Valerian

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Valerian
Accession Number
DB13196
Type
Biotech
Groups
Approved, Experimental, Investigational
Biologic Classification
Allergenics
Allergen Extract
Description

Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain. Valproic acid is a derivative of valeric acid, which is obtained from the plant root. Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

Synonyms
  • Valerianae radix
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Artryl Cap 200 mgCapsuleOralLes Laboratoires Vachon Inc.1994-12-312007-07-12Canada
Effidose Valeriane Liq 1916mg/10ml AmpLiquidOralLaboratoires Charton Laboratories1995-12-311999-01-16Canada
Ethical Herbals Sleep AidTabletOralAshbury Research CorporationNot applicableNot applicableCanada
Facilite Le Sommeil - Cap 270mgCapsuleOralLaboratoire Lalco Inc.1997-01-202002-09-05Canada
Hermes No6 TeaLiquidOralHermes Arzneimittel Gmbh1958-12-311999-07-08Canada
Kalm CapsCapsuleOralRheingold Food International Ltd.1985-12-312001-07-06Canada
Nervatex Tab 500mgTabletOralCarmaran LtÉe1980-12-311996-09-09Canada
Nervatex Tablets 500mgTabletOralPharmetics (2011) Inc.1995-12-312000-08-21Canada
PhytocalmCapsuleOralSantÉ Naturelle (Ag) LtÉe1998-12-132004-08-05Canada
Salus Valerian TctTinctureOralSalus Haus1979-12-312003-07-24Canada
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Bio-strath No. 8 GouttesValerian (0.225 ml) + Passiflora incarnata flower (0.225 ml) + Peppermint (0.05 ml)Solution / dropsOralBio Strath Ag1989-12-312008-07-24Canada
Dormiphen Au NaturelValerian (400 mg) + Passiflora incarnata flower (400 mg)CapsuleOralLaboratoire Lalco Inc.Not applicableNot applicableCanada
Herbal Nerve - TabletValerian (300 mg) + Scutellaria lateriflora (350 mg)TabletOralSwiss Herbal Remedies Ltd.1995-12-312009-08-04Canada
Herbal Nerve TabValerian (50 mg) + Hops (50 mg) + Scutellaria lateriflora (100 mg)TabletOralVita Health Products Inc1977-12-312005-07-20Canada
Herbal RelaxValerian (120 mg) + Chamomile (460 mg)CapsuleOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1998-11-052002-07-29Canada
Herbal Relaxant - TabletValerian (500 mg) + Chamomile (200 mg)TabletOralQuest Vitamins A Div Of Purity Life Health Products1995-12-312001-07-06Canada
Herbal SleepValerian (600 mg) + Chamomile (100 mg) + Hops (165 mg) + Passiflora incarnata flower (175 mg)CapsuleOralPuresource Inc.Not applicableNot applicableCanada
Herbal Sleep AidValerian (400 mg) + Hops (100 mg) + Passiflora incarnata flower (100 mg)CapsuleOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1998-11-052002-07-29Canada
Herbal Slumber CapValerian (177 mg) + Hops (67 mg) + Peppermint (153 mg) + Scutellaria lateriflora (153 mg)CapsuleOralPep Products Inc.1992-12-311999-10-29Canada
Hops-valerian Combination CapValerian (133 mg) + Hops (134 mg) + Scutellaria lateriflora (133 mg)CapsuleOralNature's Herbs Inc.1995-12-311997-05-30Canada
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Medi-doze Rx Sleep AidValerian (50 mg/1) + Melatonin (6 mg/1) + gamma-Aminobutyric acid (30 mg/1)TabletOralTwo Hip Consulting, Llc2013-02-202016-04-11Us
Categories
UNII
JWF5YAW3QW
CAS number
8057-49-6

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
2,5-Dimethoxy-4-ethylthioamphetamineThe risk or severity of adverse effects can be increased when Valerian is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Valerian.
4-MethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Methoxyamphetamine is combined with Valerian.
5-methoxy-N,N-dimethyltryptamineThe risk or severity of adverse effects can be increased when Valerian is combined with 5-methoxy-N,N-dimethyltryptamine.
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Valerian.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of adverse effects can be increased when 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is combined with Valerian.
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Valerian.
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Valerian.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Valerian.
AcetophenazineThe risk or severity of adverse effects can be increased when Acetophenazine is combined with Valerian.
Additional Data Available
  • Extended Description
    Extended Description

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  • Severity
    Severity

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

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Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911444
Wikipedia
Valerian
ATC Codes
N05CM09 — Valerianae radix
AHFS Codes
  • 92:01.00* — Herbs and Natural Products
  • 28:24.92 — Miscellaneous Anxiolytics Sedatives and Hypnotics

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Unknown StatusTreatmentAnxiety Disorders1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Solution / dropsOral
LiquidOral
TabletOral
CapsuleOral
PowderOral
TinctureOral
TabletOral
CapsuleOral
LiquidOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on June 23, 2017 14:37 / Updated on October 23, 2019 15:32