Laboratory Chemicals

Chemicals necessary to perform experimental and/or investigative procedures and for the preparation of drugs and other chemicals.
DrugDrug NameDrug Indication
DB00089Capromab pendetideFor diagnosis of prostate cancer and detection of intra-pelvic metastases.
DB00276AmsacrineFor treatment of acute myeloid leukaemia.
DB00305MitomycinFor treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.
DB00325NitroprussideFor immediate reduction of blood pressure of patients in hypertensive crises, reduce bleeding during surgery, and for the treatment of acute congestive heart failure
DB00345Aminohippuric acidUsed to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
DB00515CisplatinFor the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
DB00522BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
DB00553MethoxsalenFor the treatment of psoriasis and vitiligo
DB00693FluoresceinFor diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.
DB00958CarboplatinFor the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of PARAPLATIN and cyclophosphamide. It is also indicated for the palliative treatment of patients with ovarian carcinoma recurrent after prior chemotherapy, including patients who have been previously treated with cisplatin.
DB01344TolevamerUsed to treat abnormally high potassium levels.
DB01432CholestyramineIndicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction.
DB01638SorbitolUsed as a non-stimulant laxative via an oral suspension or enema.
DB01692DithioerythritolNot Available
DB02041IsoluminolNot Available
DB02166PropidiumNot Available
DB023651,10-PhenanthrolineNot Available
DB026324-nitrophenyl-beta-D-galactosideNot Available
DB02866DansylamideNot Available
DB03166Acetic acidUsed to treat infections in the ear canal.
DB03651Picric acidNot Available
DB03754TromethamineFor the prevention and correction of metabolic acidosis.
DB03825Rhodamine 6GNot Available
DB03902Oxalic AcidNot Available
DB04143Indole-3-Glycerol PhosphateNot Available
DB042144-Nitrophenyl PhosphateNot Available
DB04824PhenolphthaleinUsed for over a century as a laxative.
DB05022AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
DB05528MipomersenUsed in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications.
DB06642BevasiranibInvestigated for use/treatment in macular degeneration and diabetic retinopathy.
DB06704IobenguaneDetection of primary and metastatic pheochromocytoma or neuroblastoma
DB06759FomivirsenIndicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428].
DB06810PlicamycinFor the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
DB07118HymecromoneNot Available
DB07767Ferulic acidNot Available
DB09112Nitrous acidFor sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening [FDA Label].
DB09137Technetium Tc-99m mebrofeninTechnetium Tc 99m Mebrofenin is indicated as a hepatobiliary imaging agent.
DB09138Technetium Tc-99m medronateTechnetium Tc 99m Medronate is indicated for use as a bone imaging agent to delineate areas of altered osteogenesis.
DB09154Sodium citrateUsed as an anticoagulant during plasmophoresis as well as a neutralizing agent in the treatment of upset stomach and acidic urine [FDA Label] [L788] [L789].
DB09161Technetium Tc-99m sestamibiTechnetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects); and 2) evaluating myocardial function and developing information for use in patient management decisions.
DB09163Technetium Tc-99m exametazimeTechnetium Tc99m exametazime scintigraphy (with or without methylene blue stabilization) may be useful as an adjunct in the detection of altered regional cerebral perfusion in stroke. Tc99m exametazime without methylene blue stabilization is indicated for leukocyte labeled scintigraphy as an adjunct in the localization of intra-abdominal infection and inflammatory bowel disease.
DB09164Technetium Tc-99m disofeninTechnetium Tc99m Disofenin is indicated as a hepatobiliary imaging agent. Hepatolite is indicated in the diagnosis of acute cholecystitis as well as to rule out the occurrence of acute cholecystitis in suspected patients with right upper quadrant pain, fever, jaundice, right upper quadrant tenderness and mass or rebound tenderness, but not limited to these signs and symptoms.
DB09165Technetium Tc-99m pyrophosphateFor use as a skeletal imaging agent used to demonstrate areas of altered osteogenesis, and a cardiac imaging agent used as an adjunct in the diagnosis of acute myocardial infarction [FDA Label]. May also be used to image gated blood pools and detect gastrointetinal bleeding.
DB09314Technetium Tc-99m pertechnetateSodium Pertechnetate Tc99m Injection is indicated for use in adults for imaging in the following tissues: thyroid, salivary gland, urinary bladder (for detection of vesico-ureteral reflux), and nasolacrimal drainage system (dacryoscintigraphy). It is indicated for use in children for imaging the following tissues: thyroid and urinary bladder.
DB09397Technetium Tc-99m sulfur colloidTechnetium 99m sulfur colloid is indicated as a diagnostic agent in adults for the following tests: localization of lymph nodes draining a primary tumor in patients with breast cancer or malignant melanoma; and evaluation of peritoneo-venous (LeVeen) shunt patency. It is indicated in both adult and pediatric patients for: imaging areas of functioning reticuloendothelial cells in the liver, spleen and bone marrow; and studies of esophageal transit and gastroesophageal reflux, and detection of pulmonary aspiration of gastric contents.
DB09413Monopotassium phosphateUsed in buffers (determination of pH, pharmaceutical production, urinary acidifier, paper processing, baking powder, and food), nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications; Used as a nutritional supplement in foods, a nonlinear optical material for laser use, and in wastewater treatment;
DB09414Dipotassium phosphateDipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures as an additive. It is used in non-dairy creamers to prevent coagulation. Dipotassium phosphate is also used to make buffer solutions and it is used in the production of trypticase soy agar which is used to make agar plates for culturing bacteria.
DB09480Iofetamine I-123Not Available
DB09502Fludeoxyglucose (18F)The uptake of 18F-FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types of tissue metabolism. Fludeoxyglucose F 18 Injection is indicated in positron emission tomography (PET) imaging for assessment of abnormal glucose metabolism to assist in the evaluation of malignancy in patients with known or suspected abnormalities found by other testing modalities, or in patients with an existing diagnoses of cancer.
DB11153Potassium hydroxide Medically, the microscopic examination of potassium hydroxide (KOH) preparations is utilized in the diagnosis of fungal hyphae or trichomonads [L1950]. Samples from hair, skin, or nail tissue are obtained by scraping with a scalpel, cotton-tipped applicator and are inoculated directly onto the KOH solution [L1950]. In addition to the above, potassium hydroxide is used as a softener for nail grooves [L1949].
DB11283DL-dimyristoylphosphatidylcholineDL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication.
DB11561AminacrineNot Available
DB11592NitrocefinNot Available
DB11601Tuberculin Purified Protein DerivativeIndicated as a diagnostic agent in Mantoux Test used to detect infection with *Mycobacterium tuberculosis*.
DB11831DinitrochlorobenzeneNot Available
DB12352BizelesinNot Available
DB12549PyrazoloacridineNot Available
DB12602PentetreotideNot Available
DB12944PhloroglucinolNot Available
DB13212PhenolsulfonphthaleinNot Available
DB13215SulfobromophthaleinNot Available
DB13706EosinNot Available
DB13831Potassium permanganateNot Available
DB13911Phloxine BFor use in dental disclosing products, allowing for highlighting of bacterial placques.
DB13960BronopolBronopol as an active ingredient is registered as a commercial biocide and preservative in many industrial processes. Registered biocidal uses include pulp and paper mills, water cooling towers, waste water treatment, evaporative condensers, heat exchangers, food pasteurizing plants, metalworking fluids, and oilfield applications [F2317]. In addition, preservative uses include household products (e.g., dishwashing liquids, laundry products), latex emulsions, polymer lattices, pigments, leather and milk samples for analysis [F2317]. Bronopol is also formulated into granular domestic end-use products in the form of cat litter [F2317].
DB14141p-PhenylenediamineNot Available
DB14582PatisiranPatisirant is indicated for the treatment of hereditary transthyretin-mediated amyloidosis in adults [FDA Label]. It is administered with pre-medication to reduce complications [FDA Label]. These include an intravenous corticosteroid equivalent to 10 mg of dexamethasone, 500 mg of oral acetaminophen, an intravenous histamine H1 blocker equivalent to 50 mg of diphenhydramine, and an intravenous histamine H2 blocker equivalent to 50 mg of ranitidine
DB14708TosylchloramideNot Available
DB12257PlatinumNot Available
DB02240Quinacrine mustardNot Available
DB02751GlycocyamineNot Available
DB02930Adenosine 5'-[γ-thio]triphosphateNot Available
DB03266GlutaralNot Available
DB09151Flutemetamol (18F)Flutemetamol F18 is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
DB09160Technetium Tc-99m tetrofosminTechnetium-99m tetrofosmin is indicated for the diagnosis of heart abnormalities by exercise myocardial scintigraphy. The exercise myocardial scintigraphy is an established method for the diagnosis of the severity of coronary artery disease.[A31592] This method allows distinguishing regions of reversible myocardial ischemia in the presence or absence of infarcted myocardium following rest and stress conditions.[L1147] The use of technetium-99m tetrofosmin is mainly used to assess myocardial perfusion in ischemia and infarction.[L1146]
DB13811OblimersenNot Available
DB14713InotersenInotersen is a transthyretin-directed antisense oligonucleotide indicated for treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults [FDA label], [F1938].
DB14901InclisiranNot Available
DB14907Bevacizumab zirconium Zr-89Not Available
DB15058FlutemetamolNot Available
DB15134Fluoroazomycin arabinoside F-18Not Available
DrugDrug NameTargetType
DB00089Capromab pendetideGlutamate carboxypeptidase 2target
DB00276AmsacrineDNA topoisomerase 2-alphatarget
DB00276AmsacrinePotassium voltage-gated channel subfamily H member 2target
DB00276AmsacrineP-glycoprotein 1transporter
DB00276AmsacrineAlpha-1-acid glycoprotein 1target
DB00276AmsacrineSerum albumintarget
DB00305MitomycinNADPH--cytochrome P450 reductaseenzyme
DB00325NitroprussideAtrial natriuretic peptide receptor 1target
DB00325NitroprussideCytochrome P450 1A1enzyme
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00515CisplatinCanalicular multispecific organic anion transporter 2transporter
DB00515CisplatinMultidrug resistance-associated protein 5transporter
DB00515CisplatinCanalicular multispecific organic anion transporter 1transporter
DB00515CisplatinSolute carrier family 22 member 2transporter
DB00515CisplatinHigh affinity copper uptake protein 1transporter
DB00515CisplatinProbable low affinity copper uptake protein 2transporter
DB00515CisplatinMultidrug resistance-associated protein 6transporter
DB00515CisplatinP-glycoprotein 1transporter
DB00515CisplatinCopper-transporting ATPase 2transporter
DB00515CisplatinCopper-transporting ATPase 1transporter
DB00515CisplatinProstaglandin G/H synthase 2enzyme
DB00515CisplatinXanthine dehydrogenase/oxidaseenzyme
DB00515CisplatinArylamine N-acetyltransferaseenzyme
DB00515CisplatinCytochrome P450 2C9enzyme
DB00515CisplatinCytochrome P450 2B6enzyme
DB00515CisplatinCytochrome P450 4A11enzyme
DB00515CisplatinATP-binding cassette sub-family G member 2transporter
DB00515CisplatinGlutathione S-transferase theta-1enzyme
DB00515CisplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00515CisplatinGlutathione S-transferase Penzyme
DB00515CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00515CisplatinGlutathione S-transferase Mu 1enzyme
DB00515CisplatinDNA-3-methyladenine glycosylasetarget
DB00515CisplatinSerum albumincarrier
DB00515CisplatinCopper transport protein ATOX1target
DB00522BentiromideSerine protease hepsintarget
DB00553MethoxsalenCytochrome P450 2A6enzyme
DB00553MethoxsalenCytochrome P450 1A2enzyme
DB00553MethoxsalenCytochrome P450 1A1enzyme
DB00553MethoxsalenCytochrome P450 2A13enzyme
DB00693FluoresceinIg kappa chain V-II region RPMI 6410target
DB00693FluoresceinSolute carrier family 22 member 6transporter
DB00693FluoresceinBile salt export pumptransporter
DB00693FluoresceinMultidrug resistance-associated protein 1transporter
DB00958CarboplatinHigh affinity copper uptake protein 1transporter
DB00958CarboplatinProbable low affinity copper uptake protein 2transporter
DB00958CarboplatinXanthine dehydrogenase/oxidaseenzyme
DB00958CarboplatinGlutathione S-transferase theta-1enzyme
DB00958CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00958CarboplatinGlutathione S-transferase Penzyme
DB00958CarboplatinGlutathione S-transferase Mu 1enzyme
DB00958CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00958CarboplatinCopper-transporting ATPase 1transporter
DB00958CarboplatinCopper-transporting ATPase 2transporter
DB00958CarboplatinATP-binding cassette sub-family G member 2transporter
DB00958CarboplatinCanalicular multispecific organic anion transporter 1transporter
DB01432CholestyramineBile acidstarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB01692DithioerythritolListeriolysin regulatory proteintarget
DB01692Dithioerythritol6,7-dimethyl-8-ribityllumazine synthasetarget
DB01692DithioerythritolThymidine kinase, cytosolictarget
DB02041IsoluminolQueuine tRNA-ribosyltransferasetarget
DB023651,10-PhenanthrolineMethyl-accepting chemotaxis protein IItarget
DB023651,10-PhenanthrolineMetallo-beta-lactamase L1target
DB026324-nitrophenyl-beta-D-galactosideGalactoside O-acetyltransferasetarget
DB02866DansylamideCarbonic anhydrase 2target
DB03166Acetic acidSolute carrier organic anion transporter family member 2B1transporter
DB03166Acetic acidMonocarboxylate transporter 1transporter
DB03651Picric acidPentaerythritol tetranitrate reductasetarget
DB03754TromethamineCholera enterotoxin subunit Btarget
DB03754TromethamineS-adenosylmethionine decarboxylase proenzymetarget
DB03754TromethamineBiotin synthasetarget
DB03754TromethamineVascular endothelial growth factor Atarget
DB03754TromethamineCytochrome c4target
DB03754TromethamineSoluble calcium-activated nucleotidase 1target
DB03754TromethamineLipoprotein NlpItarget
DB03754TromethamineDNA protection during starvation proteintarget
DB03754TromethaminePutative glucose-6-phosphate 1-epimerasetarget
DB03754TromethamineEndonuclease 8-like 1target
DB03825Rhodamine 6GHTH-type transcriptional regulator QacRtarget
DB03825Rhodamine 6GAcriflavine resistance protein Btarget
DB03825Rhodamine 6GMultidrug resistance-associated protein 1transporter
DB03902Oxalic AcidProto-oncogene tyrosine-protein kinase Srctarget
DB03902Oxalic AcidSolute carrier organic anion transporter family member 2B1transporter
DB03902Oxalic AcidSolute carrier family 22 member 8transporter
DB04143Indole-3-Glycerol PhosphateTryptophan synthase alpha chaintarget
DB04143Indole-3-Glycerol PhosphateTryptophan synthase beta chaintarget
DB042144-Nitrophenyl PhosphateLow molecular weight phosphotyrosine protein phosphatasetarget
DB042144-Nitrophenyl PhosphateDual specificity protein phosphatase 23target
DB04824PhenolphthaleinUDP-glucuronosyltransferase 1-9target
DB04824PhenolphthaleinNuclear receptor subfamily 1 group I member 2target
DB04824PhenolphthaleinNuclear receptor subfamily 1 group I member 3target
DB04824PhenolphthaleinEstrogen receptor alphatarget
DB04824PhenolphthaleinSex hormone-binding globulintarget
DB05022AmonafideDNA topoisomerase 2-alphatarget
DB05022AmonafideDNA topoisomerase 2-betatarget
DB05528MipomersenmRNA of ApoB-100target
DB06642BevasiranibVascular endothelial growth factor Atarget
DB06704IobenguaneSodium-dependent noradrenaline transportertransporter
DB06759Fomivirsen30 kDa immediate-early protein 2target
DB06759Fomivirsen45 kDa immediate-early protein 2target
DB07118HymecromoneArylsulfate sulfotransferasetarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ytarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ztarget
DB07767Ferulic acidEst1etarget
DB07767Ferulic acidO-methyltransferasetarget
DB09112Nitrous acidHemoglobin subunit alphatarget
DB09112Nitrous acidHemoglobin subunit betatarget
DB09112Nitrous acidMyoglobintarget
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B1transporter
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B3transporter
DB09154Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
DB09154Sodium citrateSolute carrier family 13 member 2transporter
DB09154Sodium citrateSolute carrier family 13 member 5transporter
DB09154Sodium citrateTricarboxylate transport protein, mitochondrialtransporter
DB09161Technetium Tc-99m sestamibiP-glycoprotein 1transporter
DB09161Technetium Tc-99m sestamibiMultidrug resistance-associated protein 1transporter
DB09165Technetium Tc-99m pyrophosphateHydroxyapatitetarget
DB09165Technetium Tc-99m pyrophosphateAmorphous calcium phosphatetarget
DB09413Monopotassium phosphateIntestinal-type alkaline phosphataseenzyme
DB09502Fludeoxyglucose (18F)Hexokinase-1enzyme
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 4transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 2transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 1transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 3transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 9transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 5transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 6transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 7transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 8transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 10transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 11transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 12transporter
DB11601Tuberculin Purified Protein DerivativeToll-like receptor 2target
DB11831DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DB11831DinitrochlorobenzeneGlutathione S-transferase Ptarget
DB13960BronopolThiol groupstarget
DB14582PatisiranTransthyretin mRNAtarget
DB14582PatisiranSerum albumincarrier
DB14582Patisiranalpha1-acid glycoproteincarrier
DB02240Quinacrine mustardTrypanothione reductasetarget
DB02751GlycocyamineGuanidinoacetate N-methyltransferasetarget
DB02930Adenosine 5'-[γ-thio]triphosphateProtein RecAtarget
DB02930Adenosine 5'-[γ-thio]triphosphateADP-ribosyl cyclase 2target
DB02930Adenosine 5'-[γ-thio]triphosphateProtein RecAtarget
DB02930Adenosine 5'-[γ-thio]triphosphateProtein RecAtarget
DB02930Adenosine 5'-[γ-thio]triphosphateSynapsin-1target
DB02930Adenosine 5'-[γ-thio]triphosphate[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrialtarget
DB02930Adenosine 5'-[γ-thio]triphosphateChloramphenicol 3-O phosphotransferasetarget
DB02930Adenosine 5'-[γ-thio]triphosphatePhosphoribosylglycinamide formyltransferase 2target
DB02930Adenosine 5'-[γ-thio]triphosphate6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1target
DB02930Adenosine 5'-[γ-thio]triphosphateSerine/threonine-protein kinase PknBtarget
DB02930Adenosine 5'-[γ-thio]triphosphateATP-dependent DNA helicase RecQtarget
DB02930Adenosine 5'-[γ-thio]triphosphateCag alphatarget
DB02930Adenosine 5'-[γ-thio]triphosphateMismatch repair endonuclease PMS2target
DB02930Adenosine 5'-[γ-thio]triphosphateDNA polymerase III subunit tautarget
DB09151Flutemetamol (18F)Amyloid beta A4 proteintarget
DB09160Technetium Tc-99m tetrofosminP-glycoprotein 1carrier
DB14713InotersenTransthyretin mRNAtarget