid receptortarget
ZardaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DiphemanilMuscarinic acetylcholine receptor M3target