Aniline Compounds

Compounds that include the aminobenzene structure.
DrugDrug NameDrug Indication
DB00259SulfanilamideFor the treatment of vulvovaginitis caused by Candida albicans.
DB00263SulfisoxazoleFor the treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.
DB00265CrotamitonFor eradication of scabies (Sarcoptes scabiei) and for symptomatic treatment of pruritic skin.
DB00359SulfadiazineFor the treatment of rheumatic fever and meningococcal meningitis
DB00406Gentian violet cationFor the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
DB00576SulfamethizoleFor the treatment of urinary tract infection
DB00634SulfacetamideFor the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis.
DB00664SulfametopyrazineFor the treatment of urinary tract infection and chronic bronchitis.
DB00695FurosemideFurosemide is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. It is also indicated for the treatment of hypertension alone or in combination with other antihypertensive agents in adults who were not shown to be inadequately controlled with thiazides.[L7958]
DB00784Mefenamic acidFor the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
DB00891SulfapyridineFor the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum
DB00939Meclofenamic acidFor the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
DB01015SulfamethoxazoleFor the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
DB01298SulfacytineUsed orally in the treatment of acute urinary tract infections.
DB01299SulfadoxineSulfadoxine is used in combination with pyrimethamine for the treatment or prevention of malaria. It can also be used to treat various infections in livestock as well. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in those patients in whom chloroquine resistance is suspected.
DB01581SulfamerazineA sulfanilamide that is used as an antibacterial agent. It can be used to treat bronchitis, prostatitis and urinary tract infections.
DB01582SulfamethazineFor the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
DB017262-AminophenolNot Available
DB02266Flufenamic acidNot Available
DB031804,5-Dimethyl-1,2-PhenylenediamineNot Available
DB03895Malachite GreenNot Available
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB04953EzogabineAdjuvant treatment of partial-onset seizures.
DB05245Silver sulfadiazineIndicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
DB06147SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
DB06150SulfadimethoxineFor use in the treatment of infections.
DB06309RefametinibInvestigated for use/treatment in cancer/tumors (unspecified).
DB06729SulfaphenazoleFor the treatment bacterial infections.
DB06742AmbroxolAmbroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.
DB06821SulfameterNot Available
DB08798SulfamoxoleFor the treatment of bacterial infection.
DB08820IvacaftorWhen used as monotherapy as the product Kalydeco, ivacaftor is indicated for the management of CF in patients age 2 years and older who have a mutation in the CFTR gene that is responsive to ivacaftor potentiation. Ivacaftor received expanded approval in May 2017 for the following 33 CFTR mutations: E56K, P67L, R74W, D110E, D110H, R117C, R117H, G178R, E193K, L206W, R347H, R352Q, A455E, S549N, S549R, G551D, G551S, D579G, S945L, S977F, F1052V, K1060T, A1067T, G1069R, R1070Q, R1070W, F1074L, D1152H, G1244E, S1251N, S1255P, D1270N, and G1349D.[L768,L6838] When used in combination with the drug [DB09280] as the product Orkambi, ivacaftor is indicated for the management of CF patients age 6 years and older who are shown to be homozygous for the F508del mutation in the CFTR gene. When used in combination with [Tezacaftor] in the product Symdeko, it is used to manage CF in patients 12 years and older who have at least one mutation in the CFTR gene or patients aged 12 or older who are shown to be homozygous for the F508del mutation.[L6814]
DB08880TeriflunomideUsed in the treatment of relapsing forms of multiple sclerosis (MS).
DB08961AzosemideNot Available
DB08984EtofenamateNot Available
DB09019BromhexineNot Available
DB09136Isosulfan blueIsosulfan Blue is a synthetic visual lymphatic imaging agent. Isosulfan blue upon subcutaneous administration, delineates the lymphatic vessels draining the region of injection. It is an adjunct to lymphography in: primary and secondary lymphedema of the extremities; chyluria, chylous ascites or chylothorax; lymph node involvement by primary or secondary neoplasm; lymph node response to therapeutic modalities.
DB09285Morniflumate Morniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for the treatment of pain associated with ear, nose, throat (ENT) and gastrointestinal inflammatory conditions in children. Morniflumate is a well established NSAID that has been in use for over three decades in Italy (particularly for the treatment of upper respiratory tract infections in children), France, Belgium, Austria, Switzerland, Spain and Portugal; it has a generally favorable tolerability profile.
DB11269Diethylamino hydroxybenzoyl hexyl benzoateIndicated for use as a sunscreen agent.
DB11373AmitrazNot Available
DB11389ClorsulonNot Available
DB11455RobenacoxibNot Available
DB11461SulfachlorpyridazineNot Available
DB11462SulfaethoxypyridazineNot Available
DB11463SulfanitranNot Available
DB11464SulfaquinoxalineNot Available
DB12254ABT-751Not Available
DB12921ChlorsulfaquinoxalineNot Available
DB13141Ambroxol acefyllinateNot Available
DB13239NeltenexineNot Available
DB13248PhthalylsulfathiazoleNot Available
DB13278BucetinNot Available
DB13283SulfaisodimidineNot Available
DB13547SulfatolamideNot Available
DB135494-dimethylaminophenolNot Available
DB13580SuccinylsulfathiazoleNot Available
DB13699SulfathioureaNot Available
DB13726SulfaguanidineNot Available
DB13773SulfamethoxypyridazineNot Available
DB14033Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the absence of obstructive uropathy or foreign bodies [L2804] Meningococcal meningitis where the organism has been demonstrated to be susceptible. Haemophilus influenzae meningitis as adjunctive therapy with parenteral streptomycin [L2804] Meningococcal meningitis prophylaxis [L2804]. Acute otitis media due to Haemophilus influenzae when used concomitantly with adequate doses of penicillin or erythromycin (see appropriate labeling for prescribing information) [L2804]. Trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis as adjunctive therapy with pyrimethamine. Malaria due to chloroquine-resistant strains of Plasmodium falciparum, when used as adjunctive therapy [L2804]. Currently, the increasing frequency of resistant organisms is a limitation of the usefulness of antibacterial agents including the sulfonamides, especially in the treatment of chronic and recurrent urinary tract infections [L2804].
DB14141p-PhenylenediamineNot Available
DB14144p-AminophenolNot Available
DB14192N,N'-diphenyl-1,4-phenylenediamineNot Available
DB141954-(Isopropylamino)diphenylamine4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
DB14196N-Cyclohexyl-N'-phenyl-1,4-phenylenediamineN-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
DB13967Patent BluePatent blue is used for marking lymphatic vessels and arterial territories as well as for sentinel lymph node prior to biopsy in patients with operable breast cancer and clinically negative lymph nodes in combination with a radiotracer.[A32575] Patent blue is also used in the textile, paper, agriculture and cosmetic industry.[A32574]
DB07101PD-0325901Not Available
DB00243RanolazineRanolazine is approved as a second-line agent in the management of chronic stable angina pectoris that is refractory to conventional anti-ischemic therapy.[A174913] Ranolazine has also been used off-label for the treatment of some arrhythmias such as ventricular tachycardia, however, this use does not have a lot of supporting evidence.[A174940] The use of ranolazine has been researched in the treatment of acute coronary syndrome, microvascular coronary dysfunction, arrhythmia, and glycemic control.[A174898]
DB00281LidocaineLidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930].
DB00296RopivacaineUsed in obstetric anesthesia and regional anesthesia for surgery.
DB00297BupivacaineFor the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
DB00316AcetaminophenIn general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever [F4124]. It is available over the counter in various forms, the most common being oral forms. Acetaminophen _injection_ is indicated for [FDA label]: • Management of mild to moderate pain • Management of moderate to severe pain with adjunctive opioid analgesics • Reduction of fever Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics [F4124]. Specific dosing guidelines should be followed when administering acetaminophen to children [L5780].
DB00499FlutamideFor the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate
DB00750PrilocaineUsed as a local anaesthetic and is often used in dentistry.
DB01002LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
DB01056TocainideFor the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.
DB01128BicalutamideFor treatment (together with surgery or LHRH analogue) of advanced prostatic cancer.
DB01228EncainideEncainide is a class Ic antiarrhythmic agent which was used for management of irregular heartbeats, such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation.
DB01297PractololUsed in the emergency treatment of cardiac arrhythmias.
DB02546VorinostatFor the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following two systemic therapies.
DB03783PhenacetinUsed principally as an analgesic.
DB04657CarboxinNot Available
DB05035EprotiromeInvestigated for use/treatment in hyperlipidemia, metabolic disease, and obesity.
DB05409NCX 701Investigated for use/treatment in pain (acute or chronic).
DB05871UC-781Investigated for use/treatment in HIV infection.
DB06803NiclosamideFor the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used as a molluscicide in the control of schistosomiasis.
DB07419S-23Not Available
DB08828VismodegibVismodegib is used for treating locally advanced or metastatic basal cell carcinoma in patients whose carcinoma has recurred after surgery, and in patients who are not candidates for surgery or radiation.
DB08875CabozantinibFor the treatment of metastatic medullary thyroid cancer and for the treatment of patients with advanced renal cell carcinoma (RCC) who have received prior anti-angiogenic therapy.
DB08893MirabegronMirabegron is a beta-3 adrenergic agonist indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.
DB08987EtidocaineNot Available
DB09288PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.[L1511]
DB09296OmbitasvirWhen used in combination with [DB09297] and [DB00503] (as the fixed dose product Technivie), Ombitasvir is indicated in combination with [DB00811] for the treatment of patients with genotype 4 chronic hepatitis C virus (HCV) infection without cirrhosis [L866]. When used in combination with [DB09297], [DB00503], and [DB09183] (as the fixed dose product Viekira Pak), Ombitasvir is indicated for the treatment of HCV genotype 1b and ,when combined with [DB00811], for the treatment of HCV genotype 1a [FDA Label]
DB11155TriclocarbanTriclocarban (TCC), or 3,4,4'-trichlorocarbanilide, is an antibacterial agent used in bar and liquid soaps and body washes [L2685].
DB11521ImidocarbNot Available
DB12078EnobosarmNot Available
DB12307ForetinibNot Available
DB12712PilsicainideNot Available
DB13156Inosine pranobexInosine pranobex is also indicated for mucocutaneous infections due to herpes simplex virus (type 1 and type II) and for treatment of genital warts as adjunctive therapy to podophyllin or carbon dioxide laser.
DB13328ButanilicaineNot Available
DB13657BenorilateNot Available
DB14728MebenilNot Available
DB15036SitravatinibNot Available
DB15189BirabresibNot Available
DB15321TefinostatNot Available
DrugDrug NameTargetType
DB00259SulfanilamideDihydropteroate synthasetarget
DB00259SulfanilamideCytochrome P450 2C19enzyme
DB00259SulfanilamideCytochrome P450 2D6enzyme
DB00259SulfanilamideCytochrome P450 2E1enzyme
DB00259SulfanilamideCytochrome P450 3A4enzyme
DB00263SulfisoxazoleDihydropteroate synthasetarget
DB00263SulfisoxazoleCytochrome P450 2C9enzyme
DB00359SulfadiazineCytochrome P450 2C9enzyme
DB00359SulfadiazineDihydropteroate synthetasetarget
DB00359SulfadiazineCytochrome P450 2C8enzyme
DB00359SulfadiazineCytochrome P450 3A4enzyme
DB00406Gentian violet cationDNAtarget
DB00406Gentian violet cationSolute carrier family 22 member 1transporter
DB00576SulfamethizoleDihydropteroate synthasetarget
DB00576SulfamethizoleSerum albumincarrier
DB00576SulfamethizoleCytochrome P450 2C9enzyme
DB00634SulfacetamideDihydropteroate synthasetarget
DB00634SulfacetamideDihydropteroate synthase type-1target
DB00634SulfacetamideFolic acid synthesis protein FOL1target
DB00664SulfametopyrazineDihydropteroate synthetasetarget
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00891SulfapyridineDihydropteroate synthase type-1target
DB00891SulfapyridineCytochrome P450 2C9enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB01015SulfamethoxazoleBifunctional protein FolCtarget
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01015SulfamethoxazoleBile salt export pumptransporter
DB01298SulfacytineDihydropteroate synthasetarget
DB01299SulfadoxineDihydropteroate synthetasetarget
DB01299SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01581SulfamerazineDihydropteroate synthasetarget
DB01581SulfamerazineSerum albumincarrier
DB01582SulfamethazineDihydropteroate synthasetarget
DB01582SulfamethazineSerum albumincarrier
DB01582SulfamethazineArylamine N-acetyltransferaseenzyme
DB017262-AminophenolNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB02266Flufenamic acidAldo-keto reductase family 1 member C3target
DB02266Flufenamic acidTransthyretincarrier
DB02266Flufenamic acidProstaglandin G/H synthase 2target
DB02266Flufenamic acidProstaglandin G/H synthase 1target
DB02266Flufenamic acidSolute carrier family 22 member 6transporter
DB02266Flufenamic acidAndrogen receptortarget
DB02266Flufenamic acidPeroxisome proliferator-activated receptor alphatarget
DB02266Flufenamic acidPeroxisome proliferator-activated receptor gammatarget
DB031804,5-Dimethyl-1,2-PhenylenediamineNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB03895Malachite GreenHTH-type transcriptional regulator QacRtarget
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 2target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 3target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 4target
DB04953EzogabinePotassium voltage-gated channel subfamily KQT member 5target
DB04953EzogabineUDP-glucuronosyltransferase 1-1enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-3enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-4enzyme
DB04953EzogabineUDP-glucuronosyltransferase 1-9enzyme
DB04953EzogabineArylamine N-acetyltransferase 2enzyme
DB05245Silver sulfadiazineDNAtarget
DB06147SulfathiazoleDihydropteroate synthetasetarget
DB06147SulfathiazoleCytochrome P450 19A1enzyme
DB06150SulfadimethoxineCytochrome P450 2C9enzyme
DB06729SulfaphenazoleCytochrome P450 2C9enzyme
DB06729SulfaphenazoleCytochrome P450 2B6enzyme
DB06729SulfaphenazoleCytochrome P450 2C8enzyme
DB06729SulfaphenazoleCytochrome P450 2D6enzyme
DB06729SulfaphenazoleDihydropteroate synthasetarget
DB06742AmbroxolCytochrome P450 3A4enzyme
DB06821SulfameterDihydropteroate synthasetarget
DB08798SulfamoxoleDihydropteroate synthetasetarget
DB08798SulfamoxoleCytochrome P450 2C9enzyme
DB08820IvacaftorCystic fibrosis transmembrane conductance regulatortarget
DB08820IvacaftorCytochrome P450 3A4enzyme
DB08820IvacaftorSerum albumincarrier
DB08820IvacaftorAlpha-1-acid glycoprotein 1carrier
DB08820IvacaftorMultidrug resistance protein 1transporter
DB08820IvacaftorCytochrome P450 3A5enzyme
DB08880TeriflunomideATP-binding cassette sub-family G member 2transporter
DB08880TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB08880TeriflunomideCytochrome P450 2C8enzyme
DB08880TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
DB08880TeriflunomideCytochrome P450 1A2enzyme
DB08984EtofenamateThyroxine-binding globulincarrier
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1A9enzyme
DB11455RobenacoxibCyclooxygenase 2target
DB13141Ambroxol acefyllinateCYP3Aenzyme
DB14033Acetyl sulfisoxazoleDihydropteroate synthasetarget
DB14033Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
DB13967Patent BlueSerum albumintarget
DB07101PD-0325901Dual specificity mitogen-activated protein kinase kinase 1target
DB00243RanolazineCytochrome P450 3A4enzyme
DB00243RanolazineCytochrome P450 2D6enzyme
DB00243RanolazineBile salt export pumptransporter
DB00243RanolazineMultidrug resistance protein 1transporter
DB00243RanolazineSerum albumincarrier
DB00243RanolazineVoltage gated sodium channeltarget
DB00243RanolazineInward rectifier potassium channeltarget
DB00243RanolazineVoltage-dependent L-type calcium channeltarget
DB00243RanolazineAlpha-1 adrenergic receptorstarget
DB00243RanolazineBeta-1 adrenergic receptortarget
DB00243RanolazineFatty acidtarget
DB00243RanolazineAlpha-1-acid glycoprotein 1carrier
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineMultidrug resistance protein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00296RopivacaineSodium channel protein type 10 subunit alphatarget
DB00296RopivacaineCytochrome P450 1A2enzyme
DB00296RopivacaineCytochrome P450 2B6enzyme
DB00296RopivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenMultidrug resistance protein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin G/H synthase 3target
DB00316AcetaminophenFatty-acid amide hydrolase 1target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenGlutathione S-transferase Ptarget
DB00499FlutamideAndrogen receptortarget
DB00499FlutamideCytochrome P450 1A2enzyme
DB00499FlutamideCytochrome P450 3A4enzyme
DB00499FlutamideCytochrome P450 1A1enzyme
DB00499FlutamideCytochrome P450 1B1enzyme
DB00499FlutamideCytochrome P450 2C19enzyme
DB00499FlutamideCytochrome P450 3A5enzyme
DB00499FlutamideAryl hydrocarbon receptortarget
DB00499FlutamideNuclear receptor subfamily 1 group I member 2target
DB00750PrilocaineSodium channel protein type 5 subunit alphatarget
DB01002LevobupivacaineSodium channel protein type 10 subunit alphatarget
DB01002LevobupivacaineCytochrome P450 3A4enzyme
DB01002LevobupivacaineCytochrome P450 1A2enzyme
DB01056TocainideSodium channel protein type 5 subunit alphatarget
DB01056TocainideSerum albumincarrier
DB01056TocainideCytochrome P450 1A2enzyme
DB01128BicalutamideAndrogen receptortarget
DB01128BicalutamideCytochrome P450 3A4enzyme
DB01128BicalutamideCytochrome P450 2C19enzyme
DB01128BicalutamideCytochrome P450 2C9enzyme
DB01128BicalutamideCytochrome P450 2D6enzyme
DB01228EncainideSodium channel protein type 5 subunit alphatarget
DB01228EncainideCytochrome P450 2D6enzyme
DB01297PractololBeta-1 adrenergic receptortarget
DB01297PractololCytochrome P450 2D6enzyme
DB02546VorinostatHistone deacetylase 1target
DB02546VorinostatHistone deacetylase 2target
DB02546VorinostatHistone deacetylase 3target
DB02546VorinostatHistone deacetylase 6target
DB02546VorinostatHistone deacetylase 8target
DB02546VorinostatAcetoin utilization proteintarget
DB03783PhenacetinProstaglandin G/H synthase 1target
DB03783PhenacetinCytochrome P450 1A2enzyme
DB03783PhenacetinCytochrome P450 2D6enzyme
DB03783PhenacetinSolute carrier family 22 member 6transporter
DB03783PhenacetinCytochrome P450 1A1enzyme
DB03783PhenacetinCytochrome P450 2A13enzyme
DB03783PhenacetinCytochrome P450 2A6enzyme
DB03783PhenacetinCytochrome P450 2C19enzyme
DB03783PhenacetinCytochrome P450 2C9enzyme
DB03783PhenacetinCytochrome P450 2E1enzyme
DB03783PhenacetinCytochrome P450 3A4enzyme
DB04657CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
DB05035EprotiromeThyroid hormone receptor alphatarget
DB05035EprotiromeThyroid hormone receptor betatarget
DB05871UC-781Gag-Pol polyproteintarget
DB06803NiclosamideCytochrome P450 2C9enzyme
DB06803NiclosamideCytochrome P450 1A2enzyme
DB07419S-23Androgen receptortarget
DB08407PLATENSIMYCIN3-oxoacyl-[acyl-carrier-protein] synthase 2target
DB08828VismodegibSmoothened homologtarget
DB08828VismodegibCytochrome P450 2C9enzyme
DB08828VismodegibCytochrome P450 3A4enzyme
DB08828VismodegibMultidrug resistance protein 1transporter
DB08828VismodegibCytochrome P450 2C8enzyme
DB08828VismodegibCytochrome P450 2C19enzyme
DB08828VismodegibATP-binding cassette sub-family G member 2transporter
DB08828VismodegibSerum albumincarrier
DB08828VismodegibAlpha-1-acid glycoprotein 1carrier
DB08875CabozantinibCytochrome P450 3A4enzyme
DB08875CabozantinibCytochrome P450 2C9enzyme
DB08875CabozantinibHepatocyte growth factor receptortarget
DB08875CabozantinibVascular endothelial growth factor receptor 2target
DB08875CabozantinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB08875CabozantinibCytochrome P450 2C8enzyme
DB08893MirabegronCytochrome P450 3A4enzyme
DB08893MirabegronCytochrome P450 2D6enzyme
DB08893MirabegronMultidrug resistance protein 1transporter
DB08893MirabegronSolute carrier organic anion transporter family member 1A2transporter
DB08893MirabegronSerum albumincarrier
DB08893MirabegronAlpha-1-acid glycoprotein 1carrier
DB08893MirabegronBeta-3 adrenergic receptortarget
DB09288PropacetamolProstaglandin G/H synthase 1target
DB09288PropacetamolProstaglandin G/H synthase 2target
DB09288PropacetamolTransient receptor potential cation channel subfamily V member 1target
DB09288PropacetamolCannabinoid receptor 1target
DB09288PropacetamolCytochrome P450 3A4enzyme
DB09288PropacetamolCytochrome P450 2E1enzyme
DB09288PropacetamolCytochrome P450 1A2enzyme
DB09288PropacetamolCytochrome P450 2D6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-1enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-9enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 2B15enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-10enzyme
DB09288PropacetamolSulfotransferase 1A1enzyme
DB09288PropacetamolSulfotransferase 1A3/1A4enzyme
DB09288PropacetamolEstrogen sulfotransferaseenzyme
DB09288PropacetamolBile salt sulfotransferaseenzyme
DB09288PropacetamolArylamine N-acetyltransferase 2enzyme
DB09288PropacetamolCytochrome P450 2C9enzyme
DB09296OmbitasvirNonstructural protein 5Atarget
DB09296OmbitasvirCytochrome P450 2C8enzyme
DB09296OmbitasvirMultidrug resistance protein 1transporter
DB09296OmbitasvirUDP-glucuronosyltransferase 1A1transporter
DB09296OmbitasvirATP-binding cassette sub-family G member 2transporter
DB11155TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
DB11155TriclocarbanCytochrome P450 1A1enzyme
DB11155TriclocarbanCytochrome P450 1B1enzyme
DB12307ForetinibHepatocyte growth factortarget
DB12307ForetinibVascular endothelial growth factor receptor 2target
DB12712PilsicainideBile salt export pumptransporter