Displaying drugs 26 - 50 of 10320 in total
Pregabalin
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Synonyms: … (S)-3-Isobutyl GABA …
Matched Description: … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized ... , there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent …
Matched Products: … S-pregabalin …
Matched Description: … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized ... , there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent …
Matched Products: … S-pregabalin …
Glutamic acid
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … (S)-Glutamic acid ... (S)-2-Aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET …
Progesterone
Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Synonyms: … (S)-Progesterone ... (S)-4-Pregnene-3,20-dione ... (S)-Pregn-4-en-3,20-dione …
Matched Description: … and is essential for endometrial receptivity, embryo implantation, and the successful establishment of ... acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of ... progesterone is made from a plant source as a starting material and is chemically identical to progesterone of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … ANNEM´S …
Matched Description: … and is essential for endometrial receptivity, embryo implantation, and the successful establishment of ... acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of ... progesterone is made from a plant source as a starting material and is chemically identical to progesterone of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … ANNEM´S …
Sodium lauryl sulfoacetate
Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
Approved
Experimental
Matched Synonyms: … Sulfoacetic acid dodecyl ester S-sodium salt …
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-3,3-dimethylcysteine ... (S)-2-amino-3-mercapto-3-methylbutanoic acid …
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. ... It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties. ... The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine …
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. ... It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties. ... The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … (S)-methionine ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET ... AMINOACIDI S BIOINDUSTRIA L.I.M. …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET ... AMINOACIDI S BIOINDUSTRIA L.I.M. …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … ], a novel inhibitor of C3. ... [A245154] Notably, none of these agents are approved for use in the treatment of CAD. ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies …
Matched Description: … ], a novel inhibitor of C3. ... [A245154] Notably, none of these agents are approved for use in the treatment of CAD. ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … therapy of 93-99% depending on genotype and level of cirrhosis [L852]. ... Lack of significant side effects and short duration of therapy is a considerable advantage over older ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … therapy of 93-99% depending on genotype and level of cirrhosis [L852]. ... Lack of significant side effects and short duration of therapy is a considerable advantage over older ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma …
Matched Categories: … Antivirals for treatment of HCV infections …
Technetium Tc-99m disofenin
Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Description: … suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …
Benzphetamine
A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … (S)-benzphetamine ... (S)-(+)-benzphetamine ... (S)-(+)-N-benzyl-N,α-dimethylphenethylamine …
Matched Description: … It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222) …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Description: … It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222) …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Estazolam
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … of the drug which may lead to coma and death. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects …
Matched Mixtures name: … NEUPAX DUO-S …
Matched Description: … of the drug which may lead to coma and death. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects …
Matched Mixtures name: … NEUPAX DUO-S …
Pramipexole
Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Synonyms: … (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine …
Matched Description: … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of ... Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). ... The prevalence of Parkinson's Disease worldwide has increased from approximately 2.5 million in 1990 …
Matched Products: … PRAMIPEXOLO SANDOZ A/S …
Matched Description: … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of ... Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). ... The prevalence of Parkinson's Disease worldwide has increased from approximately 2.5 million in 1990 …
Matched Products: … PRAMIPEXOLO SANDOZ A/S …
Altretamine
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Synonyms: … 2,4,6-tris(dimethylamino)-s-triazine …
Technetium Tc-99m sestamibi
Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium ... emission computed tomography (SPECT) is then performed to detect the gamma ray emmitted by the decay of ... The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …
Dexbrompheniramine
Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Approved
Matched Synonyms: … (S)-brompheniramine ... (S)-(+)-brompheniramine …
Matched Description: … Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions …
Matched Description: … Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions …
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Synonyms: … N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide …
Matched Description: … are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of ... [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Description: … are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of ... [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Description: … One of them is the induction of cytotoxicity. ... subcutaneously for the treatment of MDS of all French-American-British (FAB) subtypes. ... [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved …
Matched Description: … One of them is the induction of cytotoxicity. ... subcutaneously for the treatment of MDS of all French-American-British (FAB) subtypes. ... [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved …
Betiatide
Approved
Experimental
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide …
CVac
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Dimethyl sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Matched Description: … of pharmaceuticals. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application ... Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Matched Description: … of pharmaceuticals. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application ... Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Milk thistle
Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Fruit of Silybum Marianum …
Asparagine
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … (S)-Asparagine ... (S)-2-amino-3-carbamoylpropanoic acid …
Matched Description: … A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain …
Matched Description: … A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … (S)-pyroglutamic acid ... (S)-(−)-2-pyrrolidone-5-carboxylic acid …
Matched Description: … Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... is included in some over-the-counter, non-prescription dietary supplements for the proposed purpose of …
Matched Description: … Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... is included in some over-the-counter, non-prescription dietary supplements for the proposed purpose of …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Displaying drugs 26 - 50 of 10320 in total