Immunosuppressive Agents

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
DrugDrug NameDrug Description
DB00005EtanerceptA protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis.
DB00074BasiliximabA monoclonal anti-C25 antibody (interleukin-2 receptor alpha subunit) used as immunosuppressive therapy in kidney transplant patients.
DB00075MuromonabA monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB00111DaclizumabA monoclonal anti-CD25 antibody that blocks the interleukin-2 receptor which is used to treat relapsing forms of multiple sclerosis.
DB00242CladribineA purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.
DB00688Mycophenolate mofetilAn inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.
DB00864TacrolimusA calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
DB00877SirolimusAn immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis.
DB00993AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
DB01024Mycophenolic acidAn immunosuppressant used to prevent organ transplant rejections.
DB01041ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
DB01097LeflunomideA pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
DB01281AbataceptA disease-modifying antirheumatic drug (DMARD) used for the management of moderate-to-severe active rheumatoid arthritis and active polyarticular juvenile idiopathic arthritis as monotherapy or in combination with other DMARDs.
DB01590EverolimusA mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
DB06681BelataceptA selective T-cell costimulation blocker used in the prophylaxis of organ rejection in adult patients receiving a kidney transplant.
DB08868FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS).
DB08879BelimumabA B-lymphocyte stimulator (BLyS)-specific inhibitor that indirectly inhibits B cell survival, and is used to treat patients with autoantibody positive, active systemic lupus erythematosus.
DB08880TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
DB08904Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
DB06168CanakinumabAn interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA).
DB09033VedolizumabAn integrin blocker and anti-inflammatory agent used to manage ulcerative colitis and Crohn's disease in adults with inadequate clinical response to immunomodulators.
DB09036SiltuximabAn interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative.
DB12692GusperimusGusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.
DB11693VoclosporinVoclosporin is a novel cyclosporine analog and immunosuppressive compound currently being investigated for the treatment of psoriasis and for the prevention of organ rejection in kidney transplant patients. All studies...
DB09312Antilymphocyte immunoglobulin (horse)A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients.
DB06612MepolizumabAn IL-5 antagonist used as an add-on maintenance treatment of patients with severe eosinophilic asthma in adults.
DB00441GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
DB00531CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DB00544FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
DB00563MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB00987CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
DB01008BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
DB01033MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
DB01042MelphalanAn alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma.
DB01073FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
DB04572ThiotepaAn alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
DB05259GlatiramerAn immunomodulator used to reduce the frequency of relapses in Multiple Sclerosis (MS).
DB00026AnakinraA recombinant form of human interleukin-1 receptor antagonist used in the treatment of rheumatoid arthritis and neonatal-onset multisystem inflammatory disease.
DB00051AdalimumabA monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
DB00065InfliximabA monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
DB00087AlemtuzumabA monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis.
DB00098Antithymocyte immunoglobulin (rabbit)A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants.
DB00108NatalizumabA monoclonal anti-integrin antibody which binds to the alpha 4 subunit of integrins to prevent migration of immune cells, and is used to treat Crohn's disease or multiple sclerosis.
DB00480LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DB01257EculizumabA recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
DB05679UstekinumabA targeted antibody therapy used to manage inflammatory conditions such as plaque psoriasis, psoriatic arthritis, Crohn's Disease, and ulcerative colitis.
DB06273TocilizumabAn interleukin-6 (IL-6) receptor antagonist used to treat Cytokine Release Syndrome (CRS), Systemic Juvenile Idiopathic Arthritis (sJIA), Giant Cell Arteritis (GCA), and Rheumatoid Arthritis (RA).
DB06372RilonaceptAn IL-1 inhibitor used to treat cryopyrin-associated periodic syndrome, a rare hereditary inflammatory disorder.
DB06674GolimumabA TNFα inhibitor used in the symptomatic treatment of various active inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis.
DB08895TofacitinibA Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine.
DB08910PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
DB09029SecukinumabAn immunomodulating agent and interleukin antagonist used to manage moderate to severe plaque psoriasis and active psoriatic arthritis or ankylosing spondylitis.
DB00056Gemtuzumab ozogamicinA monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia.
DB00059PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
DB00073RituximabA monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
DB00078Ibritumomab tiuxetanA monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope.
DB00081TositumomabA monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope.
DB00120L-PhenylalanineAn amino acid commonly found as a component of total parenteral nutrition.
DB00262CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
DB00276AmsacrineA cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents.
DB00290BleomycinA chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others.
DB00291ChlorambucilA chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas.
DB00305MitomycinAn antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
DB00309VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
DB00322FloxuridineAn antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
DB00352TioguanineA purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
DB00361VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
DB00398SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
DB00428StreptozocinA nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma.
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB00444TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
DB00445EpirubicinAn anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
DB00488AltretamineAn antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
DB00515CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
DB00526OxaliplatinA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DB00552PentostatinAn adenosine deaminase inhibitor used to treat hairy cell leukemia.
DB00570VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
DB00619ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
DB00631ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB00642PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
DB00687FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
DB00694DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
DB00724ImiquimodA toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB00755TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
DB00762IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
DB00773EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
DB00851DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
DB00853TemozolomideAn alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00888MechlorethamineAn antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
DB00928AzacitidineA pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
DB00958CarboplatinA alkylating agent used to treat advanced ovarian cancer.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00970DactinomycinAn actinomycin used to treat a wide variety of cancers.
DB00997DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
DB01005HydroxyureaAn antimetabolite used to treat sickle cell anemia crisis.
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
DB01101CapecitabineA nucleoside metabolic inhibitor indicated to treat colon, colorectal and breast cancer.
DB01168ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
DB01177IdarubicinAn anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
DB01181IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
DB01196EstramustineAn antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
DB01204MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
DB01206LomustineAn alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
DB01222BudesonideA corticosteroid used in the management of asthma, nasal polyposis, and rhinitis via inhalation, as well as mild to moderate active Crohn's disease and ulcerative colitis via ingestion.
DB01229PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB01248DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
DB01254DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
DB01268SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
DB01280NelarabineA purine nucleoside analog and antineoplastic agent used for the treatment of with acute T-cell lymphoblastic leukemia and T-cell lymphoblastic lymphoma with inadequate clinical response to prior chemotherapeutic treatments.
DB01285CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB04868NilotinibA kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
DB05109TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
DB05773Trastuzumab emtansineAn antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
DB06287TemsirolimusA antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
DB06589PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
DB06603PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
DB06772CabazitaxelAn antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
DB06813PralatrexateAn antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma.
DB08870Brentuximab vedotinA CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
DB08877RuxolitinibA kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
DB08935ObinutuzumabAn antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil.
DB09052BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
DB09053IbrutinibAn antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
DB09054IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
DB09073PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
DB09077DinutuximabAn immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
DB09082VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DB00222GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
DB00337PimecrolimusA topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
DB01423SteproninStrepronin is a mucolytic (expectorant) drug.
DB01816CastanospermineNot Available
DB028062-MethoxyethanolNot Available
DB04258SeocalcitolNot Available
DB05260Gallium nitrateA medication indicated for cancer-related hypercalcemia.
DB08908Dimethyl fumarateA medication used to treat patients with the relapsing-remitting form of multiple sclerosis.
DB11616PirarubicinNot Annotated
DB11921DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
DB12025TriptolideTriptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.
DB12617MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
DB12902TrofosfamideTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
DB12947DoxifluridineDoxifluridine has been investigated for the treatment of Stomach Cancer.
DB12991DeoxyspergualinDeoxyspergualin has been used in trials studying the treatment of Lupus Nephritis, Chronic Rejection, and Diabetes Mellitus, Type 1.
DB12996ActeosideActeoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
DB13014HypericinHypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
DB00092AlefaceptA recombinant fusion protein that binds CD2 and is used treat moderate to severe plaque psoriasis.
DB00095EfalizumabA monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis.
DB04951PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
DB04956AfelimomabInvestigated for use/treatment in sepsis and septicemia.
DB05676ApremilastA non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis.
DB06662AbetimusInvestigated for use/treatment in kidney disease and systemic lupus erythematosus.
DB11776BrodalumabA monoclonal antibody used to treat moderate to severe plaque psoriasis.
DB13241BegelomabNot Annotated
DB08059WortmanninWortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
DB130689-(N-methyl-L-isoleucine)-cyclosporin A9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.
DB00008Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB00018Interferon alfa-n3A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
DB00022Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
DB00041AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
DB00069Interferon alfacon-1A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections.
DB00112BevacizumabA monoclonal anti-vascular endothelial growth factor antibody used in the treatment of many cancer types in combination with other antineoplastics.
DB00188BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
DB00293RaltitrexedA folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
DB00307BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
DB00380DexrazoxaneA cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
DB00446ChloramphenicolA broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
DB00495ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
DB00550PropylthiouracilA thiourea antithyroid agent used to treat hyperthyroidism.
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB00601LinezolidAn oxazolidinone antibiotic used to treat susceptible strains of multidrug resistant bacterial infections.
DB00763MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
DB01099FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
DB01169Arsenic trioxideA chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.
DB01262DecitabineA chemotherapeutic agent used for the treatment of myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, and conditions related to refractory anemia.
DB02546VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
DB04845IxabepiloneA microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.
DB05015BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
DB06616BosutinibAn antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
DB06769BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
DB08871EribulinA microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.
DB08889CarfilzomibA proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.
DB08901PonatinibA kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
DB09042Tedizolid phosphateAn antibiotic agent used to treat acute bacterial skin and skin structure infections caused by susceptible isolates of Gram-positive bacteria.
DB09074OlaparibA chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.
DB11767SarilumabA monoclonal antibody used to treat moderate to severe rheumatoid arthritis who have responded poorly or are intolerant of other DMARDs.
DB05459BriakinumabInvestigated for use/treatment in autoimmune diseases, crohn's disease, multiple sclerosis, psoriasis and psoriatic disorders, and rheumatoid arthritis.
DB11466TepoxalinTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...
DB14066TetrandrineNot Annotated
DB00795SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
DB01611HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
DB00432TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
DB04630AldosteroneA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
DB01108TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
DB13208PrednylidenePrednylidene is an experimental systemic glucocorticoid.
DB01384ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
DB09383MeprednisoneNot Annotated
DB11529MelengestrolMelengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
DB09378FluprednisoloneA synthetic glucocorticoid with anti-inflammatory properties.
DB00180FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
DB13003CortivazolCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
DB13843CloprednolCloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
DB00240AlclometasoneA topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
DB00288AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
DB01410CiclesonideA glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
DB11750ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
DB01013Clobetasol propionateA corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
DB13158ClobetasoneA corticosteroid used to treat dry eyes, eczema, and dermatitis.
DB00838ClocortoloneA corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
DB01260DesonideA topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
DB00547DesoximetasoneA glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB11487Dexamethasone isonicotinateDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
DB00223DiflorasoneA topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
DB09095DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DB06781DifluprednateA topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
DB13856FlucloroloneNot Annotated
DB00663FlumethasoneA corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
DB00591Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
DB01047FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
DB13223FluocortinFluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain .
DB08971FluocortoloneFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
DB00324FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
DB13491FluperoloneNot Annotated
DB08970FluprednideneFluprednidene is a corticosteroid.
DB00846FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
DB13867FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
DB08906Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB13664FormocortalNot Annotated
DB06786HalcinonideA corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
DB13728HalometasoneNot Annotated
DB14538Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB14543Hydrocortisone probutateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB14540Hydrocortisone butyrateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB14545Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB14544Hydrocortisone valerateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB14596Loteprednol etabonateA corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery.
DB00253MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
DB00764MometasoneA corticosteroid used to treat asthma and allergic rhinitis.
DB14512Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
DB01130PrednicarbateA medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
DB00896RimexoloneA glucocorticoid used to treat inflammation of the eye.
DB09091TixocortolA corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis.
DB00596UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB11988OcrelizumabA CD20 specific monoclonal antibody used to treat relapsing remitting multiple sclerosis.
DB00072TrastuzumabA monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers.
DB06643DenosumabA RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
DB14219Monomethyl fumarateNot Annotated
DB00859PenicillamineA chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis.
DB00328IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
DB03523BrequinarNot Available
DB00033Interferon gamma-1bA form of recombinant human interferon used to treat infections associated with chronic granulomatous disease and to slow the progression of severe malignant osteopetrosis.
DB05472omega interferonInvestigated for use/treatment in hepatitis (viral, C).
DB00011Interferon alfa-n1A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DB12814Cepeginterferon alfa-2BCepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
DB00068Interferon beta-1bA form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms.
DB00034Interferon alfa-2a, RecombinantA form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB05258Interferon alfaInvestigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
DB00105Interferon alfa-2bA form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
DB11569IxekizumabA monoclonal antibody used to treat moderate to severe plaque psoriasis.
DB11803SirukumabSirukumab has been used in trials studying the treatment and basic science of Giant Cell Arteritis and Arthritis, Rheumatoid.
DB11817BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
DB11834GuselkumabA monoclonal antibody used to treat moderate to severe plaque psoriasis.
DB12612OzanimodOzanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclerosis.
DB14724EmapalumabAn interferon gamma blocking antibody used to treat primary hemophagocytic lymphohistiocytosis.
DB12371SiponimodA medication used to treat relapsing multiple sclerosis.
DB14762RisankizumabAn interleukin-23 antagonist used to treat moderate to severe plaque psoriasis.
DB15253BleselumabBleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant...
DB00394Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
DB11580RavulizumabA monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria.
DB11708PeficitinibPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
DB14919RozanolixizumabRozanolixizumab is under investigation in clinical trial NCT03861481 (A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy).
DB01394ColchicineAn alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
DB15527UmirolimusNot Annotated
DrugDrug NameTargetType
DB00005EtanerceptTumor necrosis factortarget
DB00005EtanerceptLymphotoxin-alphatarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00005EtanerceptComplement C1r subcomponenttarget
DB00005EtanerceptComplement C1q subcomponent subunit Atarget
DB00005EtanerceptComplement C1q subcomponent subunit Btarget
DB00005EtanerceptComplement C1q subcomponent subunit Ctarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00005EtanerceptComplement C1s subcomponenttarget
DB00005EtanerceptHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00005EtanerceptTumor necrosis factor receptor superfamily member 1Btarget
DB00074BasiliximabInterleukin-2 receptor subunit alphatarget
DB00074BasiliximabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00074BasiliximabComplement C1r subcomponenttarget
DB00074BasiliximabComplement C1q subcomponent subunit Atarget
DB00074BasiliximabComplement C1q subcomponent subunit Btarget
DB00074BasiliximabComplement C1q subcomponent subunit Ctarget
DB00074BasiliximabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00074BasiliximabComplement C1s subcomponenttarget
DB00074BasiliximabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00074BasiliximabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00074BasiliximabInterleukin-2 receptor subunit betatarget
DB00074BasiliximabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00074BasiliximabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00075MuromonabT-cell surface glycoprotein CD3 epsilon chaintarget
DB00075MuromonabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00075MuromonabComplement C1r subcomponenttarget
DB00075MuromonabComplement C1q subcomponent subunit Atarget
DB00075MuromonabComplement C1q subcomponent subunit Btarget
DB00075MuromonabComplement C1q subcomponent subunit Ctarget
DB00075MuromonabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00075MuromonabComplement C1s subcomponenttarget
DB00075MuromonabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00075MuromonabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00075MuromonabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00075MuromonabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00075MuromonabT-cell surface glycoprotein CD3 delta chaintarget
DB00075MuromonabT-cell surface glycoprotein CD3 gamma chaintarget
DB00075MuromonabT-cell surface glycoprotein CD3 zeta chaintarget
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB00111DaclizumabInterleukin-2 receptor subunit alphatarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00111DaclizumabComplement C1r subcomponenttarget
DB00111DaclizumabComplement C1q subcomponent subunit Atarget
DB00111DaclizumabComplement C1q subcomponent subunit Btarget
DB00111DaclizumabComplement C1q subcomponent subunit Ctarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00111DaclizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00111DaclizumabInterleukin-2 receptor subunit betatarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00242CladribinePurine nucleoside phosphorylasetarget
DB00242CladribineDNAtarget
DB00242CladribineDeoxycytidine kinaseenzyme
DB00242CladribineRibonucleoside-diphosphate reductase large subunittarget
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2target
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2 Btarget
DB00242CladribineDNA polymerase alpha catalytic subunittarget
DB00242CladribineDNA polymerase epsilon catalytic subunit Atarget
DB00242CladribineDNA polymerase epsilon subunit 2target
DB00242CladribineDNA polymerase epsilon subunit 3target
DB00242CladribineDNA polymerase epsilon subunit 4target
DB00242CladribineATP-binding cassette sub-family G member 2transporter
DB00242CladribineSolute carrier family 28 member 3transporter
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 2target
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 1target
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-1enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-6enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-9enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 2B7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-8enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-10enzyme
DB00688Mycophenolate mofetilLiver carboxylesterase 1enzyme
DB00688Mycophenolate mofetilCytochrome P450 3A4enzyme
DB00688Mycophenolate mofetilCytochrome P450 3A5enzyme
DB00688Mycophenolate mofetilCytochrome P450 2C8enzyme
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B1transporter
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B3transporter
DB00688Mycophenolate mofetilATP-binding cassette sub-family G member 2transporter
DB00688Mycophenolate mofetilP-glycoprotein 1transporter
DB00688Mycophenolate mofetil6-pyruvoyl tetrahydrobiopterin synthasetarget
DB00688Mycophenolate mofetilCarboxylic ester hydrolaseenzyme
DB00688Mycophenolate mofetilCanalicular multispecific organic anion transporter 1transporter
DB00864TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00864TacrolimusCytochrome P450 3A4enzyme
DB00864TacrolimusCytochrome P450 3A5enzyme
DB00864TacrolimusP-glycoprotein 1transporter
DB00864TacrolimusATP-binding cassette sub-family A member 5transporter
DB00864TacrolimusSerum albumincarrier
DB00864TacrolimusAlpha-1-acid glycoprotein 1carrier
DB00864TacrolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00877SirolimusCytochrome P450 3A4enzyme
DB00877SirolimusSerine/threonine-protein kinase mTORtarget
DB00877SirolimusFibroblast growth factor 2target
DB00877SirolimusCytochrome P450 3A5enzyme
DB00877SirolimusCytochrome P450 3A7enzyme
DB00877SirolimusP-glycoprotein 1transporter
DB00877SirolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusMultidrug and toxin extrusion protein 1transporter
DB00993AzathioprineHypoxanthine-guanine phosphoribosyltransferasetarget
DB00993AzathioprineThiopurine S-methyltransferaseenzyme
DB00993AzathioprineXanthine dehydrogenase/oxidaseenzyme
DB00993AzathioprineGlutathione S-transferase A1enzyme
DB00993AzathioprineGlutathione S-transferase A2enzyme
DB00993AzathioprineGlutathione S-transferase Mu 1enzyme
DB00993AzathioprineRas-related C3 botulinum toxin substrate 1target
DB00993AzathioprineCytochrome P450 1A2enzyme
DB01024Mycophenolic acidInosine-5'-monophosphate dehydrogenase 2target
DB01024Mycophenolic acidInosine-5'-monophosphate dehydrogenase 1target
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-1enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-9enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 2B7enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-7enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-6enzyme
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideDNAtarget
DB01041ThalidomideProtein cereblontarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB01097LeflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01097LeflunomideCytochrome P450 1A2enzyme
DB01097LeflunomideCytochrome P450 2C9enzyme
DB01097LeflunomideAryl hydrocarbon receptortarget
DB01097LeflunomideProtein-tyrosine kinase 2-betatarget
DB01097LeflunomideATP-binding cassette sub-family G member 2transporter
DB01281AbataceptT-lymphocyte activation antigen CD80target
DB01281AbataceptT-lymphocyte activation antigen CD86target
DB01590EverolimusSerine/threonine-protein kinase mTORtarget
DB01590EverolimusCytochrome P450 3A4enzyme
DB01590EverolimusSolute carrier organic anion transporter family member 1B1transporter
DB01590EverolimusSolute carrier organic anion transporter family member 1B3transporter
DB01590EverolimusSolute carrier organic anion transporter family member 1A2transporter
DB01590EverolimusCytochrome P450 2D6enzyme
DB06681BelataceptT-lymphocyte activation antigen CD86target
DB06681BelataceptT-lymphocyte activation antigen CD80target
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodCytochrome P450 4F12enzyme
DB08868FingolimodHistone deacetylase 1target
DB08879BelimumabTumor necrosis factor ligand superfamily member 13Btarget
DB08880TeriflunomideATP-binding cassette sub-family G member 2transporter
DB08880TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB08880TeriflunomideCytochrome P450 2C8enzyme
DB08880TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
DB08880TeriflunomideCytochrome P450 1A2enzyme
DB08904Certolizumab pegolTumor necrosis factortarget
DB08904Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
DB06168CanakinumabInterleukin-1 betatarget
DB09033VedolizumabIntegrin alpha-4target
DB09033VedolizumabIntegrin beta-7target
DB09036SiltuximabInterleukin-6target
DB09036SiltuximabCytochrome P450 3A4enzyme
DB11693VoclosporinCalcineurin subunit B type 1target
DB11693VoclosporinCalcineurin subunit B type 2target
DB06612MepolizumabInterleukin-5target
DB00441GemcitabineRibonucleoside-diphosphate reductase large subunittarget
DB00441GemcitabineUMP-CMP kinasetarget
DB00441GemcitabineThymidylate synthasetarget
DB00441GemcitabineCytidine deaminaseenzyme
DB00441GemcitabineDeoxycytidine kinaseenzyme
DB00441GemcitabineP-glycoprotein 1transporter
DB00441GemcitabineMultidrug resistance-associated protein 7transporter
DB00441GemcitabineEquilibrative nucleoside transporter 1transporter
DB00441GemcitabineDNAtarget
DB00441GemcitabineSodium/nucleoside cotransporter 1transporter
DB00441GemcitabineEquilibrative nucleoside transporter 2transporter
DB00441GemcitabineSolute carrier family 28 member 3transporter
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB00544FluorouracilThymidylate synthasetarget
DB00544FluorouracilCytochrome P450 1A2enzyme
DB00544FluorouracilThymidine phosphorylaseenzyme
DB00544FluorouracilSerum albumincarrier
DB00544FluorouracilCytochrome P450 2C9enzyme
DB00544FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
DB00544FluorouracilUridine phosphorylase 1enzyme
DB00544FluorouracilUridine phosphorylase 2enzyme
DB00544FluorouracilDNAtarget
DB00544FluorouracilRNAtarget
DB00544FluorouracilCytochrome P450 2A6enzyme
DB00544FluorouracilCytochrome P450 2C8enzyme
DB00544FluorouracilMethylenetetrahydrofolate reductaseenzyme
DB00544FluorouracilThymidylate synthaseenzyme
DB00544FluorouracilUridine 5'-monophosphate synthaseenzyme
DB00544FluorouracilAmidophosphoribosyltransferaseenzyme
DB00544FluorouracilSolute carrier family 22 member 7transporter
DB00544FluorouracilEquilibrative nucleoside transporter 1transporter
DB00544FluorouracilATP-binding cassette sub-family G member 2transporter
DB00544FluorouracilCanalicular multispecific organic anion transporter 2transporter
DB00544FluorouracilMultidrug resistance-associated protein 4transporter
DB00544FluorouracilMultidrug resistance-associated protein 5transporter
DB00544FluorouracilThyroxine-binding globulincarrier
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateP-glycoprotein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00563MethotrexateThymidylate synthasetarget
DB00563MethotrexateBifunctional purine biosynthesis protein PURHtarget
DB00563MethotrexateFolate receptor betatransporter
DB00563MethotrexateSolute carrier family 15 member 1transporter
DB00563MethotrexateProton-coupled amino acid transporter 1transporter
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DB00987CytarabineDNA polymerase betatarget
DB00987CytarabineCytidine deaminaseenzyme
DB00987CytarabineSolute carrier family 22 member 4transporter
DB00987CytarabineMultidrug resistance-associated protein 7transporter
DB00987CytarabineEquilibrative nucleoside transporter 1transporter
DB00987CytarabineDNAtarget
DB00987CytarabineCytochrome P450 3A4enzyme
DB00987CytarabineDeoxycytidine kinaseenzyme
DB00987Cytarabine5'-nucleotidaseenzyme
DB00987CytarabineDeoxycytidylate deaminaseenzyme
DB01008BusulfanDNAtarget
DB01008BusulfanCytochrome P450 3A4enzyme
DB01008BusulfanGlutathione S-transferase A2enzyme
DB01008BusulfanGlutathione S-transferase A1enzyme
DB01008BusulfanGlutathione S-transferase Mu 1enzyme
DB01008BusulfanGlutathione S-transferase Penzyme
DB01008BusulfanMicrosomal glutathione S-transferase 2enzyme
DB01033MercaptopurineThiopurine S-methyltransferaseenzyme
DB01033MercaptopurineXanthine dehydrogenase/oxidaseenzyme
DB01033MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
DB01033MercaptopurineSolute carrier family 22 member 8transporter
DB01033MercaptopurineMultidrug resistance-associated protein 4transporter
DB01033MercaptopurineMultidrug resistance-associated protein 5transporter
DB01033MercaptopurineSodium/nucleoside cotransporter 2transporter
DB01033MercaptopurineSolute carrier family 28 member 3transporter
DB01033MercaptopurineEquilibrative nucleoside transporter 1transporter
DB01033MercaptopurineEquilibrative nucleoside transporter 2transporter
DB01033MercaptopurineAldehyde oxidaseenzyme
DB01033MercaptopurineAmidophosphoribosyltransferasetarget
DB01033MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
DB01042MelphalanDNAtarget
DB01042MelphalanSolute carrier family 22 member 3transporter
DB01042MelphalanLarge neutral amino acids transporter small subunit 1transporter
DB01073FludarabineDNA polymerase alpha catalytic subunittarget
DB01073FludarabineRibonucleoside-diphosphate reductase large subunittarget
DB01073FludarabineEquilibrative nucleoside transporter 1transporter
DB01073FludarabineDNAtarget
DB01073FludarabineDeoxycytidine kinasetarget
DB01073FludarabineSolute carrier family 28 member 3transporter
DB04572ThiotepaCytochrome P450 2B6enzyme
DB04572ThiotepaCytochrome P450 3A4enzyme
DB04572ThiotepaDNAtarget
DB04572ThiotepaCholinesteraseenzyme
DB05259GlatiramerHLA class II histocompatibility antigen, DRB1-1 beta chaintarget
DB00026AnakinraInterleukin-1 receptor type 1target
DB00051AdalimumabTumor necrosis factortarget
DB00065InfliximabTumor necrosis factortarget
DB00087AlemtuzumabCAMPATH-1 antigentarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00087AlemtuzumabComplement C1r subcomponenttarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Atarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Btarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Ctarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00087AlemtuzumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00098Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD1atarget
DB00098Antithymocyte immunoglobulin (rabbit)Major histocompatibility complex class I-related gene proteintarget
DB00098Antithymocyte immunoglobulin (rabbit)Integrin alpha-Ltarget
DB00098Antithymocyte immunoglobulin (rabbit)T-lymphocyte activation antigen CD86target
DB00098Antithymocyte immunoglobulin (rabbit)Low affinity immunoglobulin gamma Fc region receptor II-btarget
DB00098Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD4target
DB00098Antithymocyte immunoglobulin (rabbit)Integrin beta-1target
DB00098Antithymocyte immunoglobulin (rabbit)Integrin alpha-Vtarget
DB00098Antithymocyte immunoglobulin (rabbit)Integrin beta-3target
DB00108NatalizumabIntegrin alpha-4target
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00108NatalizumabComplement C1r subcomponenttarget
DB00108NatalizumabComplement C1q subcomponent subunit Atarget
DB00108NatalizumabComplement C1q subcomponent subunit Btarget
DB00108NatalizumabComplement C1q subcomponent subunit Ctarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00108NatalizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00108NatalizumabIntercellular adhesion molecule 1target
DB00480LenalidomideProstaglandin G/H synthase 2target
DB00480LenalidomideTumor necrosis factor ligand superfamily member 11target
DB00480LenalidomideCadherin-5target
DB00480LenalidomideProtein cereblontarget
DB00480LenalidomideP-glycoprotein 1transporter
DB01257EculizumabComplement C5target
DB05679UstekinumabInterleukin-12 subunit betatarget
DB05679UstekinumabInterleukin-23target
DB06273TocilizumabInterleukin-6 receptor subunit alphatarget
DB06273TocilizumabCytochrome P450 3A4enzyme
DB06372RilonaceptInterleukin-1 betatarget
DB06372RilonaceptInterleukin-1 alphatarget
DB06372RilonaceptInterleukin-1 receptor antagonist proteintarget
DB06674GolimumabTumor necrosis factortarget
DB08895TofacitinibNon-receptor tyrosine-protein kinase TYK2target
DB08895TofacitinibCytochrome P450 3A4enzyme
DB08895TofacitinibCytochrome P450 2C19enzyme
DB08895TofacitinibTyrosine-protein kinase JAK2target
DB08895TofacitinibTyrosine-protein kinase JAK1target
DB08895TofacitinibTyrosine-protein kinase JAK3target
DB08895TofacitinibSerum albumincarrier
DB08910PomalidomideCytochrome P450 1A2enzyme
DB08910PomalidomideCytochrome P450 3A4enzyme
DB08910PomalidomideP-glycoprotein 1transporter
DB08910PomalidomideProtein cereblontarget
DB08910PomalidomideTumor necrosis factortarget
DB08910PomalidomideProstaglandin G/H synthase 2target
DB09029SecukinumabInterleukin-17Atarget
DB00056Gemtuzumab ozogamicinMyeloid cell surface antigen CD33target
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00056Gemtuzumab ozogamicinComplement C1r subcomponenttarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Atarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Btarget
DB00056Gemtuzumab ozogamicinComplement C1q subcomponent subunit Ctarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00056Gemtuzumab ozogamicinComplement C1s subcomponenttarget
DB00056Gemtuzumab ozogamicinHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00056Gemtuzumab ozogamicinLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00059PegaspargaseL-asparaginetarget
DB00059PegaspargaseThyroxine-binding globulincarrier
DB00073RituximabB-lymphocyte antigen CD20target
DB00078Ibritumomab tiuxetanB-lymphocyte antigen CD20target
DB00078Ibritumomab tiuxetanLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00078Ibritumomab tiuxetanComplement C1r subcomponenttarget
DB00078Ibritumomab tiuxetanComplement C1q subcomponent subunit Atarget
DB00078Ibritumomab tiuxetanComplement C1q subcomponent subunit Btarget
DB00078Ibritumomab tiuxetanComplement C1q subcomponent subunit Ctarget
DB00078Ibritumomab tiuxetanLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00078Ibritumomab tiuxetanComplement C1s subcomponenttarget
DB00078Ibritumomab tiuxetanHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00078Ibritumomab tiuxetanLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00078Ibritumomab tiuxetanLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00078Ibritumomab tiuxetanLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00081TositumomabB-lymphocyte antigen CD20target
DB00081TositumomabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00081TositumomabComplement C1r subcomponenttarget
DB00081TositumomabComplement C1q subcomponent subunit Atarget
DB00081TositumomabComplement C1q subcomponent subunit Btarget
DB00081TositumomabComplement C1q subcomponent subunit Ctarget
DB00081TositumomabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00081TositumomabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00081TositumomabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00081TositumomabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00081TositumomabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00120L-PhenylalanineTyrosine aminotransferasetarget
DB00120L-PhenylalanineLarge neutral amino acids transporter small subunit 2target
DB00120L-PhenylalaninePhenylalanine--tRNA ligase alpha subunittarget
DB00120L-PhenylalaninePhenylalanine-4-hydroxylasetarget
DB00120L-PhenylalaninePhenylalanine--tRNA ligase, mitochondrialtarget
DB00120L-PhenylalaninePhenylalanine--tRNA ligase beta subunittarget
DB00120L-PhenylalanineTyrosine 3-monooxygenasetarget
DB00120L-PhenylalanineMonocarboxylate transporter 10transporter
DB00262CarmustineGlutathione reductase, mitochondrialtarget
DB00262CarmustineDNAtarget
DB00262CarmustineRNAtarget
DB00276AmsacrineDNA topoisomerase 2-alphatarget
DB00276AmsacrineDNAtarget
DB00276AmsacrinePotassium voltage-gated channel subfamily H member 2target
DB00276AmsacrineP-glycoprotein 1transporter
DB00276AmsacrineAlpha-1-acid glycoprotein 1target
DB00276AmsacrineSerum albumintarget
DB00290BleomycinDNA ligase 3target
DB00290BleomycinDNA ligase 1target
DB00290BleomycinDNAtarget
DB00290BleomycinBleomycin hydrolaseenzyme
DB00291ChlorambucilDNAtarget
DB00291ChlorambucilGlutathione S-transferase Penzyme
DB00291ChlorambucilSolute carrier organic anion transporter family member 1A2transporter
DB00305MitomycinDNAtarget
DB00305MitomycinNADPH--cytochrome P450 reductaseenzyme
DB00309VindesineTubulin beta-1 chaintarget
DB00309VindesineCytochrome P450 3A4enzyme
DB00322FloxuridineThymidylate synthasetarget
DB00322FloxuridineThymidine phosphorylaseenzyme
DB00322FloxuridineCytochrome P450 2C9enzyme
DB00322FloxuridineThyroxine-binding globulincarrier
DB00352TioguanineDNAtarget
DB00352TioguanineMultidrug resistance-associated protein 4transporter
DB00352TioguanineHypoxanthine-guanine phosphoribosyltransferaseenzyme
DB00361VinorelbineTubulin beta chaintarget
DB00361VinorelbineCytochrome P450 3A4enzyme
DB00361VinorelbineP-glycoprotein 1transporter
DB00361VinorelbineCytochrome P450 2D6enzyme
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibP-glycoprotein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB00428StreptozocinDNAtarget
DB00428StreptozocinP-glycoprotein 1transporter
DB00428StreptozocinSolute carrier family 2, facilitated glucose transporter member 2target
DB00428StreptozocinO-GlcNAcase BT_4395target
DB00428StreptozocinCytochrome P450 1A1enzyme
DB00428StreptozocinCytochrome P450 1A2enzyme
DB00428StreptozocinCytochrome P450 2E1enzyme
DB00428StreptozocinBifunctional protein NCOATtarget
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneP-glycoprotein 1transporter
DB00443BetamethasoneCytochrome P450 19A1enzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00444TeniposideDNA topoisomerase 2-alphatarget
DB00444TeniposideCytochrome P450 2C19enzyme
DB00444TeniposideCytochrome P450 2C9enzyme
DB00444TeniposideCytochrome P450 3A4enzyme
DB00444TeniposideMultidrug resistance-associated protein 6transporter
DB00444TeniposideATP-binding cassette sub-family G member 2transporter
DB00444TeniposideCytochrome P450 3A5enzyme
DB00445EpirubicinChromodomain-helicase-DNA-binding protein 1target
DB00445EpirubicinDNA topoisomerase 2-alphatarget
DB00445EpirubicinDNAtarget
DB00445EpirubicinMultidrug resistance-associated protein 1transporter
DB00445EpirubicinUDP-glucuronosyltransferase 2B7enzyme
DB00445EpirubicinCytosolic phospholipase A2enzyme
DB00488AltretamineDNAtarget
DB00515CisplatinDNAtarget
DB00515CisplatinCanalicular multispecific organic anion transporter 2transporter
DB00515CisplatinMultidrug resistance-associated protein 5transporter
DB00515CisplatinCanalicular multispecific organic anion transporter 1transporter
DB00515CisplatinSolute carrier family 22 member 2transporter
DB00515CisplatinHigh affinity copper uptake protein 1transporter
DB00515CisplatinProbable low affinity copper uptake protein 2transporter
DB00515CisplatinMultidrug resistance-associated protein 6transporter
DB00515CisplatinP-glycoprotein 1transporter
DB00515CisplatinCopper-transporting ATPase 2transporter
DB00515CisplatinCopper-transporting ATPase 1transporter
DB00515CisplatinProstaglandin G/H synthase 2enzyme
DB00515CisplatinMyeloperoxidaseenzyme
DB00515CisplatinXanthine dehydrogenase/oxidaseenzyme
DB00515CisplatinArylamine N-acetyltransferaseenzyme
DB00515CisplatinCytochrome P450 2C9enzyme
DB00515CisplatinCytochrome P450 2B6enzyme
DB00515CisplatinCholinesteraseenzyme
DB00515CisplatinCytochrome P450 4A11enzyme
DB00515CisplatinATP-binding cassette sub-family G member 2transporter
DB00515CisplatinGlutathione S-transferase theta-1enzyme
DB00515CisplatinMetallothionein-1Aenzyme
DB00515CisplatinMetallothionein-2enzyme
DB00515CisplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00515CisplatinGlutathione S-transferase Penzyme
DB00515CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00515CisplatinGlutathione S-transferase Mu 1enzyme
DB00515CisplatinDNA-3-methyladenine glycosylasetarget
DB00515CisplatinAlpha-2-macroglobulintarget
DB00515CisplatinSerum albumincarrier
DB00515CisplatinSerotransferrintarget
DB00515CisplatinCopper transport protein ATOX1target
DB00526OxaliplatinDNAtarget
DB00526OxaliplatinSolute carrier family 22 member 2transporter
DB00526OxaliplatinHigh affinity copper uptake protein 1transporter
DB00526OxaliplatinSolute carrier family 22 member 3transporter
DB00526OxaliplatinATP-binding cassette sub-family G member 2transporter
DB00526OxaliplatinGlutathione S-transferase theta-1enzyme
DB00526OxaliplatinMetallothionein-1Aenzyme
DB00526OxaliplatinMetallothionein-2enzyme
DB00526OxaliplatinMyeloperoxidaseenzyme
DB00526OxaliplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00526OxaliplatinGlutathione S-transferase Penzyme
DB00526OxaliplatinGlutathione S-transferase Mu 1enzyme
DB00526OxaliplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00526OxaliplatinCanalicular multispecific organic anion transporter 1transporter
DB00526OxaliplatinCopper-transporting ATPase 2transporter
DB00526OxaliplatinCopper-transporting ATPase 1transporter
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DB00552PentostatinAdenosine deaminasetarget
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineP-glycoprotein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00570VinblastineSolute carrier organic anion transporter family member 1B1transporter
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBreakpoint cluster region proteintarget
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibP-glycoprotein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00631ClofarabineDNA polymerase alpha catalytic subunittarget
DB00631ClofarabineRibonucleoside-diphosphate reductase large subunittarget
DB00631ClofarabineDeoxycytidine kinaseenzyme
DB00631ClofarabineDNAtarget
DB00631ClofarabineATP-binding cassette sub-family G member 2transporter
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1target
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00642PemetrexedThymidylate synthasetarget
DB00642PemetrexedDihydrofolate reductasetarget
DB00642PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
DB00642PemetrexedDeoxycytidine kinaseenzyme
DB00642PemetrexedBifunctional purine biosynthesis protein PURHtarget
DB00642PemetrexedEquilibrative nucleoside transporter 1enzyme
DB00642PemetrexedSolute carrier family 22 member 8transporter
DB00687FludrocortisoneMineralocorticoid receptortarget
DB00687FludrocortisoneGlucocorticoid receptortarget
DB00687FludrocortisoneCytochrome P450 3A4enzyme
DB00687FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00687FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00687FludrocortisoneSerum albumincarrier
DB00687FludrocortisoneCorticosteroid-binding globulincarrier
DB00694DaunorubicinDNAtarget
DB00694DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DB00694DaunorubicinCytochrome P450 3A5enzyme
DB00694DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DB00694DaunorubicinP-glycoprotein 1transporter
DB00694DaunorubicinMultidrug resistance-associated protein 1transporter
DB00694DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DB00694DaunorubicinMultidrug resistance-associated protein 6transporter
DB00694DaunorubicinBile salt export pumptransporter
DB00694DaunorubicinMultidrug resistance-associated protein 7transporter
DB00694DaunorubicinATP-binding cassette sub-family G member 2transporter
DB00694DaunorubicinDNA topoisomerase 2-alphatarget
DB00694DaunorubicinDNA topoisomerase 2-betatarget
DB00694DaunorubicinCytochrome P450 1A1enzyme
DB00694DaunorubicinCytochrome P450 1B1enzyme
DB00694DaunorubicinCytochrome P450 3A4enzyme
DB00724ImiquimodToll-like receptor 7target
DB00724ImiquimodToll-like receptor 8target
DB00724ImiquimodCytochrome P450 3A4enzyme
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00741Hydrocortisone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00755TretinoinRetinoic acid receptor gammatarget
DB00755TretinoinRetinoic acid receptor RXR-betatarget
DB00755TretinoinRetinal dehydrogenase 1target
DB00755TretinoinRetinoic acid-induced protein 3target
DB00755TretinoinRetinoic acid receptor RXR-gammatarget
DB00755TretinoinNuclear receptor subfamily 0 group B member 1target
DB00755TretinoinRetinal dehydrogenase 2target
DB00755TretinoinRetinoic acid receptor responder protein 1target
DB00755TretinoinCytochrome P450 2C8enzyme
DB00755TretinoinCellular retinoic acid-binding protein 1transporter
DB00755TretinoinCellular retinoic acid-binding protein 2transporter
DB00755TretinoinCytochrome P450 2B6enzyme
DB00755TretinoinCytochrome P450 3A4enzyme
DB00755TretinoinCytochrome P450 3A5enzyme
DB00755TretinoinCytochrome P450 2A6enzyme
DB00755TretinoinCytochrome P450 3A7enzyme
DB00755TretinoinCytochrome P450 2C18enzyme
DB00755TretinoinCytochrome P450 2C9enzyme
DB00755TretinoinCytochrome P450 4A11enzyme
DB00755TretinoinCytochrome P450 1A1enzyme
DB00755TretinoinRetinoic acid receptor alphatarget
DB00755TretinoinRetinoic acid receptor betatarget
DB00755TretinoinLipocalin-1target
DB00755TretinoinOdorant-binding protein 2atarget
DB00755TretinoinRetinol-binding protein 4target
DB00755TretinoinSerum albumincarrier
DB00755Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
DB00755TretinoinRetinoic acid receptor RXR-alphatarget
DB00755TretinoinCytochrome P450 26A1target
DB00755TretinoinCytochrome P450 26B1target
DB00755TretinoinCytochrome P450 26C1target
DB00755TretinoinHematopoietic prostaglandin D synthasetarget
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanP-glycoprotein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideP-glycoprotein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00851DacarbazineDNA polymerase alpha subunit Btarget
DB00851DacarbazineCytochrome P450 1A1enzyme
DB00851DacarbazineCytochrome P450 1A2enzyme
DB00851DacarbazineCytochrome P450 2E1enzyme
DB00851Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00851DacarbazineDNAtarget
DB00853TemozolomideDNAtarget
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00888MechlorethamineDNAtarget
DB00888MechlorethamineCholinesteraseenzyme
DB00928AzacitidineDNA (cytosine-5)-methyltransferase 1target
DB00928AzacitidineCytidine deaminaseenzyme
DB00928AzacitidineDNAtarget
DB00928AzacitidineRNAtarget
DB00958CarboplatinDNAtarget
DB00958CarboplatinHigh affinity copper uptake protein 1transporter
DB00958CarboplatinProbable low affinity copper uptake protein 2transporter
DB00958CarboplatinXanthine dehydrogenase/oxidaseenzyme
DB00958CarboplatinMyeloperoxidaseenzyme
DB00958CarboplatinGlutathione S-transferase theta-1enzyme
DB00958CarboplatinMetallothionein-1Aenzyme
DB00958CarboplatinMetallothionein-2enzyme
DB00958CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00958CarboplatinGlutathione S-transferase Penzyme
DB00958CarboplatinGlutathione S-transferase Mu 1enzyme
DB00958CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00958CarboplatinCopper-transporting ATPase 1transporter
DB00958CarboplatinCopper-transporting ATPase 2transporter
DB00958CarboplatinATP-binding cassette sub-family G member 2transporter
DB00958CarboplatinCanalicular multispecific organic anion transporter 1transporter
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00970DactinomycinDNAtarget
DB00970DactinomycinSolute carrier family 22 member 5transporter
DB00970DactinomycinP-glycoprotein 1transporter
DB00970DactinomycinMultidrug resistance-associated protein 6transporter
DB00970DactinomycinMultidrug resistance-associated protein 1transporter
DB00970DactinomycinATP-binding cassette sub-family G member 2transporter
DB00970DactinomycinDNA topoisomerase 2target
DB00997DoxorubicinDNA topoisomerase 2-alphatarget
DB00997DoxorubicinDNAtarget
DB00997DoxorubicinCytochrome P450 3A4enzyme
DB00997DoxorubicinCytochrome P450 2D6enzyme
DB00997DoxorubicinCytochrome P450 2B6enzyme
DB00997DoxorubicinP-glycoprotein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DB00997DoxorubicinMultidrug resistance-associated protein 6transporter
DB00997DoxorubicinMultidrug resistance-associated protein 1transporter
DB00997DoxorubicinMultidrug resistance-associated protein 7transporter
DB00997DoxorubicinATP-binding cassette sub-family G member 2transporter
DB00997DoxorubicinBile salt export pumptransporter
DB00997DoxorubicinSolute carrier family 22 member 16transporter
DB00997DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DB00997DoxorubicinCytochrome P450 1B1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DB00997DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DB00997DoxorubicinAldo-keto reductase family 1 member C3enzyme
DB00997DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00997DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DB00997DoxorubicinNitric oxide synthase, endothelialenzyme
DB00997DoxorubicinNitric oxide synthase, inducibleenzyme
DB00997DoxorubicinNitric oxide synthase, brainenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DB00997DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DB00997DoxorubicinRalA-binding protein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DB00997DoxorubicinSerum albumincarrier
DB00997DoxorubicinNucleolar and coiled-body phosphoprotein 1target
DB01005HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
DB01005HydroxyureaCytochrome P450 2D6enzyme
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanP-glycoprotein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DB01030TopotecanMultidrug and toxin extrusion protein 1transporter
DB01030TopotecanMultidrug and toxin extrusion protein 2transporter
DB01101CapecitabineThymidylate synthasetarget
DB01101CapecitabineThymidine phosphorylaseenzyme
DB01101CapecitabineCytidine deaminaseenzyme
DB01101CapecitabineLiver carboxylesterase 1enzyme
DB01101CapecitabineDihydropyrimidine dehydrogenase [NADP(+)]enzyme
DB01101CapecitabineCytochrome P450 2C9enzyme
DB01101CapecitabineDNAtarget
DB01101CapecitabineRNAtarget
DB01168ProcarbazineDNAtarget
DB01168ProcarbazineXanthine dehydrogenase/oxidaseenzyme
DB01168ProcarbazineMonoamine oxidasetarget
DB01177IdarubicinDNA topoisomerase 2-alphatarget
DB01177IdarubicinDNAtarget
DB01177IdarubicinMultidrug resistance-associated protein 1transporter
DB01177IdarubicinCytochrome P450 2C9enzyme
DB01177IdarubicinCytochrome P450 2D6enzyme
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB01196EstramustineEstrogen receptor betatarget
DB01196EstramustineEstrogen receptor alphatarget
DB01196EstramustineMicrotubule-associated protein 2target
DB01196EstramustineMicrotubule-associated protein 1Atarget
DB01196EstramustineP-glycoprotein 1transporter
DB01196EstramustineCytochrome P450 3A4enzyme
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneP-glycoprotein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneDNAtarget
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB01206LomustineDNAtarget
DB01206LomustineCytochrome P450 3A4enzyme
DB01206LomustineCytochrome P450 2D6enzyme
DB01206LomustineStathmin-4target
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB01229PaclitaxelApoptosis regulator Bcl-2target
DB01229PaclitaxelTubulin beta-1 chaintarget
DB01229PaclitaxelCytochrome P450 2C8enzyme
DB01229PaclitaxelCytochrome P450 3A4enzyme
DB01229PaclitaxelCytochrome P450 3A5enzyme
DB01229PaclitaxelCytochrome P450 3A7enzyme
DB01229PaclitaxelBile salt export pumptransporter
DB01229PaclitaxelP-glycoprotein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 7transporter
DB01229PaclitaxelCytochrome P450 19A1enzyme
DB01229PaclitaxelCytochrome P450 1B1enzyme
DB01229PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
DB01229PaclitaxelNuclear receptor subfamily 1 group I member 2target
DB01229PaclitaxelMicrotubule-associated protein 4target
DB01229PaclitaxelMicrotubule-associated protein 2target
DB01229PaclitaxelMicrotubule-associated protein tautarget
DB01229PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01248DocetaxelApoptosis regulator Bcl-2target
DB01248DocetaxelTubulin beta-1 chaintarget
DB01248DocetaxelCytochrome P450 3A4enzyme
DB01248DocetaxelCytochrome P450 3A5enzyme
DB01248DocetaxelCytochrome P450 3A7enzyme
DB01248DocetaxelP-glycoprotein 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 7transporter
DB01248DocetaxelCytochrome P450 1B1enzyme
DB01248DocetaxelMicrotubule-associated protein 2target
DB01248DocetaxelMicrotubule-associated protein 4target
DB01248DocetaxelMicrotubule-associated protein tautarget
DB01248DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DB01248DocetaxelSolute carrier family 22 member 7transporter
DB01248DocetaxelATP-binding cassette sub-family G member 2transporter
DB01248DocetaxelCanalicular multispecific organic anion transporter 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 1transporter
DB01248DocetaxelNuclear receptor subfamily 1 group I member 2target
DB01254DasatinibTyrosine-protein kinase ABL1target
DB01254DasatinibAbelson tyrosine-protein kinase 2target
DB01254DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DB01254DasatinibTyrosine-protein kinase Fyntarget
DB01254DasatinibTyrosine-protein kinase Lcktarget
DB01254DasatinibTyrosine-protein kinase Yestarget
DB01254DasatinibMast/stem cell growth factor receptor Kittarget
DB01254DasatinibPlatelet-derived growth factor receptor betatarget
DB01254DasatinibEphrin type-A receptor 2target
DB01254DasatinibSignal transducer and activator of transcription 5Btarget
DB01254DasatinibCytochrome P450 3A4enzyme
DB01254DasatinibP-glycoprotein 1transporter
DB01254DasatinibATP-binding cassette sub-family G member 2transporter
DB01254DasatinibCytochrome P450 1A1enzyme
DB01254DasatinibCytochrome P450 1A2enzyme
DB01254DasatinibCytochrome P450 1B1enzyme
DB01254DasatinibCytochrome P450 3A5enzyme
DB01254DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01254DasatinibTyrosine-protein kinase BTKtarget
DB01254DasatinibNuclear receptor subfamily 4 group A member 3target
DB01254DasatinibBreakpoint cluster region proteintarget
DB01254DasatinibTyrosine-protein kinase CSKtarget
DB01254DasatinibEphrin type-A receptor 5target
DB01254DasatinibEphrin type-B receptor 4target
DB01254DasatinibTyrosine-protein kinase Fgrtarget
DB01254DasatinibTyrosine-protein kinase FRKtarget
DB01254DasatinibHeat shock cognate 71 kDa proteintarget
DB01254DasatinibTyrosine-protein kinase Lyntarget
DB01254DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DB01254DasatinibMitogen-activated protein kinase 14target
DB01254DasatinibAmidophosphoribosyltransferasetarget
DB01268SunitinibPlatelet-derived growth factor receptor betatarget
DB01268SunitinibVascular endothelial growth factor receptor 1target
DB01268SunitinibVascular endothelial growth factor receptor 2target
DB01268SunitinibVascular endothelial growth factor receptor 3target
DB01268SunitinibMast/stem cell growth factor receptor Kittarget
DB01268SunitinibReceptor-type tyrosine-protein kinase FLT3target
DB01268SunitinibMacrophage colony-stimulating factor 1 receptortarget
DB01268SunitinibPlatelet-derived growth factor receptor alphatarget
DB01268SunitinibCytochrome P450 3A4enzyme
DB01268SunitinibCytochrome P450 3A5enzyme
DB01268SunitinibCytochrome P450 3A7enzyme
DB01268SunitinibMultidrug resistance-associated protein 4transporter
DB01268SunitinibP-glycoprotein 1transporter
DB01268SunitinibCanalicular multispecific organic anion transporter 1transporter
DB01268SunitinibATP-binding cassette sub-family G member 2transporter
DB01280NelarabineDNAtarget
DB01280NelarabineAdenosine deaminaseenzyme
DB01280NelarabineDeoxycytidine kinaseenzyme
DB01280NelarabineDeoxyguanosine kinase, mitochondrialenzyme
DB01280NelarabineDNA polymerase alpha catalytic subunittarget
DB01285CorticotropinAdrenocorticotropic hormone receptortarget
DB01285CorticotropinCorticoliberintarget
DB01285Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB01285Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB01285Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB01285CorticotropinCytochrome P450 3A4enzyme
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB04868NilotinibTyrosine-protein kinase ABL1target
DB04868NilotinibMast/stem cell growth factor receptor Kittarget
DB04868NilotinibCytochrome P450 2D6enzyme
DB04868NilotinibCytochrome P450 2C8enzyme
DB04868NilotinibCytochrome P450 2C9enzyme
DB04868NilotinibCytochrome P450 3A4enzyme
DB04868NilotinibP-glycoprotein 1transporter
DB04868NilotinibATP-binding cassette sub-family G member 2transporter
DB04868NilotinibUDP-glucuronosyltransferase 1-1transporter
DB04868NilotinibCytochrome P450 2B6enzyme
DB04868NilotinibSolute carrier organic anion transporter family member 1B1transporter
DB05109TrabectedinCytochrome P450 3A4enzyme
DB05109TrabectedinCytochrome P450 2C9enzyme
DB05109TrabectedinCytochrome P450 2D6enzyme
DB05109TrabectedinCytochrome P450 2E1enzyme
DB05109TrabectedinCytochrome P450 2C19enzyme
DB05109TrabectedinDNAtarget
DB05109TrabectedinProstaglandin G/H synthase 1enzyme
DB05773Trastuzumab emtansineReceptor tyrosine-protein kinase erbB-2target
DB05773Trastuzumab emtansineP-glycoprotein 1transporter
DB05773Trastuzumab emtansineCytochrome P450 3A4enzyme
DB05773Trastuzumab emtansineCytochrome P450 3A5enzyme
DB06287TemsirolimusSerine/threonine-protein kinase mTORtarget
DB06287TemsirolimusCytochrome P450 3A4enzyme
DB06287TemsirolimusCytochrome P450 3A5enzyme
DB06287TemsirolimusCytochrome P450 3A7enzyme
DB06287TemsirolimusCytochrome P450 2D6enzyme
DB06287TemsirolimusP-glycoprotein 1transporter
DB06589PazopanibVascular endothelial growth factor receptor 1target
DB06589PazopanibVascular endothelial growth factor receptor 2target
DB06589PazopanibVascular endothelial growth factor receptor 3target
DB06589PazopanibPlatelet-derived growth factor receptor alphatarget
DB06589PazopanibPlatelet-derived growth factor receptor betatarget
DB06589PazopanibMast/stem cell growth factor receptor Kittarget
DB06589PazopanibCytochrome P450 3A4enzyme
DB06589PazopanibCytochrome P450 2D6enzyme
DB06589PazopanibCytochrome P450 2C8enzyme
DB06589PazopanibCytochrome P450 1A2enzyme
DB06589PazopanibP-glycoprotein 1transporter
DB06589PazopanibATP-binding cassette sub-family G member 2transporter
DB06589PazopanibSolute carrier organic anion transporter family member 1B1transporter
DB06589PazopanibUDP-glucuronosyltransferase 1-1transporter
DB06589PazopanibFibroblast growth factor receptor 3target
DB06589PazopanibTyrosine-protein kinase ITK/TSKtarget
DB06589PazopanibFibroblast growth factor 1target
DB06589PazopanibSH2B adapter protein 3target
DB06603PanobinostatCytochrome P450 2D6enzyme
DB06603PanobinostatCytochrome P450 3A4enzyme
DB06603PanobinostatP-glycoprotein 1transporter
DB06603PanobinostatHistone deacetylasetarget
DB06772CabazitaxelCytochrome P450 3A4enzyme
DB06772CabazitaxelCytochrome P450 3A5enzyme
DB06772CabazitaxelCytochrome P450 2C8enzyme
DB06772CabazitaxelP-glycoprotein 1transporter
DB06772CabazitaxelATP-binding cassette sub-family G member 2transporter
DB06772CabazitaxelTubulin alpha-4A chaintarget
DB06772CabazitaxelTubulin beta-1 chaintarget
DB06772CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
DB06772CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
DB06813PralatrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB06813PralatrexateDihydrofolate reductasetarget
DB06813PralatrexateThymidylate synthasetarget
DB06813PralatrexateFolate transporter 1transporter
DB08870Brentuximab vedotinTumor necrosis factor receptor superfamily member 8target
DB08870Brentuximab vedotinCytochrome P450 3A4enzyme
DB08870Brentuximab vedotinATP-binding cassette sub-family B member 5transporter
DB08877RuxolitinibTyrosine-protein kinase JAK1target
DB08877RuxolitinibTyrosine-protein kinase JAK2target
DB08877RuxolitinibCytochrome P450 3A4enzyme
DB08935ObinutuzumabB-lymphocyte antigen CD20target
DB09052BlinatumomabB-lymphocyte antigen CD19target
DB09052BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
DB09053IbrutinibTyrosine-protein kinase BTKtarget
DB09053IbrutinibCytochrome P450 3A4enzyme
DB09053IbrutinibCytochrome P450 3A5enzyme
DB09053IbrutinibSerum albumincarrier
DB09053Ibrutinibalpha1-acid glycoproteincarrier
DB09053IbrutinibCytochrome P450 2D6enzyme
DB09054IdelalisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB09054IdelalisibATP-binding cassette sub-family G member 2transporter
DB09054IdelalisibP-glycoprotein 1transporter
DB09054IdelalisibAldehyde oxidaseenzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1-4enzyme
DB09054IdelalisibCytochrome P450 2C8enzyme
DB09054IdelalisibCytochrome P450 2C19enzyme
DB09054IdelalisibCytochrome P450 2B6enzyme
DB09054IdelalisibCytochrome P450 3A4enzyme
DB09054IdelalisibSolute carrier organic anion transporter family member 1B1transporter
DB09054IdelalisibSolute carrier organic anion transporter family member 1B3transporter
DB09054IdelalisibCytochrome P450 3A5enzyme
DB09054IdelalisibCytochrome P450 3A43enzyme
DB09054IdelalisibCytochrome P450 3A7enzyme
DB09073PalbociclibCyclin-dependent kinase 4target
DB09073PalbociclibCyclin-dependent kinase 6target
DB09073PalbociclibCytochrome P450 3A4enzyme
DB09073PalbociclibBile salt sulfotransferaseenzyme
DB09073PalbociclibP-glycoprotein 1transporter
DB09073PalbociclibATP-binding cassette sub-family G member 2transporter
DB09073PalbociclibSerum albumincarrier
DB09073PalbociclibSolute carrier family 22 member 1transporter
DB09077DinutuximabGanglioside GD2target
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB00222GlimepirideATP-sensitive inward rectifier potassium channel 1target
DB00222GlimepirideATP-sensitive inward rectifier potassium channel 11target
DB00222GlimepirideCytochrome P450 2C9enzyme
DB00222GlimepirideATP-binding cassette sub-family C member 8target
DB00222GlimepirideBile salt export pumptransporter
DB00337PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00337PimecrolimusSerine/threonine-protein kinase mTORtarget
DB00337PimecrolimusCytochrome P450 3A4enzyme
DB01816CastanospermineGlucan 1,3-beta-glucosidasetarget
DB04258SeocalcitolVitamin D3 receptortarget
DB05260Gallium nitrateSerotransferrincarrier
DB05260Gallium nitrateRibonucleoside-diphosphate reductase subunit M2target
DB05260Gallium nitrateProtein-tyrosine-phosphatasetarget
DB05260Gallium nitrateInterleukin-1 betatarget
DB05260Gallium nitrateHydroxylapatitetarget
DB05260Gallium nitrateOsteocalcintarget
DB05260Gallium nitrateV-type proton ATPase subunit B, brain isoformtarget
DB05260Gallium nitrateTransferrin receptortransporter
DB08908Dimethyl fumarateKelch-like ECH-associated protein 1target
DB08908Dimethyl fumarateTranscription factor p65target
DB11921DeflazacortCytochrome P450 3A4enzyme
DB11921DeflazacortGlucocorticoid receptortarget
DB11921DeflazacortCytochrome P450 3A5enzyme
DB13014HypericinSerum albumincarrier
DB13014HypericinGlutathione S-transferase A1target
DB13014HypericinGlutathione S-transferase Ptarget
DB00092AlefaceptT-cell surface antigen CD2target
DB00092AlefaceptLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00092AlefaceptComplement C1r subcomponenttarget
DB00092AlefaceptComplement C1q subcomponent subunit Atarget
DB00092AlefaceptComplement C1q subcomponent subunit Btarget
DB00092AlefaceptComplement C1q subcomponent subunit Ctarget
DB00092AlefaceptLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00092AlefaceptHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00092AlefaceptLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00092AlefaceptLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00092AlefaceptLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00095EfalizumabIntegrin alpha-Ltarget
DB00095EfalizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00095EfalizumabComplement C1r subcomponenttarget
DB00095EfalizumabComplement C1q subcomponent subunit Atarget
DB00095EfalizumabComplement C1q subcomponent subunit Btarget
DB00095EfalizumabComplement C1q subcomponent subunit Ctarget
DB00095EfalizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00095EfalizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00095EfalizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00095EfalizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00095EfalizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB04951PirfenidoneFurintarget
DB04951PirfenidoneCytochrome P450 1A2enzyme
DB04956AfelimomabTumor necrosis factortarget
DB05676ApremilastPhosphodiesterase isozyme 4target
DB05676ApremilastCytochrome P450 3A4enzyme
DB05676ApremilastCytochrome P450 2A6enzyme
DB05676ApremilastCytochrome P450 1A2enzyme
DB05676ApremilastP-glycoprotein 1transporter
DB08059WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB08059WortmanninSerine/threonine-protein kinase PLK1target
DB08059WortmanninPhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB08059WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00018Interferon alfa-n3Interferon alpha/beta receptor 1target
DB00018Interferon alfa-n3Interferon alpha/beta receptor 2target
DB00018Interferon alfa-n3Cytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2C9enzyme
DB00041AldesleukinInterleukin-2 receptor subunit betatarget
DB00041AldesleukinInterleukin-2 receptor subunit alphatarget
DB00041AldesleukinCytokine receptor common subunit gammatarget
DB00041AldesleukinProstaglandin G/H synthase 2enzyme
DB00041AldesleukinCytosolic phospholipase A2enzyme
DB00041AldesleukinCytochrome P450 3A4enzyme
DB00041AldesleukinXanthine dehydrogenase/oxidaseenzyme
DB00041AldesleukinCytochrome P450 2E1enzyme
DB00069Interferon alfacon-1Interferon alpha/beta receptor 1target
DB00069Interferon alfacon-1Interferon alpha/beta receptor 2target
DB00069Interferon alfacon-1Cytochrome P450 1A2enzyme
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00112BevacizumabComplement C1r subcomponenttarget
DB00112BevacizumabComplement C1q subcomponent subunit Atarget
DB00112BevacizumabComplement C1q subcomponent subunit Btarget
DB00112BevacizumabComplement C1q subcomponent subunit Ctarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00112BevacizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00112BevacizumabVascular endothelial growth factor Atarget
DB00188BortezomibCytochrome P450 3A4enzyme
DB00188BortezomibCytochrome P450 2C19enzyme
DB00188BortezomibCytochrome P450 1A2enzyme
DB00188BortezomibCytochrome P450 2D6enzyme
DB00188BortezomibCytochrome P450 2C9enzyme
DB00188BortezomibProteasome subunit beta type-5target
DB00188BortezomibProteasome subunit beta type-1target
DB00293RaltitrexedThymidylate synthasetarget
DB00293RaltitrexedFolylpolyglutamate synthase, mitochondrialtarget
DB00307BexaroteneRetinoic acid receptor RXR-betatarget
DB00307BexaroteneCytochrome P450 3A4enzyme
DB00307BexaroteneRetinoic acid receptor RXR-alphatarget
DB00307BexaroteneRetinoic acid receptor RXR-gammatarget
DB00307BexaroteneCytochrome P450 2C8enzyme
DB00380DexrazoxaneDNA topoisomerase 2-alphatarget
DB00380DexrazoxaneDNA topoisomerase 2-betatarget
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00495ZidovudineSerum albumincarrier
DB00495ZidovudineCytochrome P450 2A6enzyme
DB00495ZidovudineCytochrome P450 2C9enzyme
DB00495ZidovudineCytochrome P450 3A4enzyme
DB00495ZidovudineReverse transcriptase/RNaseHtarget
DB00495ZidovudineSolute carrier family 22 member 2transporter
DB00495ZidovudineSolute carrier family 22 member 6transporter
DB00495ZidovudineSolute carrier family 22 member 7transporter
DB00495ZidovudineSolute carrier family 22 member 8transporter
DB00495ZidovudineSolute carrier family 22 member 11transporter
DB00495ZidovudineSodium/nucleoside cotransporter 1transporter
DB00495ZidovudineEquilibrative nucleoside transporter 2transporter
DB00495ZidovudineP-glycoprotein 1transporter
DB00495ZidovudineMultidrug resistance-associated protein 4transporter
DB00495ZidovudineMultidrug resistance-associated protein 5transporter
DB00495ZidovudineATP-binding cassette sub-family G member 2transporter
DB00495ZidovudineTelomerase reverse transcriptasetarget
DB00495ZidovudineThymidine kinase, cytosolicenzyme
DB00495ZidovudineUDP-glucuronosyltransferase 2B7enzyme
DB00495ZidovudineUDP-glucuronosyltransferase 1-1enzyme
DB00550PropylthiouracilThyroid peroxidasetarget
DB00550PropylthiouracilMyeloperoxidaseenzyme
DB00550PropylthiouracilDopamine beta-hydroxylaseenzyme
DB00550PropylthiouracilCytochrome P450 1A1enzyme
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB00601Linezolid23S ribosomal RNAtarget
DB00601LinezolidAmine oxidase [flavin-containing] Aenzyme
DB00601LinezolidAmine oxidase [flavin-containing] Benzyme
DB00763MethimazoleThyroid peroxidasetarget
DB00763MethimazoleCytochrome P450 1A2enzyme
DB00763MethimazoleCytochrome P450 2A6enzyme
DB00763MethimazoleCytochrome P450 2B6enzyme
DB00763MethimazoleCytochrome P450 2C19enzyme
DB00763MethimazoleCytochrome P450 2C9enzyme
DB00763MethimazoleCytochrome P450 2D6enzyme
DB00763MethimazoleCytochrome P450 2E1enzyme
DB00763MethimazoleCytochrome P450 3A4enzyme
DB00763MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01099FlucytosineThymidylate synthasetarget
DB01099FlucytosineDNA (cytosine-5)-methyltransferase 1target
DB01099FlucytosineDNAtarget
DB01169Arsenic trioxideInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB01169Arsenic trioxideTranscription factor AP-1target
DB01169Arsenic trioxideG1/S-specific cyclin-D1target
DB01169Arsenic trioxideMitogen-activated protein kinase 3target
DB01169Arsenic trioxideMitogen-activated protein kinase 1target
DB01169Arsenic trioxideRAC-alpha serine/threonine-protein kinasetarget
DB01169Arsenic trioxideCanalicular multispecific organic anion transporter 1transporter
DB01169Arsenic trioxideThioredoxin reductase 1, cytoplasmictarget
DB01169Arsenic trioxideP-glycoprotein 1transporter
DB01169Arsenic trioxideCytochrome P450 3A4enzyme
DB01169Arsenic trioxideCyclin-dependent kinase inhibitor 1target
DB01169Arsenic trioxideHistone deacetylase 1target
DB01169Arsenic trioxideProtein PMLtarget
DB01169Arsenic trioxideSerum albumincarrier
DB01262DecitabineDNAtarget
DB01262DecitabineDNA (cytosine-5)-methyltransferase 1target
DB01262DecitabineDeoxycytidine kinaseenzyme
DB02546VorinostatHistone deacetylase 1target
DB02546VorinostatHistone deacetylase 2target
DB02546VorinostatHistone deacetylase 3target
DB02546VorinostatHistone deacetylase 6target
DB02546VorinostatHistone deacetylase 8target
DB02546VorinostatAcetoin utilization proteintarget
DB04845IxabepiloneTubulin beta-3 chaintarget
DB04845IxabepiloneCytochrome P450 3A4enzyme
DB05015BelinostatHistone deacetylasetarget
DB05015BelinostatCytochrome P450 1A2enzyme
DB05015BelinostatUDP-glucuronosyltransferase 1-4enzyme
DB05015BelinostatCytochrome P450 2C8enzyme
DB05015BelinostatCytochrome P450 2C9enzyme
DB05015BelinostatP-glycoprotein 1transporter
DB06616BosutinibBreakpoint cluster region proteintarget
DB06616BosutinibTyrosine-protein kinase ABL1target
DB06616BosutinibTyrosine-protein kinase Lyntarget
DB06616BosutinibTyrosine-protein kinase HCKtarget
DB06616BosutinibProto-oncogene tyrosine-protein kinase Srctarget
DB06616BosutinibP-glycoprotein 1transporter
DB06616BosutinibCytochrome P450 3A4enzyme
DB06616BosutinibCyclin-dependent kinase 2target
DB06616BosutinibDual specificity mitogen-activated protein kinase kinase 1target
DB06616BosutinibDual specificity mitogen-activated protein kinase kinase 2target
DB06616BosutinibMitogen-activated protein kinase kinase kinase 2target
DB06616BosutinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
DB06616BosutinibCytochrome P450 2C8enzyme
DB06769BendamustineCytochrome P450 1A2enzyme
DB08871EribulinApoptosis regulator Bcl-2target
DB08871EribulinTubulin beta-1 chaintarget
DB08889CarfilzomibP-glycoprotein 1transporter
DB08889CarfilzomibProteasome subunit beta type-5target
DB08889CarfilzomibProteasome subunit beta type-9target
DB08889CarfilzomibProteasome subunit beta type-10target
DB08889CarfilzomibProteasome subunit beta type-8target
DB08889CarfilzomibProteasome subunit beta type-1target
DB08889CarfilzomibProteasome subunit beta type-2target
DB08901PonatinibTyrosine-protein kinase ABL1target
DB08901PonatinibBreakpoint cluster region proteintarget
DB08901PonatinibMast/stem cell growth factor receptor Kittarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB08901PonatinibAngiopoietin-1 receptortarget
DB08901PonatinibReceptor-type tyrosine-protein kinase FLT3target
DB08901PonatinibCytochrome P450 3A4enzyme
DB08901PonatinibCytochrome P450 2C8enzyme
DB08901PonatinibCytochrome P450 2D6enzyme
DB08901PonatinibCytochrome P450 3A5enzyme
DB08901PonatinibP-glycoprotein 1transporter
DB08901PonatinibATP-binding cassette sub-family G member 2transporter
DB08901PonatinibFibroblast growth factor receptor 1target
DB08901PonatinibFibroblast growth factor receptor 2target
DB08901PonatinibFibroblast growth factor receptor 3target
DB08901PonatinibFibroblast growth factor receptor 4target
DB08901PonatinibTyrosine-protein kinase Lcktarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase Srctarget
DB08901PonatinibTyrosine-protein kinase Lyntarget
DB08901PonatinibVascular endothelial growth factor receptor 2target
DB08901PonatinibPlatelet-derived growth factor receptor alphatarget
DB09074OlaparibPoly [ADP-ribose] polymerase 1target
DB09074OlaparibCytochrome P450 3A4enzyme
DB09074OlaparibCytochrome P450 2B6enzyme
DB09074OlaparibPoly [ADP-ribose] polymerase 2target
DB09074OlaparibPoly [ADP-ribose] polymerase 3target
DB09074OlaparibCytochrome P450 3A5enzyme
DB09074OlaparibP-glycoprotein 1transporter
DB09074OlaparibATP-binding cassette sub-family G member 2transporter
DB11767SarilumabAlanine aminotransferase 1enzyme
DB11767SarilumabAlanine aminotransferase 2enzyme
DB11767SarilumabAspartate aminotransferaseenzyme
DB11767SarilumabCytochrome P450 3A4enzyme
DB11767SarilumabInterleukin-6 receptor subunit alphatarget
DB11767SarilumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB11767SarilumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB11767SarilumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB11767SarilumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB11767SarilumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB05459BriakinumabInterleukin-12 subunit betatarget
DB05459BriakinumabInterleukin-23 subunit alphatarget
DB14066TetrandrineP-glycoprotein 1target
DB14066TetrandrineCytochrome P450 3A4enzyme
DB00795SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
DB00795SulfasalazineCystine/glutamate transportertarget
DB00795SulfasalazineATP-binding cassette sub-family G member 2transporter
DB00795SulfasalazineCanalicular multispecific organic anion transporter 1transporter
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00795SulfasalazineProstaglandin G/H synthase 2target
DB00795SulfasalazinePeroxisome proliferator-activated receptor gammatarget
DB00795SulfasalazineProstaglandin G/H synthase 1target
DB00795SulfasalazineArachidonate 5-lipoxygenasetarget
DB00795SulfasalazineProton-coupled folate transportertransporter
DB00795SulfasalazineThromboxane-A synthasetarget
DB00795SulfasalazinePhospholipase A2target
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineP-glycoprotein 1transporter
DB01611HydroxychloroquineSerum albumincarrier
DB01611Hydroxychloroquinealpha1-acid glycoproteincarrier
DB01611HydroxychloroquineCytochrome P450 3A4enzyme
DB01611HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
DB00432TrifluridineThymidylate synthasetarget
DB00432TrifluridineDNAtarget
DB00432TrifluridineThymidine kinase, cytosolicenzyme
DB00432TrifluridineThymidine phosphorylaseenzyme
DB00432TrifluridineSolute carrier family 22 member 6transporter
DB00432TrifluridineSodium/nucleoside cotransporter 1transporter
DB00432TrifluridineEquilibrative nucleoside transporter 1transporter
DB00432TrifluridineEquilibrative nucleoside transporter 2transporter
DB00432TrifluridineSerum albumincarrier
DB04630AldosteroneMineralocorticoid receptortarget
DB04630AldosteroneP-glycoprotein 1transporter
DB04630AldosteroneSolute carrier family 22 member 5transporter
DB04630AldosteroneSolute carrier organic anion transporter family member 1A2transporter
DB04630AldosteroneCytochrome P450 11B1, mitochondrialenzyme
DB04630AldosteroneCytochrome P450 11B2, mitochondrialenzyme
DB04630AldosteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB04630AldosteroneGlucocorticoid receptortarget
DB04630AldosteroneCytochrome P450 3A4enzyme
DB01108Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB01108Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
DB01108TrilostaneEstrogen receptor betatarget
DB01108TrilostaneEstrogen receptor alphatarget
DB01108TrilostaneCytochrome P450 3A4enzyme
DB13208PrednylideneCytochrome P450 3A4enzyme
DB13208PrednylideneCytochrome P450 3A5enzyme
DB01384ParamethasoneCorticosteroid-binding globulincarrier
DB01384ParamethasoneGlucocorticoid receptortarget
DB01384ParamethasoneCytochrome P450 3A4enzyme
DB01384ParamethasoneCytochrome P450 3A5enzyme
DB09383MeprednisoneSerum albumincarrier
DB09383MeprednisoneCytochrome P450 3A4enzyme
DB09383MeprednisoneCytochrome P450 3A5enzyme
DB11529MelengestrolCytochrome P450 3A4enzyme
DB09378FluprednisoloneCytochrome P450 3A4enzyme
DB00180FlunisolideCorticosteroid-binding globulincarrier
DB00180FlunisolideGlucocorticoid receptortarget
DB00180FlunisolideCytochrome P450 3A4enzyme
DB13003CortivazolGlucocorticoid receptortarget
DB13003CortivazolCytochrome P450 3A4enzyme
DB13003CortivazolCytochrome P450 3A5enzyme
DB13843CloprednolCytochrome P450 3A4enzyme
DB13843CloprednolCytochrome P450 3A5enzyme
DB00240AlclometasoneCorticosteroid-binding globulincarrier
DB00240AlclometasoneGlucocorticoid receptortarget
DB00240AlclometasoneCytochrome P450 3A4enzyme
DB00288AmcinonideGlucocorticoid receptortarget
DB00288AmcinonideAnnexin A1target
DB00288AmcinonideCytochrome P450 3A4enzyme
DB00288AmcinonideCytochrome P450 3A5enzyme
DB01410CiclesonideCorticosteroid-binding globulincarrier
DB01410CiclesonideCytochrome P450 3A4enzyme
DB01410CiclesonideCytochrome P450 2D6enzyme
DB01410CiclesonideGlucocorticoid receptortarget
DB01410CiclesonideLiver carboxylesterase 1enzyme
DB11750ClobetasolCytochrome P450 3A4enzyme
DB11750ClobetasolCytochrome P450 3A5enzyme
DB01013Clobetasol propionateGlucocorticoid receptortarget
DB01013Clobetasol propionateCytochrome P450 3A4enzyme
DB01013Clobetasol propionateCytochrome P450 3A5enzyme
DB13158ClobetasoneGlucocorticoid receptortarget
DB13158ClobetasoneCytochrome P450 3A4enzyme
DB00838ClocortoloneGlucocorticoid receptortarget
DB01260DesonideGlucocorticoid receptortarget
DB01260DesonideCytochrome P450 3A4enzyme
DB00547DesoximetasoneGlucocorticoid receptortarget
DB11487Dexamethasone isonicotinateCytochrome P450 3A4enzyme
DB11487Dexamethasone isonicotinateCytochrome P450 3A5enzyme
DB00223DiflorasoneGlucocorticoid receptortarget
DB09095DifluocortoloneAnnexin A3target
DB09095DifluocortoloneGlucocorticoid receptortarget
DB09095DifluocortoloneCytochrome P450 3A4enzyme
DB09095DifluocortoloneCytochrome P450 3A5enzyme
DB06781DifluprednateGlucocorticoid receptortarget
DB06781DifluprednateCytochrome P450 3A4enzyme
DB00663FlumethasoneCorticosteroid-binding globulincarrier
DB00663FlumethasoneGlucocorticoid receptortarget
DB00663FlumethasoneCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideCorticosteroid-binding globulincarrier
DB00591Fluocinolone acetonideGlucocorticoid receptortarget
DB00591Fluocinolone acetonideCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideAnnexin A1target
DB00591Fluocinolone acetonideAnnexin A2target
DB00591Fluocinolone acetonideAnnexin A3target
DB00591Fluocinolone acetonideAnnexin A4target
DB00591Fluocinolone acetonideAnnexin A5target
DB01047FluocinonideCorticosteroid-binding globulincarrier
DB01047FluocinonideGlucocorticoid receptortarget
DB01047FluocinonideSmoothened homologtarget
DB01047FluocinonideCytochrome P450 3A4enzyme
DB01047FluocinonideCytochrome P450 3A5enzyme
DB08971FluocortoloneCytochrome P450 3A4enzyme
DB08971FluocortoloneCytochrome P450 3A5enzyme
DB00324FluorometholoneCorticosteroid-binding globulincarrier
DB00324FluorometholoneCytochrome P450 3A4enzyme
DB00324FluorometholoneGlucocorticoid receptortarget
DB00324FluorometholoneCytochrome P450 3A5enzyme
DB08970FluprednideneCytochrome P450 3A4enzyme
DB08970FluprednideneCytochrome P450 3A5enzyme
DB00846FlurandrenolideCorticosteroid-binding globulincarrier
DB00846FlurandrenolideGlucocorticoid receptortarget
DB00846FlurandrenolideCytochrome P450 3A4enzyme
DB13867FluticasoneCytochrome P450 3A4enzyme
DB13867FluticasoneCytochrome P450 2C8enzyme
DB13867FluticasoneP-glycoprotein 1carrier
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1carrier
DB13867FluticasoneP-glycoprotein 1transporter
DB13867FluticasoneSolute carrier organic anion transporter family member 1B1transporter
DB13867FluticasoneGlucocorticoid receptortarget
DB13867FluticasoneCorticosteroid-binding globulincarrier
DB13867FluticasoneCytochrome P450 3A5enzyme
DB13867FluticasoneCytochrome P450 3A7enzyme
DB13867FluticasoneProgesterone receptortarget
DB13867FluticasoneCytosolic phospholipase A2target
DB13867FluticasoneMineralocorticoid receptortarget
DB08906Fluticasone furoateCytochrome P450 3A4enzyme
DB08906Fluticasone furoateGlucocorticoid receptortarget
DB08906Fluticasone furoateP-glycoprotein 1transporter
DB08906Fluticasone furoateCytochrome P450 2C8enzyme
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
DB08906Fluticasone furoateCorticosteroid-binding globulincarrier
DB08906Fluticasone furoateP-glycoprotein 1carrier
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1carrier
DB08906Fluticasone furoateCytochrome P450 3A5enzyme
DB08906Fluticasone furoateCytochrome P450 3A7enzyme
DB08906Fluticasone furoateProgesterone receptortarget
DB08906Fluticasone furoateMineralocorticoid receptortarget
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateP-glycoprotein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB06786HalcinonideSmoothened homologtarget
DB06786HalcinonideCytochrome P450 3A4enzyme
DB13728HalometasoneCytochrome P450 3A4enzyme
DB13728HalometasoneCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateAnnexin A1target
DB14538Hydrocortisone aceponateGlucocorticoid receptortarget
DB14538Hydrocortisone aceponateSex hormone-binding globulincarrier
DB14538Hydrocortisone aceponateCytochrome P450 3A4enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A7enzyme
DB14538Hydrocortisone aceponateP-glycoprotein 1transporter
DB14538Hydrocortisone aceponateSolute carrier organic anion transporter family member 1A2transporter
DB14538Hydrocortisone aceponateATP-binding cassette sub-family G member 2transporter
DB14538Hydrocortisone aceponateCytochrome P450 2C8enzyme
DB14538Hydrocortisone aceponateCorticosteroid-binding globulincarrier
DB14538Hydrocortisone aceponateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14538Hydrocortisone aceponate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14538Hydrocortisone aceponateSolute carrier family 22 member 8transporter
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB14543Hydrocortisone probutateAnnexin A1target
DB14543Hydrocortisone probutateGlucocorticoid receptortarget
DB14543Hydrocortisone probutateSex hormone-binding globulincarrier
DB14543Hydrocortisone probutateCytochrome P450 3A4enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A5enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A7enzyme
DB14543Hydrocortisone probutateP-glycoprotein 1transporter
DB14543Hydrocortisone probutateSolute carrier organic anion transporter family member 1A2transporter
DB14543Hydrocortisone probutateATP-binding cassette sub-family G member 2transporter
DB14543Hydrocortisone probutateCytochrome P450 11B1, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 11B2, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 2C8enzyme
DB14543Hydrocortisone probutateCorticosteroid-binding globulincarrier
DB14543Hydrocortisone probutateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14543Hydrocortisone probutate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14543Hydrocortisone probutateSolute carrier family 22 member 8transporter
DB14540Hydrocortisone butyrateAnnexin A1target
DB14540Hydrocortisone butyrateGlucocorticoid receptortarget
DB14540Hydrocortisone butyrateSex hormone-binding globulincarrier
DB14540Hydrocortisone butyrateCytochrome P450 3A4enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A5enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A7enzyme
DB14540Hydrocortisone butyrateP-glycoprotein 1transporter
DB14540Hydrocortisone butyrateSolute carrier organic anion transporter family member 1A2transporter
DB14540Hydrocortisone butyrateATP-binding cassette sub-family G member 2transporter
DB14540Hydrocortisone butyrateCytochrome P450 11B1, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 11B2, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 2C8enzyme
DB14540Hydrocortisone butyrateCorticosteroid-binding globulincarrier
DB14540Hydrocortisone butyrateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14540Hydrocortisone butyrate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14540Hydrocortisone butyrateSolute carrier family 22 member 8transporter
DB14545Hydrocortisone succinateCytochrome P450 3A4enzyme
DB14545Hydrocortisone succinateCytochrome P450 2C8enzyme
DB14545Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
DB14545Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateAnnexin A1target
DB14544Hydrocortisone valerateGlucocorticoid receptortarget
DB14544Hydrocortisone valerateSex hormone-binding globulincarrier
DB14544Hydrocortisone valerateCytochrome P450 3A4enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A5enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A7enzyme
DB14544Hydrocortisone valerateP-glycoprotein 1transporter
DB14544Hydrocortisone valerateSolute carrier organic anion transporter family member 1A2transporter
DB14544Hydrocortisone valerateATP-binding cassette sub-family G member 2transporter
DB14544Hydrocortisone valerateCytochrome P450 11B1, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 2C8enzyme
DB14544Hydrocortisone valerateCorticosteroid-binding globulincarrier
DB14544Hydrocortisone valerateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14544Hydrocortisone valerate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14544Hydrocortisone valerateSolute carrier family 22 member 8transporter
DB14596Loteprednol etabonateGlucocorticoid receptortarget
DB14596Loteprednol etabonateCytochrome P450 3A4enzyme
DB14596Loteprednol etabonateSerum paraoxonase/arylesterase 1enzyme
DB00253MedrysoneCorticosteroid-binding globulincarrier
DB00253MedrysoneGlucocorticoid receptortarget
DB00253MedrysoneCytochrome P450 3A4enzyme
DB00253MedrysoneCytochrome P450 3A5enzyme
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB14512Mometasone furoateGlucocorticoid receptortarget
DB14512Mometasone furoateCytochrome P450 2C8enzyme
DB14512Mometasone furoateProgesterone receptortarget
DB14512Mometasone furoateCytochrome P450 3A4enzyme
DB14512Mometasone furoateCytochrome P450 3A5enzyme
DB01130PrednicarbateGlucocorticoid receptortarget
DB01130PrednicarbateCytochrome P450 3A4enzyme
DB00896RimexoloneCorticosteroid-binding globulincarrier
DB00896RimexoloneGlucocorticoid receptortarget
DB00896RimexoloneCytochrome P450 3A4enzyme
DB00896RimexoloneCytochrome P450 3A5enzyme
DB09091TixocortolGlucocorticoid receptortarget
DB09091TixocortolHistone deacetylase 2target
DB00596UlobetasolCorticosteroid-binding globulincarrier
DB00596UlobetasolGlucocorticoid receptortarget
DB11988OcrelizumabB-lymphocyte antigen CD20target
DB00072TrastuzumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00072TrastuzumabComplement C1r subcomponenttarget
DB00072TrastuzumabComplement C1q subcomponent subunit Atarget
DB00072TrastuzumabComplement C1q subcomponent subunit Btarget
DB00072TrastuzumabComplement C1q subcomponent subunit Ctarget
DB00072TrastuzumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00072TrastuzumabComplement C1s subcomponenttarget
DB00072TrastuzumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00072TrastuzumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00072TrastuzumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00072TrastuzumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00072TrastuzumabReceptor tyrosine-protein kinase erbB-2target
DB00072TrastuzumabEpidermal growth factor receptortarget
DB06643DenosumabTumor necrosis factor ligand superfamily member 11target
DB00859PenicillamineSolute carrier organic anion transporter family member 1B1transporter
DB00859PenicillamineCoppertarget
DB00328IndomethacinProstaglandin G/H synthase 1target
DB00328IndomethacinProstaglandin G/H synthase 2target
DB00328IndomethacinCytochrome P450 2C19enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndomethacinPhospholipase A2, membrane associatedtarget
DB00328IndomethacinProstaglandin reductase 2target
DB00328IndomethacinLactoylglutathione lyasetarget
DB00328IndomethacinProstaglandin D2 receptor 2target
DB00328IndomethacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndomethacinSerum albumincarrier
DB00328IndomethacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndomethacinMultidrug resistance-associated protein 4transporter
DB00328IndomethacinMultidrug resistance-associated protein 6transporter
DB00328IndomethacinP-glycoprotein 1transporter
DB00328IndomethacinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndomethacinSolute carrier family 22 member 6transporter
DB00328IndomethacinSolute carrier family 22 member 8transporter
DB00328IndomethacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndomethacinATP-binding cassette sub-family C member 11transporter
DB00328IndomethacinSolute carrier family 22 member 11transporter
DB00328IndomethacinSodium/bile acid cotransportertransporter
DB00328IndomethacinSolute carrier family 22 member 7transporter
DB00328IndomethacinCytochrome P450 2C9enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndomethacinLiver carboxylesterase 1enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndomethacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndomethacinAldo-keto reductase family 1 member C3target
DB00328IndomethacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndomethacinBile salt export pumptransporter
DB03523BrequinarDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB00033Interferon gamma-1bInterferon gamma receptor 1target
DB00033Interferon gamma-1bInterferon gamma receptor 2target
DB00033Interferon gamma-1bCytochrome P450 1A2enzyme
DB05472omega interferonInterferon alpha/beta receptor 1target
DB05472omega interferonInterferon alpha/beta receptor 2target
DB00011Interferon alfa-n1Interferon alpha/beta receptor 2target
DB00011Interferon alfa-n1Interferon alpha/beta receptor 1target
DB00011Interferon alfa-n1Cytochrome P450 1A2enzyme
DB09122Peginterferon beta-1aCytochrome P450 1A2enzyme
DB12814Cepeginterferon alfa-2BCytochrome P450 1A2enzyme
DB00068Interferon beta-1bInterferon alpha/beta receptor 1target
DB00068Interferon beta-1bInterferon alpha/beta receptor 2target
DB00068Interferon beta-1bCytochrome P450 1A2enzyme
DB00034Interferon alfa-2a, RecombinantInterferon alpha/beta receptor 1target
DB00034Interferon alfa-2a, RecombinantInterferon alpha/beta receptor 2target
DB00034Interferon alfa-2a, RecombinantCytochrome P450 1A2enzyme
DB05258Interferon alfaInterferon alpha/beta receptor 1target
DB05258Interferon alfaCytochrome P450 1A2enzyme
DB00105Interferon alfa-2bInterferon alpha/beta receptor 2target
DB00105Interferon alfa-2bInterferon alpha/beta receptor 1target
DB00105Interferon alfa-2bCytochrome P450 1A2enzyme
DB11569IxekizumabInterleukin-17Atarget
DB11817BaricitinibSolute carrier family 22 member 8transporter
DB11817BaricitinibATP-binding cassette sub-family G member 2transporter
DB11817BaricitinibMultidrug and toxin extrusion protein 2transporter
DB11817BaricitinibCytochrome P450 3A4enzyme
DB11817BaricitinibTyrosine-protein kinase JAK1target
DB11817BaricitinibTyrosine-protein kinase JAK2target
DB11817BaricitinibSolute carrier family 22 member 6transporter
DB11817BaricitinibSolute carrier family 22 member 2transporter
DB11817BaricitinibSolute carrier organic anion transporter family member 1B3transporter
DB11817BaricitinibProtein-tyrosine kinase 2-betatarget
DB11817BaricitinibTyrosine-protein kinase JAK3target
DB11834GuselkumabInterleukin-23 subunit alphatarget
DB14724EmapalumabInterferon gammatarget
DB12371SiponimodSphingosine 1-phosphate receptor 5target
DB12371SiponimodSphingosine 1-phosphate receptor 1target
DB12371SiponimodCytochrome P450 3A4enzyme
DB12371SiponimodCytochrome P450 2C9enzyme
DB14762RisankizumabInterleukin-23target
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateP-glycoprotein 1transporter
DB00394Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
DB11580RavulizumabComplement C5target
DB01394ColchicineTubulin beta chaintarget
DB01394ColchicineCytochrome P450 3A4enzyme
DB01394ColchicineP-glycoprotein 1transporter
DB01394ColchicineCytochrome P450 2B6enzyme
DB01394ColchicineCytochrome P450 2C8enzyme
DB01394ColchicineCytochrome P450 2E1enzyme
DB01394ColchicineSerum albumincarrier