A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.
DrugDrug NameDrug Description
DB00008Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB00022Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
DB00059PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
DB00429Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
DB00446ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
DB00856ChlorphenesinA phenol ether used to treat painful muscular conditions.
DB00949FelbamateAn anticonvulsant used to treat severe epilepsy.
DB01008BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
DB01495DichloralphenazoneDichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension...
DB01563Chloral hydrateA mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia.
DB01839Propylene glycolA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
DB019551,4-ButanediolNot Available
DB022492-EthoxyethanolNot Available
DB028062-MethoxyethanolNot Available
DB03203SphingosineAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
DB03754TromethamineA proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.
DB04978SP1049CIntended for the treatment of carcinoma of the oesophagus.
DB04980LemuteporfinIntended for the treatment of benign prostatic hyperplasia and prostrate disorders.
DB05321PEG-uricaseInvestigated for use/treatment in hyperuricemia.
DB05446LJP 1082Investigated for use/treatment in autoimmune diseases, strokes, and thrombosis.
DB05718Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
DB06154Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
DB06439TyloxapolTyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of...
DB06611PegsunerceptInvestigated for use/treatment in rheumatoid arthritis.
DB06794LodoxamideAn ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
DB06804Nonoxynol-9A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception.
DB06811PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
DB07492BromamphenicolNot Available
DB07565Chloramphenicol succinateA broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains.
DB08621ThiamphenicolNot Available
DB08868FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS).
DB08894PeginesatidePeginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis
DB08904Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
DB09049NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
DB09107Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DB09149Florbetapir (18F)A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment.
DB09208PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
DB09287Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
DB11063Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
DB11077Polyethylene glycol 400An ingredient used in a wide variety of medications, and is not an approved medication.
DB11161Polyethylene glycol 300Indicated as a lubricant in over-the-counter ophthalmic solutions to temporarily relieve redness, burning and irritation of the eyes.
DB11178Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
DB11252Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
DB11304PhenoxyethanolAn antiseptic used as a hand disinfectant or preservative in medications.
DB11333Poloxamer 188A medication used to clean wounds.
DB11413FlorfenicolFlorfenicol is a fluorinated synthetic analog of thiamphenicol.
DB11451PoloxaleneEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen...
DB11567Insulin peglisproNot Annotated
DB11678TreosulfanTreosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
DB11924SafingolSafingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
DB12179SecoisolariciresinolSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
DB12472LevodropropizineLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
DB12842PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
DB13255Propatyl nitrateNot Annotated
DB13526PentaerithritylNot Annotated
DB13583MephenesinA cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis.
DB13650AloglutamolAloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.
DB13785DropropizineNot Annotated
DB13933Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
DB13960BronopolAn antimicrobial compound used as a biocide and preservative.
DB14000TetraglymeNot Annotated
DB14110Butylene glycolNot Annotated
DB14119PhytosphingosineNot Annotated
DB09329Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
DB14656Chlorphenesin carbamateNot Annotated
DB14658Chloramphenicol palmitateNot Annotated
DB02078TriglymeTriethylene glycol dimethyl ether (also called triglyme) is a glycol ether used as a solvent.
DB02327Triethylene glycolNot Available
DB02650TrichloroacetaldehydeNot Available
DB02935DiglymeNot Available
DB14730Calaspargase pegolAn asparagine specific enzyme used to treat acute lymphoblastic leukemia.
DB06592PegargiminaseInvestigated for use/treatment in melanoma and hepatocellular carcinoma.
DB14767Peginterferon lambda-1aPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
DB14951Etirinotecan pegolEtirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
DB14953Firtecan pegolFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
DB15112Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
DB15441Lulizumab pegolLulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome).
DB00019PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
DB09214DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
DB13200LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
DB15140BempegaldesleukinBempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib...
DB15162PegilodecakinPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
DB15365PegbelferminPegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis).
DrugDrug NameTargetType
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2C9enzyme
DB00059PegaspargaseL-asparaginetarget
DB00059PegaspargaseThyroxine-binding globulincarrier
DB00429Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00856ChlorphenesinCytochrome P450 19A1enzyme
DB00856ChlorphenesinCytochrome P450 3A4enzyme
DB00856ChlorphenesinXanthine dehydrogenase/oxidaseenzyme
DB00856ChlorphenesinProstaglandin G/H synthase 2enzyme
DB00856ChlorphenesinCholinesteraseenzyme
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00949FelbamateCytochrome P450 2C9enzyme
DB01008BusulfanDNAtarget
DB01008BusulfanCytochrome P450 3A4enzyme
DB01008BusulfanGlutathione S-transferase A2enzyme
DB01008BusulfanGlutathione S-transferase A1enzyme
DB01008BusulfanGlutathione S-transferase Mu 1enzyme
DB01008BusulfanGlutathione S-transferase Penzyme
DB01008BusulfanMicrosomal glutathione S-transferase 2enzyme
DB01839Propylene glycolCoagulation factor XIII A chaintarget
DB01839Propylene glycolHaloalkane dehalogenasetarget
DB01839Propylene glycolClavaminate synthase 1target
DB01839Propylene glycolLactaldehyde reductasetarget
DB01839Propylene glycolB12-independent glycerol dehydratasetarget
DB019551,4-ButanediolEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB019551,4-ButanediolPhospholipase A2, membrane associatedtarget
DB019551,4-ButanediolGroup IIE secretory phospholipase A2target
DB019551,4-ButanediolRibosomal small subunit pseudouridine synthase Atarget
DB019551,4-ButanediolPenicillin-insensitive murein endopeptidasetarget
DB022492-EthoxyethanolAlcohol dehydrogenase 1Ctarget
DB03203SphingosineGlycolipid transfer proteintarget
DB03203SphingosineP-glycoprotein 1transporter
DB03203SphingosineGenome polyproteintarget
DB03203SphingosineGenome polyproteintarget
DB03203SphingosineGenome polyproteintarget
DB03203SphingosineGenome polyproteintarget
DB03203SphingosinePoliovirus receptortarget
DB03754TromethamineCholera enterotoxin subunit Btarget
DB03754TromethamineS-adenosylmethionine decarboxylase proenzymetarget
DB03754TromethamineBiotin synthasetarget
DB03754TromethamineVascular endothelial growth factor Atarget
DB03754Tromethamine6-phosphogluconolactonasetarget
DB03754TromethamineDecorintarget
DB03754TromethamineAutolysintarget
DB03754TromethamineCytochrome c4target
DB03754TromethamineSoluble calcium-activated nucleotidase 1target
DB03754TromethamineLipoprotein NlpItarget
DB03754TromethamineDNA protection during starvation proteintarget
DB03754TromethaminePutative glucose-6-phosphate 1-epimerasetarget
DB03754TromethamineEndonuclease 8-like 1target
DB04978SP1049CDNA topoisomerase 2-alphatarget
DB05321PEG-uricaseUric acid degradation bifunctional proteintarget
DB05446LJP 1082Beta-2-glycoprotein 1target
DB06154Pentaerythritol tetranitrateHemoglobin subunit alphatarget
DB06154Pentaerythritol tetranitrateHemoglobin subunit betatarget
DB06154Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
DB06154Pentaerythritol tetranitrateFree radicalstarget
DB06154Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
DB06154Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
DB06439TyloxapolLipoprotein lipasetarget
DB06804Nonoxynol-9Prostaglandin G/H synthase 2enzyme
DB07492BromamphenicolDr hemagglutinin structural subunittarget
DB07565Chloramphenicol succinateDr hemagglutinin structural subunittarget
DB08621ThiamphenicolDr hemagglutinin structural subunittarget
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodCytochrome P450 4F12enzyme
DB08868FingolimodHistone deacetylase 1target
DB08894PeginesatideErythropoietin receptortarget
DB08904Certolizumab pegolTumor necrosis factortarget
DB08904Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
DB09049NaloxegolCytochrome P450 3A4enzyme
DB09049NaloxegolCytochrome P450 2D6enzyme
DB09049NaloxegolCytochrome P450 2C19enzyme
DB09049NaloxegolMu-type opioid receptortarget
DB09107Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
DB09122Peginterferon beta-1aCytochrome P450 1A2enzyme
DB09149Florbetapir (18F)Amyloid beta A4 proteintarget
DB09208PegloticaseUric acidtarget
DB11077Polyethylene glycol 400Oxidoreductase HTATIP2target
DB11077Polyethylene glycol 400Cytochrome P450 4A11enzyme
DB11077Polyethylene glycol 400Alcohol dehydrogenase class-3enzyme
DB11077Polyethylene glycol 400Sulfotransferase 1A1enzyme
DB11077Polyethylene glycol 400Ectonucleotide pyrophosphatase/phosphodiesterase family member 1target
DB11567Insulin peglisproCytochrome P450 1A2enzyme
DB13933Nonacog beta pegolCoagulation factor VIItarget
DB13933Nonacog beta pegolCoagulation factor VIIItarget
DB13933Nonacog beta pegolCoagulation factor Xtarget
DB13960BronopolThiol groupstarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
DB02078TriglymeOuter-membrane lipoprotein LolBtarget
DB02078TriglymeProfilin-2target
DB02078TriglymeOuter-membrane lipoprotein LolBtarget
DB02078TriglymeUncharacterized proteintarget
DB02078TriglymeSerine acetyltransferasetarget
DB02078TriglymeTyrosine-protein kinase Fyntarget
DB02078TriglymePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB02078TriglymeTranscriptional regulator, GntR familytarget
DB02078TriglymeABC transporter, periplasmic substrate-binding proteintarget
DB02078TriglymeTransketolasetarget
DB02327Triethylene glycolAcetolactate synthase, catabolictarget
DB02327Triethylene glycolArabinogalactan endo-1,4-beta-galactosidasetarget
DB02327Triethylene glycolPhosphoserine aminotransferasetarget
DB02935DiglymeEndoplasmintarget
DB14730Calaspargase pegolL-asparaginetarget
DB00019PegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB00019PegfilgrastimNeutrophil elastaseenzyme
DB09214DexketoprofenProstaglandin G/H synthase 1target
DB09214DexketoprofenProstaglandin G/H synthase 2target
DB09214DexketoprofenProstaglandin G/H synthase 1enzyme
DB09214DexketoprofenProstaglandin G/H synthase 2enzyme
DB13200LipegfilgrastimGranulocyte colony-stimulating factor receptortarget