Showing BioInteractions for Levosimendan (DB00922)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Levosimendan is a Troponin C, slow skeletal and cardiac muscles potentiator | ||
| 1 | Troponin C, slow skeletal and cardiac muscles stimulators | Aluminium monostearate |
| 2 | Troponin C, slow skeletal and cardiac muscles agonists | Calcium |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Levosimendan is a ATP-sensitive inward rectifier potassium channel 11 inducer | ||
| 1 | ATP-sensitive inward rectifier potassium channel 11 inhibitors | Glimepiride, Ibutilide, Isavuconazole, Thiamylal, Verapamil |
| 2 | ATP-sensitive inward rectifier potassium channel 11 inducers | Diazoxide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Levosimendan is a ATP-sensitive inward rectifier potassium channel 8 inducer | ||
| 1 | ATP-sensitive inward rectifier potassium channel 8 inhibitors | Gliquidone, Glisoxepide, Phenformin, Thiamylal |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Levosimendan is a cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor | ||
| 1 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitors | Aminophylline, Amrinone, Anagrelide, Cilostazol, Enoximone, Ibudilast, Milrinone, Oxtriphylline, Theophylline, Tofisopam |