Showing BioInteractions for alpha-Tocopherol succinate (DB14001)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Glutathione S-transferase A2 inducer
1Glutathione S-transferase A2 substratesAzathioprine, Busulfan, Glutathione
2Glutathione S-transferase A2 inducersD-alpha-Tocopherol acetate, Vitamin E
3Glutathione S-transferase A2 inhibitorsClofibrate, Etacrynic acid
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Glutathione S-transferase P inhibitor
1Glutathione S-transferase P inhibitorsClomipramine, Curcumin, D-alpha-Tocopherol acetate, Etacrynic acid, Exisulind, Vitamin E
2Glutathione S-transferase P substratesAcetaminophen, Busulfan, Carboplatin, Chlorambucil, Cisplatin, Etoposide, Oxaliplatin
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Glutathione S-transferase omega-1 inhibitor
1Glutathione S-transferase omega-1 inhibitorsD-alpha-Tocopherol acetate, Vitamin E
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Glutathione S-transferase Mu 3 inducer
1Glutathione S-transferase Mu 3 inducersD-alpha-Tocopherol acetate, Vitamin E
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Glutamate--cysteine ligase catalytic subunit inducer
1Glutamate--cysteine ligase catalytic subunit inducersD-alpha-Tocopherol acetate, Vitamin E
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a NAD(P)H dehydrogenase [quinone] 1 inducer
1NAD(P)H dehydrogenase [quinone] 1 inhibitorsCannabidiol, Dicoumarol
2NAD(P)H dehydrogenase [quinone] 1 inducersD-alpha-Tocopherol acetate, Vitamin E
3NAD(P)H dehydrogenase [quinone] 1 substratesCarboplatin, Cisplatin, Doxorubicin, Oxaliplatin, Phenytoin
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Heme oxygenase 1 inducer
1Heme oxygenase 1 inducersD-alpha-Tocopherol acetate, Polaprezinc, Vitamin E
Interacting GroupInteracting Drugs
alpha-Tocopherol succinate is a Superoxide dismutase [Cu-Zn] inducer
1Superoxide dismutase [Cu-Zn] inducersD-alpha-Tocopherol acetate, Polaprezinc, Vitamin E
2Superoxide dismutase [Cu-Zn] substratesCisplatin, Oxaliplatin
3Superoxide dismutase [Cu-Zn] inhibitorsCannabidiol, Carboplatin, Medical Cannabis, Nabiximols
4Superoxide dismutase [Cu-Zn] cofactorsCopper, Zinc chloride
5Superoxide dismutase [Cu-Zn] ligandsZinc acetate