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Displaying drugs 76 - 100 of 15489 in total
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations ... Drug-Related Side Effects and Adverse Reactions …
Matched Products: … Ciprofloxacin and Dextrose ... CIPROFLOXACIN HCL MONOHYDRATE ... C-ZIN …
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Synonyms: … polystyrenesulfonic acid ... Polystyrene sulfonic acid ... poly(styrene-4-sulfonic acid) …
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Synonyms: … Suberanilohydroxamic acid ... Suberoylanilide hydroxamic acid ... Octanedioic acid hydroxyamide phenylamide …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … R & C Shampoo With Conditioner ... Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer …
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … 13-cis-retinoic acid ... Neovitamin A acid ... 13-cis-Vitamin A acid
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under …
Matched Categories: … Skin and Mucous Membrane Agents …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Categories: … Amino Acids, Peptides, and Proteins ... gamma-Aminobutyric Acid-ergic Agonist …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … L-Folinic acid ... (6S)-Folinic acid ... Levofolinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … acid or leucovorin). ... Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic ... acid antagonists, such as methotrexate, which act by inhibiting the enzyme dihydrofolate reductase ( …
Matched Categories: … Folic Acid and Derivatives ... Folic Acid Analogues ... Enzymes and Coenzymes …
Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective...
Approved
Matched Synonyms: … Mepenzolic acid
Matched Description: … Mepenzolate diminishes gastric acid and pepsin secretion. ... It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. …
Matched Categories: … Alimentary Tract and Metabolism …
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Synonyms: … Allylbarbituric acid ... iso-butylallylbarbituric acid ... 5-allyl-5-isobutylbarbituric acid
Matched Description: … Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid ... , acetaminophen, aspirin, and caffeine. …
Matched Mixtures name: … Trianal C½ ... Trianal C¼ ... Fiorinal-C 1/4 …
Matched Categories: … Hypnotics and Sedatives …
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 3-(4-Phenylbenzoyl)propionic acid ... 4-(4-Biphenylyl)-4-oxobutyric acid ... 3-(4-Biphenylylcarbonyl)propionic acid
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid
Matched Description: … It can also be used to relieve backaches, sprains, and fractures. ... anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and ... Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … Fumaric acid, dimethyl ester ... (E)-But-2-enedioic acid dimethyl ester ... trans-Butenedioic acid dimethyl ester …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Carbolic acid ... Phenic Acid ... Phenylic acid
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (S)-α-amino-1H-indole-3-propanoic acid ... (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... (S)-alpha-Amino-beta-(3-indolyl)-propionic acid
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Numeta G 19 % E Emulsion zur Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Matched Categories: … bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... High-Ceiling Diuretics and Potassium-Sparing Agents …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … Cephaoglycin acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid ... 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid
Matched Iupac: … acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Salts name: … Cefaloglycin monohydrate
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … Terfenadine acid metabolite ... 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … Allergy and Congestion ... Allergy and Congestion ... Allegra-D Allergy and Congestion …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Salts name: … Calcium gluconate monohydrate
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … HYDROFLUORIC ACID ANTIDOTE GEL 2.5% w/w …
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Synonyms: … Ceftobiprole medocaril free acid
Matched Iupac: … -2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... was subsequently approved in the United States with additional indications for skin and skin structure …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Carbonic acid monosodium salt …
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and
Matched Mixtures name: … GaviLyte - C TM ... Up and Up Antacid and Pain Relief ... PEG-3350 and Electrolytes …
Matched Categories: … Carbonic Acid ... Gastric Acid Lowering Agents ... Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-mercaptoethanesulfonic acid ... 2-mercaptoethanesulphonic acid ... β-mercaptoethanesulfonic acid
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid
Matched Description: … used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. ... Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations …
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ... [(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … -7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Salts name: … Cefalexin monohydrate
Matched Products: … NIXELAF-C ... CEFALEXIN MONOHYDRATE
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in ... the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Categories: … Fatty Acid Derivatives …
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Synonyms: … Phenobarbituric Acid ... Phenylethylbarbituric Acid ... 5-Ethyl-5-phenylbarbituric acid
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents ... A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists ... Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Displaying drugs 76 - 100 of 15489 in total