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The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Insulin-like growth factor 2 ... Insulin-like growth factor-2 ... Insulin-like growth factor-II …
Matched Name: … Insulin-like growth factor II …
Matched Description: … This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... the liver and to circulate in the blood. ... It is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … B-domain deleted recombinant factor VIII ... Human factor VIII, recombinant B-domain deleted ... Antihemophilic factor recombinant plasma/albumin free …
Matched Description: … factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma ... purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Exogenous replacement of Factor VIII is currently the cornerstone of Hemophilia treatment and is used …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Blood Coagulation Factors
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … INSULIN-LIKE GROWTH FACTOR 1 ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … Factor VIII (antihaemophilic factor) ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … , a long-lived plasma protein [A31551]. ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... The small amount of VWF:Ag is used to purify factor VIII complex and then removed from the final preparation …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Factor VIII ... Biological Factors ... Blood Coagulation Factors
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... Beriate 250 IU Powder and solvent for solution for injection or infusion ... FACTOR VIII 500 IU FLAKON, 1 ADET …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and ... effect and modulation of the microbial composition of the dental biofilm [A19581]. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Anticavity Toothpaste Multi Function ... Sensodyne Sensitivity and Gum Clean and Fresh ... Crest Sensi-Repair and Prevent …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine ... (S)-3-(N-methylpyrrolidin-2-yl)pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … NIQUITINPARCHE TRANSDERMICO POR 21 MG ETAPA 1 ... NIQUITIN®PARCHE TRANSDERMICO POR 14 MG ETAPA 2 ... Up and Up Nicotine …
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … [L5783] Due to the possibility of fatal overdose and liver failure associated with the incorrect use ... of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. …
Matched Mixtures name: … TYLOL HOT LIKIT GECE ORAL SIVI, 245 ML ... ALPARA ... ALPARA
Matched Categories: … Acetaminophen and Prodrugs ... tramadol and paracetamol ... codeine and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … PORO SUPPOSITORY 250 MG ... Children's Tylenol Sus 160mg/5ml Liq-grape ... Infant's Tylenol Sus 80mg/ml Dps - Grape Fl …
Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Description: … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. …
Matched Mixtures name: … PERS-MANT %19 + %2 JEL (30 G) …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Secret Invisible Glam Grapefruit ... Avon On Duty 24 Plus Solid Antipersp Stk 25% ... Bille-20
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Curel Alpha Hydroxy Dry Skin Lotion ... Cremo All-Season Lip Balm SPF 25 Vanilla Mint ... Mineral Oil, Petrolatum, Phenylephrine Hydrochloride, Shark Liver Oil …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … SOKOL 200 ML ÇÖZELTİ ... Vitamin A and D ... A and D …
PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …
Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin lispro ... Insulina lispro ... insulin lispro-aabc …
Matched Name: … Insulin lispro …
Matched Description: … 1 and Type 2 Diabetes. ... into internal organs and tissues such as the liver, fat cells, and skeletal muscle. ... is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors
Matched Mixtures name: … Humalog Mix 25 (pen) ... Humalog Mix 25 (pen) ... Humalog Mix 25 (cartridge) …
Matched Categories: … Insulins and Analogues for Injection, Fast-Acting ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulin
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen ... Insulin lispro ... Insulin Lispro …
Approved
Matched Synonyms: … (1R,2S,5R)-Menthol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Matched Mixtures name: … Oars and Alps Muscle Recovery Balm ... Qforet Born To Grow ... Blue Ice Fermented Cod Liver Oil Calm Balm …
Matched Products: … Revive 2 ... Pain Relief 2% ... Ez Massager 2 Original …
Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Leaders Mediu 2 Step Double Effect Pore Tightening Mask ... Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … }ethyl]carbamoyl}-2-[(2S)-2-[(2R)-2-[(2R)-3-(4-chlorophenyl)-2-[(2R)-2-acetamido-3-(naphthalen-2-yl)propanamido ... (4S)-N-{4-[(2S)-2-{[(1R)-2-[4-(carbamoylamino)phenyl]-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]carbamoyl}-3-methylbutyl]carbamoyl ... ]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]ethyl]phenyl}-2,6-dioxo-1,3-diazinane …
Matched Description: … gland and blocks interaction with GnRH. ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... FDA approved on December 24, 2008. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Synonyms: … Antihemophilic Factor (Recombinant), PEGylated ... antihemophilic factor (recombinant), PEGylated-aucl …
Matched Name: … Antihemophilic factor (recombinant), PEGylated …
Matched Description: … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... with at least one molecule of polyethylene glycol (MW 20 kDa) [FDA label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Blood Coagulation Factors ... Human Antihemophilic Factors
Matched Products: … ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF). ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADET …
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits ... Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... , alpha = 92 residues, beta=111 residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Pituitary Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... Menopur Powder for Injection and Solvent 75 IU ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection …
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Description: … It has bactericidal activity and is used often as a topical disinfectant. ... A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … BODY PRESCRIPTIONS ANTIBACTERIAL HAND SANITIZER 2 Pack PEPPERMINT and WINTER BERRY ... BODY PRESCRIPTIONS ANTIBACTERIAL HAND SANITIZER 2 Pack PEPPERMINT and WINTER BERRY ... 25 Person ANSI …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Susan Winget Berries and Cream Hand Sanitizer ... Certus Recens A ... Oars and Alps Antibacterial Hand Sanitizer Gel …
MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … family receptor tyrosine kinases, ERBB2 and ERBB3. ... MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Iupac: … 1,4,7,10,13,16-hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan-19-yl N-(2- …
Matched Description: … Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. …
Matched Salts cas: … 396091-76-2
Matched Categories: … Sex Hormones and Insulins ... Pituitary and Hypothalamic Hormones and Analogues ... Pituitary Hormone Release Inhibiting Hormones ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues …
Matched Products: … SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR® LAR 20 MG ... SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … cosmetic, hair, and skincare products. ... of the castor oil plant (_Ricinus communis_ L.) mainly cultivated in India, South America, Africa, and ... and mineral oral tablets as an ingredient for protective coatings. …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP ... Minodil hair growth solution …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil ... Eyelash Growth Liquid …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Blood Coagulation Factors
Matched Products: … โนโวเอท 250 หน่วยสากล ... NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. ... Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. …
Matched Categories: … Biological Factors ... Alimentary Tract and Metabolism ... Glucagon-Like Peptide 1 ... Amino Acids, Peptides, and Proteins ... Fluids and Secretions …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG ... BYDUREON® BCISE® 2MG SUSPENSIÓN DE LIBERACIÓN PROLONGADA …
Displaying drugs 51 - 75 of 4870 in total