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Displaying drugs 551 - 575 of 670 in total
A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Synonyms: … 1,2-dimethoxy-12-methyl(1,3)dioxolo)4',5':4,5)benzo(1,2-c)phenanthridinium …
Experimental
Matched Name: … 6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE …
Experimental
Matched Name: … 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid …
Experimental
Matched Name: … 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID …
Matched Iupac: … 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-3-yl)benzoic acid …
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Investigational
Matched Synonyms: … 2-(4-Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
Experimental
Matched Name: … 5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine …
Matched Iupac: … 5H,6H-benzo[h]cinnolin-3-amine …
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … O-benzoyl-(-)-ecgonine …
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran …
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Approved
Experimental
Matched Synonyms: … Morpholinylmercapto-benzo-thiazole …
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Name: … 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid …
Matched Iupac: … 3-{5-[(1Z)-2-nitropent-1-en-1-yl]furan-2-yl}benzoic acid …
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Synonyms: … (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine …
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … chlorothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Investigational
Matched Synonyms: … (2r,3s)-2-(3-(4,5-dichloro-1h-benzo(d)imidazol-1-yl)propyl)piperidin-3-ol …
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione …
Matched Description: … , Frisium, Urbanyl, and others. ... children aged two years and older. ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Experimental
Matched Name: … 8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine …
Experimental
Matched Name: … (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL …
Matched Iupac: … (2R,3R,4R)-1H,2H,3H,4H-benzo[c]phenanthrene-2,3,4-triol …
Experimental
Matched Synonyms: … 4-hydroxy-2H-benzo[b]pyran-2-one …
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary …
Matched Mixtures name: … Heel Balm ... BALISA VAS ... BALISA VAS …
Matched Categories: … Blood and Blood Forming Organs ... Emollients and Protectives ... Blood Substitutes and Perfusion Solutions …
Matched Products: … BALISA
Experimental
Matched Name: … 3-(5-amino-7-hydroxy-(1,2,3)triazolo(4,5-d)pyrimidin-2-yl)benzoic acid …
Matched Iupac: … 3-{5-amino-7-hydroxy-2H-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl}benzoic acid …
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide …
Matched Description: … Benzthiazide is used to treat hypertension and edema. ... Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency …
Matched Mixtures name: … TOLAK ®3 TABLETAS RECUBIERTAS ... TOLAK ®3 TABLETAS RECUBIERTAS ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz …
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Description: … therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and ... forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and ... Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Androgens and Estrogens ... Pituitary and Hypothalamic Hormones and Analogues ... Antiandrogens and Estrogens ... etynodiol and estrogen ... dienogest and estrogen …
Matched Products: … Alora ... ALORA
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ALOND 50MG CÁPSULAS ... ALOND® 75MG CAPSULAS ... ALOND® 25 MG CAPSULAS …
Experimental
Matched Name: … 2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid …
Matched Iupac: … 2-(1-carboxy-N-{4-[(2S)-2-acetamido-2-(pentylcarbamoyl)ethyl]naphthalen-1-yl}formamido)benzoic acid …
Displaying drugs 551 - 575 of 670 in total