Experimental Unapproved Treatments for COVID-19
- Experimental Unapproved Treatments for COVID-19
- Accession Number
Drugs that are being investigated as potential treatment options for coronavirus disease 2019 (COVID-19). Towards the end of 2019, a large number of patients in Wuhan, China presented with atypical pneumonia. The cause of this disease was identified as 2019 novel coronavirus (2019-nCoV), which was renamed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) on February 11, 2020 by the World Health Organization (WHO).
Drug Drug Description Remdesivir A nucleoside analog used to treat RNA virus infections. Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Chloroquine An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Lopinavir An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. Galidesivir Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various... Favipiravir An antiviral used to manage influenza, and that has the potential to target other viral infections. Umifenovir A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses. Human interferon beta A polypeptide drug used in the treatment of relapsing forms of Multiple Sclerosis (MS). Triazavirin An antiviral used to treat several strains of influenza. TMC-310911 TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections.... mRNA-1273 mRNA-1273 is under investigation in clinical trial NCT04283461 (Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) to Prevent SARS-CoV-2 Infection). Ad5-nCoV Not Annotated ChAdOx1 nCoV-19 Not Annotated Fingolimod A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS). Methylprednisolone A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Bevacizumab A monoclonal anti-vascular endothelial growth factor antibody used in the treatment of many cancer types in combination with other antineoplastics. Leronlimab Investigated for use/treatment in HIV infection. Azithromycin A macrolide antibiotic used to treat a variety of bacterial infections.
- Drugs & Drug Targets