Etidocaine

Identification

Name
Etidocaine
Accession Number
DB08987
Type
Small Molecule
Groups
Approved
Description

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

Structure
Thumb
Synonyms
Not Available
Product Ingredients
IngredientUNIICASInChI Key
Etidocaine hydrochlorideG6N3B3U8E636637-19-1LMWQQUMMGGIGJQ-UHFFFAOYSA-N
International/Other Brands
Duranest (AstraZeneca)
Categories
UNII
I6CQM0F31V
CAS number
36637-18-0
Weight
Average: 276.417
Monoisotopic: 276.220163528
Chemical Formula
C17H28N2O
InChI Key
VTUSIVBDOCDNHS-UHFFFAOYSA-N
InChI
InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)
IUPAC Name
N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanimidic acid
SMILES
CCCN(CC)C(CC)C(O)=NC1=C(C)C=CC=C1C

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Etidocaine.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Etidocaine.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Etidocaine.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Etidocaine.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Etidocaine.Approved, Investigational
AlaproclateThe risk or severity of adverse effects can be increased when Etidocaine is combined with Alaproclate.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Alfaxalone.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Etidocaine.Approved, Illicit
AllopregnanoloneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Allopregnanolone.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Etidocaine.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Alphaprodine.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Etidocaine.Approved, Illicit, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Etidocaine.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Amitriptyline is combined with Etidocaine.Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Etidocaine.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Amoxapine is combined with Etidocaine.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Etidocaine.Experimental
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Etidocaine.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Articaine.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Etidocaine.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Azaperone.Investigational, Vet Approved
AzelastineEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Etidocaine.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Etidocaine.Illicit
BenperidolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Benperidol.Approved, Investigational
BrexpiprazoleThe risk or severity of adverse effects can be increased when Brexpiprazole is combined with Etidocaine.Approved, Investigational
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Etidocaine.Approved, Illicit, Investigational
BromisovalThe risk or severity of adverse effects can be increased when Etidocaine is combined with Bromisoval.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Bromperidol.Approved, Investigational
BrotizolamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Brotizolam.Approved, Investigational, Withdrawn
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Etidocaine.Approved, Investigational
BuprenorphineEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Etidocaine.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Etidocaine.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Butacaine.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Etidocaine.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Etidocaine is combined with Butamben.Approved, Withdrawn
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Etidocaine.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Etidocaine.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Etidocaine.Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Etidocaine.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Etidocaine.Illicit, Investigational, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Etidocaine.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Etidocaine.Approved, Illicit, Investigational, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Etidocaine.Approved, Illicit, Investigational
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Etidocaine.Approved, Investigational, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Etidocaine.Approved
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Etidocaine.Approved, Investigational, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Etidocaine.Approved, Investigational, Withdrawn
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Etidocaine.Approved
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Etidocaine.Approved, Vet Approved
CitalopramThe risk or severity of adverse effects can be increased when Etidocaine is combined with Citalopram.Approved
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Etidocaine.Approved
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Etidocaine.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Etidocaine.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Etidocaine.Approved, Investigational, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Etidocaine.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Etidocaine.Approved
ClopenthixolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Clopenthixol.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Etidocaine.Approved, Illicit
ClothiapineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Clothiapine.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Etidocaine.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Etidocaine.Approved, Illicit
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Etidocaine.Approved
CyclopropaneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Cyclopropane.Experimental
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Etidocaine.Approved
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Etidocaine.Approved, Investigational
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Etidocaine.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Dapoxetine.Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Etidocaine.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Etidocaine.Approved
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Etidocaine.Approved, Investigational
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Etidocaine.Approved, Investigational
DetomidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Detomidine.Vet Approved
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Etidocaine.Approved, Vet Approved
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Etidocaine.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Etidocaine.Approved, Illicit, Investigational, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Etidocaine.Approved, Investigational
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Etidocaine.Approved, Illicit, Investigational, Vet Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Etidocaine is combined with Diethyl ether.Experimental
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Etidocaine.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Etidocaine.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Etidocaine.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Etidocaine.Experimental, Illicit
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Etidocaine.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Dixyrazine.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Etidocaine is combined with Doramectin.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Doxepin is combined with Etidocaine.Approved, Investigational
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Etidocaine.Experimental
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Etidocaine.Experimental, Illicit
DuloxetineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Etidocaine.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Etidocaine.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Ecopipam.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Efavirenz is combined with Etidocaine.Approved, Investigational
EltanoloneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Eltanolone.Investigational
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Etidocaine.Approved, Investigational, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Etidocaine.Approved, Investigational
EscitalopramThe risk or severity of adverse effects can be increased when Etidocaine is combined with Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Etidocaine.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Etidocaine.Approved, Investigational
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Etidocaine.Approved, Illicit, Withdrawn
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Etidocaine.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Etidocaine.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Ethyl chloride.Approved, Experimental, Investigational
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Etidocaine.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Etidocaine.Approved, Illicit
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Etidocaine.Investigational, Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Etizolam.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Etoperidone.Withdrawn
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Etidocaine.Illicit, Vet Approved
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Etidocaine.Approved, Investigational
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Etidocaine.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Etidocaine.Approved, Illicit, Withdrawn
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Etidocaine.Approved, Investigational
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Etidocaine.Approved, Investigational
FluanisoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Fluanisone.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Etidocaine.Approved, Illicit
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Etidocaine.Approved, Illicit
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Etidocaine.Approved, Investigational, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Etidocaine.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Etidocaine.Approved, Illicit, Investigational
FosphenytoinThe risk or severity of adverse effects can be increased when Fosphenytoin is combined with Etidocaine.Approved, Investigational
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Etidocaine.Approved, Illicit, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Gabapentin Enacarbil is combined with Etidocaine.Approved, Investigational
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Etidocaine.Approved, Illicit, Investigational
GepironeThe risk or severity of adverse effects can be increased when Etidocaine is combined with Gepirone.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Etidocaine.Approved, Illicit
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Etidocaine.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Etidocaine.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Etidocaine.Approved, Vet Approved
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Etidocaine.Approved, Illicit, Investigational
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Etidocaine.Approved
HyaluronidaseThe risk or severity of adverse effects can be increased when Hyaluronidase is combined with Etidocaine.Approved, Investigational
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Etidocaine.Approved, Illicit
IloperidoneThe risk or severity of adverse effects can be increased when Iloperidone is combined with Etidocaine.Approved
ImipramineThe risk or severity of adverse effects can be increased when Imipramine is combined with Etidocaine.Approved
IndalpineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Indalpine.Investigational, Withdrawn
IndiplonThe risk or severity of adverse effects can be increased when Etidocaine is combined with Indiplon.Investigational
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Etidocaine.Approved, Vet Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Etidocaine.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Etidocaine.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Etidocaine.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Etidocaine.Approved, Investigational
LevocabastineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Levocabastine.Approved, Investigational
LevocetirizineThe risk or severity of adverse effects can be increased when Levocetirizine is combined with Etidocaine.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Etidocaine.Approved, Investigational
LevomilnacipranThe risk or severity of adverse effects can be increased when Etidocaine is combined with Levomilnacipran.Approved, Investigational
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Etidocaine.Approved
Lithium cationThe risk or severity of adverse effects can be increased when Lithium is combined with Etidocaine.Experimental
LofentanilThe risk or severity of adverse effects can be increased when Etidocaine is combined with Lofentanil.Illicit
LofexidineThe therapeutic efficacy of Etidocaine can be increased when used in combination with Lofexidine.Approved, Investigational
LoprazolamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Loprazolam.Experimental
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Etidocaine.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Lormetazepam.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Etidocaine.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Etidocaine.Approved, Investigational
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Etidocaine.Approved, Investigational
MebicarThe risk or severity of adverse effects can be increased when Etidocaine is combined with Mebicar.Experimental
MedazepamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Medazepam.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Medetomidine.Vet Approved
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Etidocaine.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Melperone.Approved, Investigational
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Etidocaine.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Etidocaine.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Meptazinol.Experimental
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Etidocaine.Approved, Investigational
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Etidocaine.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Etidocaine.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Etidocaine.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Etidocaine.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Etidocaine.Illicit, Withdrawn
MethocarbamolThe risk or severity of adverse effects can be increased when Methocarbamol is combined with Etidocaine.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Etidocaine.Approved
MethotrimeprazineEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved, Investigational
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Etidocaine.Approved, Investigational, Vet Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Etidocaine.Experimental
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Etidocaine.Approved
MetyrosineEtidocaine may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Etidocaine.Approved, Illicit
MilnacipranThe risk or severity of adverse effects can be increased when Etidocaine is combined with Milnacipran.Approved, Investigational
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved, Investigational
MirtazapineEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Etidocaine.Approved
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Etidocaine.Approved, Investigational
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Etidocaine.Approved
NefazodoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Nefazodone.Approved, Withdrawn
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Etidocaine.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Etidocaine.Approved, Vet Approved
NordazepamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Nordazepam.Approved
NorfluraneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Norflurane.Approved, Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Normethadone.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Nortriptyline is combined with Etidocaine.Approved
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Etidocaine.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Etidocaine.Approved
OpiumThe risk or severity of adverse effects can be increased when Etidocaine is combined with Opium.Approved, Illicit
OrphenadrineEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Etidocaine.Investigational
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Etidocaine.Approved
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Etidocaine.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Etidocaine.Approved, Investigational
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Etidocaine.Approved
ParaldehydeEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved, Investigational
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Etidocaine.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Etidocaine.Approved, Investigational, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved
PerazineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Perazine.Approved, Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Etidocaine.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Etidocaine.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Etidocaine.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Phenazocine.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Etidocaine is combined with Phenibut.Experimental
PhenoperidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Phenoperidine.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Phenoxyethanol.Approved
PhenytoinThe risk or severity of adverse effects can be increased when Phenytoin is combined with Etidocaine.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Etidocaine.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Pipamperone.Approved, Investigational
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Etidocaine.Approved, Investigational
PiritramideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Piritramide.Approved, Investigational
PizotifenThe risk or severity of adverse effects can be increased when Pizotifen is combined with Etidocaine.Approved
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Etidocaine.Approved
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Etidocaine.Approved, Illicit
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Etidocaine.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Primidone is combined with Etidocaine.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Etidocaine.Approved, Investigational, Vet Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Etidocaine.Approved, Vet Approved
PropanididThe risk or severity of adverse effects can be increased when Etidocaine is combined with Propanidid.Experimental
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Etidocaine.Approved, Vet Approved
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Etidocaine.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Propoxycaine.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Etidocaine.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Etidocaine is combined with Proxibarbal.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Etidocaine.Investigational
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Etidocaine.Approved, Illicit
QuinisocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Quinisocaine.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Raclopride.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Ramelteon is combined with Etidocaine.Approved, Investigational
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Etidocaine.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Etidocaine.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Etidocaine.Approved, Investigational
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Etidocaine.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Etidocaine is combined with Ritanserin.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Romifidine.Vet Approved
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Etidocaine.Approved
RotigotineEtidocaine may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Etidocaine.Approved
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Etidocaine.Approved, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Sepranolone.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Etidocaine.Approved, Investigational, Withdrawn
SertralineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Etidocaine.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved
StiripentolThe risk or severity of adverse effects can be increased when Stiripentol is combined with Etidocaine.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Etidocaine.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Etidocaine.Approved, Investigational
SultoprideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Sultopride.Experimental
SuvorexantEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved, Investigational
TandospironeThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Tasimelteon is combined with Etidocaine.Approved, Investigational
Technetium Tc-99m tilmanoceptEtidocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.Approved, Investigational
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Etidocaine.Approved, Investigational
TetrabenazineThe risk or severity of adverse effects can be increased when Tetrabenazine is combined with Etidocaine.Approved, Investigational
TetracaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tetracaine.Approved, Vet Approved
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Etidocaine.Investigational
ThalidomideEtidocaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Etidocaine.Approved, Vet Approved
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Etidocaine.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Etidocaine.Approved, Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Etidocaine.Approved
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Etidocaine.Approved, Investigational
TiaprideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tiapride.Approved, Investigational
TiletamineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tiletamine.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tilidine.Experimental
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Etidocaine.Approved, Investigational
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Etidocaine.Approved, Withdrawn
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Etidocaine.Approved, Investigational
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Etidocaine.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Etidocaine.Approved, Investigational
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Etidocaine is combined with Tricaine methanesulfonate.Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Etidocaine is combined with Trichloroethylene.Approved
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Etidocaine.Approved, Investigational
TrifluperidolThe risk or severity of adverse effects can be increased when Etidocaine is combined with Trifluperidol.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Etidocaine.Approved, Vet Approved
TrimipramineThe risk or severity of adverse effects can be increased when Trimipramine is combined with Etidocaine.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Etidocaine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Etidocaine is combined with Veralipride.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Etidocaine.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Etidocaine is combined with Vinyl ether.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Vortioxetine.Approved, Investigational
XenonThe risk or severity of adverse effects can be increased when Etidocaine is combined with Xenon.Experimental
XylazineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Xylazine.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Etidocaine.Approved, Illicit, Investigational
ZimelidineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Etidocaine.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Etidocaine is combined with Zolazepam.Vet Approved
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Etidocaine.Approved
ZotepineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Zotepine.Approved, Investigational, Withdrawn
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Etidocaine.Approved, Investigational
Food Interactions
Not Available

References

Synthesis Reference

U.S. Patent 3,812,147.

General References
Not Available
External Links
KEGG Drug
D04095
KEGG Compound
C07530
PubChem Compound
37497
PubChem Substance
310264948
ChemSpider
34400
ChEBI
4904
ChEMBL
CHEMBL492
Wikipedia
Etidocaine
ATC Codes
N01BB07 — EtidocaineN01BB57 — Etidocaine, combinations

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)203-203.5U.S. Patent 3,812,147.
Predicted Properties
PropertyValueSource
Water Solubility0.0457 mg/mLALOGPS
logP3.66ALOGPS
logP2.78ChemAxon
logS-3.8ALOGPS
pKa (Strongest Acidic)4.97ChemAxon
pKa (Strongest Basic)9.4ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area35.83 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity88.23 m3·mol-1ChemAxon
Polarizability33.38 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Amino acids, peptides, and analogues
Direct Parent
Alpha amino acid amides
Alternative Parents
Anilides / m-Xylenes / N-arylamides / Fatty amides / Trialkylamines / Secondary carboxylic acid amides / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
Substituents
Alpha-amino acid amide / Anilide / N-arylamide / M-xylene / Xylene / Monocyclic benzene moiety / Fatty amide / Benzenoid / Fatty acyl / Carboxamide group
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
amino acid amide (CHEBI:4904)

Drug created on June 10, 2014 15:18 / Updated on August 02, 2018 07:53