Name
Glycols
Accession Number
DBCAT000877
Description

A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.

Drugs
DrugDrug Description
Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
ChlorphenesinA phenol ether used to treat painful muscular conditions.
FelbamateAn anticonvulsant used to treat severe epilepsy.
BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
DichloralphenazoneDichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension...
Chloral hydrateA mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia.
Propylene glycolA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
1,4-ButanediolNot Available
2-EthoxyethanolNot Available
2-MethoxyethanolNot Available
SphingosineAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
TromethamineA proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.
SP1049CIntended for the treatment of carcinoma of the oesophagus.
LemuteporfinIntended for the treatment of benign prostatic hyperplasia and prostrate disorders.
PEG-uricaseInvestigated for use/treatment in hyperuricemia.
LJP 1082Investigated for use/treatment in autoimmune diseases, strokes, and thrombosis.
Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
TyloxapolTyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of...
PegsunerceptInvestigated for use/treatment in rheumatoid arthritis.
LodoxamideAn ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Nonoxynol-9A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception.
PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
BromamphenicolNot Available
Chloramphenicol succinateA broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains.
ThiamphenicolNot Available
FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS).
PeginesatidePeginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis
Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
Florbetapir (18F)A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment.
PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
Polyethylene glycol 400An ingredient used in a wide variety of medications, and is not an approved medication.
Polyethylene glycol 300Indicated as a lubricant in over-the-counter ophthalmic solutions to temporarily relieve redness, burning and irritation of the eyes.
Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
PhenoxyethanolAn antiseptic used as a hand disinfectant or preservative in medications.
Poloxamer 188A medication used to clean wounds.
FlorfenicolFlorfenicol is a fluorinated synthetic analog of thiamphenicol.
PoloxaleneEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen...
Insulin peglisproNot Annotated
TreosulfanTreosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
SafingolSafingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
SecoisolariciresinolSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
LevodropropizineLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
Propatyl nitrateNot Annotated
PentaerithritylNot Annotated
MephenesinA cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis.
AloglutamolAloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.
DropropizineNot Annotated
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
BronopolAn antimicrobial compound used as a biocide and preservative.
TetraglymeNot Annotated
Butylene glycolNot Annotated
PhytosphingosineNot Annotated
Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
Chlorphenesin carbamateNot Annotated
Chloramphenicol palmitateNot Annotated
TriglymeTriethylene glycol dimethyl ether (also called triglyme) is a glycol ether used as a solvent.
Triethylene glycolNot Available
TrichloroacetaldehydeNot Available
DiglymeNot Available
Calaspargase pegolAn asparagine specific enzyme used to treat acute lymphoblastic leukemia.
PegargiminaseInvestigated for use/treatment in melanoma and hepatocellular carcinoma.
Peginterferon lambda-1aPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
Etirinotecan pegolEtirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
Firtecan pegolFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
Lulizumab pegolLulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome).
PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
BempegaldesleukinBempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib...
PegilodecakinPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
PegbelferminPegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis).
AzidamfenicolNot Annotated
DihydroxyphenylglycineNot Available
1,3-PropanediolNot Available
Drugs & Drug Targets
DrugTargetType
Peginterferon alfa-2aInterferon alpha/beta receptor 2target
Peginterferon alfa-2aInterferon alpha/beta receptor 1target
Peginterferon alfa-2aCytochrome P450 1A2enzyme
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme
PegaspargaseL-asparaginetarget
PegaspargaseThyroxine-binding globulincarrier
Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
ChloramphenicolComplement decay-accelerating factortarget
ChloramphenicolDr hemagglutinin structural subunittarget
ChloramphenicolCytochrome P450 2C19enzyme
ChloramphenicolCytochrome P450 3A4enzyme
ChloramphenicolCytochrome P450 3A5enzyme
ChloramphenicolCytochrome P450 3A7enzyme
ChloramphenicolSolute carrier family 22 member 6transporter
Chloramphenicol50S ribosomal protein L16target
ChloramphenicolChloramphenicol acetyltransferase 3enzyme
ChloramphenicolChloramphenicol acetyltransferaseenzyme
ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
ChlorphenesinCytochrome P450 19A1enzyme
ChlorphenesinCytochrome P450 3A4enzyme
ChlorphenesinXanthine dehydrogenase/oxidaseenzyme
ChlorphenesinProstaglandin G/H synthase 2enzyme
ChlorphenesinCholinesteraseenzyme
FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
FelbamateCytochrome P450 2C19enzyme
FelbamateCytochrome P450 3A4enzyme
FelbamateCytochrome P450 2E1enzyme
FelbamateCytochrome P450 2C9enzyme
BusulfanDNAtarget
BusulfanCytochrome P450 3A4enzyme
BusulfanGlutathione S-transferase A2enzyme
BusulfanGlutathione S-transferase A1enzyme
BusulfanGlutathione S-transferase Mu 1enzyme
BusulfanGlutathione S-transferase Penzyme
BusulfanMicrosomal glutathione S-transferase 2enzyme
Propylene glycolCoagulation factor XIII A chaintarget
Propylene glycolHaloalkane dehalogenasetarget
Propylene glycolClavaminate synthase 1target
Propylene glycolLactaldehyde reductasetarget
Propylene glycolB12-independent glycerol dehydratasetarget
1,4-ButanediolEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
1,4-ButanediolPhospholipase A2, membrane associatedtarget
1,4-ButanediolGroup IIE secretory phospholipase A2target
1,4-ButanediolRibosomal small subunit pseudouridine synthase Atarget
1,4-ButanediolPenicillin-insensitive murein endopeptidasetarget
2-EthoxyethanolAlcohol dehydrogenase 1Ctarget
SphingosineGlycolipid transfer proteintarget
SphingosineP-glycoprotein 1transporter
SphingosineGenome polyproteintarget
SphingosineGenome polyproteintarget
SphingosineGenome polyproteintarget
SphingosineGenome polyproteintarget
SphingosinePoliovirus receptortarget
TromethamineCholera enterotoxin subunit Btarget
TromethamineS-adenosylmethionine decarboxylase proenzymetarget
TromethamineBiotin synthasetarget
TromethamineVascular endothelial growth factor Atarget
Tromethamine6-phosphogluconolactonasetarget
TromethamineDecorintarget
TromethamineAutolysintarget
TromethamineCytochrome c4target
TromethamineSoluble calcium-activated nucleotidase 1target
TromethamineLipoprotein NlpItarget
TromethamineDNA protection during starvation proteintarget
TromethaminePutative glucose-6-phosphate 1-epimerasetarget
TromethamineEndonuclease 8-like 1target
SP1049CDNA topoisomerase 2-alphatarget
PEG-uricaseUric acid degradation bifunctional proteintarget
LJP 1082Beta-2-glycoprotein 1target
Pentaerythritol tetranitrateHemoglobin subunit alphatarget
Pentaerythritol tetranitrateHemoglobin subunit betatarget
Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
Pentaerythritol tetranitrateFree radicalstarget
Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
TyloxapolLipoprotein lipasetarget
Nonoxynol-9Prostaglandin G/H synthase 2enzyme
BromamphenicolDr hemagglutinin structural subunittarget
Chloramphenicol succinateDr hemagglutinin structural subunittarget
ThiamphenicolDr hemagglutinin structural subunittarget
FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
FingolimodSphingosine 1-phosphate receptor 5target
FingolimodSphingosine kinase 1enzyme
FingolimodCytochrome P450 2E1enzyme
FingolimodCytochrome P450 4F12enzyme
FingolimodHistone deacetylase 1target
PeginesatideErythropoietin receptortarget
Certolizumab pegolTumor necrosis factortarget
Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
NaloxegolCytochrome P450 3A4enzyme
NaloxegolCytochrome P450 2D6enzyme
NaloxegolCytochrome P450 2C19enzyme
NaloxegolMu-type opioid receptortarget
Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
Peginterferon beta-1aCytochrome P450 1A2enzyme
Florbetapir (18F)Amyloid beta A4 proteintarget
PegloticaseUric acidtarget
Polyethylene glycolP-glycoprotein 1transporter
Polyethylene glycol 400Oxidoreductase HTATIP2target
Polyethylene glycol 400Cytochrome P450 4A11enzyme
Polyethylene glycol 400Alcohol dehydrogenase class-3enzyme
Polyethylene glycol 400Sulfotransferase 1A1enzyme
Polyethylene glycol 400Ectonucleotide pyrophosphatase/phosphodiesterase family member 1target
Polyethylene glycol 400P-glycoprotein 1transporter
Insulin peglisproCytochrome P450 1A2enzyme
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget
BronopolThiol groupstarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
TriglymeOuter-membrane lipoprotein LolBtarget
TriglymeProfilin-2target
TriglymeOuter-membrane lipoprotein LolBtarget
TriglymeUncharacterized proteintarget
TriglymeSerine acetyltransferasetarget
TriglymeTyrosine-protein kinase Fyntarget
TriglymePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
TriglymeTranscriptional regulator, GntR familytarget
TriglymeABC transporter, periplasmic substrate-binding proteintarget
TriglymeTransketolasetarget
Triethylene glycolAcetolactate synthase, catabolictarget
Triethylene glycolArabinogalactan endo-1,4-beta-galactosidasetarget
Triethylene glycolPhosphoserine aminotransferasetarget
DiglymeEndoplasmintarget
Calaspargase pegolL-asparaginetarget
PegfilgrastimGranulocyte colony-stimulating factor receptortarget
PegfilgrastimNeutrophil elastaseenzyme
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
LipegfilgrastimGranulocyte colony-stimulating factor receptortarget
1,3-PropanediolHaloalkane dehalogenasetarget
1,3-PropanediolADP-ribosylation factor 1target